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A micro-chip exploding foil initiator based on printed circuit board technology

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Defence Technology（防务技术） 2022年第8期18卷 1435-1444页

作者： Zhi Yang Peng Zhu Qing-yun Chu Qiu Zhang Ke Wang hao-tian jian Rui-qi Shen School of Chemical Engineering Nanjing University of Science and TechnologyNanjing210094China Micro-Nano Energetic Devices Key Laboratory Ministry of Industry and Information TechnologyNanjing210094China

Conventional exploding foil initiator (EFI) in ignition or detonation applications hosts many performance advantages, but was hindered by the bulky, inaccurate, inefficient and expensive shortcomings. We highlight a novel micro-chip exploding foil initiator (McEFI) using printed circuit board (PCB) technology. The structural parameters were determined based on energy coupling relationship at the component interfaces. Next, the prototype McEFI has been batch-fabricated using PCB technology, with a monolithic structure of 7.0 mm (l) × 4.5 mm (w) × 4.0 mm (δ). As expected, this PCB-McEFI illustrated the successful firing validations for explosives pellets. This paper has addressed the cost problem in both military munitions and civil markets wherever reliable, insensitive and timing-dependent ignition or detonation are involved.

关键词： Exploding foil initiator Printed circuit board Monolithic structure Firing validations

A reusable planar triggered spark-gap switch batched-fabricated with PCB technology for medium- and low-voltage pulse power systems

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Defence Technology（防务技术） 2021年第4期17卷 1572-1578页

作者： Zhi Yang Ke Wang Peng Zhu Peng Liu Qiu Zhang Cong Xu hao-tian jian Rui-qi Shen School of Chemical Engineering Nanjing University of Science and TechnologyNanjing210094China Key Laboratory of Special Energy Materials Ministry of EducationNanjing210094China Micro-Nano Energetic Devices Key Laboratory Ministry of Industry and Information TechnologyNanjing210094China

Triggered spark-gap switch is a popular discharge switch for pulse power *** studies have focused on planarizing this switch using thin film techniques in order to meet the requirements of compact size in the *** switches are one-shot due to electrodes being too thin to sufficiently resist ***,these switches did not employ any structures in securing internal gas composition,resulting in inconsistent performance under harsh *** this work,a novel planar triggered spark-gap switch(PTS)with a hermetically sealed cavity was batched-prepared with printed circuit board(PCB)technology,to achieve reusability with low *** proposed PTS was inspected by micro-computed tomography to ensure PCB techniques meet the requirements of machining *** results from electrical experiments demonstrated that PCB PTS were consistent and reusable with lifespan over 20 *** calculated switch voltage and circuit current were consistent with those derived from real-world ***,PCB PTS was used to introduce hexanitrostilbene(HNS)pellets in a pulse power system to verify its performance.

关键词： Pulse power systems Printed circuit board technology Triggered spark-gap switch Planar discharge switch Electrical performance

Phase regulated suppression and enhancement switches of four-wave mixing and fluorescence

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Frontiers of physics 2014年第2期9卷 153-156页

作者： Zhi-Guo Wang Peng Ying Pei-Ying Li Hua-Yan Lan He-Qing Huang hao tian jian-Ping Song Yan-Peng Zhang Key Laboratory for Physical Electronics and Devices of the Ministry of Education Shaanxi Key Lab of Information Photonic Technique Xi'an Jiaotong University Xi'an 710049 China

We experimentally study the phase regulated switch between elcctromagnctically induced trans- parency and electromagmetically induced absorption in probe transmission signal and the conver- sion between enhancement and suppression in four-wave mixing and fluorescence signals for the first time. By changing the relative phase, electromagnetically induced transparency can be eonverted into electromagnetically induced absorption. In this process, the conversion from suppression to enhancement is also obtained in four-wave mixing and fluorescence signals. This research can be applied in non-linear optical device like optical switch and optical wavelength convertor.

关键词： four-wave mixing fluorescence phase regulation enhancement and suppression

Slowed vesicle priming and enhanced synaptic depression at syntaxin1B deficient calyceal synapses

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Slowed vesicle priming and enhanced synaptic depression at s...

Transforming waste particles into valuable adsorbents via amyloid-mediated molecular engineering

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： jian-Li GUO,Xue-Feng WANG,hao tian,jian-Yuan SUN~* Institute of Biophysics,Chinese Academy of Sciences,State Key Laboratory of Brain and Cognitive Science,Beijing 100101,China

＜正＞Syntaxin 1（STX1）,including STX1A and STX1B,is a SNARE protein located at presynaptic membrane and considered to be critical for synaptic vesicle priming and ***,the previous studies have shown that homozygous STX1A KO mice exhibited no significant phenotype in both synaptic vesicle release and animal survival. To determine whether/how STX1B functions in vesicle priming and release kinetics,a STX1B hypomorph mouse line （XT1B） was ***-cell patch clamp recordings from these STX1B mutant Calyx of Held synapses showed fewer spontaneous EPSC（mEPSC） and widened action potential-evoked EPSC（eEPSC）.Under train stimulations, STX1B mutation caused reduction of the eEPSC amplitude at steady state and the enhancement of synaptic depression. Furthermore,STX1B deficiency largely slowed the recovery of RRP after depletion,suggesting the impairment of vesicle *** summary,this study shows that syntaxin 1B protein,as a critical determinant of vesicle release efficiency,modulates releasable vesicle priming and vesicle exocytosis.

关键词： Syntaxin 1B exocytosis priming synapse short term plasticity

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Science China Chemistry 2025年第01期 317-328页

作者： Qingmin Yang jian Zhao Yujia Zhang Xingyu Zhou hao Ren Bowen Hu Zhongli Lei Lixin Chen Peng Yang School of Material and Chemical Engineering Bengbu University Anhui Provincial Engineering Laboratory of Silicon-Based Materials School of Chemistry and Chemical Engineering Northwestern Polytechnical University Key Laboratory of Applied Surface and Colloid Chemistry Ministry of Education School of Chemistry and Chemical EngineeringShaanxi Normal University Xi'an Key Laboratory of Polymeric Soft Matter School of Chemistry and Chemical Engineering Shaanxi Normal University International Joint Research Center on Functional Fiber and Soft Smart Textile School of Chemistry and Chemical EngineeringShaanxi Normal University

The high-value utilization of industrial solid waste using a facile and eco-friendly process is of great interest and significance in reducing environmental pollution and developing a green circular economy. Herein, we propose an amyloid-mediated molecular engineering strategy to transform particulate waste into valuable adsorbents for metal ions. Our method has the advantage of aqueous solution fabrication under mild conditions without the use of high-temperature hydrothermal methods and toxic chemical reagents. Amyloid-mediated molecular engineering manipulates the phase transition of bovine serum albumin(BSA)on particulate waste surfaces, resulting in a remarkable ～3.1 times improvement in the adsorption capacity of fly ash, a typical industrial solid waste for gold ions after modification with the phase-transitioned BSA(PTB). The resultant adsorption ability was 69–1,980 times higher than those of conventional and emerging adsorbent materials such as ion exchange resins, activated carbon(AC), covalent organic frameworks(COFs), and metal-organic frameworks(MOFs). We further demonstrated the application of our PTB-modified materials in the recovery of precious metals from low-grade gold ore and electronic waste leachates. Consequently, this strategy could increase the value of waste materials nearly 27 times. In addition, this method is generally extendable to other conventional industrial adsorbents such as resin, clay, and Al2O3, and enhances their adsorption capabilities at least twofold. Overall, this work provides a simple and green approach for improving the adsorption performance of solid particles, and is expected to develop into a universal strategy for transforming waste particles into high-value-added products.

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Recent progress in the applications of presynaptic dopaminergic positron emission tomography imaging in parkinsonism

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Neural Regeneration Research 2025年第1期20卷 93-106页

作者： Yujie Yang Xinyi Li Jiaying Lu Jingjie Ge Mingjia Chen Ruixin Yao Mei tian jian Wang Fengtao Liu Chuantao Zuo Key Laboratory of Arrhythmias Ministry of EducationDepartment of Medical GeneticsShanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina Department of Neurology National Research Center for Aging and MedicineNational Center for Neurological Disordersand State Key Laboratory of Medical NeurobiologyHuashan HospitalFudan UniversityShanghaiChina Department of Nuclear Medicine&PET Center National Center for Neurological Disordersand National Clinical Research Center for Aging and MedicineHuashan HospitalFudan UniversityShanghaiChina International Human Phenome Institutes(Shanghai) ShanghaiChina Human Phenome Institute Fudan UniversityShanghaiChina

Nowadays,presynaptic dopaminergic positron emission tomography,which assesses deficiencies in dopamine synthesis,storage,and transport,is widely utilized for early diagnosis and differential diagnosis of *** review provides a comprehensive summary of the latest developments in the application of presynaptic dopaminergic positron emission tomography imaging in disorders that manifest *** conducted a thorough literature search using reputable databases such as PubMed and Web of *** criteria involved identifying peer-reviewed articles published within the last 5 years,with emphasis on their relevance to clinical *** findings from these studies highlight that presynaptic dopaminergic positron emission tomography has demonstrated potential not only in diagnosing and differentiating various Parkinsonian conditions but also in assessing disease severity and predicting ***,when employed in conjunction with other imaging modalities and advanced analytical methods,presynaptic dopaminergic positron emission tomography has been validated as a reliable in vivo *** validation extends to screening and exploring potential neuropathological mechanisms associated with dopaminergic *** summary,the insights gained from interpreting these studies are crucial for enhancing the effectiveness of preclinical investigations and clinical trials,ultimately advancing toward the goals of neuroregeneration in parkinsonian disorders.

关键词： aromatic amino acid decarboxylase brain imaging dopamine transporter Parkinson’s disease parkinsonism positron emission tomography presynaptic dopaminergic function vesicle monoamine transporter type 2

Clinicopathological differences between patients with schistosomal appendicitis and non schistosomal appendicitis:A retrospectively study of past ten years

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World Journal of Clinical Cases 2025年第2期13卷 24-32页

作者： Xiao-Yi Wang Yao hao Zi-jian Wang Xiu-Liang Xu jiang-Hua Yang Department of Infectious Diseases The First Affiliated of Wannan Medical CollegeWuhu 241001Anhui ProvinceChina

BACKGROUND Chronic schistosomiasis causes multiple organ and multiple system diseases,especially the digestive *** eggs are mainly deposited in the stomach,liver and colorectal,but a few eggs are deposited in the appendix and cause *** present,there are few studies on schistosomal *** To explore the differences in epidemiological,clinical and pathological characteristics between schistosomal appendicitis and non-schistosomal appendicitis over the past decade in order to assess the impact of schistosomiasis on *** The differences of general data,clinical data and laboratory examination data of patients with appendicitis from October 2013 to October 2023 were retrospectively *** patients were divided into two groups for *** were 136 patients in schistosomal appendicitis group and 5418 patients in non-schistosomal appendicitis *** Schistosomal appendicitis accounted for 2.45%of all patients with appendicitis,and the annual proportion in the past decade was 2.2%,2.9%,1.8%,1.9%,3.4%,3.1%,1.9%,1.6%,3%,2.6%,*** prevalence of schistosomal appendicitis was middle-aged and elderly males,with an average age of 61.73±15.335 *** main population of non-schistosomal appendicitis was middle-aged men,with an average age of 35.8±24.013 years(P<0.001).The distribution of pathological types of appendicitis was different between the two groups(P<0.001).The incidence of acute suppurative appendicitis in non-schistosomal appendicitis was higher than that in schistosomal appendicitis[odds ratio(OR)=0.504;95%confidence interval(CI):0.349-0.728;P<0.001].The proportion of acute attack of chronic appendicitis in schistosomal appendicitis was higher than that in non-schistosomal appendicitis(OR=2.614;95%CI:1.815-3.763;P<0.001).The proportion of schistosomal appendicitis patients complicated with colorectal cancer was higher than that of nonschistosomal appendicitis patients(OR=5.087;95%CI:1.427-

关键词： Schistosomal appendicitis Schistosomiasis Appendix Colorectal cancer Clinicopathological characteristics

基于KML实现公路外业勘测快速导航定点的方法

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西部交通科技 2017年第10期 24-26页

作者：谢作勤韦浩莫天健广西交通科学研究院有限公司广西南宁530007

文章将KML地理信息标记文件导入智能便携定位设备,实现快速、高效的公路外业导航定位,节省外业工作时间,并以融水至河池高速公路勘测项目为例,介绍了该定位设备的具体操作方法。

关键词：公路外业勘测 KML 定位导航智能便携设备方法

Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening

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Science China Life Sciences 2025年第1期 300-302页

作者： Ze-Min Lin Mai Xiang Wen-Hui Wei Shu-Hui Fan Li Chen Jie Wang Xiao-Qian Yang Chun-hao Yang Shi-Jun He jian-Ping Zuo Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of Sciences School of Pharmacy University of Chinese Academy of Sciences School of Pharmacy Nanjing University of Chinese Medicine State Key Laboratory of Drug Research Department of Medicinal ChemistryShanghai Institute of Materia MedicaChinese Academy of Sciences Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Experiment Center for Science and Technology Shanghai University of Traditional Chinese Medicine

Dear Editor, Phenotypic drug discovery, which observes compound effects on physiology,has given way to targeting specific molecules, but has revived by using modern methods to find drugs based on therapeutic outcomes in disease models(Vincent et al., 2022). Osteoarthritis(OA) is a prevalent chronic joint disorder, primarily affecting knee joints, with osteoclast activation due to low-grade inflammation resulting in increased bone resorption and structural changes in the joint(Katz et al.,2021).

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