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Incre.sing phosphorus fe.tilize. value.of re.ycle. iron phosphate. by prolonge. flooding and organic matte. addition

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Pe.osphe.e 2024年第3期34卷 631-640页

作者： Roche.le.Joie.SARACANLAO hannah VAN RYCKe. Mie.e.Ve.Be.CK Maarte. e.e.Ae.T e.ik SMOLDe.S Division of Soil and Wate. Manage.e.t Department of Earth and Environmental ScienceKU LeuvenKasteelpark Arenberg 20Heverlee B-3001(Belgium) Soil Se.vice.of Be.gium.Wille. De.Croylaan 48 Leuven 3001(Belgium)

Iron(Fe.mine.als are.commonly use. to re.ove.phosphorus(P)from waste.stre.ms,producing P-loade. Fe.Ⅲ)oxide. or Fe.Ⅱ)phosphate.mine.als(e.g.,vivianite..The.e.mine.als may be.use. as fe.tilize.s to e.hance.P circularity if solubilize. in ***,we.te.te. the.P fe.tilize. value.of re.ycle. Fe.phosphate.(Fe.s)in a pot trial and in an incubation e.pe.ime.t,hypothe.izing that P re.e.se.from Fe.s is possible.unde. Fe.Ⅲ)-re.ucing ***,a pot trial was se. up with rice.Oryza sativa)in all combinations of soil flooding or not,thre. P-de.icie.t soils(acid,ne.tral,and calcare.us),and six Fe.s(thre. Fe.Ⅲ)Ps and thre. Fe.Ⅱ)Ps)re.e.e.ce. to triple.supe.phosphate.TSP)or ze.o *** P uptake.re.ponde. to TSP application in all tre.tme.ts but only marginally to *** re.ox pote.tial did not de.re.se.to-200 mV by flooding for a brie. pe.iod(13 d)during the.pot trial.A longe. incubation e.pe.ime.t(60 d)was pe.forme.,including a tre.tme.t of glutamate.addition to stimulate.re.uctive.conditions,and P availability was asse.se. with CaCl_(2)e.traction of *** addition and/or longe. incubation lowe.e. soil re.ox pote.tial toe.longe. te.m,Fe.Ⅲ)mine.als re.e.se. P,and ade.uate.P was re.che. in the.calcare.us soil and in the.ne.tral soil ame.de. with Fe.Ⅲ)*** can be.conclude. that prolonge. soil flooding and organic matte. addition can e.hance.the.P fe.tilize. e.ficie.cy of ***,application of Fe. in powde. form may e.hance.P availability.

关键词： agronomic e.ficie.cy circular e.onomy P-loade. Fe.Ⅲ)oxide. paddy soil vivianite re.ox

Lipid nanoparticle. de.ive. mRNA to the.blood-brain barrie.

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Nano Re.e.rch 2024年第10期17卷 9126-9134页

作者： Yanina Kuzminich Avraham Shakke. Randi Calkins Se.astian Rudde. Camille.Jone. Je.sie.Doan Bora Jang e.isa Schrade. e.he.e.ri Ryan Ze.hause.n Liming Lian David Loughre. hannah e.Pe.k Rache.le.Wie.e.Dorothy Kove.l Philip J.Santange.o Jame. e.Dahlman Ge.rge.C.Woodruff School of Me.hanical e.gine.ring Georgia Institute of TechnologyAtlantaGA 30332USA Parke. H.Pe.it Institute.for Bioe.gine.ring and Bioscie.ce. Georgia Institute of TechnologyAtlantaGA 30332USA Wallace.H.Coulte. De.artme.t of Biome.ical e.gine.ring Emory University School of Medicine and Georgia Institute of TechnologyAtlantaGA 30332USA

Lipid nanoparticle.(LNPs)have.de.ive.e. RNA to he.atocyte. in patie.ts afte. intrave.ous *** clinical data support e.forts to de.ign LNPs that transfe.t ce.ls in the.ce.tral ne.vous syste.(CNS).Howe.e.,de.ive.y to the.CNS has be.n difficult,in large.part be.ause.quantifying on-targe. de.ive.y alongside.common off-targe. ce.l type. in adult mice.re.ains *** we.re.ort me.hods to isolate.diffe.e.t ce.l type. from the.CNS,and subse.ue.tly pre.e.t mRNA de.ive.y re.douts using a live.-de.arge.e. *** data sugge.t that LNPs without targe.ing ligands can transfe.t ce.e.ral e.dothe.ial ce.ls in mice.afte. intrave.ous *** the.difficulty of crossing the.blood-brain barrie.,the. also unde.score.the.value.of quantifying de.ive.y in the.CNS with ce.l-type.re.olution inste.d of whole.tissue.re.olution.

关键词： lipid nanoparticle mRNA nanome.icine ce.tral ne.vous syste. blood-brain barrie.

Incorporating me.ope.agic fish into the.e.aluation of conse.vation are.s for marine.living re.ource. unde. climate.change.sce.arios

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Marine.Life.Scie.ce.& Te.hnology 2024年第2期6卷 68-83页

作者： Shuhao Liu Yang Liu Katharina Te.chke.Mark AHinde.l Rache. downey Briannyn Woods Bin Kang Shuyang Ma Chi Zhang Jianchao Li Zhe.jiang Ye.Pe.g Sun Jianfe.g He.Yongjun Tian Re.e.rch Ce.tre.for De.p Se. and Polar Fishe.ie. and Key Laboratory of MaricultureMinistry of EducationOcean University of ChinaQingdao 266003China Frontie.s Scie.ce.Ce.te. for De.p Oce.n Multisphe.e. and e.rth Syste. Ocean University of ChinaQingdao 266100China Alfre. We.e.e. Institute Helmholtz Centre for Polar and Marine ResearchAm Handelshafen 1227570 BremerhavenGermany He.mholtz Institute.for Functional Marine.Biodive.sity at the.Unive.sity Olde.burg Ammerländer Heerstraße 23123129 OldenburgGermany Institute.for Marine.and Antarctic Studie. University of TasmaniaHobart 7004Australia Fe.ne. School of e.vironme.t and Socie.y Australian National UniversityCanberraACT 2602Australia Colle.e.of Fishe.ie. Ocean University of ChinaQingdao 266003China Polar Re.e.rch Institute.of China Shanghai 200136China

Me.ope.agic fish(me.o-fish)are.ce.tral spe.ie. within the.Southe.n Oce.n(SO).Howe.e.,the.r e.osyste. role.and adaptive.capacity to climate.change.are.rare.y inte.rate. into prote.te. are.s *** is a pity give. the.r importance.as crucial pre. and pre.ators in food we.s,couple. with the.impacts of climate.***,we.e.timate.the.habitat distribution of nine.me.o-fish using an e.se.ble.mode. approach(MAXe.T,random fore.t,and booste. re.re.sion tre.).Four climate.mode. simulations we.e.use. to proje.t the.r distribution unde. two re.re.e.tative.conce.tration pathways(RCP4.5 and RCP8.5)for short-te.m(2006–2055)and long-te.m(2050–2099)*** addition,we.asse.s the.e.ological re.re.e.tative.e.s of prote.te. are.s unde. climate.change.sce.arios using me.o-fish as indicator *** mode.s show that all spe.ie. shift pole.ard in the.***(family Myctophidae.are.pre.icte. to migrate.pole.ard more.than othe. familie.(Parale.ididae.Notothe.iidae.Bathylagidae.and Gonostomatidae..In comparison,lante.nfishe. we.e.proje.te. to incre.se.habitat are. in the.e.ste.n SO but lose.are. in the.we.te.n SO;the.opposite.was proje.te. for spe.ie. in othe. *** are.s(IAs)of me.o-fish are.mainly distribute. ne.r the.Antarctic Pe.insula and e.st *** prote.te. are. cove. 23% of IAs at pre.e.t and 38%of IAs in the.future.RCP8.5,long-te.m future..Many IAs of me.o-fish still ne.d to be.include. in prote.te. are.s,such as the.Prydz Bay and the.se.s around the.Antarctic *** re.ults provide.a frame.ork for e.aluating prote.te. are.s incorporating climate.change.adaptation strate.ie. for prote.te. are.s manage.e.t.

关键词： Myctophids Me.ope.agic fish Spe.ie. distribution mode. Southe.n Oce.n Antarctic Pe.insula

3-Dime.sional Kine.atic Comparison of Arm Move.e.ts be.we.n an Individual with NGLY1 De.icie.cy and a Ne.rotypical Individual

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Case.Re.orts in Clinical Me.icine 2024年第4期13卷 122-146页

作者： Charle. S. Layne.Christophe. A. Malaya Brock Futre.l Dacia Martine. Diaz Christian Alfaro hannah e. Gustafson Subhalakshmi Chandrase.aran Rhe. M. Phatak Be.nhard Sute. De.artme.t of He.lth and Human Pe.formance University of Houston Houston TX USA Ce.te. for Ne.romotor and Biome.hanics Re.e.rch University of Houston Houston TX USA Ce.te. for Ne.ro e.gine.ring and Cognitive.Scie.ce University of Houston Houston TX USA De.artme.t of Compute. Scie.ce.and e.gine.ring Texas A&M University College Station TX USA Blue.Bird Circle.Re.t Ce.te. Texas Children&#8217s Hospital Houston TX USA Baylor Colle.e.of Me.icine Houston TX USA

NGLY1 De.icie.cy is an ultra-rare.autosomal re.e.sive.y inhe.ite. disorde.. Characte.istic symptoms include.among othe.s, de.e.opme.tal de.ays, move.e.t disorde.s, live. function abnormalitie., se.zure., and proble.s with te.r formation. Move.e.ts are.hype.kine.ic and may include.dysme.ric, chore.-athe.oid, myoclonic and dystonic move.e.t e.e.e.ts. To date. the.e.have.be.n no quantitative.re.orts de.cribing arm move.e.ts of individuals with NGLY1 De.icie.cy. This re.ort provide. quantitative.information about a se.ie. of arm move.e.ts pe.forme. by an individual with NGLY1 De.icie.cy and an age.-matche. ne.rotypical participant. Thre. cate.orie. of arm move.e.ts we.e.te.te.: 1) ope. e.de. re.che. without spe.ific e.d point targe.s;2) goal-dire.te. re.che. that include. grasping an obje.t;3) picking up small obje.ts from a table.place. in front of the.participants. Arm move.e.t kine.atics we.e.obtaine. with a came.a-base. motion analysis syste. and “initiation” and “mainte.ance. phase. we.e.ide.tifie. for e.ch move.e.t. The.combination of the.two phase. was labe.e. as a “comple.e. move.e.t. Thre.-dime.sional analysis te.hnique. we.e.use. to quantify the.move.e.ts and include. hand traje.tory pathle.gth, joint motion are., as we.l as hand traje.tory and joint je.k cost. The.e.te.hnique. we.e.re.uire. to fully characte.ize.the.move.e.ts be.ause.the.NGLY1 individual was unable.to pe.form move.e.ts only in the.primary plane.of progre.sion inste.d producing motion across all thre. plane. of move.e.t. The.individual with NGLY1 De.icie.cy was unable.to pick up obje.ts from a table.or e.fe.tive.y comple.e.move.e.ts re.uiring crossing the.midline. The.succe.sfully comple.e. move.e.ts we.e.analyze. using the.above.te.hnique. and the.re.ults of the.two participants we.e.compare. statistically. Almost all comparisons re.e.le. significant diffe.e.ce. be.we.n the.two participants, with a notable.e.ce.tion of the.3D initiation are. as a pe.ce.tage.of the.comple.e.move.e.t. The.stati

关键词： NGLY1 De.icie.cy De.e.opme.tal Disorde.s Kine.atics 3 Dime.sional Analyse.

Psychophysics of the.hove.fly: cate.orical or continuous color discrimination?

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Curre.t Zoology 2019年第4期65卷 483-492页

作者： Le. hannah Adrian G. Dye. Jair e. Garcia Alan Dorin Martin Burd School of Biological Scie.ce. Monash University Clayton Victoria 3800 Australia Hawke.bury Institute.for the.e.vironme.t Western Sydney University Richmond New South Wales 2753 Australia School of Me.ia and Communication RMIT University Melbourne Victoria 3001 Australia De.artme.t of Physiology Monash University Clayton Victoria 3800 Australia Faculty of Information Te.hnology Monash University Clayton Victoria 3800 Australia

The.e.is incre.sing inte.e.t in flie. as pote.tially important pollinators. Flie. are.known to have.a comple. visual syste., in e.uding 4 spe.tral classe. of photore.e.tors that con tribute.to the.pe.ce.tion of color. Our curre.t unde.standing of how color signals are.pe.ce.ve. by flie. is base. on data for the.blowfly Lucilia sp., which afte. be.ng conditi one. to re.arde. mono chromatic light stimuli, showe. e.ide.e. of a cate.orical color visual syste.. The.re.ulting oppone.t fly color space.has 4 distinct cate.orie., and has be.n use. to inte.pre. how some.fly pollinators may pe.ce.ve.flowe. colors. Howe.e., formal proof that flowe. flie. (Syrphidae. only use.a simple. cate.orical color proce.s re.ains outstanding. In fre.-flying e.pe.ime.ts, we.te.te. the.hove.fly e.istalis te.ax, a Bate.ian mimic of the.hone.be., that re.e.ve. its nutrition by visiting flowe.s. Using a range.of broadband similar-dissimilar color stimuli pre.iously use. to te.t color pe.ce.tion in pollinating hyme.opte.an spe.ie., we.e.aluate. if the.e.are.ste.p change. in be.avioral choice. with continuously incre.sing color diffe.e.ce. as might be.e.pe.te. by cate.orical color proce.sing. Our data re.e.le. that color choice. by the.hove.fly are.me.iate. by a continuous monotonic function. Thus, the.e.flie. did not use.a cate.orical proce.sing, but showe. e.ide.e. of a color discrimination function similar to that obse.ve. in se.e.al be. spe.ie.. We.the.e.ore.e.pirically provide.data for the.minimum color distane. that can be.discriminate. by hove.flie. in fly color space. e.abling an improve. un de.standi ng of plant-poll in ator inte.actions with a non-mode. inse.t spe.ie..

关键词： chromatic signal color mode. floral color fly pollination plant-pollinator vision

Re.e.t advance. in room te.pe.ature.phosphore.ce.ce.of crystalline.boron containing organic compounds

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Aggregate

Aggre.ate 2022年第4期3卷 15-22页

作者： hannah e.Hackne. Dmitrii F.Pe.e.ichka De.artme.t of Che.istry McGill UniversityMontrealQCCanada

In organic compounds,room te.pe.ature.phosphore.ce.ce.RTP)is a rare.ye. highly de.irable.prope.ty that is important for a wide.varie.y of applications,including tissue.imaging,anticounte.fe.ting te.hnologie.,photodynamic the.apy,and organic light-e.itting *** most organic RTP mole.ule. re.y on he.vy atoms or carbonyl functional groups to acce.e.ate.single.-to-triple. inte.syste. crossing,in the.past fe. ye.rs the.e.have.be.n se.e.al re.orts of RTP induce. by boroncontaining functional *** minire.ie. cove.s the.re.e.t lite.ature.on RTP of crystalline.boroorganic compounds and analyze. the.conne.tions be.we.n mole.ular structure.inte.mole.ular inte.actions,and the.re.ulting phosphore.ce.ce.

关键词： lumine.ce.ce organic crystals organoboron che.istry room te.pe.ature.phosphore.ce.ce

Impact of me.hanical bowe. pre.aration in e.e.tive.colore.tal surge.y:A me.a-analysis

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World Journal of Gastroe.te.ology 2018年第4期24卷 519-536页

作者： Katie.e.Rollins hannah Javanmard-e.amghissi Dile.p N Lobo Gastrointe.tinal Surge.y Nottingham Digestive Diseases Centre National Institute of Health Research (NIHR) Nottingham Biomedical Research Centre Nottingham University Hospitals NHS Trust and University of Nottingham Queen’s Medical Centre

AIM To analyse.the.e.fe.t of me.hanical bowe. pre.aration vs no me.hanical bowe. pre.aration on outcome.in patie.ts unde.going e.e.tive.colore.tal *** Me.a-analysis of randomise. controlle. trials and obse.vational studie. comparing adult patie.ts re.e.ving me.hanical bowe. pre.aration with those.re.e.ving no me.hanical bowe. pre.aration, subdivide. into those.re.e.ving a single.re.tal e.e.a and those.who re.e.ve. no pre.aration at all prior to e.e.tive.colore.tal surge.y. Re.ULTS A total of 36 studie.(23 randomise. controlle. trials and 13 obse.vational studie.) including 21568 patie.ts unde.going e.e.tive.colore.tal surge.y we.e.include.. Whe. all studie. we.e.conside.e., me.hanical bowe. pre.aration was not associate. with any significant diffe.e.ce.in anastomotic le.k rate.(OR = 0.90, 95%CI: 0.74 to 1.10, P = 0.32), surgical site.infe.tion(OR = 0.99, 95%CI: 0.80 to 1.24, P = 0.96), intraabdominal colle.tion(OR = 0.86, 95%CI: 0.63 to 1.17, P = 0.34), mortality(OR = 0.85, 95%CI: 0.57 to 1.27, P = 0.43), re.pe.ation(OR = 0.91, 95%CI: 0.75 to 1.12, P = 0.38) or hospital le.gth of stay(ove.all me.n diffe.e.ce.0.11 d, 95%CI:-0.51 to 0.73, P = 0.72), whe. compare. with no me.hanical bowe. pre.aration, nor whe. e.ide.ce.from just randomize. controlle.trials was analyse.. A sub-analysis of me.hanical bowe. pre.aration vs absolute.y no pre.aration or a single.re.tal e.e.a similarly re.e.le. no diffe.e.ce. in clinical outcome.me.sure.. CONCLUSION In the.most compre.e.sive.me.a-analysis of me.hanical bowe. pre.aration in e.e.tive.colore.tal surge.y to date. this study has sugge.te. that the.use.of me.hanical bowe. pre.aration doe. not affe.t the.incide.ce.of postope.ative.complications whe. compare. with no pre.aration. He.ce. me.hanical bowe. pre.aration should not be.administe.e. routine.y prior to e.e.tive.colore.tal surge.y.

关键词： bowe. pre.aration Me.hanical antibiotics morbidity mortality surge.y outcome complications me.a-analysis

Pale.e.ological Re.ponse.of Corals to the.e.d-Triassic Mass e.tinction： An Inte.rational Analysis

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Journal of e.rth Scie.ce 2018年第4期29卷 879-885页

作者： Ge.rge.D Stanle. Jr hannah M e.She.he.d Autumn J Robinson Unive.sity of Montana Pale.ntology Ce.te. Missoula MT 59812 USA

The.e.d-Triassic （also Triassic-Jurassic） mass e.tinction se.e.e.y affe.te. life.on plane. e.rth 200 million ye.rs ago. Pale.climate.change.trigge.e. by the.volcanic e.uptions of the.Ce.tral Atlantic Magmatic Province.（CAMP） cause. a gre.t loss of marine.biodive.sity, among which 96% coral ge.e.a we.e.ge. lost. Howe.e., the.e.is pre.ious little.de.ail on the.pale.e.ology and growth forms lost be.we.n the.late.t Triassic e.tinction and the.e.rly Jurassic re.ove.y. He.e.a ne. pilot study was conducte. by analyzing corallite.inte.ration le.e.s among corals from the.late.t Triassic and e.rly Jurassic time.. Inte.ration le.e.s in corals from the.Late.Triassic and e.rly Jurassic we.e.de.e.mine. through both the.Pale.biology Database.as we.l as from a compre.e.sive.muse.m colle.tion of fossil corals. Re.ults sugge.t that in addition to a major loss of dive.sity following the.e.d-Triassic mass e.tinction, the.e.also was a significant loss of highly inte.rate. corals as cle.rly e.ide.ce. by the.coral data from the.e.rly Jurassic. This confirms our hypothe.is of pale.e.ological se.e.tivity for corals following the.e.d-Triassic mass e.tinction. This study highlights the.importance.of assigning sim- ple.to advance. pale.e.ological characte.s with inte.ration le.e.s, which ope.s a use.ul approach to unde.standing of mass e.tinction and the.dynamics of the.re.ove.y.

关键词： coral loss inte.ration le.e. e.d-Triassic mass e.tinction pale.e.ology

The.CUL4A ubiquitin ligase.is a pote.tial the.ape.tic targe. in skin cance. and othe. malignancie.

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Chine.e.Journal of Cance. 2013年第9期32卷 478-482页

作者： Je.fre. hannah Pe.g-Bo Zhou De.artme.t of Pathology and Laboratory Me.icine Weill Cornell Medical College and Weill Cornell Graduate School of Medical Sciences De.artme.t of Pathology and Laboratory Me.icine Weill Cornell Medical College

Cullin 4A(CUL4A)is an e. ubiquitin ligase.that dire.tly affe.ts DNA re.air and ce.l cycle.progre.sion by targe.ing substrate. including damage.spe.ific DNA-binding prote.n 2(DDB2),xe.ode.ma pigme.tosum comple.e.tation group C(XPC),chromatin lice.sing and DNA re.lication factor 1(Cdt1),and *** work from our laboratory has shown that Cul4a-de.icie.t mice.have.gre.tly re.uce. rate. of ultraviole.-induce. skin *** a ce.lular le.e.,Cul4a-de.icie.t ce.ls have.gre.t capacity for DNA re.air and de.onstrate.a slow rate.of prolife.ation due.primarily to incre.se. e.pre.sion of DDB2 and p21,*** sugge.ts that CUL4A promote. tumorige.e.is(as we.l as accumulation of skin damage.and subse.ue.t pre.ature.aging)by limiting DNA re.air activity and e.pe.iting S phase.*** addition,CUL4A has be.n found to be.up-re.ulate. via ge.e.amplification or ove.e.pre.sion in bre.st cance.s,he.atoce.lular carcinomas,squamous ce.l carcinomas,adre.ocortical carcinomas,childhood me.ulloblastomas,and malignant ple.ral *** of its oncoge.ic activity in skin cance. and up-re.ulation in othe. malignancie.,CUL4A has arise. as a pote.tial candidate.for targe.e. the.ape.tic *** this re.ie.,we.outline.the.e.tablishe. functions of CUL4A and discuss the.e.ligase.s e.e.ge.ce.as a pote.tial drive. of tumorige.e.is.

关键词：泛素连接酶恶性肿瘤皮肤癌治疗 DNA修复 DNA结合蛋白靶点细胞水平