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Foundations of medical decision-making for older adults with cardiovascular disease

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Journal of Geriatric Cardiology 2015年第4期12卷 335-339页

作者： hannah I Lipman Ankur Kalra James N Kirkpatrick Department of Medicine Divisions of Geriatrics and Cardiology Montefiore Medical Center of the Albert Einstein College of Medicine Bronx N~ USA Minneapolis Heart Institute at Abbott Northwestern Hospital Department of Medicine Division of Cardiology Hennepin County Medical Center Minneapo- lis MN USA Cardiovascular Division Department of Medicine University of Pennsylvania' Department of Medical Ethics and Health Policy University of Pennsylvania Philadelphia PA USA

In order to help older adults with cardiovascular disease navigate complex decisions, clinicians must know tenets of medical ethics and have good communication skills. The elements of decision making capacity and informed consent are reviewed, using relevant clinical ex- amples to illustrate the basic concepts. The shared decision making model, by which clinician and patient work together to determine the plan of care, is described. Useful communication techniques to implement shared decision making are suggested.

关键词： Cardiovascular disease Medical decision-making Older adults

Recent advances in room temperature phosphorescence of crystalline boron containing organic compounds

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Aggregate 2022年第4期3卷 15-22页

作者： hannah E.Hackney Dmitrii F.Perepichka Department of Chemistry McGill UniversityMontrealQCCanada

In organic compounds,room temperature phosphorescence(RTP)is a rare,yet highly desirable,property that is important for a wide variety of applications,including tissue imaging,anticounterfeiting technologies,photodynamic therapy,and organic light-emitting *** most organic RTP molecules rely on heavy atoms or carbonyl functional groups to accelerate singlet-to-triplet intersystem crossing,in the past few years there have been several reports of RTP induced by boroncontaining functional *** minireview covers the recent literature on RTP of crystalline boroorganic compounds and analyzes the connections between molecular structure,intermolecular interactions,and the resulting phosphorescence.

关键词： luminescence organic crystals organoboron chemistry room temperature phosphorescence

Comparative Analysis of Vaccine Inequity and COVID-19 Transmission Amid the Omicron Variant Among Countries--Six Countries,Asia-Pacific Region,2022

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China CDC weekly 2023年第33期5卷 731-736,I0001-I0006页

作者： Jingli Yang hannah McClymont David JWarne Liping Wang Wenbiao Hu School of Public Health and Social Work Queensland University of TechnologyBrisbaneAustralia College of Earth and Environmental Sciences Lanzhou UniversityLanzhou CityGansu ProvinceChina School of Mathematical Sciences Queensland University of TechnologyBrisbaneAustralia Centre for Data Science Queensland University of TechnologyBrisbaneAustralia Division of Infectious Diseases Chinese Center for Diseases Control and PreventionBeijingChina.

What is already known about this topic?The coronavirus disease 2019(COVID-19)persists as a significant global public health *** predominant strain,severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),notably the Omicron variant,continues to undergo *** vaccination is heralded as the paramount solution to cease the pandemic,challenges persist in providing equitable access to COVID-19 *** is added by this report?The distribution of vaccine coverage exhibited disparities between high-income and middle-income countries,with middle-income countries evidencing lower levels of *** data further suggested that countries with lesser vaccination levels tended to display a higher case fatality *** indicated that an increase in population-wide vaccination was effective in mitigating COVID-19 related *** are the implications for public health practice?The findings of this research underscore the pressing necessity for equitable access to vaccines to effectively mitigate the COVID-19 pandemic within the Asia-Pacific region.

关键词： COV income vaccination

Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation

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Translational Neurodegeneration 2020年第2期9卷 248-269页

作者： Luodan Yang hannah Youngblood Chongyun Wu Quanguang Zhang Department of Neuroscience and Regenerative Medicine Medical College of GeorgiaAugusta University112015th StreetAugustaGA30912USA Department of Cellular Biology and Anatomy Medical College of GeorgiaAugusta University112015th StreetAugustaGA30912USA

Mitochondrial dysfunction plays a central role in the formation of neuroinflammation and oxidative stress,which are important factors contributing to the development of brain *** evidence suggests mitochondria are a promising target for ***,methods targeting mitochondria have been considered as potential approaches for treatment of brain disease through the inhibition of inflammation and oxidative *** review will discuss two widely studied approaches for the improvement of brain mitochondrial respiration,methylene blue(MB)and photobiomodulation(PBM).MB is a widely studied drug with potential beneficial effects in animal models of brain disease,as well as limited human ***,PBM is a non-invasive treatment that promotes energy production and reduces both oxidative stress and inflammation,and has garnered increasing attention in recent *** and PBM have similar beneficial effects on mitochondrial function,oxidative damage,inflammation,and subsequent behavioral ***,the mechanisms underlying the energy enhancing,antioxidant,and anti-inflammatory effects of MB and PBM *** review will focus on mitochondrial dysfunction in several different brain diseases and the pathological improvements following MB and PBM treatment.

关键词： Mitochondrial dysfunction Neuroprotection Methylene blue Photobiomodulation

A critical literature review of bioretention research for stormwater management in cold climate and future research recommendations

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Frontiers of Environmental Science & Engineering 2017年第4期11卷 23-37页

作者： hannah Kratky Zhan Li Yijun Chen Chengjin Wang Xiangfei Li Tong Yu Department of Civil and Environmental Engineering University of Alberta Edmonton Alberta T6G 1H9 Canada City Planning City of Edmonton Edmonton Alberta T5J 0J4 Canada

Bioretention is a popular best management practice of low impact development that el/ecUvely restores urban hydrologic characteristics to those ofpredevelopment and improves water quality prior to conveyance to surface waters. This is achieved by utilizing an engineered system containing a surface layer of mulch, a thick soil media often amended with a variety of materials to improve water oualitv, a variety of vegetation, and underdrains, depending on the surrounding soil *** systems have been studied quite extensively for warm climate applications, but ctata strongly supporting their long-tema efficacy and application in cold climates is sparse. Although it is apparent that biorelention is an effective stormwater management system, its design in cold climate needs further research. Existing cold climate research has shown that coarser media is required to prevent concrete frost from forming. For spring, summer and fall seasons, if sufficient permeability exists to drain the system prior to freezing, peak flow and volume reduction can be maintained. Additionally. contaminants that are removed via filtration are also not impacted by cold climates. In contrary, dissolved contaminants, nutrients, and organics are significantly more variable in their ability to be removed or degraded via bioretention in colder temperatures. Winter road maintenance salts have been shown to negatively impact the removal of some contaminants and positively impact others, while their effects on properly selected vegetation or bacteria health are also not well understood. Research in these water quality aspects has been inconsistent and therefore requires further study.

关键词： Bioretention Cold climate Low impact development Stormwater

Impact of mechanical bowel preparation in elective colorectal surgery:A meta-analysis

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World Journal of Gastroenterology 2018年第4期24卷 519-536页

作者： Katie E Rollins hannah Javanmard-Emamghissi Dileep N Lobo Gastrointestinal Surgery Nottingham Digestive Diseases Centre National Institute of Health Research (NIHR) Nottingham Biomedical Research Centre Nottingham University Hospitals NHS Trust and University of Nottingham Queen’s Medical Centre

AIM To analyse the effect of mechanical bowel preparation vs no mechanical bowel preparation on outcome in patients undergoing elective colorectal *** Meta-analysis of randomised controlled trials and observational studies comparing adult patients receiving mechanical bowel preparation with those receiving no mechanical bowel preparation, subdivided into those receiving a single rectal enema and those who received no preparation at all prior to elective colorectal surgery. RESULTS A total of 36 studies(23 randomised controlled trials and 13 observational studies) including 21568 patients undergoing elective colorectal surgery were included. When all studies were considered, mechanical bowel preparation was not associated with any significant difference in anastomotic leak rates(OR = 0.90, 95%CI: 0.74 to 1.10, P = 0.32), surgical site infection(OR = 0.99, 95%CI: 0.80 to 1.24, P = 0.96), intraabdominal collection(OR = 0.86, 95%CI: 0.63 to 1.17, P = 0.34), mortality(OR = 0.85, 95%CI: 0.57 to 1.27, P = 0.43), reoperation(OR = 0.91, 95%CI: 0.75 to 1.12, P = 0.38) or hospital length of stay(overall mean difference 0.11 d, 95%CI:-0.51 to 0.73, P = 0.72), when compared with no mechanical bowel preparation, nor when evidence from just randomized controlledtrials was analysed. A sub-analysis of mechanical bowel preparation vs absolutely no preparation or a single rectal enema similarly revealed no differences in clinical outcome measures. CONCLUSION In the most comprehensive meta-analysis of mechanical bowel preparation in elective colorectal surgery to date, this study has suggested that the use of mechanical bowel preparation does not affect the incidence of postoperative complications when compared with no preparation. Hence, mechanical bowel preparation should not be administered routinely prior to elective colorectal surgery.

关键词： bowel preparation Mechanical antibiotics morbidity mortality surgery outcome complications meta-analysis

Changes of water chemistry from rainfall to stream flow in Obagbile Catchment, Southwest Nigeria

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Regional Sustainability 2022年第2期3卷 170-181页

作者： Mojisola hannah OMOGBEHIN Isaac Ayo OLUWATIMILEHIN Department of Geography Obafemi Awolowo UniversityIle Ife220101Nigeria

Water chemistry changes when it flows through different *** study aims to characterize the differences of water(including rainwater,overland flow,soil water,groundwater,and stream water)chemistry of five kinds of water in Obagbile Catchment in Southwest Nigeria,determine the changes in water chemistry that occur as the water moves from one pathway to another,and identify the factors responsible for the water chemistry *** do these,we collected 50 water samples from 10 heavy storms that received equal to or more than 10 mm of rain within an hour to test the changes of water chemical properties across various pathways in this *** results show that overland flow had the highest p H and electrical conductivity(EC)and rainwater had the lowest values of the two ***^(2+),Mg^(2+),Cl^(ˉ),and HCOO^(ˉ) were found to have their highest concentrations in stream water;meanwhile,NO_(3)^(–),NH_(4)^(+),and SO_(4)^(2–) were found to have almost the same low concentrations in all the water samples.K+was only dominant in stream water;while dissolved organic carbon(DOC)was lowest in rainwater,same in overland flow,soil water,and groundwater samples,and highest in stream *** component analysis(PCA)showed that for all the water samples from different pathways,two factors mainly accounted for the total *** two factors were related to the crustal and anthropogenic sources in rainwater,suggesting that the high loadings of major cations(e.g.,Ca^(2+) and Mg^(2+)) in rainwater samples are *** PCA for the overland flow and soil water showed strong correlations among pH,EC,and the concentrations of Na^(+),Mg^(2+),HCOO^(-),and CH_(3)COO^(-),while the high loadings of all the parameters and the strong correlations among each other were evident in the stream *** conclusion,the chemical constituents found in water are also the components of pathways through which the water *** major factors responsible for the change in the

关键词： Water chemistry Rainwater Overland flow Soil water Obagbile Catchment Principal component analysis

Tattoos as a window to the psyche:How talking about skin art can inform psychiatric practice

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World Journal of Psychiatry 2017年第3期7卷 148-158页

作者： hannah Roggenkamp Andrew Nicholls Joseph M Pierre Mental Illness Research Education and Clinical CenterVA Puget Sound Healthcare System VA Greater Los Angeles Healthcare System Department of Psychiatry and Biobehavioral Sciences David Geffen School of Medicine at UCLA

Tattooing the skin as a means of personal expression is a ritualized practice that has been around for centuries across many different ***,the symbolic meaning of tattoos has evolved over time and is highly individualized,from both the internal perspective of the wearer and the external perspective of an *** modern Western societies through the 1970 s,tattoos represented a cultural taboo,typically associated with those outside of the mainstream such as soldiers,incarcerated criminals,gang members,and others belonging to marginalized and counter-cultural *** paper aims to review the more recent epidemiology of tattoos in Western culture in order to establish that tattooing has become a mainstream *** then review psychological and psychiatric aspects of tattoos,with a goal of revising outmoded stigmas about tattooing and helping clinicians working with tattooed patients to facilitate an exploration of the personal meaning of skin art and *** suggest that as a kind of augmentation of the physical exam,looking at and talking to patients about their tattoos can provide a valuable window into the psyche,informing clinical practice.

关键词： Tattoos Military psychiatry Deviance Skin art Psychopathology Psychology

Epidemic Features of COVID-19 and Potential Impact of Hospital Strain During the Omicron Wave—Australia,2022

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China CDC weekly 2023年第7期5卷 165-169,I0001-I0006页

作者： Jingli Yang hannah McClymont Liping Wang Sotiris Vardoulakis Wenbiao Hu School of Public Health and Social Work Queensland University of TechnologyBrisbaneAustralia College of Earth and Environmental Sciences Lanzhou UniversityLanzhou CityGansu ProvinceChina Division of Infectious Diseases Chinese Center for Diseases Control and PreventionBeijing MunicipalityChina National Centre for Epidemiology and Population Health College of Health and MedicineThe Australian National UniversityCanberraAustralia Healthy Environments And Lives(HEAL)National Research Network Australia

Summary What is already known about this topic?Hospitals have experienced a surge in admissions due to the increasing number of Omicron *** the epidemiological features of coronavirus disease 2019(COVID-19)and the strain it places on hospitals will provide scientific evidence to help policymakers better prepare for and respond to future *** is added by this report?The case fatality rate of COVID-19 was 1.4 per 1,000 persons during the Omicron wave.

关键词： Impact COV policy