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Outcomes of complete surgical repair versus palliative intervention in neonates with Tetralogy of Fallot

Pediatric Investigation 2022年第4期6卷 260-263页

作者： Mohammed Hamzah Hasan FOthman Krystel Chedid Mohammed Alsabri Ibrahim Qattea hany aly Department of Pediatric Critical Care Cleveland Clinic Children’sClevelandOhioUSA Department of Pediatrics Michigan State University/Sparrow Health SystemLansingMichiganUSA Department of Pediatrics Cleveland Clinic Children’sClevelandOhioUSA Department of Pediatrics Brookdale HospitalNew York CityNew YorkUSA Department of Neonatology Cleveland Clinic Children’sClevelandOhioUSA

The ideal surgical approach when managing neonates with Tetralogy of Fallot(TOF)is still controversial.1 In 1945,subclavian artery to pulmonary artery anastomosis was created as palliation for patients with TOF.2 A decade later,Lillehei et al.3 performed the first intracardiac repair for TOF with ventricular septal defect closure and right ventricular outflow obstruction *** surgical and perfusion techniques,as well as the postoperative care,have advanced and evolved since that *** that evolution,the two concepts of surgical interventions had remained the *** is still much debate on what is the ideal surgical approach to infants with TOF,an early primary surgical repair(EPSR)versus a two-staged surgical approach with either an initial temporary shunt for pulmonary blood flow or transcatheter cardiac *** aim of this study was to determine if one strategy had lower mortality than the other and to assess the hospital length of stay and cost of charge in the study groups.

关键词： surgical nates repair

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Cemented versus uncemented stems for revision total hip replacement:A systematic review and meta-analysis

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World Journal of Orthopedics 2023年第8期14卷 630-640页

作者： hany Elbardesy Fitzgerald Anazor Mohammad Mirza Mohamed aly Annis Maatough Department of Trauma and Orthopaedics University of ManitobaWinnipeg MB R3T2N2ManitobaCanada Nottingham University Hospitals NHS Foundation Trust Nottingham NG72UHUnited Kingdom Department of Trauma and Orthopaedics East Kent University Hospitals NHS Foundation TrustAshford TN240LYKentUnited Kingdom Department of Trauma and Orthopaedics Royal National Orthopaedic HospitalLondon HA74LPUnited Kingdom

BACKGROUND The popularity of uncemented stems in revision total hip arthroplasty(THA)has increased in the last *** To assess the outcomes of both cemented and uncemented stems after mid-term follow *** This study was performed following both the Preferred Reporting Items for Systematic Reviews and Meta-analyses Statement and the Cochrane Handbook for systematic reviews and meta-analysis *** were chosen irrespective of country of origin or language utilized for the article full *** paper included studies that reviewed revision THA for both cemented or uncemented long *** Three eligible studies were included in the *** was conducted by using Review Manager version *** computed the risk ratio as a measure of the treatment effect,taking into account *** used random-effect *** were no significant differences found for intraoperative periprosthetic fractures[risk ratio(RR)=1.25;95%confidence interval(CI):0.29-5.32;P=0.76],aseptic loosening(RR=2.15,95%CI:0.81-5.70;P=0.13),dislocation rate(RR=0.50;95%CI:0.10-2.47;P=0.39),or infection rate(RR=0.99,95%CI:0.82-1.19;P=0.89),between the uncemented and the cemented long stems for revision THA after mid-term *** This study has evaluated the mid-term outcomes of both cemented and uncemented stems at first-time revision *** summary,there were no significant differences in the dislocation rate,aseptic loosening,intraoperative periprosthetic fracture and infection rate between the two cohorts.

关键词： Long stem Cemented Uncemented Revision total hip arthroplasty Meta-analysis

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New Polymer Syntheses Part 60: A Facile Synthetic Route to Polyamides Based on Thieno[2,3-b]thiophene and Their Corrosion Inhibition Behavior

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Chinese Journal of Polymer Science 2018年第7期36卷 835-847页

作者： Kamal I.aly Amr H.Moustafa Essam K.Ahmed hany M.Abd El-lateef Mohamed Gamal Mohamed Sahar M.Mohamed Polymer Research Lab Chemistry Department Faculty of Science Assiut University Chemistry Department Faculty of Science Sohag University Chemistry Department Faculty of Science Minia University Chemistry Department College of Science King Faisal university

Polyamides containing thieno[2,3-b]thiophene moiety were prepared via a simple polycondensation reaction of the diaminothieno[2,3-b]thiophene monomer la with different kinds of diacid chlorides （including oxalyl, adipoyl, sebacoyl, isophthaloyl, terephthaloyl, 4,4＇-azodibenzoyl, 3,3＇-azodibenzoyl, p-phenylene diacryloyl） in the presence of LiC1 and NMP as a solvent through lowtemperature solution polycondensation. The chemical structures of model compound and synthesized polyamides were confirmed by FTIR, nuclear magnetic resonance spectroscopy （including 1 H-NMR and 13 C-NMR） and elemental analysis. In addition, the thermal stability, crystallinity structure and surface morphology of synthesized polyamides were characterized via thermogravametric analysis （TGA）, wide-angle X-ray diffraction analysis （WAXD） and scanning electron microscopy （SEM）. Also, the corrosion inhibition behavior of selected examples ofpolyamides was investigated; the inhibitive effect of the investigated polymers for carbon steel in 1.0 mol＇L-1 HCI was studied using potentiodynamic polarization （PDP） and electrochemical impedance spectroscopy （EIS） methods. PDP results displayed that the polyamides containing thieno[2,3-b]thiophene moiety can be as mixed-type inhibitors. The inhibition efficiency （P, %） was found to be in the range from 67.13% to 96.01%. There is an increase in P by the synthesized polymers in comparison to the starting monomer. The adsorption of these polymers was found to obey Langmuir adsorption isotherm.

关键词： Thieno[2 3-b]thiophene Polymer synthesis Thermal properties Industrial applications Corrosion inhibition

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Acceleration of coasting enhances pregnancy rate in ICSI cycles at risk for ovarian hyperstimulation syndrome

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Journal of Reproduction and Contraception 2016年第2期27卷 103-111页

作者： Ahmed F.Galal Hadeer aly Abbassy Ashraf hany Abd Elrahman Department of Obstetrics and Gynecology Alexandria University Clinical Pathology Department Alexandria University

Objective To assess the efficacy of adding Gn-releasing hormone antagonist（GnR HA） on the day of hC G triggering in a long luteal protocol without withholding the agonist in women who are at a risk to develop ovarian hyperstimulation syndrome（OHSS）.Methods This was a retrospective cohort study conducted upon 50 women who have elevated serum estradiol（E2） level 〉4 500 ng/L at the day of ovum triggering with hC G on a long agonist luteal protocol of controlled ovarian stimulation（COS）. When an exaggerated ovarian response was observed around day 10 of stimulation, immediately the next morning at 6 a.m. gonadotropin administration was stopped or reduced, and a single dose of ganirelix acetate（antagonist） was given sc continuation of the agonist dose hC G. Another serum E2 measurement was done at 6 p.m.（after 12 h of antagonist） then hC G, sc 250 mg and choriogonadotropin α were administered 14 h later after antagonist and documented the reduction of E2 level. Oocyte retrieval was conducted after 34-36 h of hC G administration. The measured outcomes were the level of E2 on the day of hC G injection, number of oocytes and their quality, pregnancy rate and the occurrence of OHSS and its grade in case it *** The total dose for recombinant FSH was 25.3±6.4 ampoules（75 IU/ampoule） while it was 11.0±3.0 ampoules for the urinary hM G. A higher oocyte maturation rate（82.8%） and a high fertilization rate（87.8%） were observed. The mean endometrial thickness was 10.1±1.0 mm on the day of hC G triggering. The higher fertilization rate with the good endometrial thickness observed resulting in a higher pregnancy rate（78.0%, 39/50） with statistically significant（P〈0.05）. A significant reduction of E2 level was documented by a percentage around 40% before hC Ginjection. There were no reported cases of severe or moderate OHSS, however 13 cases（26%） were reported to have mild OHSS *** Acceleration of coasting in cases of OHSS through treatment with GnR HA

关键词： ovarian hyperstimulation syndrome(OHSS) coasting oocyte maturation pregnancy rate

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Plasma D-dimer level in early and late-onset neonatal sepsis

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World Journal of Critical Care Medicine 2022年第3期11卷 139-148页

作者： Mohammed Al-Biltagi Ehab M Hantash Mohammed Ramadan El-Shanshory Enayat aly Badr Mohamed Zahra Manar hany Anwar Department of Pediatrics Faculty of MedicineTanta UniversityTanta 31511AlgharbiaEgypt Department of Pediatrics University Medical CenterArabian Gulf UniversityManama 26671ManamaBahrain Department of Pediatrics University Medical CenterBahrainDr.Sulaiman Al Habib Medical GroupKSAManama 26671ManamaBahrain Department of Anatomy Faculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Neonatology Unit Department of PediatricsDr.Sulaiman Al Habib Medical GroupRiyadh 11636RiyadhSaudi Arabia Department of Pediatrics Hematol UnitTanta UniversityFaculty of MedicineTanta 31511AlgharbiaEgypt Department of Clinical Pathology Faculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Clinical Pathology Ministry of HealthEgyptTanta 31511AlghrabiaEgypt

BACKGROUND Neonatal sepsis is a life-threatening *** diagnosis is essential,but no single marker of infection has been *** activates a coagulation cascade with simultaneous production of the D-dimers due to lysis of *** test reflects the activation of the coagulation *** To assess the D-dimer plasma level,elaborating its clinicopathological value in neonates with early-onset and late-onset neonatal *** The study was a prospective cross-sectional study that included ninety neonates;divided into three groups:Group I:Early-onset sepsis(EOS);Group II:Late-onset sepsis(LOS);and GroupⅢ:Control *** diagnosed neonatal sepsis according to our protocol.C-reactive protein(CRP)and D-dimer assays were compared between EOS and LOS and correlated to the causative microbiological *** D-dimer was significantly higher in septic groups with a considerably higher number of cases with positive *** with LOS had substantially higher levels of D-dimer than EOS,with no significant differences in *** with LOS had a significantly longer hospitalization duration and higher gram-negative bacteriemia and mortality rates than EOS(P<0.01).Gramnegative bacteria have the highest D-dimer levels(Acinetobacter,Klebsiella,and Pseudomonas)and CRP(Serratia,Klebsiella,and Pseudomonas);while gram-positive sepsis was associated with relatively lower levels.D-dimer had a significant negative correlation with hemoglobin level and platelet count;and a significant positive correlation with CRP,hospitalization duration,and mortality *** best-suggested cut-off point for D-dimer in neonatal sepsis was 0.75 mg/L,giving a sensitivity of 72.7%and specificity of 86.7%.The D-dimer assay has specificity and sensitivity comparable to CRP in the current *** The current study revealed a significant diagnostic value for D-dimer in neonatal sepsis.D-dimer can be used as an adjunct to other sepsis markers to increase th

关键词： Early-onset neonatal sepsis Late-onset neonatal sepsis C-reactive protein D-dimer

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