检索结果-南通市图书馆

Effects of nitroprusside sodium to prevent cell cycle arrest induced in A172 human glioma cells by X-ray irradiation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

辐射研究与辐射工艺学报 2005年第2期23卷 94-94页

作者： QIURong LlWenjian haojifang LIUBing ZHANGHong LISha InstituteofModernPhysics ChineseAcademyofSciencesLanzhou730000 RadiotherapyDepartment GeneralHospitalofLanzhouMilitaryAreaLanzhou730050

Nitric oxide (NO) has been implicated both in regression and progression of tumors due to its production by both tumor cells and infiltrating leukocytes. Ionizing radiation causes the regression of tumors, and can augment the production of NO by macrophages in vitro. The authors investigated the effect of X-ray irradiation on cell cycle of A172 human glioma cells pretreated with nitroprusside sodium (NPS), the NO *** glioma A172 cells were maintained in RPMI-1640 medium supplemented with 10% heat-inactive fetal calf serum in a 5 % CO2 incubator at 37 ℃. The experiment was performed in exponentially growing *** cells in cell culture flasks treated with or without 1 mM NPS for 4 h. were irradiated to a dose of 4 Gy X-rays using 8MeV CL 2100C electron linear accelerator (Varian, USA) in General Hospital of Lanzhou Military *** the irradiation, the cells were collected by trypsinization, washed with phosphate buffer solution, f1xed in 70 % ethanol, treated with RNase and the nuclei were stained with propidium iodide. The DNA content was evaluated using Becton Dickinson FACSCalibur and analyzed with UMCM cylchred cell cycle analyzer *** cell culture medium was replaced after irradiation and cells were harvested 24h later, labeled with propidium iodide and analyzed by flow cytometry. After the 4 Gy X-ray irradiation, the cell cycle distribution of A172 glioma cells changed markedly, with increased percentage of G2/M cells and decreased of G0/G1 and S cells compared to control cells(Fig. 1 a, lb). The cells pretreated with 1 mM NPS 4 h displayed similar cell cycle distributions to those of the control (Fig. lc). But X-ray irradiated cells preincubated with 1 mM NPS showed different cell cycle distributions from those of unpretreated cells (Fig. 1 d).It was reported that NO or NO release agents were as effective as oxygen to radiosensitize hypoxic cells in vitro. It was also revealed that NO involved in the resistance to ionizing radiation b

关键词：硝普钠氮氧化物细胞循环辐射医学神经胶质瘤

Location Determination of Ion Track Hitting Rice Seed Loaded in Shenzhou 3

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

近代物理研究所和兰州重离子加速器实验室年报：英文版 2002年第1期 65-65页

作者： WeiZengquan XieHongmei MeiMantong haojifang MaQiufeng MaoShuhong 不详 BioteclmologyCollege SouthChinaofAgriculturalUniversity.

In order to get a clear understanding of the mechanism of space radiation breeding, a detecting system was manufactured. The system consisted of 3 boards of rice seeds (1# and 2# for Qinghua non-glutinous rice and 3# for Pearl early rice, Huiyang) and 10 layers of solid state nuclear track detectors (CR-39) in sandwich (Fig.1). It was loaded in space shuttle Shenzhou 3 (at astronaut seat) in the last 10-day period of March, 2002.

关键词： “神舟”三号水稻种子离子径迹定位测量宇宙射线辐射中国农业大学太空离子

Improvement of Herbage by Heavy Ion Beams

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

近代物理研究所和兰州重离子加速器实验室年报：英文版 2002年第1期 71-71页

作者： XieHongmei haojifang WeiZengquan XieZhongkui LiFengqin WangYajun InstituteofColdandAridEnvironmentandEngineering theChineseAcademyofSciencesLanzhou. 不详

Herbage seeds of legume and grass (Defu, American fine stem spread alkaline grass and so on) were penetrated with 80 MeV/u 20Ne10+ ions supplied by HIRFL, NLHIAL. Average LET in plateau of Bragg curve of the ions was 120 keV/μm. Irradiation dose was 40, 60, 80, 100, 150 Gy for leguminous herbage and 15, 20, 30, 40, 50 Gy for grass herbage. Dose rate of irradiation was 3 Gy/min. Irradiation was carried out in atmosphere. Some of irradiated seeds were sown in the fields and others were used to do experiments for cytology.

关键词：重离子束牧草改良豆科牧草禾科牧草染色体改变

Response of Alanine Dosemeter to Heavy Ions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

近代物理研究所和兰州重离子加速器实验室年报：英文版 2003年第1期 76-76页

作者： LiWenjian SuXu YangYingjie YuanJianlei DangBingrong WangXiao MaQiufeng ZhouLibin haojifang MaoShuhong 不详 NationalInstituteforRadiologicalProtection ChineseCenterforDiseaseControlandPrevention.

The amino acid L-α-alanine has been investigated for use as a radiation detector in low and high LET radiation fields[1]. The radiatioa detector is cheap and easy to handle. The radiation inducing free radicals are stable at normal laboratory conditions for doses below 10^4 Gy over a long period of time, which makes the detector useful for intercomparison and documentation purposes. The dosimetric features of alanine-based electron spin resonance (ESR) detectors in high energy electron beams used in radiotherapy were considered[2]. The 5 mm long alanine detectors were found to be the most suitable for carrying out in vivo dosimetry on patients undergoing electron beam radiotherapy. However, data concerning dosimetry of the alanine dosemeter to heavy charged particles are lacking, especially in China.

关键词：丙胺酸药物剂量重离子氨基酸放射性探测