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Nano Research 2022年第10期15卷 9368-9376页

作者： Kai Li Ying Ye Wenchao Zhang Yao Zhou Yudong Zhang Shisheng lin hang lin Jian Ruan Chao Liu State Key Laboratory of Silicate Materials for Architectures(SMART) Wuhan University of Technology122 Luoshi RoadHongshanWuhan 430070China CAS Key Laboratory of Optoelectronic Materials Chemistry and Physics Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China Fujian Science&Technology Innovation Laboratory for Optoelectronic Information of China Fuzhou 350108China

All inorganic CsPbX_(3)(X=Cl,Br,and I)perovskite nanocrystals have made unprecedented radical progresses for opto-electronic applications,but their instability and toxicity of lead impede their wide applications.Herein,we report the first precipitation of leadfree Mn:Cs_(2)ZnX_(4) nanocrystals in glasses.Efficient green and red photoluminescence are realized from these Mn:Cs_(2)ZnX_(4 )nanocrystals in glasses.By adjusting the size and halide component in these nanocrystals,coordination environment of Mn^(2+)ions can be tuned,leading to tunable photoluminescence with improved quantum efficiency.It is illustrated that in-situ precipitation of these Mn:Cs_(2)ZnX_(4) nanocrystals in glasses significantly improves their thermal-,chemical-,and photo-stabilities,making them promising for light-emitting diodes with stable chromaticity coordinates.

关键词： cesium zinc halides nanocrystals lead-free long-term-stability light-emitting diode(LED)

Patterned glass ceramic design for high-brightness high-color-quality laser-driven lightings

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Journal of Advanced Ceramics 2022年第6期11卷 862-873页

作者： Qiugui HUANG hang lin Bo WANG Shisheng lin Pengfei WANG Ping SUI Ju XU Yao CHENG Yuansheng WANG Key Laboratory of Optoelectronic Materials Chemistry and Physics Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China College of Chemistry and Materials Science Fujian Normal UniversityFuzhou 350007China Fujian Science&Technology Innovation Laboratory for Optoelectronic Information of China Fuzhou 350108China School of Applied Physics and Materials Wuyi UniversityJiangmen 529020China

Up-to-date laser-driven lightings confront a challenge of simultaneously achieving good photometric and chromatic performances.Herein,the coupling of“patterned package design”and“phosphor wheel”was proposed and demonstrated effectively to deal with this tough issue,based on a new architecture of CaAlSiN3:Eu2+(CASN:Eu)glass ceramic film(GCF)on Y_(3)Al_(5)O_(12):Ce^(3+)(YAG:Ce)GC plate.The fabricated composite has no interface between the two functional layers and retains the admirable luminescent features from CASN:Eu and YAG:Ce for the microstructural integrity during co-sintering.The studies on laser-microcrystalline interactions reveal that the luminescence saturation is almost determined by thermal quenching for YAG:Ce,but is ascribed to thermal/intensity quenching which are equally crucial for CASN:Eu.Benefiting from the elaborate architecture design,good color chromaticity tunability was obtained,and severe photon reabsorption was reduced.Moreover,accompanied with the rotation induced increase of thermal convection to air and pulse-like excitation,the constructed lighting engine under blue laser driven shows bright white light with luminous flux(LF)higher than 1000 lm,adjustable chromaticity from cool to warm,and improved color rendering index(CRI)approaching to 70.

关键词： laser lightings glass ceramics(GCs) white light garnets nitrides

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中国特色西方音乐研究的对话性

音乐艺术（上海音乐学院学报） 2024年第2期 50-58页

作者：林杭福建师范大学中国特色西方音乐研究中心福州350108

中国特色西方音乐研究在坚守中华优秀传统文化的立场下,依托巴赫金对话主义的理论主张,具有丰富的对话性。中国的西方音乐研究作为一种“异文化”研究,其互动思维的建立不仅需要深潜于涵义层的对话,而且更需要关注现实,最终在充满对话... 详细信息

中国特色西方音乐研究在坚守中华优秀传统文化的立场下,依托巴赫金对话主义的理论主张,具有丰富的对话性。中国的西方音乐研究作为一种“异文化”研究,其互动思维的建立不仅需要深潜于涵义层的对话,而且更需要关注现实,最终在充满对话性的形塑中彰显其主体立场与话语力量。

关键词：西方音乐巴赫金中国特色对话性

Transplantation of adult spinal cord tissue: Transection spinal cord repair and potential clinical translation

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Science China(Life Sciences) 2019年第6期62卷 870-872页

作者： hang lin Center for Cellular and Molecular Engineering Department of Orthopaedic Surgery University of Pittsburgh School of Medicine McGowan Institute for Regenerative Medicine University of Pittsburgh School of Medicine

Spinal cord injury (SCI), often resulting from car accidents,falls and violence, represents a complicated trauma affecting multiple tissues, such as the vertebrate, disks of the spinal column, or the spinal cord itself. Direct injury to the spinal cord, which is the focus of this insight, may disrupt the neuronal connections between the brain and the periphery,leading to the loss of motor function and paralysis. Consequently, SCI patients suffer neurologic deficits and disability,and are subjected to high healthcare costs for a lifetime.

关键词： Spinal cord injury car accidents costs for a lifetime

Mechanotransduction pathways in articular chondrocytes and the emerging role of estrogen receptor-α

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骨研究:英文版 2023年第2期11卷 229-247页

作者： Ning Wang Yangfan Lu Benjamin B.Rothrauff Aojie Zheng Alexander Lamb Youzhen Yan Katelyn E.Lipa Guanghua Lei hang lin Department of Orthopaedic Surgery Xiangya HospitalCentral South UniversityChangsha 410008 HunanChina Department of Orthopaedic Surgery University of Pittsburgh School of MedicinePittsburghPA15219USA Department of Bioengineering University of Pittsburgh Swanson School of EngineeringPittsburghPA15219USA and Mc Gowan Institute for Regenerative Medicine University of Pittsburgh School of MedicinePittsburghPA15219USA

In the synovial joint,mechanical force creates an important signal that influences chondrocyte behavior.The conversion of mechanical signals into biochemical cues relies on different elements in mechanotransduction pathways and culminates in changes in chondrocyte phenotype and extracellular matrix composition/structure.Recently,several mechanosensors,the first responders to mechanical force,have been discovered.However,we still have limited knowledge about the downstream molecules that enact alterations in the gene expression profile during mechanotransduction signaling.Recently,estrogen receptorα(ERα)has been shown to modulate the chondrocyte response to mechanical loading through a ligand-independent mechanism,in line with previous research showing that ERαexerts important mechanotransduction effects on other cell types,such as osteoblasts.In consideration of these recent discoveries,the goal of this review is to position ERαinto the mechanotransduction pathways known to date.Specifically,we first summarize our most recent understanding of the mechanotransduction pathways in chondrocytes on the basis of three categories of actors,namely mechanosensors,mechanotransducers,and mechanoimpactors.Then,the specific roles played by ERαin mediating the chondrocyte response to mechanical loading are discussed,and the potential interactions of ERαwith other molecules in mechanotransduction pathways are explored.Finally,we propose several future research directions that may advance our understanding of the roles played by ERαin mediating biomechanical cues under physiological and pathological conditions.

关键词： structure loading directions

Strength and failure characteristics of brittle jointed rock-like specimens under uniaxial compression:Digital speckle technology and a particle mechanics approach

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International Journal of Mining Science and Technology 2018年第4期28卷 662-670页

作者： Rihong Cao hang lin Ping Cao School of Resources and Safety Engineering Central South University State Key Laboratory for Geo Mechanics and Deep Underground Engineering China University of Mining & Technology

The strength and failure characteristics of most natural rock mass are influenced by discontinues such as fissures, joints, and weak surfaces. In the present study, the strength and failure behavior of ubiquitousjoint rock-like specimens under uniaxial loading have been investigated by DIC(digital image correlation) and discrete element numerical method(PFC2 D). The results are obtained. Firstly, the UCSJof specimens with c = 15° or 30° shows similar tendency while a goes from 0° to 75°. With c = 45° or 60°, the UCSJof specimens increases when a goes from 0° to 30° and decreases after a goes beyond 30°. With c = 75°, the peak UCSJvalue is reached when a = 0°. The UCSJvalue shows an increasing trend when a goes from 60° to 75°. Secondly, the ubiquitous-joint specimens present different failure modes for various levels of a and c(b-a). Based on the experimental results, the failure mode of ubiquitous-joint specimens can be classified into three categories: stepped path failure, failure through parallel plane, and failure through cross plane.

关键词：标本粒子力学特征单轴技术点缀岩石连接

Engineering osteoarthritic cartilage model through differentiating senescent human mesenchymal stem cells for testing disease-modifying drugs

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Science China(Life Sciences) 2022年第2期65卷 309-327页

作者： Ning Wang Yuchen He Silvia Liu Meagan J.Makarcyzk Guanghua Lei Alexander Chang Peter G Alexander Tingjun Hao Anne-Marie Padget Nuria de Pedro Tsapekos Menelaos hang lin Department of Orthopaedic Surgery University of Pittsburgh School of MedicinePittsburgh PA 15219USA Department of Orthopedic Surgery Xiangya HospitalCentral South UniversityChangsha 410008China Department of Pathology University of Pittsburgh School of MedicinePittsburgh PA 15219USA Department of Bioengineering University of Pittsburgh Swanson School of EngineeringPittsburgh PA 15219USA Department of Bioinformatics University of Pittsburgh School of MedicinePittsburgh PA 15219USA McGowan Institute for Regenerative Medicine University of Pittsburgh School of MedicinePittsburgh PA 15219USA Department of Biology University of Pittsburgh Dietrich School of Arts and SciencePittsburgh PA 15219USA Department of Research B2B Life Length SLMadrid 28010Spain Xiangya Third Hospital Central South UniversityChangsha 410013China

Significant cellular senescence has been observed in cartilage harvested from patients with osteoarthritis(OA).In this study,we aim to develop a senescence-relevant OA-like cartilage model for developing disease-modifying OA drugs(DMOADs).Spe-cifically,human bone marrow-derived mesenchymal stromal cells(MSCs)were expanded in vitro up to passage 10(P10-MSCs).Following their senescent phenotype formation,P10-MSCs were subjected to pellet culture in chondrogenic medium.Results from qRT-PCR,histology,and immunostaining indicated that cartilage generated from P10-MSCs displayed both senescent and OA-like phenotypes without using other OA-inducing agents,when compared to that from normal passage 4(P4)-MSCs.Interestingly,the same gene expression differences observed between P4-MSCs and P10-MSC-derived cartilage tissues were also observed between the preserved and damaged OA cartilage regions taken from human samples,as demonstrated by RNA sequencing data and other analysis methods.Lastly,the utility of this senescence-initiated OA-like cartilage model in drug development was assessed by testing several potential DMOADs and senolytics.The results suggest that pre-existing cellular senescence can induce the generation of OA-like changes in cartilage.The P4-and P10-MSCs derived cartilage models also represent a novel platform for predicting the efficacy and toxicity of potential DMOADs on both preserved and damaged cartilage in humans.

关键词： osteoarthritis MSC senescence cartilage tissue engineering disease-modifying OA drug senolytic

High-security-level multi-dimensional optical storage medium:nanostructured glass embedded with LiGa_(5)O_(8):Mn^(2+) with photostimulated luminescence

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Light(Science & Applications) 2020年第1期9卷 1799-1808页

作者： Shisheng lin hang lin Chonggeng Ma Yao Cheng Sizhe Ye Fulin lin Renfu Li Ju Xu Yuansheng Wang Key Laboratory of Optoelectronic Materials Chemistry and Physics Key Laboratory of Design and Assembly of Functional NanostructuresFujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhouFujian 350002China University of Chinese Academy of Sciences Beijing 100049China CQUPT-BRU Innovation Institute Chongqing University of Posts and TelecommunicationsChongqing 400065China Xiamen Institute of Rare-earth Materials Haixi InstitutesChinese Academy of SciencesXiamenFujian 361000China

The launch of the big data era puts forward challenges for information preservation technology,both in storage capacity and security.Herein,a brand new optical storage medium,transparent glass ceramic(TGC)embedded with photostimulated LiGa5O8:Mn2+nanocrystals,capable of achieving bit-by-bit optical data write-in and read-out in a photon trapping/detrapping mode,is developed.The highly ordered nanostructure enables light–matter interaction with high encoding/decoding resolution and low bit error rate.Importantly,going beyond traditional 2D optical storage,the high transparency of the studied bulk medium makes 3D volumetric optical data storage(ODS)possible,which brings about the merits of expanded storage capacity and improved information security.Demonstration application confirmed the erasable-rewritable 3D storage of binary data and display items in TGC with intensity/wavelength multiplexing.The present work highlights a great leap in photostimulated material for ODS application and hopefully stimulates the development of new multi-dimensional ODS media.

关键词： optical glass trapping

Optimal Gestational Weight Gain for Women with Gestational Diabetes Mellitus—China,2011–2021

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China CDC weekly 2023年第9期5卷 189-193,I0001-I0007页

作者： Jinlang Lyu Yin Sun Yuelong Ji Nana Liu Suhan Zhang hang lin Yaxin Wang Xuanjin Yang Shuai Ma Na Han Yang Mi Dan Zheng Zhifen Yang Hongping Zhang Yan Jiang Liangkun Ma Haijun Wang School of Public Health Peking UniversityBeijing MunicipalityChina Peking Union Medical College Hospital Beijing MunicipalityChina Chinese Academy of Medical Sciences and Peking Union Medical College Beijing MunicipalityChina Tongzhou Maternal and Child Health Hospital Beijing MunicipalityChina Northwest Women’s and Children’s Hospital Xi'an CityShaanxi ProvinceChina Guiyang Maternal and Child Health Hospital Guiyang CityGuizhou ProvinceChina The Fourth Hospital of Hebei Medical University Shijiazhuang CityHebei ProvinceChina Wenzhou People’s Hospital Wenzhou CityZhejiang ProvinceChina People’s Hospital of Dong’e County Liaocheng CityShandong ProvinceChina.

Summary What is already known about this topic?Joint effects of gestational weight gain(GWG)and hyperglycemia on adverse pregnancy outcomes suggest that lower optimal GWG is optimal for women with gestational diabetes mellitus(GDM).However,there is still a lack of guidelines.What is added by this report?Optimal weekly GWG range after diagnosis of GDM for underweight,normal-weight,overweight,and obese women was 0.37–0.56 kg/week,0.26–0.48 kg/week,0.19–0.32 kg/week,and 0.12–0.23 kg/week,respectively.What are the implications for public health practice?The findings may be used to inform prenatal counseling regarding optimal gestational weight gain for women with gestational diabetes mellitus,and suggest the need for weight gain management.

关键词： diagnosis gestational pregnancy

Sorption and desorption of sex hormones in soil-and sediment-water systems:A review

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Soil Ecology Letters 2022年第1期4卷 1-17页

作者： Xiong Dai Xingjian Yang Bihai Xie Jiajia Jiao Xiuping Jiang Chengyu Chen Zhen Zhang Zhili He hang lin Weisong Chen Yongtao Li College of Natural Resources and Environment Joint Institute for Environment&EducationSouth China Agricultural UniversityGuangzhou 510642China Key Laboratory of Southern Farmland Pollution Prevention and Control Ministry of Agriculture and Rural AffairsHunan Division of GRG Metrology and TestChangsha 410000China Dongguan Institute of Food Crops and Flowers Dongguan 523063China

Sex hormones are a group of potent endocrine disruptors that can be released into agricultural soils and sediment via wastewater discharge and manure fertilization.Sorption represents a critical determinant for the transport potential and risks of sex hormones in the environment.Therefore,this study reviewed the sorption and desorption mechanisms of sex hormones in soil-and sedimentwater systems,and summarized the effects of various factors on sorption and desorption processes.A total of 359 set of sorption data were collected from the literature.Sex hormones were mostly described by the linear model.The sorption magnitudes(logKoc)of estrogens,androgens,and progestins were in the range of 2.77–3.90,2.55–4.18,and 2.61–4.39,respectively.The average logKoc values of the sex hormones were significantly correlated with their logKow values(R^(2)=0.13,p<0.05),while the R^(2) values were much lower than those when fewer sex hormones were included for analysis.In addition,the Kd values of most sex hormones were significantly correlated with the OC%of soils and sediment(R^(2)=0.16–0.99,p<0.05),but were insignificantly correlated with the particle size distribution and surface area.These results indicated that hydrophobic partitioning interaction and other specific interactions are responsible for sex hormone uptake in soil-and sediment-water systems.The sorption of sex hormones in soil-and sediment-water systems can also be affected by other environmental variables,including pH,temperature,and ionic strength.Future studies should focus on the coupled leaching-sorption processes in manure-water-soil systems under field-scale conditions.

关键词： Endocrine disruption Environmental variable Soil organic matter Mineral Desorption hysteresis