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11.2 W/mm power density AlGaN/GaN high electron-mobility transistors on a GaN substrate

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Journal of Semiconductors 2024年第1期45卷 38-41页

作者： Yansheng Hu Yuangang Wang Wei Wang Yuanjie Lv Hongyu Guo Zhirong Zhang Hao Yu Xubo Song Xingye zhou Tingting han shaobo Dun Hongyu Liu Aimin Bu Zhihong Feng National Key Laboratory of Solid-State Microwave Devices and Circuits Hebei Semiconductor Research InstituteShijiazhuang 050051China

In this letter,high power density AlGaN/GaN high electron-mobility transistors(HEMTs)on a freestanding GaN substrate are *** asymmetricΓ-shaped 500-nm gate with a field plate of 650 nm is introduced to improve microwave power *** breakdown voltage(BV)is increased to more than 200 V for the fabricated device with gate-to-source and gate-to-drain distances of 1.08 and 2.92μm.A record continuous-wave power density of 11.2 W/mm@10 GHz is realized with a drain bias of 70 *** maximum oscillation frequency(f_(max))and unity current gain cut-off frequency(f_(t))of the AlGaN/GaN HEMTs exceed 30 and 20 GHz,*** results demonstrate the potential of AlGaN/GaN HEMTs on freestanding GaN substrates for microwave power applications.

关键词： freestanding GaN substrates AlGaN/GaN HEMTs continuous-wave power density breakdown voltage Γ-shaped gate

Nonlinear optical properties of WSe_2 and MoSe_2 films and their applications in passively Q-switched erbium doped fiber lasers

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Photonics Research 2018年第10期6卷 I0017-I0023页

作者： WENJUN LIU MENGLI LIU HAINIAN han shaobo FANG HAO TENG MING LEI ZHIYI WEI State Key Laboratory of Information Photonics and Optical Communications School of Science Beijing University of Posts and Telecommunications Beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences

Transition metal dichalcogenides(TMDs) are successfully applied in fiber lasers for their photoelectric ***, in previous work, how to improve the modulation depth of TMD-based saturable absorbers(SAs) has been a challenging issue. In this paper, WSe_2 and MoSe_2 SAs are fabricated with the chemical vapor deposition method. Compared with previous experiments, the modulation depths of WSe_2 and MoSe_2 SAs with sandwiched structures are effectively increased to 31.25% and 25.69%, respectively. The all-fiber passively Q-switched erbium doped fiber lasers based on WSe_2 and MoSe_2 SAs are demonstrated. The signal-to-noise ratios of those lasers are measured to be 72 and 57 dB, respectively. Results indicate that the proposed WSe_2 and MoSe_2 SAs are efficient photonic devices to realize stable fiber lasers.

关键词：光电性能激光器通讯技术发展现状

Quasi-omnibearing retro-reflective metagrating protected by reciprocity

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Photonics Research 2022年第4期10卷 843-854页

作者： Yuxiang Jia Jiafu Wang Yajuan han Ruichao Zhu Zhongtao Zhang Jie Yang Yueyu Meng Yongfeng Li shaobo Qu Department of Basic Sciences Air Force Engineering UniversityXi’an 710051China Shaanxi Key Laboratory of Artificially-Structured Functional Materials and Devices Xi'an 710051China

Reciprocity is ubiquitous in antennas for receiving and radiating electromagnetic(EM) waves, i.e., if an antenna has good receiving performance at a given direction, it also has good radiation performance in that *** by this, we propose a method of designing a quasi-ominibearing retro-reflective metagrating(RRMG)protected by the reciprocity of antennas. Based on the second-order mode around 15.0 GHz of a short-circuited structured patch antenna(SPA), incident transverse magnetic waves can be received, channeled into the coaxial lines, reflected by the shortened end, and finally re-radiated into free space with a reversed wave vector. RRMGs are contrived consisting of this identical SPA, with a grating constant allowing ±2nd-, ±1st-, and zeroth-order diffractions. Oblique incidence, plus the tilted nulls of the re-radiation pattern, can eliminate -1st, zeroth,+1st, and +2nd orders, and only the -2nd order is left to achieve retro-reflections. Prototypes were fabricated and measured. Simulated and measured results show that the RRMGs maintain only -2nd-order diffraction for incident angles 32.2° ≤ θ_(i)< 90.0° in four quadrants, and that RRMGs can achieve quasi-omnibearing retro-reflections for θ_(i)= 50.0°. The use of higher-order diffraction brings more degrees of freedom in manipulating EM waves, and this strategy can be readily extended to millimeter waves, THz wave, or even optical regimes.

关键词： reflective antenna antennas

GLUT3 induced by AMPK/CREB1 axis is key for withstanding energy stress and augments the efficacy of current colorectal cancer therapies

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Signal Transduction and Targeted Therapy 2020年第1期5卷 965-978页

作者： Weixing Dai Ye Xu shaobo Mo Qingguo Li Jun Yu Renjie Wang Yanlei Ma Yan Ni Wenqiang Xiang Lingyu han Long Zhang Sanjun Cai Jun Qin Wen-Lian Chen Wei Jia Guoxiang Cai Department of Colorectal Surgery Fudan University Shanghai Cancer CenterShanghaiChina Department of Oncology Shanghai Medical CollegeFudan UniversityShanghaiChina Department of Surgery Johns Hopkins University School of MedicineBaltimoreMD 21287USA The Children’s Hospital School of MedicineZhejiang UniversityZhejiangChina The Key Laboratory of Stem Cell Biology CAS Center for Excellence in Molecular Cell ScienceInstitute of Health SciencesShanghai Institutes for Biological SciencesChinese Academy of SciencesShanghaiChina Cancer Institute Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai 200032China University of Hawaii Cancer Center HonoluluHI 96813USA School of Chinese Medicine Hong Kong Baptist UniversityKowloon TongHong KongChina

Cancer cells are usually characterized by hyperactive glucose metabolism,which can often lead to glucose scarcity;thus,alternative pathways to rewire cancer metabolism are ***,we demonstrated that GLUT3 was highly expressed in colorectal cancer(CRC)and negatively linked to CRC patient outcomes,whereas GLUT1 was not associated with CRC *** glucoselimiting conditions,GLUT3 expedited CRC cell growth by accelerating glucose input and fuelling nucleotide ***,GLUT3 had a greater impact on cell growth than GLUT1 under glucose-limiting ***,low-glucose stress dramatically upregulated GLUT3 via the AMPK/CREB1 ***,high GLUT3 expression remarkably increased the sensitivity of CRC cells to treatment with vitamin C and vitamin C-containing ***,the results of this study highlight the importance of the AMPK/CREB1/GLUT3 pathway for CRC cells to withstand glucose-limiting stress and underscore the therapeutic potential of vitamin C in CRC with high GLUT3 expression.

关键词： GLUT3 vitamin AMPK

Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment

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Chinese Chemical Letters 2023年第2期34卷 65-88页

作者： Rui Liu Cong Luo Zhiqing Pang Jinming Zhang shaobo Ruan Meiying Wu Lei Wang Tao Sun Nan Li Liang han Jinjin Shi Yuanyu Huang Weisheng Guo Shaojun Peng Wenhu Zhou Huile Gao Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial TechnologyWest China School of PharmacySichuan UniversityChengdu 610041China Department of Pharmaceutics Wuya College of InnovationShenyang Pharmaceutical UniversityShenyang 110016China Department of Pharmaceutics School of PharmacyFudan UniversityKey Laboratory of Smart Drug DeliveryMinistry of EducationShanghai 200433China State Key Laboratory of Southwestern Chinese Medicine Resources Pharmacy SchoolChengdu University of Traditional Chinese MedicineChengdu 611130China Advanced Research Institute of Multidisciplinary Science Beijing Institute of TechnologyBeijing 100081China School of Pharmaceutical Sciences(Shenzhen) Sun Yat-sen UniversityShenzhen 518107China School of Pharmaceutical Sciences Zhengzhou UniversityKey Laboratory of Targeting Therapy and Diagnosis for Critical DiseasesZhengzhou 450001China Tianjin Key Laboratory of Drug Delivery&High-Efficiency School of Pharmaceutical Science and TechnologyTianjin UniversityTianjin 300072China Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences Soochow UniversitySuzhou 215123China Advanced Research Institute of Multidisciplinary Science School of Life ScienceKey Laboratory of Molecular Medicine and BiotherapyKey Laboratory of Medical Molecule Science and Pharmaceutics EngineeringBeijing Institute of TechnologyBeijing 100081China Radiology Center Key Laboratory of Molecular Target&Clinical PharmacologySchool of Pharmaceutical Sciences&The Second Affiliated HospitalGuangzhou Medical UniversityGuangzhou 510260China Zhuhai Institute of Translational Medicine Zhuhai People's Hospital(Zhuhai hospital affiliated with Jinan University)Zhuhai 519000China Xiangya School of Pharmaceutical Sciences Central South UniversityChangsha 410013China

Decades have passed since the first nanoparticles-base medicine was approved for human cancer treatment, and the research and development of nanoparticles for drug delivery are always ***, the significant advances complicate nanoparticles’ branches, including liposomes, solid lipid nanoparticles, inorganic nanoparticles, micelles, nanovaccines and nano-antibodies, etc. These nanoparticles show numerous capabilities in treatment and diagnosis of stubborn diseases like cancer and neurodegenerative diseases, emerging as novel drug carriers or therapeutic agents in future. In this review, the complicated branches of nanoparticles are classified and summarized, with their property and functions concluded. Besides, there are also some delivery strategies that make nanoparticles smarter and more efficient in drug delivery, and frontiers in these strategies are also summarized in this review. Except these excellent works in newly-produced drug delivery nanoparticles, some points of view and future expectations are made in the end.

关键词： Nanoparticles Drug delivery Nanomaterials Delivery strategies Specific delivery Disease diagnosis Disease treatment

Complete-basis-reprogrammable coding metasurface for generating dynamicallycontrolled holograms under arbitrary polarization states

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Opto-Electronic Advances 2024年第9期7卷 65-80页

作者： Zuntian Chu Xinqi Cai Ruichao Zhu Tonghao Liu Huiting Sun Tiefu Li Yuxiang Jia Yajuan han shaobo Qu Jiafu Wang Shaanxi Key Laboratory of Artificially-Structured Functional Materials and Devices Air Force Engineering UniversityXi’an 710051China Suzhou Laboratory Suzhou 215000China Zhijian Laboratory Rocket Force University of EngineeringXi’an 710025China.

Reprogrammable metasurfaces,which establish a fascinating bridge between physical and information domains,can dynamically control electromagnetic(EM)waves in real time and thus have attracted great attentions from researchers around the *** control EM waves with an arbitrary polarization state,it is desirable that a complete set of basis states be controlled independently since incident EM waves with an arbitrary polarization state can be decomposed as a linear sum of these basis *** this work,we present the concept of complete-basis-reprogrammable coding metasurface(CBR-CM)in reflective manners,which can achieve independently dynamic controls over the reflection phases while maintaining the same amplitude for left-handed circularly polarized(LCP)waves and right-handed circularly polarized(RCP)*** LCP and RCP waves together constitute a complete basis set of planar EM waves,dynamicallycontrolled holograms can be generated under arbitrarily polarized wave *** dynamically reconfigurable metaparticle is implemented to demonstrate the CBR-CM’s robust capability of controlling the longitudinal and transverse positions of holograms under LCP and RCP waves ***’s expected that the proposed CBR-CM opens up ways of realizing more sophisticated and advanced devices with multiple independent information channels,which may provide technical assistance for digital EM environment reproduction.

关键词： basis vector control reprogrammable metasurface dynamically-controlled holograms arbitrary polarization state broadband

Simplistic framework of single-pixelprogrammable metasurfaces integrated with a capsuled LED array

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Photonics Research 2024年第5期12卷 884-894页

作者： YUXI LI JIAFU WANG SAI SUI RUICHAO ZHU YAJUAN han HONGYA CHEN XINMIN FU SHAOJIE WANG CUNQIAN FENG shaobo QU Shaanxi Key Laboratory of Artificially-Structured Functional Materials and Devices Air Force Engineering UniversityXi’an 710051China Air and Missile Defense College Air Force Engineering UniversityXi’an 710051China

Coding metasurfaces can manipulate electromagnetic wave in real time with high degree of freedom,the fascinating properties of which enrich the metasurface design with a wide range of application ***,most of the coding metasurfaces are designed based on external excitation framework with the wired electrical or wireless light control devices,thus inevitably causing the interference with electromagnetic wave transmission and increasing the complexity of the metasurface *** this work,a simplistic framework of single-pixel-programmable metasurfaces integrated with a capsuled LED array is proposed to dynamically control electromagnetic *** framework fully embeds the photoresistor in the meta-atom,controlling the LED array to directly illuminate the photoresistor to modulate the phase *** this manner,the complex biasing network is transformed to the universal LED array,which means the physical control framework can be transformed to a software framework,and thus the functions of the metasurface can be freely manipulated by encoding the capsuled LED array avoiding mutual coupling of adjacent meta-atoms in real *** the results verify that the far-field scattering pattern can be customized with this singlepixel-programmable ***,this work provides a universal framework for coding metasurface design,which lays the foundation for metasurface intelligent perception and adaptive modulation.

关键词： surface. transformed mutual

Direct field-to-pattern monolithic design of holographic metasurface via residual encoderdecoder convolutional neural network

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Opto-Electronic Advances 2023年第8期6卷 29-38页

作者： Ruichao Zhu Jiafu Wang Tianshuo Qiu Dingkang Yang Bo Feng Zuntian Chu Tonghao Liu Yajuan han Hongya Chen shaobo Qu Shaanxi Key Laboratory of Artificially-Structured Functional Materials and Devices Air Force Engineering UniversityXi'an 710051China The Academy for Engineering&Technology Fudan UniversityShanghai 200433China

Complex-amplitude holographic metasurfaces(CAHMs)with the flexibility in modulating phase and amplitude profiles have been used to manipulate the propagation of wavefront with an unprecedented level,leading to higher image-reconstruction quality compared with their natural ***,prevailing design methods of CAHMs are based on Huygens-Fresnel theory,meta-atom optimization,numerical simulation and experimental verification,which results in a consumption of computing ***,we applied residual encoder-decoder convolutional neural network to directly map the electric field distributions and input images for monolithic metasurface design.A pretrained network is firstly trained by the electric field distributions calculated by diffraction theory,which is subsequently migrated as transfer learning framework to map the simulated electric field distributions and input *** training results show that the normalized mean pixel error is about 3%on *** verification,the metasurface prototypes are fabricated,simulated and *** reconstructed electric field of reverse-engineered metasurface exhibits high similarity to the target electric field,which demonstrates the effectiveness of our ***,this work provides a monolithic field-to-pattern design method for CAHMs,which paves a new route for the direct reconstruction of metasurfaces.

关键词： metasurface holography complex amplitude deep learning monolithic design

Remotely mind-controlled metasurface via brainwaves

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eLight 2022年第1期2卷 121-131页

作者： Ruichao Zhu Jiafu Wang Tianshuo Qiu Yajuan han Xinmin Fu Yuzhi Shi Xingsi Liu Tonghao Liu Zhongtao Zhang Zuntian Chu Cheng‑Wei Qiu shaobo Qu Shaanxi Key Laboratory of Artificially‑Structured Functional Materials and Devices Air Force Engineering UniversityXi’an 710051ShaanxiChina National Key Laboratory of Science and Technology on Micro/Nano Fabrication Department of Micro/Nano ElectronicsShanghai Jiao Tong UniversityShanghai 200240China Department of Electrical and Computer Engineering Faculty of EngineeringNational University of Singapore4 Engineering Drive 3Singapore 117583Singapore

The power of controlling objects with mind has captivated a popular fascination to human *** possible path is to employ brain signal collecting technologies together with emerging programmable metasurfaces(PM),whose functions or operating modes can be switched or customized via on-site programming or pre-defined ***,most of existing PMs are wire-connected to users,manually-controlled and not ***,we propose the concept of remotely mind-controlled metasurface(RMCM)via *** than DC voltage from power supply or AC voltages from signal generators,the metasurface is controlled by brainwaves collected in real time and transmitted wirelessly from the *** an example,we demonstrated a RMCM whose scattering pattern can be altered dynamically according to the user’s brain waves via *** attention intensity information is extracted as the control signal and a mapping between attention intensity and scattering pattern of the metasurface is *** such a framework,we experimentally demonstrated and verified a prototype of such metasurface system which can be remotely controlled by the user to modify its scattering *** work paves a new way to intelligent metasurfaces and may find applications in health monitoring,5G/6G communications,smart sensors,etc.

关键词： Brainwave Mind-controlled Reprogrammable metasurface Intelligent metasurface