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1例输入性类鼻疽的病原学诊断及溯源分析

中国人兽共患病学报 2024年第1期40卷 76-81页

作者：杨红霞王春雨王洋郝瑞娥赵启玉郑霄山西省疾病预防控制中心重点传染性疾病预防与诊治山西省重点实验室太原030012 山西省人民医院太原030012 太原市疾病预防控制中心太原030032 中国疾病预防控制中心传染病预防控制所传染病预防控制国家重点实验室北京102206

目的对1例输入性类鼻疽患者进行病原学诊断及溯源分析,为山西省类鼻疽防控提供科学依据。方法患者血培养阳性,分离菌株鉴定为泰国伯克霍尔德菌。采用生化试验及微生物质谱仪进行菌株鉴定,核酸提取后进行全基因组测序,分析MLST型和耐药... 详细信息

目的对1例输入性类鼻疽患者进行病原学诊断及溯源分析,为山西省类鼻疽防控提供科学依据。方法患者血培养阳性,分离菌株鉴定为泰国伯克霍尔德菌。采用生化试验及微生物质谱仪进行菌株鉴定,核酸提取后进行全基因组测序,分析MLST型和耐药基因携带情况,同时构建系统进化树。结果此次分离株经生化试验及微生物质谱仪检测均鉴定为类鼻疽伯克霍尔德菌,MLST型为ST366,全基因测序分析与海南省3个分离株进化亲缘关系较近,同源性较高。结论此例类鼻疽病例经分子溯源分析及流行病学调查确定为海南省输入,提示医疗机构及疾控部门应加强对类鼻疽的认识,提高诊疗能力。

关键词：类鼻疽类鼻疽伯克霍尔德菌 MLST分型全基因测序分子溯源

Tick-borne Pathogens in Shanxi Province, China

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Biomedical and environmental Sciences 2021年第5期34卷 410-415页

作者： YANG Xiao Na YANG Hui Jun ZHANG Lin HOU Xue Xia MIAO Guang Qing CAO Hong Bing hao rui e hao Qin State Key Laboratory for Infectious Disease Prevention and Control National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China Shanxi Provincial Center for Disease Control and Prevention Taiyuan 030012ShanxiChina

Ticks are recognized as one of the most important vectors that cause diseases in animals and humans,and have significant public health impacts worldwide[1].They have a wide range of hosts among terrestrial vertebrates,including mammals,birds,*** numerous zoonotic pathogens transmitted by ticks are the causative agents of Lyme disease,rickettsiosis,ehrlichioses,relapsing fever,Q fever,and *** of tick-borne diseases are increasing around the world and some emerging or re-emerging pathogens are being discovered,which pose great challenges for prevention and control.

关键词： prevention Shanxi birds

Construction of multifunctional lanthanum manganese mixed nanoparticles mediated by ionic liquids for selective aerobic oxidation of cyclohexane

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Rare Metals 2024年第5期43卷 2205-2221页

作者： hao Li rui-rui Zhang Ke-Xin Li Shuang Wei Yu-Mei Liu rui-Xia Liu Beijing Key Laboratory of Ionic Liquids Clean Process CAS Key Laboratory of Green Process and EngineeringState Key Laboratory of Multiphase Complex SystemsInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

Selective oxidation of alkanes to produce highvalue chemicals is an essential strategy and means to realize efficient utilization of *** this work,a strategy of lanthanum manganese mixed metal oxides(LMMO)regulated via a facile ionic liquid(IL)-assisted hydrothermal method was proposed to construct the multifunctional catalysts,which exhibited excellent catalytic performance in the selective aerobic oxidation of *** 8.9%cyclohexane conversion with 90%KA oi(cyclohexanol and cyclohexanone)selectivity was achieved over the optimal LMMO catalyst under mild *** effects of anion type,carbon chain length and concentration of ILs on the structure and properties of catalysts were investigated through various characterizations,indicating the structure-directing and template effect of ILs on the multifunctional *** formation of self-assembled spherical nanoparticles followed the"dissolution-nucleation-proliferation"mechanism with the introduction of 1-butyl-3-methylimidazolium hydrogen sulfate,ascribing the synergistic effect between the microenvironment of ILs and the hydrothermal ***,the high reactive oxygen concentration redox capacity,and suitable basic sites of LMMO catalysts mediated by ILs enhance the activation of C-H bonds and molecular oxygen,simultaneously influencing the adsorption and desorption of the substrate.A comprehensive understanding of the high KA oil selectivity and radical reaction mechanism was elucidated based on in situ diffuse reflectance infrared Fourier transform spectroscopy(DRIFTS)and radical trapping *** recycling and regeneration experiments further illuminated that the removal of adsorbed cyclohexanone acting on the LMMO catalyst was the key to achieve high KA oil selectivity.

关键词： Ionic liquids Nanoparticle Multifunctional catalyst Cyclohexane oxidation

Agronomic performances of biodegradable and non-biodegradable plastic film mulching on a maize cropping system in the semi-arid Loess Plateau,China

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Pedosphere 2024年第1期34卷 88-96页

作者： hao ZHANG Mengqiong CHeN ruiquan QIAO Fan DING hao FeNG rui JIANG Research Center for Cultural Landscape Protection and ecological Restoration China-Portugal Belt and Road Cooperation Laboratory of Cultural Heritage Conservation ScienceGold Mantis School of ArchitectureSoochow UniversitySuzhou 215006China Key Laboratory of Plant Nutrition and the Agri-environment in Northwest China Ministry of AgricultureCollege of Natural Resources and EnvironmentNorthwest A&F UniversityYangling 712100China College of Land and environment Shenyang Agricultural UniversityShenyang 110866China Institute of Soil and Water Conservation Northwest A&F UniversityYangling 712100China

Biodegradable plastic film mulch (PFM) is considered an alternative to non-biodegradable PFM to mitigate the negative impacts of residual ***,the agronomic performance of biodegradable PFM in comparison to non-biodegradable PFM still needs to be *** this study,we evaluated the effects of biodegradable and non-biodegradable PFM on soil physicochemical properties,microbial community,and enzyme activities,as well as maize growth *** and non-biodegradable PFM both increased soil temperature,water content,N content,and microbial biomass and maize yield by up to 30%,but decreased soil enzyme activities as compared to no mulching (control,CK).Most soil physicochemical properties,microbial community,and enzyme activities were similar under non-biodegradable and biodegradable PFM at the early stages of maize ***,at the late stages,soil temperature,water content,mineral N,NO_(3)^(-)-N,ammonia monooxygenase (AMO) activity,and total phospholipid fatty acids (PLFAs) decreased under biodegradable PFM owing to film *** PFM increased soil temperature,water content,and total PLFAs at the early stages of maize growth but decreased soil mineral N and total PLFAs at the late stages,as compared to black *** soil temperature and N availability were the major factors affecting soil microbial community,microbial activity decreased after the fragmentation of biodegradable PFM,owing to the decreased soil temperature,water content,and mineral ***,biodegradable PFM could decrease NO_(3)^(-)-N accumulation in topsoil by decreasing N transformation due to the lower microbial and N-related enzyme (e.g.,AMO) activities,compared with non-biodegradable PFM,which may avoid negative environmental impacts,such as NO_(3)^(-)-N leaching or gas emission after *** yield,height,aboveground biomass,and N uptake under biodegradable PFM were similar to those under non-biodegradable PFM during maize growth,implying that biodegrad

关键词： black plastic film mulching enzyme activity film fragmentation microbial community phospholipid fatty acid white plastic film mulching

effect of the vortical structures on the hydrodynamic performance of a pitching hydrofoil

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Journal of Hydrodynamics 2024年第2期36卷 406-420页

作者： rui Yuan Hui-yun hao Qin Wu Yun-qing Liu Biao Huang School of Mechanical engineering Beijing Institute of TechnologyBeijing100081China

The objective is to study the vortical structural behaviors of a transient pitching hydrofoil and their effects on the hydrodynamic performance. The pitching motion of the hydrofoil is set to pitch up with an almost constant rate from 5° to 15° and then back to 5°, with the Reynolds number 4.4×10^(5) and the frequency 2 Hz. The results show that the main coherent structures around the pitching hydrofoil include small-scale laminar separation bubble (LSB), large-scale second vortex (SV) and trailing edge vortex (TeV) which are all vortical. The relationship between the vortical structure and the lift is investigated with the finite-domain impulse theory. It indicates that the major part of the lift is contributed by the LSB, whereas the shedding and the formation of the SV and TeV cause the fluctuation of the lift. The proper orthogonal decomposition (POD) method is applied to capture the most energetic modes, revealing that the LSB mode occupies a large amount of energy in the flow field. The dynamic mode decomposition (DMD) method accurately extracts the dominant frequency and modal characteristics, with the first mode corresponding to the mean flow, the second mode corresponding to the LSB structure and the third and fourth modes corresponding to the vortex shedding.

关键词： Hydrodynamics vortical structures finite-domain impulse theory proper orthogonal decomposition(POD) dynamic mode decomposition(DMD) Pitching hydrofoil

Highly efficient labelling of extracellular vesicles for enhanced detection on a microfluidic platform

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Chinese Chemical Letters 2024年第2期35卷 441-445页

作者： Shi Hu rui hao Zitong Yu Huitao Zhang Hui Yang Bionic Sensing and Intelligence Center Institute of Biomedical and Health EngineeringShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China

Developing precise extracellular vesicles(eVs)labelling techniques with minimal disturbance is of great importance to the follow-up eVs detection and ***,currently available methods such as using probes to conjugate phospholipids or membrane proteins have certain limitations due to eV steric hindrance,dye aggregation,***,we present a microfluidic platform to enhance eVs’labelling efficiency and improve their *** platform provides excellent sample throughput and high-efficiency eV labelling at lower label concentrations with an optimized flowing *** cytometry analysis(FCM)and cellular uptake results show that eV labelling by utilizing this platform possesses the merits of a higher labelling efficiency with 64.1%relative improvement than conventional co-incubation method and a lower background ***,this technique maintains eVs’size,morphology and biological *** the recipient cells uptake the eVs treated by the microfluidic platform,the spatial and temporal distribution of eVs in the cells are clearly *** results demonstrate that our method holds great potential in efficient labelling of eVs,which is essential to subsequent eV quantification and analysis.

关键词： Microfluidic platform extracellular vesicles Labelling PKH dye Flow cytometry

Bi-level Multi-leader Multi-follower Stackelberg Game Model for Multi-energy Retail Package Optimization

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Journal of Modern Power Systems and Clean energy 2024年第1期12卷 225-237页

作者： Hongjun Gao Hongjin Pan rui An hao Xiao Yanhong Yang Shuaijia He Junyong Liu the College of electrical engineering Sichuan UniversityChengdu 610065China the electric Power Research Institute State Grid Jiangsu Electric Power CompanyNanjing 211100China the Institute of electrical engineering Chinese Academy of SciencesBeijing 100190China

In the competitive energy market,energy retailers are facing the uncertainties of both energy price and demand,which requires them to formulate reasonable energy purchasing and selling strategies for improving their competitiveness in this ***,the attractive multi-energy retail packages are the key for retailers to increase their ***,combined with incentive means and price signals,five types of multi-energy retail packages such as peak-valley time-of-use(TOU)price package and day-night bundled price package are designed in this paper for *** iterative interactions between retailers and end-users are modeled using a bi-level model of stochastic optimization based on multi-leader multi-follower(MLMF)Stackelberg game,in which retailers are leaders and end-users are *** make decisions to maximize the profit considering the conditional value at risk(CVaR)while end-users optimize the satisfaction of both energy comfort and ***,a distributed algorithm is proposed to obtain the Nash equilibrium of above MLMF Stackelberg game model while the particle swarm optimization(PSO)algorithm and CPLeX solver are applied to solve the optimization model for each participant(retailer or end-user).Numeral results show that the designed retail packages can increase the overall profit of retailers,and the overall satisfaction of industrial users is the highest while that of residential users is the lowest after game interaction.

关键词： Conditional value at risk(CVaR) energy retailer multi-energy retail package design multi-leader multi-follower(MLMF)Stackelberg game satisfaction

Time evolutions of scalar field perturbation in Schwarzschild de-Sitter black hole from einstein-scalar–Gauss–Bonnet theory

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Communications in Theoretical Physics 2024年第1期76卷 76-81页

作者： Cheng Xu Zhen-hao Yang Xiao-Mei Kuang rui-Hong Yue Center for Gravitation and Cosmology College of Physical Science and TechnologyYangzhou UniversityYangzhou225009China

The scalar-free black hole could be unstable against the scalar field perturbation when it is coupled to a Gauss–Bonnet(GB)invariant in a special *** is known that the tachyonic instability in this scenario is triggered by the sufficiently strong GB *** this paper,we focus on the time domain analysis of massive scalar field perturbation around the Schwarzschild de-Sitter black hole in einstein-scalar–Gauss–Bonnet *** analyzing the scalar field propagation,we find that the scalar field will finally grow when the GB coupling is large *** could lead to the instability of the background black ***,we demonstrate how the mass of the scalar field and the GB coupling strength affect the onset of tachyonic instability.

关键词： black hole perturbation scalar-einstein-Gauss-Bonnet gravity time domain evolution me

A chitosan-based antibacterial hydrogel with injectable and self-healing capabilities

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Marine Life Science & Technology 2024年第1期6卷 115-125页

作者： rui Chen Yanan hao Secundo Francesco Xiangzhao Mao Wen-Can Huang State Key Laboratory of Marine Food Processing and Safety Control College of Food Science and EngineeringOcean University of ChinaQingdao 266404China Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology Qingdao 266237China Qingdao Key Laboratory of Food Biotechnology Qingdao 266404China Key Laboratory of Biological Processing of Aquatic Products China National Light IndustryQingdao 266404China Istituto di Scienze e Tecnologie Chimiche“Giulio Natta” Consiglio Nazionale delle Ricerche via Mario Bianco 920131 MilanItaly

The presence of bacteria directly affects wound ***-based hydrogel biomaterials are a solution as they offer advantages for wound-healing applications due to their strong antimicrobial ***,a double-cross-linking chitosanbased hydrogel with antibacterial,self-healing,and injectable properties is *** chitosan was successfully prepared,and the thiolated chitosan molecules were cross-linked by Ag-S coordination to form a supramolecular ***,the amine groups in the thiolated chitosan covalently cross-linked with genipin to further promote hydrogel *** vitro experimental results indicate that hydrogel can release Ag^(+)over an extended time,achieving an antibacterial rate of over 99% against escherichia coli and Staphylococcus *** to the reversible and dynamic feature of Ag-S coordination,an antibacterial hydrogel exhibited injectable and self-healing ***,the hydrogel showed excellent biocompatibility and biodegradability.

关键词： Hydrogel Chitosan Silver ion Cross-linking Antibacterial