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Value of duplex doppler ultrasonography in non-invasive assessment of children with chronic liver disease

World Journal of Gastroenterology 2010年第48期16卷 6139-6144页

作者： mortada HF el-Shabrawi maissa el-Raziky maha Sheiba hanaa m el-karaksy mona el-Raziky Fetouh Hassanin Abeer Ramadan Department of Pediatrics Cairo University Department of Tropical medicine Cairo University Department of Clinical Pharmacy Misr International University

AIm:To investigate the value of duplex Doppler ultrasonography (US) in the assessment of the hemodynamics of the portal and hepatic veins in a cohort of children with chronic liver disease (CLD) and to detect any relationship between the US changes,etiology and severity (or stage) of CLD. mETHODS:We prospectively enrolled 25 children with biopsy-proven CLD. Thirteen had cirrhosis (aged 8.9 ± 2.0 years) and 12 had chronic hepatitis (aged 9.3 ± 2.3 years). Gray scale and color-coded duplex Doppler US were performed for all,as well as 30 healthy age and sex-matched controls. Findings were correlated with clinical,laboratory and histopathological characteristics. RESULTS:Prominent caudate lobe was detected in 100% of cirrhotics,but none of the chronic hepatitis or controls. Thickened lesser omentum and loss of the triphasic waveform of the hepatic vein were present in 69.2% and 53.8% of cirrhotics vs 33.3% and 8.3% of chronic hepatitis respectively. Portal vein flow velocity was significantly lower (P mpared to controls. Child-Pugh's staging showed a positive correlation with both abnormal hepatic vein waveform and direction of portal blood flow; and a negative correlation with both hepatic and portal vein flow velocities. No correlation with the etiology of CLD could be detected. CONCLUSION:Duplex Doppler added to grayscale US can detect significant morphologic and portal hemodynamic changes that correlate with the severity (stage) of CLD,but not with etiology.

关键词： Chronic hepatitis Chronic liver disease Cirrhosis Doppler Grayscale Pediatrics Ultrasound

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Applicability and efficacy of a model for prevention of perinatal transmission of hepatitis B virus infection:Single center study in Egypt

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World Journal of Gastroenterology 2014年第45期20卷 17075-17083页

作者： hanaa m el-karaksy Lamiaa m mohsen Doa'a A Saleh mona S Hamdy Noha A Yassin mohamed Farouk mohamed E Salit mortada H el-Shabrawi Department of Pediatrics Kasr Al-Ainy School of Medicine Cairo University Department of Community medicine Kasr AlAiny School of Medicine Cairo University Department of Clinical and Chemical Pathology Kasr Al-Ainy School of Medicine Cairo University Department of Obstetrics and Gynecology Kasr Al-Ainy School of Medicine Cairo University

AIm: To identify possible maternal risk factors for hepatitis B virus (HBV) acquisition and assess the efficacy of immunoprophylaxis given to infants born to hepatitis B virus surface antigen (HBsAg) positive mothers.

关键词： Egypt Hepatitis B virus Hepatitis B virus surface antigen positive mothers Immunoprophylaxis Perinatal transmission

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Safety and efficacy of Hansenula-derived PEGylated-interferon alpha-2a and ribavirin combination in chronic hepatitis C Egyptian children

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World Journal of Gastroenterology 2014年第16期20卷 4681-4691页

作者： Suzan el Naghi Tawhida Y Abdel-Ghaffar hanaa el-karaksy elham F Abdel-Aty mona S el-Raziky Aleef A Allam Heba Helmy hanaa A el-Araby Behairy E Behairy mohamed A el-Guindi Hatem el-Sebaie Aisha Y Abdel-Ghaffar Nermin A Ehsan Ahmed m el-Hennawy mostafa m Sira Pediatric Department National Hepatology and Tropical Medicine Research Institute11441 CairoEgypt Yassin Abdel Ghaffar Charity Center for Liver Disease and Research 2851 CairoEgypt Pediatric Department Ain Shams University11566 CairoEgypt Department of Pediatrics Cairo University Pediatric Hospital11562 CairoEgypt Pediatric Hepatology Department National Liver InstituteMenofiya UniversityShebin El-koom32511 MenofiyaEgypt Biochemistry Department National Liver Institute32511 MenofiyaEgypt Clinical Pathology Department Ain Shams University11566 CairoEgypt Pathology Department National Liver InstituteMenofiya UniversityShebin El-koom32511 MenofiyaEgypt Pathology Department Cairo UniversityFaculty of MedicineKasr El-Aini11562 CairoEgypt

AIm: To investigate the safety and efficacy of a Hansenula-derived PEGylated (polyethylene glycol) interferon (IFN)-alpha-2a (Reiferon Retard) plus ribavirin customized regimen in treatment-naïve and previously treate... 详细信息

关键词： Children Chronic hepatitis C Hansenula polymorpha PEGylated interferon Response rate Ribavirin Treatment

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An Efficient Encryption and Compression of Sensed IoT medical Images Using Auto-Encoder

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Computer modeling in Engineering & Sciences 2023年第2期134卷 909-926页

作者： Passent el-kafrawy maie Aboghazalah Abdelmoty m.Ahmed hanaa Torkey Ayman el-Sayed School of Information Technology and Computer Science Nile UniversityGiza12677Egypt math and Computer Science Department Faculty of ScienceMenoufia UniversityMenoufia32511Egypt Department of Computer Engineering College of Computer ScienceKing Khalid UniversityAbha61421Saudi Arabia Computer Science and Engineering Department Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt

Healthcare systems nowadays depend on IoT sensors for sending data over the internet as a common *** ofmedical images is very important to secure patient *** these images consumes a lot of time onedge computing;therefore,theuse of anauto-encoder for compressionbefore encodingwill solve such a *** this paper,we use an auto-encoder to compress amedical image before encryption,and an encryption output(vector)is sent out over the *** the other hand,a decoder was used to reproduce the original image back after the vector was received and *** convolutional neural networks were conducted to evaluate our proposed approach:The first one is the auto-encoder,which is utilized to compress and encrypt the images,and the other assesses the classification accuracy of the image after decryption and *** hyperparameters of the encoder were tested,followed by the classification of the image to verify that no critical information was lost,to test the encryption and encoding *** this approach,sixteen hyperparameter permutations are utilized,but this research discusses three main cases in *** first case shows that the combination of mean Square Logarithmic Error(mSLE),ADAgrad,two layers for the auto-encoder,and RelU had the best auto-encoder results with a mean Absolute Error(mAE)=0.221 after 50 epochs and 75%classification with the best result for the classification *** second case shows the reflection of auto-encoder results on the classification results which is a combination ofmean Square Error(mSE),RmSprop,three layers for the auto-encoder,and RelU,which had the best classification accuracy of 65%,the auto-encoder gives mAE=0.31 after 50 *** third case is the worst,which is the combination of the hinge,RmSprop,three layers for the auto-encoder,and RelU,providing accuracy of 20%and mAE=0.485.

关键词： Auto-encoder cloud image encryption IoT healthcare

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magnetic,dielectric and electrical modulus of Ce^(3+) doped cobalt-magnesium ferrite nanoparticles

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Journal of Rare Earths 2024年第2期42卷 373-382,I0005页

作者： N.m.Basfer hanaa Almaghamsi Department of Physics Umm AL-Qura UniversityMakkahSaudi Arabia Physics Department College of Science and ArtKing Abdulaziz UniversityPOB344Rabigh291Saudi Arabi

In this work,the magnetic,dielectric properties and electric modulus of Ce^(3+) substituted cobaltmagnesium(Co_(0.7)mg_(0.3)Ce_(x)Fe_(2-x)O_4)(labeled as CmCF) ferrite nanoparticles were investigated in *** magnetization decreases from 50.05 to 34.87 emu/g for further substituting Ce^(3+) ***,coercivity increases from 738.22 Gs for the CmCFO sample to 912.10 Gs for the CmCF2 sample,then decreases monotonically to 762.1 Gs for the CmCF5 *** cerium content and particle size play important roles in controlling the magnetization and coercivity of the CmCF *** CmCF nanoferrites are suitable for microwave applications since their high-frequency response ranges from 7.72 to 11.07 *** CmCF nanoferrites' dielectric parameter dispersion exhibits normal *** pristine Co-mg nanoferrite only has ε' value of 28.25,but the nanoferrite mCmF2 has ε' value of365.03,with an enhancing ratio of 1192%.The conduction mechanism of the mCmF nanoferrites was determined by fitting the σ_(ac) results via the Jonscher power *** 653 K,large polaron tunnelling is thought to be responsible for this conduction process,which is followed by electron barrier hopping at higher ***-Cole diagrams at different temperatures,assuring the contributions of the grains and their boundaries at lower temperatures(653 K) and only the grains at higher *** on our results,the CmCF nanoferrites hold magnetic and semiconducting nature,which can be used in magnetic devices and dielectrics in lower-frequencies or conductors in higher-frequencies.

关键词： Nanoferrites Rare earth ions magnetic properties Dielectric parameters Impedance spectroscopy

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Experimental evaluation of Odonata nymph in the biocontrol of schistosomiasis intermediate hosts

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Asian Pacific Journal of Tropical Biomedicine 2016年第12期6卷 995-1000页

作者： Aly Younes hanaa el-Sherief Fathia Gawish marwa mahmoud Department of Entomology Faculty of ScienceCairo University Department of medical malacology Theodor Bilharz Research Institute

Objective:To evaluate the predatory potential of the Odonata nymph on freshwater snails that serve as intermediate hosts for Schistosoma species(Bulinus truncatus and Biomphalaria alexandrina).methods:Observations on the searching,attacking and devouring of the two snail types with series of laboratory-based predation experiments,whose aims were to determine daily predation rate,differential predation,prey preference considering small-,mediumand large-sized snails were ***:Laboratory evaluation revealed that,the Odonata nymph could kill and consume the two intermediate *** number of snails consumed differed according to the snail type,size and *** times taken for searching and handling times were dependent on the snail size,type and satiation of the *** predation rate varied also with respect to snail type,size and *** study also evaluated that Odonata nymphs consumed more Bulinus truncatus than Biomphalaria alexandrina per unit time,and that there may be a preference for smaller than larger ***:According to our observation,the predator,Hemianax ephippiger nymph may be a suitable biocontrol agent in connection with Schistosoma intermediate hosts.

关键词： Schistosoma Intermediate hosts Snails Biological control

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Hazardous effects of fried potato chips on the development of retina in albino rats

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Asian Pacific Journal of Tropical Biomedicine 2011年第4期1卷 253-260页

作者： Hassan I el-Sayyad Saber A Sakr Gamal m Badawy hanaa S Afify Department of Zoology Faculty of ScienceMansoura UniversityMansouraEgypt Department of Zoology Faculty of ScienceMenoufiya UniversityShebin El-komEgypt

Objective:To evaluate the hazardous effects of fried potato chips upon the retina of two developmental stages of the albino rats aged 7 and 14 days from ***:Pregnant rats were arranged into two groups:control pregnant rats and consequently their delivered newborns until reaching 7 and 14 days old from parturition and fried potato chips group in which pregnant rats at the 6th day of gestation maintained on diet formed of fried potato chips supplied from the market mixed with standard diet at a concentration of 50%per each till 7 and 14 *** fold integrated approaches were adopted,namely,histological,ultrastructural and proteomic ***:Histological examination of the retina of the experimental offsprings revealed many histopathological changes,including massive degeneration,vacuolization and cell loss in the ganglion cell layer,as well as general reduction in retinal *** the ultrastructural level,the retina of experimental offsprings exhibited number of deformities,including ill differentiated and degenerated nuclear layer,malformed and vacuolated pigment epithelium with vesiculated and fragmented rough endoplasmic reticulum,degenerated outer segment of photoreceptors,as well as swollen choriocapillaris and loss of neuronal *** analysis of retina of the two experimental developmental stages showed variations in the expressed proteins as a result of intoxication which illustrated the adverse toxic effects of fried potato chips upon the ***:It can be concluded that the effect of fried potato chips on the development of retina in rats may be due to the presence of acrylamide or its metabolite.

关键词： Fried potato chips Retina Development Histology Ultrastructure Albino rats Hazardous effect Proteomic analysis Acrylamide metabolite

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PVC nanocomposites for cable insulation with enhanced dielectric properties,partial discharge resistance and mechanical performance

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High Voltage 2020年第4期5卷 463-471页

作者： Nagat m.K.Abdel-Gawad Adel Z.el Dein Diaa-eldin A.mansour hanaa m.Ahmed mohamed m.F.Darwish matti Lehtonen Department of electrical Power and machines Engineering Faculty of Engineering at ShoubraBenha UniversityCairoEgypt Department of High Voltage Networks Faculty of Energy EngineeringAswan UniversityAswanEgypt High Voltage and Superconductivity Laboratory Department of Electrical Power and Machines EngineeringFaculty of EngineeringTanta UniversityTantaEgypt Department of mathematics and Engineering Physics Faculty of Engineering at ShoubraBenha UniversityCairoEgypt Department of electrical Engineering and Automation School of Electrical EngineeringAalto UniversityEspooFinland

The current study aims to develop polyvinyl chloride(PVC)nanocomposites with enhanced electrical and mechanical properties by incorporating titanium oxide(TiO_(2))nanoparticles within PVC *** loading of nanoparticles and different nanoparticle surface states were *** surface states are unfunctionalised,functionalised using vinyl silane and functionalised using amino *** choice of a most suitable surface state was a critical factor that guarantees a good dispersion of nanoparticles and consequently enhances the compatibility between TiO_(2)and PVC *** process followed in the PVC/TiO_(2)nanocomposites preparation,loaded with different wt.%of TiO_(2)nanoparticles,was the solvent *** dielectric properties measured here were the relative permittivity(ɛr),dielectric loss(tanδ),breakdown strength(AC and DC under uniform field)and the internal partial discharges(PDs)within insulation *** measurements have been performed under room temperature and at frequency ranged from 20 to 1.0 ***,the mechanical properties of the samples like elongation,elasticity modulus and tensile strength were also *** silane showed better improvements in both electrical and mechanical performances compared to the amino silane,especially in cases of high weight fractions of TiO_(2).This is because of the improvement in the PVC-TiO_(2)interfacial region arise from the similarity of polarity and surface tension values of vinyl silane with that of PVC matrix and TiO_(2)nanoparticles.

关键词： dielectric insulation resistance

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Study of Luminous Emission from a Coaxial Plasma Discharge Device in the Presence of External Transverse magnetic Field

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Energy and Power Engineering 2011年第4期3卷 444-449页

作者： Tarek m. Allam hanaa A. el-Sayed hanaa m. Soliman 不详

The experimental investigations in this paper are focused on the study of luminous radiation emission from coaxial plasma discharge device and the effect of applied transverse magnetic field Btr on it. The experiment was done in (1.5 KJ - 10 KV) coaxial plasma discharge device. The discharge is operated in Nitrogen gas at pressures from 1 to 2.2 torr. Helmholtz magnetic coils are placed outside the coaxial electrodes with its axis at a distance = 3 cm from the coaxial electrodes muzzle, then Btr with a maximum induction ≈ 0.85 T is applied perpendicularly to the expanded plasma from the coaxial electrodes muzzle. The diagnostics used in the measurements include a Rogowsky coil and a photomultiplier tube equipped with light collimator. The experimental results showed that the maximum intensity of luminous radiation is detected at axial distance (side view) z = 8 cm and gas pressure, P = 2.2 torr. It also showed that the maximum value of axial luminous plasma zone velocity = 2.383 × 106 cm/s at z = 11 cm and P = 1.4 torr. In mode of presence of external Btr, the investigations have shown that, at P = 1.4 torr the maximum intensity of luminous radiation (detected at end-view position) is reduced by 17%, the full width at half maximum, FWHm of luminous radiation signal is increased by 40 times, while the luminous radiation signal is delayed by ta = 438 μs. In two modes of operation ta and FWHm have approximately a minimum values at P = 1.4 torr.

关键词： Coaxial Discharge Luminous Radiation Transverse magnetic Field Energy Losses

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Flavonoid chemical composition and antidiabetic potential of Brachychiton acerifolius leaves extract

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Asian Pacific Journal of Tropical Biomedicine 2017年第5期7卷 389-396页

作者： Aisha Hussein Abou Zeid mohamed Ali Farag manal Abdel Aziz Hamed Zeinab Abdel Aziz Kandil Radwa Hassan el-Akad hanaa mohamed el-Rafie Pharmacognosy Department National Research Centre Pharmacognosy Department College of PharmacyCairo University Therapeutic Chemistry Department National Research Centre

Objective:To evaluate Brachychiton acerifolius leaf extracts as antidiabetic potential agent and to identify the main active constituents using bioactivity guided ***:In vitro antioxidant activity was evaluated for *** different extracts using DPPH assay and vitamin C as *** activity was then determined using STZ-induced rats treated daily with ethyl acetate and 70% ethanol leaf extracts for4 weeks at a dose of 200 g/kg body weight against gliclazide reference *** glucose,a-amylase,lipid profile,liver function enzymes and oxidative stress markers were assessed along with histopathological study for liver and pancreatic *** and structural elucidation of active compounds were made using Diaion and Sephadex followed by spectral ***:The results indicated that ethyl acetate and ethanol leaf extracts exhibited the strongest antioxidant activity compared to that of vitamin C(IC500.05,0.03 and 12 mg/m L,respectively).Both extracts showed potent anti-hyperglycemic activity evidenced by a significant decrease in serum glucose levels by 82.5% and 80.9% and a-amylase by45.2% and 53.6%,as compared with gliclazide 68% and 59.4%,*** of ethanol extract resulted in the isolation of 9 flavonoids including apigenin-7-O-arhamnosyl(1/2)-b-D-glucuronide,apigenin-7-O-b-D-glucuronide,apigenin-7-O-b-Dglucoside and ***:This study highlights the potential use of *** leaf extract enriched in flavones for the treatment of diabetes that would warrant further clinical trials investigation.

关键词： STZ-induced diabetes Diaion fractionation Flavonoid glucuronides Brachychiton acerifolius

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