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Solitary Retinal Astrocytoma: A Case Series

Open Journal of Pathology 2013年第2期3卷 60-64页

作者： Takafumi Fuchino Tomayoshi Hayashi Kiyoshi Suzuma Asuka Taneoka Kuniko Abe Naoe Kinoshita haruna yasui Takashi Kitaoka Junya Fukuoka Department of Pathology Nagasaki University Hospital Nagasaki Japan

Background: Astrocytic tumors of the retina are rare. We report and discuss the clinical features of two cases of retinal astrocytoma along with presenting a current literature review. Case Presentation: Case 1 was a 46-year-old Japanese female who became aware of her decreased visual acuity. A fundus photograph indicated the presence of a 5 mm hemispherical yellow-white tumor, retinal edema and hard exudate around the tumor. In case 2, a 36-year-old Japanese female became aware of her myodesopsia, and presented with a retinal tumor and vitreous hemorrhage in her right eye. Since the tumors occurred in the peripheral retina in both cases, endoresections were performed. Histological examination showed that the tumors were composed of spindle-shaped cells with small nuclei, which was consistent with astrocytes. Conclusion: Pathologically, it can be difficult to differentiate astrocytic tumors. Therefore, when making a diagnosis, it is important that comprehensive examinations be done in conjunction with the clinical findings. Since retinal astrocytoma has a favorable prognosis, provided proper treatment is administered, utilization of endoresection for peripheral astrocytoma may be advantageous in this patient group.

关键词： Retina Astrocytoma Pathology

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Ossified thoracic spinal meningioma with hematopoiesis: A case report and review of the literature

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Case Reports in Clinical Medicine 2013年第1期2卷 24-28页

作者： Asuka Taneoka Tomayoshi Hayashi Takayuki Matsuo Kuniko Abe Naoe Kinoshita haruna yasui Takafumi Fuchino Izumi Nagata Junya Fukuoka Department of Neurosurgery Nagasaki University Hospital Nagasaki Japan Department of Pathology Nagasaki University Hospital Nagasaki Japan

Meningiomas account for 25% of spinal tumors, and they are often located in the thoracic spine. The ossified subtype is even rarer, and those with hematopoiesis are rarely described. The mechanism of bone formation has not yet been clarified. A case of ossified spinal meningioma with hematopoiesis occurring in a 78-year-old woman is described. Magnetic resonance imaging revealed a lesion with a dural tail sign at the T9 level located dorsal to the spinal cord. Computerized tomography revealed a high density lesion, as high as the bone signal. Total resection was performed, and the symptoms improved. Pathological findings revealed many psammoma bodies (PBs), bone formation, and bone marrow with hematopoiesis. Both PBs and bone seemed to be based on the same background of calcified structures. This report is the second dealing with ossified spinal meningioma with hematopoiesis. The hardness of the tumor can make the operation more difficult, so that the operation should be performed carefully to avoid injuring the spinal cord.

关键词： Spinal Cord Meningioma Ossification Extramedullary Hematopoiesis Spinal Tumor

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