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Advances in the molecular genetics of parathyroid tumors

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Chinese Medical Journal 2024年第3期137卷 376-378页

作者： Liwei Zhao Xianghui he Department of General Surgery Tianjin Medical University General HospitalTianjin 300052China

To the Editor:Parathyroid tumors are endocrine tumors that can lead to disorders of calcium and phosphorus metabolism and involve multiple organ *** the past,the genetics of parathyroid tumors have been well established,and the significant roles of genes such as MEN1,CDC73,and CCND1 in the process of parathyroid tumorigenesis have been identified and confirmed[Table 1].However,with further research and the widespread use of sequencing technology,“new”roles for“old”genes and new pathogenic mechanisms have been discovered.

关键词： metabolism tumors parathyroid

Electrolyte effect on electrochemical behaviors of manganese fluoride material for aqueous asymmetric and symmetric supercapacitors

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Rare Metals 2024年第3期43卷 1048-1061页

作者： Zheng-Hua he Jian-Fei Gao Ling-Bin Kong State Key Laboratory of Advanced Processing and Recycling of Non-Ferrous Metals Lanzhou University of TechnologyLanzhou730050China School of Materials Science and Engineering Lanzhou University of TechnologyLanzhou730050China

Exploring wide voltage window materials is not only an available measure to enhance the energy density of hybrid supercapacitor(HSCs),but also avoids the dynamic mismatch caused by different energy storage mechanisms of two electrodes in assembled symmetrical ***,there are few reports about the wide potential window materials except Bi_(2)O_(3)and VO_(2).Therefore,the MnF_(2)synthesized by solvothermal reaction was served as the electrode for *** MnF_(2)exhibited electrochemical activity in alkaline solution in three-electrode system,especially with a wide potential window from-0.8 to+0.5 V in 2 mol·L^(-1)***,the assembled MnF_(2)//MnF_(2)symmetrical HSC had a potential window of 1.5 V,and it exhibited outstanding long-cycle ***,when MnF_(2)was taken as the negative and positive respectively,the potential windows of asymmetric devices CoMoO_(4)//MnF_(2)and MnF_(2)//Activated Carbon(AC)could reach 1.3 and 1.45 V,respectively,showing excellent cycle *** work shows that MnF_(2)material has great research value in HSC,and provides a new research direction for developing high-performance devices.

关键词： Manganese fluoride Potential window Hybrid supercapacitors Electrochemical performance

Mitigating gut immune adverse effects in CTLA-4 blockade for antitumor efficacy

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Science China(Life Sciences) 2024年第7期67卷 1539-1541页

作者： Shijun he Jianping Zuo Zemin Lin Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese MedicineShanghai 201203China School of Pharmacy University of Chinese Academy of SciencesBeijing 100049China

By creating an immune checkpoint blockade-induced colitis model,Lo et al.(2024)have suggested a strategy for alleviating gastrointestinal immune-related adverse events while preserving the antitumor stimulatory effect... 详细信息

关键词： immune gastrointestinal

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Layer by Layer Self-assembly Fiber-based Flexible Electrochemical Transistor

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Journal of Wuhan University of Technology(Materials Science) 2024年第4期39卷 937-944页

作者：谭艳 HAO Panpan he Yang ZHU Rufeng 王跃丹 School of Biomedical Engineering Hubei University of MedicineShiyan 442000China Key Laboratory of Textile Fiber and Products Ministry of EducationWuhan Textile UniversityWuhan 430200China

Poly(3,4-ethylenedioxyethiophene)-polystyrene sulfonic acid(PEDOT:PSS)/polyallyl dimethyl ammonium chloride modified reduced graphene oxide(PDDA-rGO)was layer by layer self-assembled on the cotton *** surface morphology and electric property was *** results confirmed the dense membrane of PEDOT:PSS and the lamellar structure of PDDA-rGO on the *** has excellent electrical conductivity and mechanical *** fiber based electrochemical transistor(FECTs)prepared by the composite conductive fiber has a maximum output current of 8.7 mA,a transconductance peak of 10 mS,an on time of 1.37 s,an off time of 1.6 s and excellent switching *** importantly,the devices by layer by layer self-assembly technology opens a path for the true integration of organic electronics with traditional textile technologies and materials,laying the foundation for their later widespread application.

关键词： layer by layer self-assembly fiber based organic electrochemical transistor reduced graphene oxide PEDOT:PSS

Carbon allocation in Picea jezoensis:Adaptation strategies of a non-treeline species at its upper elevation limit

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Forest Ecosystems 2024年第3期11卷 347-357页

作者： Renkai Dong Na Li Mai-he Li Yu Cong Haibo Du Decai Gao Hong S.he Key Laboratory of Geographical Processes and Ecological Security in Changbai Mountains Ministry of EducationSchool of Geographical SciencesNortheast Normal UniversityChangchun130024China School of Natural Resources University of MissouriColumbiaMO65211USA Swiss Federal Institute for Forest Snow and Landscape Research WSL8903BirmensdorfSwitzerland Northeast Institute of Geography and Agricultural Ecology Chinese Academy of SciencesChangchun130102China School of Life Science Hebei UniversityBaoding071002China

Understanding the physiological adaptations of non-treeline trees to environmental stress is important to understand future shifts in species composition and distribution of current treeline *** aim of the present study was to elucidate the mechanisms of the formation of the upper elevation limit of non-treeline tree species,Picea jezoensis,and the carbon allocation strategies of the species on Changbai *** employed the^(13)C in situ pulse labeling technique to trace the distribution of photosynthetically assimilated carbon in Picea jezoensis at different elevational positions(tree species at its upper elevation limit(TSAUE,1,700 m a.s.l.)under treeline ecotone;tree species at a lower elevation position(TSALE,1,400 m a.s.l.).We analyzed^(13)C and the non-structural carbohydrate(NSC)concentrations in various tissues following *** findings revealed a significant shift in carbon allocation in TSAUE compared to *** was a pronounced increase inδ^(13)C allocation to belowground components(roots,soil,soil respiration)in TSAUE compared to ***,the C flow rate within the plant-soil-atmosphere system was faster,and the C residence time in the plant was shorter in *** trends indicate enhanced C sink activity in belowground tissues in TSAUE,with newly assimilated C being preferentially directed there,suggesting a more conservative C allocation strategy by *** at higher elevations under harsher *** a strategy,prioritizing C storage in roots,likely aids in withstanding winter cold stress at the expense of aboveground growth during the growing season,leading to reduced growth of TSAUE compared to *** results of the present study shed light on the adaptive mechanisms governing the upper elevation limits of non-treeline trees,and enhances our understanding of how non-treeline species might respond to ongoing climate change.

关键词： ^(13)C pulse labeling Carbon distribution Non-structural carbohydrates(NSC) Non-treeline species Sink activity Stressful environments Upper elevation limit

Design of double protograph LDPC codes based JSCC systems via the ACE-PEG algorithm

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Science China(Information Sciences) 2024年第7期67卷 339-340页

作者： Yijie LV Jiguang he Shaohua HONG Department of Information and Communication Engineering Xiamen University Technology Innovation Institute Centre for Wireless Communications Oulu University

In this study, we present a state-of-the-art design of double protograph low-density parity-check (DP-LDPC) codes based on progressive edge-growth (PEG) algorithm with approximated cycle extrinsic message degree (ACE)... 详细信息

关键词： Benchmarking

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Lifetime-tunable circularly polarized luminescent system based on triplet-to-singlet F?rster resonance energy transfer

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Science China Chemistry 2024年第9期67卷 2918-2922页

作者： Zhenyi he Zizhao Huang Xiang Ma Key Laboratory for Advanced Materials and Feringa Nobel Prize Scientist Joint Research Center Institute of Fine Chemicals School of Chemistry and Molecular Engineering East China University of Science and Technology

Circularly polarized luminescence(CPL) materials have received widespread attention due to their remarkable performance and broad applications. However, current CPL material research primarily focuses on tunable color, intensity, and *** CPL with adjustable lifetime remains a significant challenge. herein, a series of CPL polymeric materials with tunable lifetime were obtained by employing phosphorescent terephthalic acid and chiral organic small molecule R/S-BNAF(a luminescent binaphthol derivative) to copolymerize with acrylamide in different ratios. It was verified that this performance results from the different energy transfer efficiency between luminophores with varying ratios of the monomers for copolymerization. This strategy to realize CPL with tunable lifetime by modulating the energy transfer efficiency will provide a new perspective to broaden the applications of CPL materials.

关键词： circularly polarized luminescence tunable lifetime Förster resonance energy transfer room temperature phosphorescence

Increased glacier melt enhances future extreme floods in the southern Tibetan Plateau

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Advances in Climate Change Research 2024年第3期15卷 431-441页

作者： he SUN Tan-Dong YAO Feng-Ge SU Tinghai Ou Zhihua he Guoqiang TANG Deliang CheN State Key Laboratory of Tibetan Plateau Earth System Environment and Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China Regional Climate Group Department of Earth SciencesUniversity of GothenburgGothenburg 40530Sweden Centre for Hydrology University of SaskatchewanSaskatoon S7N 1K2Canada Climate and Global Dynamics National Center for Atmospheric ResearchBoulder CO 80307USA

Mountainous areas are of special hydrological concern because topography and atmospheric conditions can result in large and sudden floods,posing serious risks to water-related safety in neighbouring *** Yarlung Zangbo(YZ)River basin is the largest river basin on the Tibetan Plateau(TP),but how floods will discharge in this basin and how the role of glacier melt in floods will change throughout the 21st-century under shared socioeconomic pathways scenarios(SSP2-4.5 and SSP5-8.5)remain ***,we comprehensively address this scientific question based on a well-validated large-scale glacier-hydrology *** results indicate that extreme floods was projected to increase in the YZ basin,and was mainly reflected in increased duration(4–10 d per decade)and intensity(153–985 m^(3)s^(−1)per decade).Glacier runoff was projected to increase(2–30 mm per decade)throughout the 21st-century,but there was also a noticeable decrease or deceleration in glacier runoff growth in the late first half of the century under the SSP2-4.5,and in the latter half of the century under the *** melt was projected to enhance the duration(12%–23%)and intensity(15%–21%)of extreme floods under both SSPs,which would aggravate the impact of future floods on the socioeconomics of the YZ *** effect was gradually overwhelmed by precipitation-induced floods from glacier areas to YZ *** study takes the YZ basin as a projection framework example to help enrich the understanding of future flood hazards in basins affected by rainfall-or meltwater across the TP,and to help policy-makers and water managers develop future plans.

关键词： floods glacier Tibetan

A lightweight false alarm suppression method in heterogeneous change detection

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Journal of Systems Engineering and Electronics 2024年第4期35卷 899-905页

作者： XU Cong he Zishu LIU Haicheng School of Electronic and Information Engineering Heilongjiang Institute of EngineeringHarbin 150026China School of Information and Communication Engineering University of Electronic Science and Technology of ChinaChengdu 611731China

Overlooking the issue of false alarm suppression in heterogeneous change detection leads to inferior detection *** paper proposes a method to handle false alarms in heterogeneous change detection.A lightweight network of two channels is bulit based on the combination of convolutional neural network(CNN)and graph convolutional network(GCN).CNNs learn feature difference maps of multitemporal images,and attention modules adaptively fuse CNN-based and graph-based features for different *** with a new kernel filter adaptively distinguish between nodes with the same and those with different labels,generating change *** evaluation on two datasets validates the efficacy of the pro-posed method in addressing false alarms.

关键词： convolutional neural network(CNN) graph convolu-tional network(GCN) heterogeneous change detection lightweight false alarm suppression