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Incidence of toxoplasmosis in patients with cirrhosis

World Journal of Gastroenterology 2004年第3期10卷 452-454页

作者： Sebnem Ustun Umit Aksoy hande dagci Galip Ersoz Department of Gastroenterology School of MedicineUniversity of Ege35100 BornovaIzmirTurkey Department of Parasitology School of MedicineUniversity of Dokuz EylulIzmirTurkey Department of Parasitology School of MedicineUniversity of EgeIzmirTurkey Department of Gastroenterology School of MedicineUniversity of EgeIzmirTurkey

AIM:It is known that toxoplasmosis rarely leads to various liver pathologies,most common of which is granulomatose hepatitis in patients having normal immune *** who have cirrhosis of the liver are subject to a variety of cellular as well as humoral immunity ***,it may be considered that toxoplasmosis can cause more frequent and more severe diseases in patients with cirrhosis and is capable of changing the course of the *** aim of this study was to investigate the frequency of toxoplasmosis in patients with cirrhosis. METHODS:Serum samples were taken from 108 patients with cirrhosis under observation in the Hepatology Polyclinic of the Gastroenterology Clinic,and a control group made up of 50 healthy blood *** and ELISA methods were used to investigate the IgG and IgM antibodies,which had developed from these sera. RESULTS:Toxoplasma IgG and IgN antibody positivity was found in 74 (68.5%) of the 108 cirrhotic patients and 24 (48%) of the 50 people in the control *** difference between them was significant (P<0.05). CONCLUSION:In conclusion,it was found that the toxopiasma sero-prevalence in the cirrhotic patients in this study was *** patients are likely to form a toxoplasma risk *** detailed studies are needed on this subject.

关键词： Adult Animals Antibodies, Protozoan Female Humans Incidence Liver Cirrhosis Male Middle Aged Toxoplasma Toxoplasmosis

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Effects of Cd^(+2),Cu^(+2),Ba^(+2) and Co^(+2) ions on Entamoeba histolytica cysts

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World Journal of Gastroenterology 2004年第3期10卷 449-451页

作者： Umit Aksoy Sebnem Ustun hande dagci Süleyman Yazar Department Department of Gastroenterology Medical FacultyEge UniversityBornovaZzmir-Turkey Department of Parasitology Medical FacultyEge UniversityBornovaZzmir-Turkey Department of Parasitology Medical FacultyErciyes UniversityKayseri-Turkey

AIM:The effects of cobalt,copper,cadmium and barium ions on the cysts of Entamoeba histolyt/ca (E,histolytica), an amebic dysentery agent,cultured in Robinson medium were investigated. METHODS:*** cysts and trophozoites isolated from a patient with amebiasis were cultivated in the medium, incubated at 37℃ for a period of 4 days and 40×10~4/ml amebic cysts were then transferred to a fresh *** the second stage,0.05,0.1 and 0.2 mM of selected metal ions were added to the medium,and the effects of these ions on parasitic reproduction compared with the control group were observed. RESULTS:It was determined that the number of living parasites in all the groups containing metal ions decreased significantly starting from 30 minutes (P<0.01).CuCl_2 showed the highest lethal effect on *** cysts,whereas the lowest lethal effect was observed with CoCl_*** was also seen that the number of living cells was decreased as the ion concentration and exposure time were increased,and that there were no living parasites in the medium at the end of 24 h (P<0.01). CONCLUSION:It may be stated that the effect of ever- increasing contamination of the environment with metal waste materials on parasites should be investigated further.

关键词： Animals Barium Cadmium Cobalt Copper Entamoeba histolytica Entamoebiasis Humans Ions

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Prevalence of amebiasis in inflammatory bowel disease in Turkey

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World Journal of Gastroenterology 2003年第8期9卷 1834-1835页

作者： Sebnem Ustun hande dagci Umit Aksoy Yuksel Guruz Galip Ersoz Department of Gastroenterology School of MedicineUniversity of Ege35100BornovaIzmirTurkey Department of Parasitology School of MedicineUniversity of Ege35100BornovaIzmirTurkey Department of Parasitology School of MedicineUniversity of Dokuz EylulIzmirTurkey

AIM: To explore the prevalence of amebiasis in inflammatory bowel disease (IBD) in ***: In this study, amoeba prevalence in 160 cases of IBD, 130 of ulcerative colitis and 30 of Crohn′s disease were investigated in fresh faeces by means of wet mount+Lugol′s iodine staining, modified formol ethyl acetate and trichrome staining methods and to compare the diagnostic accuracy of wet mount+Lugol′s iodine staining,modified formol ethyl acetate and trichrome staining methods in the diagnosis of Entamoeba histolytica (E. histolytica)/Entamoeba dispar (E. dispar).RESULTS: E. histolytica/E. dispar cysts and trophozoites were found in 14 (8.75 %) of a total of 160 cases, 13 (10.0 %)of the 130 patients with ulcerative colitis and 1 (3.3 %) of the 30 patients with Crohn′s disease. As for the 105 patients in the control group who had not any gastrointestinal complaints, 2 (1.90 %) patients were found to have ***/E. dispar cysts in their faeces. Parasite prevalence in the patient group was determined to be significantly higher than that in the control group (Fischer′s Exact Test, P＜0.05).When the three methods of determining parasites were compared with one another, the most effective one was found to be trichrome staining method (Kruskal-Wallis Test, P＜0.01).CONCLUSION: Consequently, amoeba infections in IBD cases have a greater prevalence compared to the normal population. The trichrome staining method is more effective for the detection of E. histolytica/E. dispar than the wet mount+Lugol′s iodine staining, modified formol ethyl acetate methods.

关键词：阿米巴病肠炎土耳其流行病学

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