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基于公平关注的供应链库存管理效率评价研究

物流工程与管理 2024年第5期46卷 31-35,59页

作者：张霞蕊林萍朱卫未南京邮电大学管理学院江苏南京210000 南京邮电大学高质量发展评价研究院信息产业融合创新与应急管理研究中心江苏南京210000 江苏科技大学经济管理学院江苏镇江212100

库存协调是供应链管理中至关重要的组成部分,有助于增强供应链的韧性和效率。为解决库存积压、供应链中断等问题,文中通过改进链接控制DEA方法,在其中嵌入Context-dependent,并基于各方利益最大化冲突引入公平关注,构建三方利益协调机... 详细信息

库存协调是供应链管理中至关重要的组成部分,有助于增强供应链的韧性和效率。为解决库存积压、供应链中断等问题,文中通过改进链接控制DEA方法,在其中嵌入Context-dependent,并基于各方利益最大化冲突引入公平关注,构建三方利益协调机制的改进三阶段DEA模型。研究结果表明,对DEA模型进行改进后,整体效率明显提高,各个决策单元(DMU)之间的差距也有所减小;同时,在加入公平关注效用之后,排序更加准确,避免了出现多个DMU效率相等的情况;针对中间库存差异较大的供应链,成功确定了有效的调整措施。

关键词：供应链库存管理多主体协调公平关注效用链接控制DEA

miR-200b-3p accelerates progression of pituitary adenomas by negatively regulating expression of RECK

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Oncology Research 2024年第5期32卷 933-941页

作者： XIAOXI WANG YANFEI JIA QIANG LI QIANG YANG YINGFENG LIU BEIFENG wei XIANG NIU YINJIE ZHANG XIAODONG LUO ZIYU Zhao PENG WANG Department of Neurosurgery Tianshui First People’s HospitalTianshuiChina Department of Neurosurgery The Second Affiliated Hospital of Lanzhou UniversityLanzhouChina

MicroRNA(miR)-200b-3p has been associated with many tumors,but its involvement in pituitary adenoma is *** study investigated the molecular mechanism underlying miR-200b-3p regulation in pituitary adenomas to provide a theoretical basis for *** was used to analyze pituitary adenoma-related genes and screen new targets related to RECK and *** well,the relationship between miR-200b-3p and RECK protein was verified using a double-luciferase reporter gene *** expression of miR-200b-3p in clinical samples was analyzed by in situ *** of the miR-200b-3p inhibitor and small interfering-RECK(si-RECK)was verified by ***3 cell viability and proliferation were detected using CCK8 and EdU *** was detected by flow cytometry and western *** healing and Transwell assays were used to detect cell migration and *** effects of miR-200b-3p and RECK on GH3 cells were verified using salvage ***-200b-3p was highly expressed in pituitary tumor *** of miR-200b-3p inhibited cell proliferation promoted cell apoptosis,inhibited invasion and migration,and inhibited the expression of matrix ***,miR-200b-3p negatively regulated *** expression of RECK in pituitary adenoma tissues was lower than that in neighboring ***-RECK rescued the function of miR-200b-3p inhibitors in the above cellular behaviors,and miR-200b-3p accelerated the development of pituitary adenoma by negatively regulating RECK *** summary,this study investigated the molecular mechanism by which miR-200b-3p regulates the progression of pituitary adenoma through the negative regulation of *** findings provide a new target for the treatment of pituitary adenoma.

关键词： Pituitary adenomas miR-200b-3p RECK Matrix metalloproteinase

Multi-site Passivation of ZnO Metal Oxides via Biomolecules for Efficient and Highly Stable Organic Solar Cells

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Chinese Journal of Chemistry 2024年第14期42卷 1582-1592页

作者： Irfan Ismail Maria Khalil Xiaomei Gao Xingze Chen Muhammad Jawad Rong Huang Zhiyun Li Emmanuel Acheampong Tsiwah wei-shi Li Qun Luo Chang-Qi Ma i-Lab&Printable Electronics Research Center Suzhou Institute of Nano-Tech and Nano-Bionics(SINANO)Chinese Academy of Sciences(CAS)SuzhouJiangsu215123 China University of Chinese Academy of Sciences(UCAS) Beijing100040 China School of Nano-Tech and Nano-Bionics University of Science and Technology of China(USTC)HefeiAnhui230027 China Shanghai Institute of Organic Chemistry(SIOC) Chinese Academy of Sciences(CAS)Shanghai200032 China Vacuum Interconnected Nanotech Workstation(Nano-X) SuzhouJiangsu215123 China

ZnO nanoparticles(nps)among metal oxide(MOs)are proven to be essential electron transporting layers(ETLs)applied in organic solar cells(OSCs).However,intrinsic defects,interfacial charge recombination,and catalytic behavior towards the active layer restrict the applications of ZnO nps for efficient and long-term stable *** commonly available biomolecule cytidine 5'-monophosphate(CMP-OH)with phosphonic acid,its salt cytidine 5'-monophosphate disodium salt(CMP-ONa)with a phosphate group as an anchoring group and conjugated terminal functional in both analogous molecules provide carrier transfer bridge at bottom interface of the active *** theoretical investigations and characterizations have discovered the multi-site coordination of CMP-OH towards acceptor molecules and ZnO *** dual-side alignment of CMP analogous molecules hinders interfacial charge recombination and enhances charge transfer potential at ***,PM6:L8-BO-based OSCs with modified ETL obtain 18.13%efficiency,12%higher than that of unmodified *** higher efficiency,CMP-OH-based OSC devices illustrate remarkably improved thermal stability for 500 h at 85℃with 72%of initial PCE and operation stability for 2000 h with 90.1%of initial *** work reveals the passivation mechanism of multi-anchoring groups towards MOs and single-functional groups towards the active layer to optimize the interface for efficient and highly stable OSCs.

关键词： Organic solar cells Nanoparticles Nucleotides Interfacial interactions Surface chemistry Multi-site passivation

Alterations in the gut microbiome after transjugular intrahepatic portosystemic shunt in patients with hepatitis B virus-related portal hypertension

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World Journal of Gastroenterology 2024年第31期30卷 3668-3679页

作者： Hong-wei Zhao Jin-Long Zhang Fu-Quan Liu Zhen-Dong Yue Lei Wang Yu Zhang Cheng-Bin Dong Zhen-Chang Wang Department of Radiology Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Department of Radiology Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Department of Interventional Radiology Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China

BACKGROUND Gut microbiota(GM)affects the progression and response to treatment in liver *** GM composition is diverse and associated with different etiologies of liver ***,alterations in GM alterations are observed in patients with portal hypertension(PH)secondary to cirrhosis,with hepatitis B virus(HBV)infection being a major cause of cirrhosis in ***,understanding the role of GM alterations in patients with HBV infection-related PH is *** To evaluate GM alterations in patients with HBV-related PH after transjugular intrahepatic portosystemic shunt(TIPS)*** This was a prospective,observational clinical *** were 30 patients(with a 100%technical success rate)recruited in the present *** with esophagogastric variceal bleeding due to HBV infection-associated PH who underwent TIPS were *** samples were obtained before and one month after TIPS treatment,and GM was analyzed using 16S ribosomal RNA amplicon *** One month after TIPS placement,8 patients developed hepatic encephalopathy(HE)and were assigned to the HE group;the other 22 patients were assigned to the non-HE *** was no substantial disparity in the abundance of GM at the phylum level between the two groups,regardless of TIPS treatment(all,P>0.05).However,following TIPS placement,the following results were observed:(1)The abundance of Haemophilus and Eggerthella increased,whereas that of Anaerostipes,Dialister,Butyricicoccus,and Oscillospira declined in the HE group;(2)The richness of Eggerthella,Streptococcus,and Bilophila increased,whereas that of Roseburia and Ruminococcus decreased in the non-HE group;and(3)Members from the pathogenic genus Morganella appeared in the HE group but not in the non-HE *** Intestinal microbiota-related synergism may predict the risk of HE following TIPS placement in patients with HBVrelated *** microbiome therapies may be useful for preventing and trea

关键词： Transjugular intrahepatic portosystemic shunt Hepatic encephalopathy Gut microbiota Hepatitis B virus Portal hypertension

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地震作用下的干法赤泥堆场稳定性分析

应用力学学报 2024年第3期41卷 651-658页

作者：卢玉林何金泽陈晓冉王丽林玮防灾科技学院土木工程学院北京101601 中国地震局建筑物破坏机理与防御重点实验室北京101601 防灾科技学院地质工程学院北京101601

地震是影响赤泥堆体场稳定性的重要因素之一。采用有限元强度折减法和规范指导方法对龙塔崖沟干法赤泥堆场进行了静力稳定性分析,确定了滑动面的位置和形状,计算了静力条件下的安全系数。以拟静力法不同烈度工况下的堆积体安全系数为标... 详细信息

地震是影响赤泥堆体场稳定性的重要因素之一。采用有限元强度折减法和规范指导方法对龙塔崖沟干法赤泥堆场进行了静力稳定性分析,确定了滑动面的位置和形状,计算了静力条件下的安全系数。以拟静力法不同烈度工况下的堆积体安全系数为标定值,分析了两条实测地震波作用下的堆积体位移、加速度以及动力安全系数的变化规律,计算结果满足规范设定的阈值,可确定堆积体是稳定的。通过与不同方法、不同规范的评价要求对比,判定有限元强度折减法可作为稳定性分析的评价标尺。

关键词：赤泥堆场干法地震稳定性

肉鸡源传染性法氏囊病新型重排毒株的分离鉴定及遗传进化分析

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西南农业学报 2024年第4期37卷 890-896页

作者：左文博蒲德粉王威威王林果韦平何秀苗广西民族大学海洋与生物技术学院/广西多糖材料与改性重点实验室南宁530006 广西大学养禽与禽病学研究所南宁530005 普莱柯生物工程股份有限公司河南洛阳471000

[目的]明确云南某肉鸡场疑似传染性法氏囊病病毒(IBDV)感染病例的病原类型及分子特征,以了解IBDV新型重排毒株在肉鸡中的流行情况、分子进化趋势,为制定有效的传染性法氏囊病(IBD)防控和疫苗选用策略提供参考依据。[方法]对疑似IBDV感... 详细信息

[目的]明确云南某肉鸡场疑似传染性法氏囊病病毒(IBDV)感染病例的病原类型及分子特征,以了解IBDV新型重排毒株在肉鸡中的流行情况、分子进化趋势,为制定有效的传染性法氏囊病(IBD)防控和疫苗选用策略提供参考依据。[方法]对疑似IBDV感染的病鸡法氏囊进行研磨处理后,采用巢式RT-PCR进行检测,后将IBDV阳性的法氏囊组织悬液接种于9日龄SPF鸡胚并进行病毒分离,对病毒的vVP2和VP1-b基因扩增并进行遗传变异分析。[结果]成功分离出一株新型IBDV重排毒株(命名为YN-YX221110),接种9日龄SPF鸡胚后,胚体整体呈现弥漫性出血,头、颈以及背部皮肤有出血点。基于vVP2基因序列,分离株YN-YX221110与新型变异株(nvIBDV)参考株的核苷酸相似性最高,为93.2%~97.9%,分离株YN-YX221110的vVP2基因222A特征性氨基酸位点与UK661、HK46等超强毒株(vvIBDV)参考株相同,249K、256V、279N、284A、294L、299S等位点与新型变异株(nvIBDV)参考株中的SHG19相同;在基于vVP2基因的遗传进化树中,分离株YN-YX221110与GX-QZ191002、SHG19等nvIBDV参考株聚为一支,属于A2d分支。基于VP1-b基因序列,分离株YN-YX221110与参考株中的经典毒株(cIBDV)类似株核苷酸相似性最高,为97.8%~98.4%,分离株YN-YX221110的vVP2基因特征性氨基酸位点240D、242D、287T、390L和393E与致弱毒株(attIBDV)参考株中的B87、Gt相同;在基于VP1-b基因序列的系统发育进化树中,分离株YN-YX221110与参考株Gt、B87和CEF94等cIBDV类似株中的attIBDV聚为一支,属于B1a分支。分离株YN-YX221110基因型为A2dB1a。[结论]成功分离得到肉鸡源IBDV分离株YN-YX221110,其A片段来源于nvIBDV,B片段来源于cIBDV类似株中的attIBDV,为新型IBDV重排毒株。

关键词：传染性法氏囊病病毒(IBDV) 新型变异株分离鉴定基因重排分子遗传进化

Industrial utilization of arsenic-containing gold dressing tailings as pellet prepared by straight grate process

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Journal of Central South University 2024年第6期31卷 1888-1899页

作者： LIU wei GUO Zheng-qi ZHU De-qing PAN Jian ZHANG Wu-ju WANG Jin ZHANG Ying-qun YIN Fu-xing School of Minerals Processing and Bioengineering Central South UniversityChangsha 410083China Low-carbon and Hydrogen Metallurgy Research Center Central South UniversityChangsha 410083China Heqing Beiya Mining Co. Ltd.Dali 671507China

The utilization of arsenic-containing gold dressing tailings is an urgent issue faced by gold production companies *** thermodynamic analysis results indicate that ferrous arsenate(FeAsO_(4)),pyrite(FeS_(2))and sodium cyanide(NaCN)in the arsenic-containing gold metallurgical tailings can be effectively removed using straight grate process,and the removal of pyrite and sodium cyanide is basically completed during the preheating stage,while the removal of ferrous arsenate requires the roasting *** pellets undergo a transformation from magnetite to hematite during the preheating process,and are solidified through micro-crystalline bonding and high-temperature recrystallization of hematite(Fe_(2)O_(3))during the roasting ***,pellets with removal rates of 80.77% for arsenic,88.78% for sulfur,and 99.88% for cyanide are obtained,as well as the iron content is 61.1% and the compressive strength is 3071 N,meeting the requirements for blast furnace *** study provides an industrially feasible method for treating arsenic-containing gold smelting tailings,benefiting gold production enterprises.

关键词： arsenic-containing gold dressing tailings pelletizing straight grate process recycling

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具有泡沫金属流场的燃料电池研究进展

新能源进展 2024年第1期12卷 24-34页

作者：艾贤魏魏琳郭剑车帅蒋方明沈阳化工大学机械与动力工程学院沈阳110142 中国科学院广州能源研究所广州510640 中国科学院可再生能源重点实验室广州510640

泡沫金属是一种具有高孔隙率、高电导率、良好传热性和重量较轻等优点的新型多功能材料,在质子交换膜燃料电池(PEMFC)中嵌入泡沫金属作为流场的应用受到越来越多的关注。重点综述PEMFC流场的研究进展,探讨泡沫金属结构参数、流场设计和... 详细信息

泡沫金属是一种具有高孔隙率、高电导率、良好传热性和重量较轻等优点的新型多功能材料,在质子交换膜燃料电池(PEMFC)中嵌入泡沫金属作为流场的应用受到越来越多的关注。重点综述PEMFC流场的研究进展,探讨泡沫金属结构参数、流场设计和环境因素等对功率密度、气体分布、压降和水热管理等性能的影响。进一步讨论泡沫金属流场在PEMFC应用中所面临的腐蚀和水淹问题,以及具备耐腐蚀涂层泡沫金属的研究进展,为PEMFC泡沫金属流场的发展和优化提供有益的启示,以期推进泡沫金属在PEMFC中的应用。

关键词：泡沫金属质子交换膜燃料电池流场设计腐蚀水热管理

Dual innervation method to preserve erectile function following prostatectomy

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Chinese Journal of Plastic and Reconstructive Surgery 2024年第3期6卷 159-160页

作者： Nadia Hui Shan Sim Allen Sim Dayna Sim Bien-Keem Tan Allen wei-Jiat Wong Plastic Reconstructive and Aesthetic Surgery ServiceSengkang General Hospital544886Singapore Department of Urology Mount Alvernia Hospital Singapore574623Singapore Department of General Surgery Sengkang General Hospital544886Singapore Department of Plastic Reconstructive and Aesthetic SurgerySingapore General Hospital169608Singapore

Prostate cancer is the second most prevalent cancer in ***-assisted radical prostatectomy(RARP)has altered the landscape of prostate cancer *** the excellent oncological outcomes associated with RARP,the rate of erectile dysfunction(ED)remains *** repair of disrupted cavernous nerves with interpositional nerve grafts has been described;however,the outcomes have been *** hypothesize that this is attributed to Schwann cell atrophy and axonal regeneration limitations caused by long nerve *** proposed the use of nerve transfer to support axonal regrowth via an inter-positional graft with additional donor axons.A cadaveric study was performed to evaluate the anatomical feasibility of a vastus lateralis nerve(VLN)transfer to the distal recipient cavernous nerve *** VLN is long with multiple branching patterns that allow tension-free coaptation of the cavernous *** postulate that a dual innervation method using VLN nerve transfer together with interpositional nerve graft repair of the transacted cavernous nerves may improve the outcomes of ED post-RARP.

关键词： Erectile dysfunction Prostatectomy Interposition nerve graft Nerve transfer Vastus lateralis nerve