检索结果-南通市图书馆

Structural identification of active moiety in anti-tumor metastatic polysaccharide purified from fermented barley by sequential enzymatic hydrolysis

在线全文

学校读者我要写书评

暂无评论

Food Bioscience 2022年第6期50卷 139-149页

作者： Seung-U Son han wool Kim Kwang-Soon Shin Department of Food Science and Biotechnology Kyonggi UniversitySuwon16227Republic of Korea Transdisciplinary Major in Learning Health System Department of Integrated Biomedical and Life ScienceKorea UniversitySeoul02841Republic of Korea

The potent anti-cancer metastatic effects induced by the immunostimulatory activities of intravenously administered BF–I,an active polysaccharide purified from fermented barley,were previously *** study aimed to evaluate the anti-cancer metastatic effect of orally administered BF–I and elucidated the microstructure and active moiety of BF–I using sequential enzymatic *** experiments using Colon26-M3.1 carcinoma,prophylactic oral administration of BF–I potently suppressed lung cancer ***,gas chromatography-mass spectrometry analysis of partially methylated alditol acetate showed that BF–I comprised 15 different glycosyl linkages,including 4-linked Xylp(16.1%),terminal Araf(12.4%),4-linked Glcp(32.8%),3-linked Glcp(13.5%),3,6-linked Glcp(1.5%),and 3,6-linked Galp(5.3%).These glycosyl linkage combinations are typical for arabinoxylan,yeast-derivedβ-glucan,barley-derivedβ-glucan,and type II *** clarify the microstructure,BF–I was sequentially degraded via linkage-specific enzymatic hydrolysis using five ***,the sugar composition,glycosyl linkage,and reactivity with theβ-glucosyl Yariv reagent were analyzed,along with sequencing based on tandem mass spectra of partially degraded fragment *** results confirmed that BF–I comprises a mixture of four different types of polysaccharides(arabinoxylan,yeast-derivedβ-glucan,barley-derivedβ-glucan,and type II arabinogalactan)with similar molecular ***,different polysaccharides contribute significantly to cytokine(interleukin-6,-12,and tumor necrosis factor-α)secretion by peritoneal ***,the potent anti-cancer metastatic activity of BF–I is proposed to be related to the immunostimulatory activities of the four different types of polysaccharides.

关键词： Barley Polysaccharide structure Anti-cancer Enzymatic hydrolysis

Effects of intravenous administration of polysaccharide purified from fermented barley on tumor metastasis inhibition via immunostimulating activities

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Bioscience 2022年第5期49卷 130-138页

作者： Seung-U Son han wool Kim Min Seung Park Kwang-Soon Shin Department of Food Science and Biotechnology Kyonggi UniversitySuwon16227Republic of Korea Transdisciplinary Major in Learning Health System Department of Integrated Biomedical and Life ScienceGraduate SchoolKorea UniversitySeoul02841Republic of Korea

The present study was aimed that determine the effects of polysaccharide isolated from fermented barley about tumor metastasis inhibition via immune related factors such as complementary system,macrophages,natural killer(NK)cells,and cytotoxic T lymphocyte(CTL).To characterize the tumor inhibition effects through immunostimulation of polysaccharides purified from fermented barley,the active crude polysaccharide(BF-CP)was isolated from fermented barley and further fractionated into three purified polysaccharides(BF-I,-II,and-III)with different molecular weights through gel permeation ***-I was mainly composed of four monosaccharides,including xylose(32.90%),arabinose(26.71%),and glucose(33.43%).BF-I augmented the secretion of cytokines,such as interleukin(IL)-6,IL-12,and tumor necrosis factor-α,through peritoneal macrophages and potently activated the complement *** the experiment for NK cells and CTL activities,intravenous(i.v.)administration of BF-I significantly augmented the cytotoxicity of NK cells and CTL-mediated cytotoxicity against tumor *** addition,*** of BF-I potently inhibited tumor metastasis in a mouse model of lung cancer and tumor metastasis in mice with suppressed NK cell function through anti-asialo ***,BF-I shows potent tumor inhibition effects,and these effects are related to various immune factors such as macrophages,the complement system,NK cells,and ***,BF-I,the polysaccharide purified from fermented barley possess the new possibility for developing functional foods and medical ingredients.

关键词： Fermented barley Polysaccharide Immune system Anti-cancer

Femtosecond Tm-Ho co-doped fiber laser using a bulk-structured Bi2Se3 topological insulator

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2018年第9期27卷 137-143页

作者： Jinho lee Ju han lee School of Electrical and Computer Engineering University of SeoulSeoul 02504Republic of Kore

We experimentally demonstrate a femtosecond mode-locked thulium-holmium（Tm-Ho） co-doped fiber laser incorporating a saturable absorber（SA） based on a bulk-structured bismuth selenide（Bi2Se3） topological insulator（TI）. The SA was prepared by depositing a mechanically exfoliated Bi2Se3 TI layer onto a side-polished optical fiber platform. Unlike high-quality nano-structured Bi2Se3 TI-based SA, bulk-structured Bi2Se3 with non-negligible oxidation was used as a saturable absorption material for this experimental demonstration due to its easy fabrication process. The saturation power and modulation depth of the prepared SA were measured to be -28.6 W and -13.4%, respectively. By incorporating the prepared SA into a Tm-Ho co-doped fiber ring cavity, stable soliton pulses with a temporal width of - 853 fs could be generated at 1912.12 nm. The 3-dB bandwidth of the mode-locked pulse was measured to be -4.87 nm. This experimental demonstration reaffirms that Bi2Se3 is a superb base material for mid-infrared passive mode-locking even under oxidation.

关键词： topological insulator mode-locked lasers femtosecond pulse fiber lasers

Optimal Control of a Mackerel-Mimicking Robot for Energy Efficient Trajectory Tracking

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2007年第4期4卷 209-215页

作者： Seunghee lee Jounghyun Park Cheolheui han Department of Mechanical Engineering hanyang University Seoul 133-791 Korea Department of Aeronautical and Mechanical Design Engineering Chungju National University Chungju 380-702 Korea

A robotic fish, BASEMACK1, is designed and fabricated by mimicking the shape of a live mackerel. Three DC servo-motors are serially linked together and actuated to mimic the mackerel＇s Carangiform motion. Hydrodynamic characteristics of a fish-mimetic test model are experimentally identified and utilized in order to numerically simulate fish swimming. The discrete set of kinematic and dynamic parameters are obtained by considering required horizontal and lateral forces and minimum energy consumption. Using the optimized parameter set, optimal control of the robot is studied.

关键词： mackerel-mimicking robot optimal control trajectory tracking

Synthesis of crosslinked polystyrene particles by seeded batch polymerization with monomer absorption

在线全文

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2011年第A01期21卷 153-159页

作者： Ki-Chang lee han-Ah WI Department of Polymer Science and Engineering Engineering Research Institute Gyeongsang National University

A highly crosslinked, monodispersed polystyrene（PS） particle was prepared by a seeded batch dispersion polymerization with a monomer absorption method. Prior to polymerization, 1,9 lam monodispersed PS seed particles were treated under an optimum condition of monomer absorption. The effects of divinylbenzebe（DVB） concentration and polymerization temperature were examined for styrene（in PS seed）/styrene（in the second stage） mass ratio of 1：1 in the medium range of EtOH/water mass ratio of 100/0-80/20 and 2.3 μm uniform crosslinked PS particles containing 15%-20% （mass fraction） DVB were prepared at 60-70 ℃. The results show that monomer absorption before the second stage of polymerization is more effective to prepare highly crosslinked monodispersed PS particles.

关键词： crosslinked polystyrene particle seeded batch dispersion polymerization monomer absorption divinylbenzene (DVB)

A Study on the Effects of the Intake Port Configurations on the Swirl Flow Generated in a Small D.I. Diesel Engine

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2014年第3期23卷 297-306页

作者： Yungjin Kim Yongtaek han Kihyung lee Department of Mechanical Engineering Hanyang University

This paper investigates the effect of intake port configuration on the swirl that is generated within a direct injection(D.I.) diesel engine. The in-cylinder flow characteristics are known to have significant effects on fuel-air mixing, combustion, and emissions. To clarify how to intensify the swirl flow, a swirl control valve(SCV) and a bypass were selected as design parameters for enhancing the swirl flow. The optimal intake port shape was also chosen as a parameter needed to efficiently generate a high swirl ratio. The results revealed that a key factor in generating a high swirl ratio was to control the intake airflow direction passing through the intake valve seat. Further, the swirl intensity was influenced by changing the distance between the helical and tangential ports, and the swirl flow was changed by the presence of a bypass near the intake valve seat. Additionally, the effect of intake port geometry on the in-cylinder flow field was investigated by using a laser sheet visualization method. The experimental results showed a correlation of swirl ratio and mass flow rate. In addition, we found that employing the bypass was an effective method to increase swirl ratio without sacrificing mass flow rate.

关键词： helical intake port ISM(impulse swirl meter) swirl ratio intake flow rate PIV(particle image ve-locimetry) HSDI(high speed direct injection)

Infrared Brazing Zirconium using Two Silver Based Foils

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2013年第3期29卷 283-286页

作者： Cheng-han lee Ren-Kae Shiue Department of Materials Science and Engineering National Taiwan University

Ag-based brazing foils, BAg-8 （72Ag-28Cu in wt%） and Ticusil （68.8Ag-26.7Cu-4.5Ti in wt%） were selected to braze Zr. Interfacial AgCu4Zr, CuZr2 reaction layers and Ag-rich matrix dominate BAg-8 brazed joint, and fractograph after shear test shows ductile dimple fracture with plastic sliding marks. Ticusil joint brazed at 910℃ for 300 s is comprised of CugZr11 and AgZr intermetallics, and fractograph after shear test displays brittle cleavage fracture.

关键词： Brazing Zirconium Microstructura! evolution

Macrophage activation syndrome in children with Kawasaki disease: diagnostic and therapeutic approaches

在线全文

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2020年第6期16卷 566-574页

作者： Seung Beom han Soo-Young lee Department of Pediatrics Daejeon St.Mary's Hospital.College of MedicineThe Catholic University of Korea64 Daeheung-ro.Jung-guDaejeon 34943Republic of Korea Department of Pediatrics.Bucheon St.Mary's Hospital College of MedicineThe Catholic University of Korea327 Sosa-roWonmi-gu.Bucheon 14647Republic of Korea

Background Macrophage activation syndrome(MAS)is a rare,life-threatening complication of Kawasaki disease(KD).Early recognition and treatment of MAS are very important,but sometimes it is difficult to distinguish MAS from a severe form of *** sources A PubMed search was performed in Clinical Queries using the key terms“macrophage activation syndrome or secondary hemophagocytic lymphohistiocytosis(HLH)”and“Kawasaki disease”.Results KD patients with MAS show high intravenous immunoglobulin(IVIG)resistance and coronary *** is also as high as MAS in other *** fever greater than 10 days is highly associated with development of MAS in *** is observed in more than two-thirds of KD patients with *** is often the earliest laboratory finding of *** is highly specific and sensitive for detecting MAS in KD;so,ferritin levels should be checked if there are unexplained clinical exacerbations in KD *** the under-recognition of MAS in KD,it is prudent to consider resistant KD as occult/subclinical *** KD patients with MAS have good outcomes on immune ***,if KD patients fulfill the HLH-2004 diagnostic criteria,they may undergo longer and more intensive treatment than *** The possible existence of MAS should be taken into account when a KD patient shows persistent fever,splenomegaly,thrombocytopenia,hyperferritinemia,or IVIG *** under-diagnosis of MAS in patients with KD is an important issue to be ***,however,there is a possibility of over-treatment of MAS in patients with KD.

关键词： Macrophage activation syndrome Kawasaki disease Children

Enhancing the total organic carbon measurement efficiency for water samples containing suspended solids using alkaline and ultrasonic pretreatment methods

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2020年第4期32卷 20-28页

作者： han-Saem lee Jin Hur Hyun-Sang Shin Department of Environment Energy Engineering Seoul National University of Science&TechnologySeoul01811South Korea Department of Environment&Energy Sejong UniversitySeoul05006South Korea

In this study,we investigated the effect of sample pretreatments(ultrasonication and alkaline extraction)on total organic carbon(TOC)measurements for water samples containing suspended solids(SS)of four different origins(algae,soil,sewage sludge,and leaf litter)to more clearly assess the impact of particulate organic carbon(POC)in *** effects each of ultrasonication(power,pulse,etc.)and alkaline extraction condition(concentration,time,etc.)on the TOC recovery and precision were investigated,and the results were compared with those of a new sample pre treatment method combining both *** treatment(0.01 mol/L NaOH)showed higher precision than ultrasonication(100/5 on/off pulse),and notably,the differences among the measured TOC values in samples of different origins were also further reduced in the alkaline *** suggests that the ultrasonic pretreatment results can be mainly attributed to the increase in POC recovery through particle size reduction,whereas the alkaline treatment results are achieved through the enhancement of POC *** is also particularly noteworthy that a higher TOC recovery of 87.6%±7.4%with a higher precision of 8.4%could be obtained using the combined method,compared to each treatment(ultrasonic:TOC recovery 34.7%,relative standard deviation 63.1%;alkaline:49.6%and 23.0%,respectively).Thus,simultaneous pretreatment with ultrasonication and alkaline extraction is expected to increase the oxidation rate of organic matter and the homogeneity of the samples,minimizing the loss of POC measurement values,and thereby improving the reliability of the TOC measurements of water samples containing SS.

关键词： Total organic carbon Suspended solids Pretreatment Ultrasonication Alkaline extraction