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The Effect of Dexamethasone versus Methylprednisolone in the Treatment of COVID-19 Patients in Jordan

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Advances in Infectious Diseases 2023年第3期13卷 508-520页

作者： Jamal Wadi Al Ramahi Nour Hasan Amal Matar Ma’en Maher Al-Ali Lara Abdulhadi Dania Abu Kaf Waseem Saadeh Nour Hamdan Hassan Abu Khalaf Mohamed Gharaibeh hanadi hamadallah Ala’a Bader Mohammad Atout Sae’ed Moh. Mar’I Tamer Alhamed Department of Medicine School of Medicine The University of Jordan Amman Jordan Clinical Pharmacy Al Khalidi Hospital Amman Jordan Department of General Medicine Al Khalidi Hospital Amman Jordan Department of Clinical Medical Sciences Faculty of Medicine Yarmouk University Irbid Jordan Department of Medicine The Specialty Hospital Amman Jordan Department of Anesthesia The Specialty Hospital Amman Jordan Department of Pharmacy Jordan Hospital Amman Jordan Department of Pharmacy The Specialty Hospital Amman Jordan

Background: Previous studies focused on the treatment effect of steroids versus no steroids in treating severe COVID-19 patients, a few studies evaluated outcomes for treating those patients with either dexamethasone or methylprednisolone. Currently, we evaluate the difference in mortality associated with treating COVID-19 patients with dexamethasone versus methylprednisolone. Methods: With a retrospective multicenter study, records were reviewed for the admitted patients with severe COVID-19 during the peak of the severe COVID-19 pandemic. All admitted patients on dexamethasone or methylprednisolone were included. Patients were analyzed as all populations and propensity scores matched patients. Propensity scores were calculated for several confounders by the generalized linear model, and a “greedy” near-neighbor matching algorithm was used. Continuous variables with nonnormal distribution were analyzed by Wilcoxon signed rank test. Chi-squared and Fischer exact test analyzed categorical variables. P-values were adjusted by the Bonferroni method for both data cohorts. Body mass index was in categories. Radiological findings were divided into five categories. The outcomes: mortality, the need for home oxygen therapy, recovery, and residual symptoms on discharge were analyzed by an independent two-sample test for equality of proportions (with Yates correction), and logistic regression analysis. Results: Among the 1128 reviewed records, patients on dexamethasone or methylprednisolone were 1071, and the propensity score-matched patients were 784: dexamethasone 393 and methylprednisolone 391. There was no significant difference in the characteristics of patients between the two steroids (p-value and adjusted p-value > 0.05) for most variables. PSM adjusted a few discrepant variables before analysis. The outcome of the unmatched patients demonstrated dexamethasone benefit in the need for home oxygen therapy ( 0.05). However, matched patients demonstrated significantly low

关键词： Dexamethasone Methylprednisolone COVID-19 Mortality Home Oxygen COVID-19 Recovery

Radiographic Equipment and Accessories as a Potential Source of Nosocomial Infection

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Open Journal of Radiology 2024年第3期14卷 147-155页

作者： Lina Fahmi Hammad Essam Hussain Mattar hanadi Talal Ahmedah Mohamed Zain Shamweel Ahmad Hiba Shamweel Radiological Sciences Department College of Applied Medical Sciences King Saud University Riyadh KSA Department of Medical Laboratory Technology Faculty of Applied Medical Sciences King Abdulaziz University Rabegh KSA Botany and Microbiology Department College of Science King Saud University Riyadh KSA Department of Medical Laboratory Sciences College of Medical Sciences Prince Sattam Bin Abdulaziz University Al Kharj KSA Al-Haram Diagnostic Research and Training Center Srinagar Kashmir

Background: Nosocomial infections have become a major challenge in healthcare facilities as they affect the quality of medical care. Radiological imaging plays a crucial role in medical diagnosis. However, the equipment and accessories used increase the risk of transmission of nosocomial bacteria. Objective: This study aims to reveal the extent and nature of microbiological contamination in four hospital diagnostic imaging departments to determine their potential role in the spread of nosocomial bacteria and to evaluate the effectiveness of routine daily disinfection practices in controlling microorganisms in diagnostic imaging departments. Methods & Results: In each department, swabs were taken from the surfaces of selected parts of the equipment and accessories three times a day (early morning, noon, and evening) for five consecutive days. Bacteria were isolated from 65 swabs (36.1% of all samples). The bacteria were isolated 3 times (4.6%) in the morning, 16 times (24.6%) at midday, and 46 times (70.7%) in the evening. The bacteria isolated were Escherichia coli (isolated 34 times;52.3%), Staphylococcus aureus (20 times;30.8%), Staphylococcus epidermidis (6 times;9.3%), and Klebsiella species (5 times;7.7%). Discussion & Conclusion: Findings demonstrated that radiology equipment and accessories are not free of bacteria and further improvements in the sterilization and disinfection of radiology equipment and accessories are needed to protect staff and patients from nosocomial infections.

关键词： Diagnostic Imaging Department Nosocomial Infection Radiographic Accessories Radiographic Equipment

Maxillary denture flange and occlusal discrepancies of Vertex ThermoSens in comparison with conventional heat-cured denture base materials

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The Journal of Biomedical Research 2019年第2期33卷 139-144页

作者： hanadi A.Lamfon Ibrahim M.Hamouda Maxillofacial and Oral Rehabilitation Department Umm Al-Qura University Conservative Dentistry Faculty of Dentistry Umm Al-Qura University Dental Biomaterials Faculty of Dentistry Mansoura University

This study was conducted to investigate the maxillary denture bases and occlusal discrepancies using the Vertex Thermosens in comparison with the conventional polymethyl-methacrylate materials. Twenty maxillary denture bases were prepared from the Vertex ThermoSens and a conventional heat-cured denture base materials. Acrylic maxillary second molars were arranged in their respective positions on the ridge. After curing of both types of denture bases, they were deflasked with their respective master casts. Reference points were prepared for measurements of the antero-posterior and cross-arch dimensions at the denture borders using caliper device. Furthermore, the teeth discrepancies were measured between reference points in the ligual aspect of the second maxillary molars. The recorded data was analyzed using SPSS statistical software version 20. The results showed initial shrinkage of both denture bases in the antero-posterior and cross-arch dimensions immediately after decasting. This contraction was compensated gradually during storage in water up to 2 weeks. Regarding the variable time, there was a significant difference between the tested materials. Moreover, the results revealed occlusal discrepancies and shifting of teeth inward immediately after decasting, followed by outward movement after storage in water for 2 weeks. Regarding the variables time and materials, there were significant differences. Both materials exhibited inward shrinkage in the antero-posterior and cross-arch dimensions immediately after decasting. Both denture bases showed inward shifting of teeth immediately after decasting, followed by outward movement after storage in water up to 2 weeks.

关键词： denture distortion flange discrepancy acrylic resin occlusal discrepancies denture base

Arabic Word Handwriting Recognition

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Arabic Word Handwriting Recognition

作者： ALATTAS,hanadi HUSSAIN H 华中师范大学

学位级别：硕士

由于手写阿拉伯文字变种多差异较大,在现有的学习系统上对其进行识别具有极大的挑战性。目前依赖手工方法的识别算法仍然面临着识别率较低以及非常耗时的情况。近年来,深度学习技术在包括手写字体识别在内的许多模式识别应用中都表现出... 详细信息

由于手写阿拉伯文字变种多差异较大,在现有的学习系统上对其进行识别具有极大的挑战性。目前依赖手工方法的识别算法仍然面临着识别率较低以及非常耗时的情况。近年来,深度学习技术在包括手写字体识别在内的许多模式识别应用中都表现出了很强的特征提取能力。然而,对阿拉伯文字手写字体识别的深入研究还很薄弱,我们在本论文中着重评估了卷积神经网络在阿拉伯手写字体识别中的作用。为了进行这项研究,本文使用了功能强大且使用广泛的VGG网络并从头开始训练具有不同体系结构的VGG网络。为了减少过拟合情况的发生,我们在每个最大值池化层之后都应用了 Dropout。该实验是IFN/NIET数据库上进行的,并取得了最高的精度。VGG19在测试集上的总体准确度达到了 95.46%。结果表明,VGG网络用于阿拉伯文字手写字体识别时,其性能与网络的深度呈正相关。最近基于深度神经网络(DNNs)的手写拉丁文字和中文文字识别方法已经取得了一些较好的成果。然而,阿拉伯文字手写字体识别的准确率却很低,这是因为阿拉伯文字手写体的草书性质和个人书写风格的变化仍然是该领域面临的一个巨大挑战。同样在本研究中我们提出了基于IFN/ENIT数据库训练的集成神经网络以便用于离线阿拉伯文字笔迹识别(OAHR)。我们将原始的IFN/ENIT数据进行归一化,使得高度始终等于100像素,而宽度始终等于100,200,300像素。我们针对每种归一化数据训练了一个模型(DNN),并且最终得到了一个总体模型。每个模型配置九层,对输入和输出层进行计数。集成模型提高了多样性,这是构建集成模型所需的主要性质之一。最后,通过使用基准数据库进行几组实验,我们将实验结果与其他方法进行了比较,结果表明我们的方法有了一定程度的改进。

关键词：阿拉伯文字手写字体识别深度学习 VGG Dropout集成深度神经网络

Modeling the Infection Disease (Covid-19) and the Effect of Vaccination

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Applied Mathematics 2023年第7期14卷 437-449页

作者： hanadi Alzubadi Department of Mathematic Umm alQura University Makkah KSA

In this paper we provide different types of approach in mathematical biology about infection disease and understanding the dynamic of epidemic mathematical models specially in COVID-19 disease which first outbroke in China and fast spread around the world. We work in the connection between the mathematical models and the solution analytically and numerically. At first, we emphasize the Susceptible-Infectious-Recovered (SIR) models’ extension for policy significance. Then, we found the improved SIER model done by research. In third section, we examine the improved model when an appropriate vaccine has been found, we introduce the model of SIR with vaccine term which ends up with discussion and conclusion about the effect of vaccinate. The comprehension of COVID-19 transmission methods, structures, and characteristics is greatly aided by these mathematical models analytically and numerically.

关键词： SIR Model SEIR Model COVID-19 Travelling Wave Vaccine Effect Numerical Solution

Intelligent Energy Consumption For Smart Homes Using Fused Machine-Learning Technique

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Computers, Materials & Continua 2023年第1期74卷 2261-2278页

作者： hanadi AlZaabi Khaled Shaalan Taher M.Ghazal Muhammad A.Khan Sagheer Abbas Beenu Mago Mohsen A.A.Tomh Munir Ahmad Faculty of Engineering and IT The British University in DubaiUnited Arab Emirates Center for Cyber Security Faculty of Information Science and TechnologyUniversity Kebangsaan Malaysia(UKM)Bangi43600SelangorMalaysia School of Information Technology Skyline University CollegeUniversity City SharjahSharjah1797United Arab Emirates Riphah School of Computing&Innovation Faculty of ComputingRiphah International University Lahore CampusLahore54000Pakistan Pattern Recognition and Machine Learning Lab. Department of SoftwareGachon UniversitySeongnamGyeonggido13120Korea Faculty of Computer Science NCBA&ELahore54660Pakistan

Energy is essential to practically all exercises and is imperative for the development of personal ***,valuable energy has been in great demand for many years,especially for using smart homes and structures,as individuals quickly improve their way of life depending on current ***,there is a shortage of energy,as the energy required is higher than that *** new plans are being designed to meet the consumer’s energy *** many regions,energy utilization in the housing area is 30%–40%.The growth of smart homes has raised the requirement for intelligence in applications such as asset management,energy-efficient automation,security,and healthcare monitoring to learn about residents’actions and forecast their future *** overcome the challenges of energy consumption optimization,in this study,we apply an energy management *** fusion has recently attracted much energy efficiency in buildings,where numerous types of information are *** proposed research developed a data fusion model to predict energy consumption for accuracy and miss *** results of the proposed approach are compared with those of the previously published techniques and found that the prediction accuracy of the proposed method is 92%,which is higher than the previously published approaches.

关键词： Energy consumption intelligent machine learning technique smart homes prediction

Effect of Pulsed Laser on the Structure and Morphology of Alumina-Zirconia Coatings

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Journal of Surface Engineered Materials and Advanced Technology 2013年第3期3卷 249-256页

作者： Hala Omar Ahmed Ibrahim hanadi Salem Sherif Sedky Department of Mechanical and Manufacturing Engineering Farmingdale State College Farmingdale USA The American University in Cairo Yousef Jameel Science & Technology Center Cairo Egypt Zewail City of Science & Technology Cairo Egypt.

The effect of excimer laser annealing on the structure and morphology of ceramic coatings were investigated. Alumina-40% zirconia (AZ-40) coatings were sprayed with a water-stabilized plasma spray gun. The coated surface was treated by excimer laser having a wavelength of 248 nm and pulse duration of 24 ns. The surface structure of the treated coating was examined by field emission scanning electron microscope (FESEM) and X-ray diffraction (XRD). A detailed parametric study was performed to investigate the effects of different parameters such as laser energy density (fluence), pulse repetition rate (PRR), and the number of shots on the mechanical properties, surface morphology, and microstructure of the coatings. The results of this study indicated that laser energy and pulse repetition rate have significant effects on surface morphology, porosity, and microstructure of the coating.

关键词： Laser Annealing Alumina-Zirconia Coatings Surface Morphology Plasma Sprayed Coatings

Feasibility of Performing Sentinel Lymph Node Biopsy (SLNB) after Mastectomy: A Case Report

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Journal of Cancer Therapy 2010年第2期1卷 91-93页

作者： hanadi Bu-Ali Eleftherios P. Mamouna Aultman Cancer Center Canton OH and Akron General Medical Center Akron USA Aultman Cancer Center Canton OH and Northeastern Ohio Universities College of Medicine Rootstown USA

Introduction: Previous mastectomy remains a contraindication to SLNB as normal drainage patterns of the breast can be disturbed. Patients diagnosed with DCIS on core biopsy and later found to have microinvasive or invasive carci-noma at the time of mastectomy are deprived of the opportunity for SLNB and need to undergo axillary dissection. We explored the option and feasibility of performing SLNB in a 39-year-old female who underwent a simple mastectomy without axillary sampling for extensive DCIS and later found to have microinvasive ductal carcinoma on permanent pathology. Results: Lymphatic mapping using subdermal injection of 99mTc-labeled sulfur colloid and blue dye led to the identification of five SLNs. Histopathologic examination showed no metastasis. Conclusion: SNLB is feasible in this setting. However, before its use is routinely adopted, its feasibility and accuracy has to be demonstrated in larger num-bers of patients in whom a negative SLNB is followed by a completion axillary dissection.

关键词： Sentinel Lymph Node Biopsy Lymphatic Mapping Mastectomy Lymphoscintigraphy Axillary Lymph Node Dissection

Predicted Functional Shifts Due to Type of Soil Microbiome and Watering of Two Wild Plants in Western Region of Saudi Arabia

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Phyton-International Journal of Experimental Botany 2022年第10期91卷 2249-2268页

作者： Lina Baz Aala A.Abulfaraj Manal A.Tashkandi hanadi M.Baeissa Mohammed Y.Refai Aminah A.Barqawi Ashwag Shami Haneen W.Abuauf Ruba A.Ashy Rewaa S.Jalal Department of Biochemistry Faculty of ScienceKing AbdulAziz UniversityJeddah21589Saudi Arabia Biological Sciences Department College of Science&ArtsKing Abdulaziz UniversityRabigh21911Saudi Arabia Department of Biochemistry College of ScienceUniversity of JeddahJeddahSaudi Arabia Department of Chemistry Al-Leith University College Umm Al Qura UniversityMakkahSaudi Arabia Department of Biology College of SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Biology Faculty of Applied ScienceUmm Al-Qura UniversityMakkahSaudi Arabia Department of Biology College of ScienceUniversity of JeddahJeddahSaudi Arabia

The present study aimed to predict differential enrichment of pathways and compounds in the rhizosphere microbiomes of the two wild plants(Abutilon fruticosum and Nitrosalsola vermiculata)and to predict functional shifts in microbiomes due to *** sequencing of 16S rRNA region V3–V4 was done and gene-based microbial compositions were enrolled in PICRUSt to predict enriched pathways and *** results indicated that“ABC transporters”and“Quorum sensing”pathways are among the highest enriched pathways in rhizosphere microbiomes of the two wild plants compared with those of the bulk soil *** highest enriched compounds in soil microbiomes of the two wild plants included five proteins and three enzymes participating in one or more KEGG *** of these eight compounds showed higher predicted enrichment in rhizosphere soil microbiomes,while only one,namely phosphate transport system substrate-binding protein,showed higher enrichment in the surrounding bulk soil *** terms of differentially enriched compounds due to watering,only the dual-specific aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln)amidotransferase subunit A showed higher enrichment in rhizosphere soil of the two wild plants after 24 h of *** of the highly enriched compounds namely branched-chain amino acid transport system ATP-binding protein and branched-chain amino acid transport system substrate-binding protein,are encoded by genes stimulated by the plant’s GABA that participates in conferring biotic and abiotic stresses in plants and improves the plant’s growth *** 3-Oxoacyl-[ACP]reductase,a member of the short-chain alcohol dehydrogenase/reductase(SDR)superfamily,participates in fatty acids elongation cycles and contributes to plant-microbe symbiotic relationships,while enoyl-CoA hydratase has a reverse action as it participates in“Fatty acid degradation”*** methyl-accepting chemotaxis protein is an environmental signal that sense“Bacteri

关键词： Amplicon sequencing PICRUSt KEGG GABA symbionts wild plants