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Microstructural evolution during the progressive transformation-induced plasticity effect in a Fe-0.1C-5Mnmedium manganese steel

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 369-379页

作者： mei Zhang Wenhao Li Yangfei Chen Yang jiang Xiaofei Guo han Dong School of Materials Science and Engineering Shanghai UniversityShanghai 200444China State Key Laboratory of Advanced Special Steel Shanghai UniversityShanghai 200444China

The microstructural evolution of a cold-rolled and intercritical annealed medium-Mn steel(Fe-0.10C-5Mn)was investigated during uniaxial tensile ***-situ observations under scanning electron microscopy,transmission electron microscopy,and X-ray diffraction analysis were conducted to characterize the progressive transformation-induced plasticity process and associated fracture initiation *** findings were discussed with the local strain measurements via digital image *** results indicated that Lüders band formation in the steel was limited to 1.5%strain,which was mainly due to the early-stage martensitic phase transformation of a very small amount of the less stable large-sized retained austenite(RA),which led to localized stress concentrations and strain hardening and further retardation of *** small-sized RA exhibited high stability and progressively transformed into martensite and contributed to a stably extended Portevin-Le Chatelier *** volume fraction of RA gradually decreased from 26.8%to 8.2%prior to *** the late deformation stage,fracture initiation primarily occurred at the austenite/martensite and ferrite/martensite interfaces and the ferrite phase.

关键词： medium-Mn steel retained austenite progressive transformation-induced plasticity effect local strain fracture initiation

Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

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Neural Regeneration Research 2025年第1期20卷 159-173页

作者： Man han Deyang Zeng Wei Tan Xingxing Chen Shuyuan Bai Qiong Wu Yushan Chen Zhen Wei Yufei mei Yan Zeng Brain Science and Advanced Technology Institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to Wuhan University of Science and Technology WuhanHubei ProvinceChina School of Public Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of *** focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic ***,BDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amygdala chronic mild stress chronic social defeat stress corticolimbic system depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area

n-HA晶体及n-HA/PA66复合材料与人皮质骨的定性和定量对比研究

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功能材料 2005年第6期36卷 892-895页

作者：吴兰李玉宝杨维虎张利韩纪梅四川大学分析测试中心纳米生物材料研究中心四川成都610064

用TEM、XRD、FTIR、TGDTA等测试手段对成熟的人股骨皮质骨、纳米羟基磷灰石nHA及nHA/聚酰胺66(PA66)复合材料的形貌、相组成、晶胞参数、微晶尺寸分布、微观应变、特征基团和离子以及组成等进行了定性和定量表征。提出了一种简单易行的... 详细信息

用TEM、XRD、FTIR、TGDTA等测试手段对成熟的人股骨皮质骨、纳米羟基磷灰石nHA及nHA/聚酰胺66(PA66)复合材料的形貌、相组成、晶胞参数、微晶尺寸分布、微观应变、特征基团和离子以及组成等进行了定性和定量表征。提出了一种简单易行的制样方法以获得较为清晰的人骨磷灰石照片。定量比较了人骨与两种材料中磷灰石晶体的结构差异。结果表明,nHA和nHA/PA66均具有较高的仿生性能。nHA和nHA/PA66中磷灰石的结晶度高于人骨磷灰石,晶格较人骨磷灰石完善,晶格畸变程度较人骨磷灰石小,并且两者中水分含量和CO2-3含量均低于人骨。本文的研究对于进一步优化现有的骨修复替代材料和进一步开发更接近于人骨的骨修复替代材料具有重要意义。

关键词：皮质骨纳米羟基磷灰石聚酰胺66 晶体结构

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全程参与式实验教学对学生能力培养的尝试

襄樊职业技术学院学报 2006年第5期5卷 72-73页

作者：韩际梅襄樊职业技术学院医学院湖北襄樊441021

本文论述了在高职医学检验专业中实施全程参与式实验教学的新型实验教学方法,并对其教学效果作出评价。

关键词：全程参与式实验教学综合能力医学检验专业教学方法高等职业院校《临床检验基础》

Modeling and control of a rigid-flexible coupling robot for narrow space manipulations

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Science China Technological Sciences 2025年

作者： Kuangda CHEN Huan ZHAO jiexin ZhanG mei FENG Yiwei WANG jinliang WANG han DING State Key Laboratory of Intelligent Manufacturing Equipment and Technology Huazhong University of Science and Technology Key Laboratory of CNC Equipment Reliability Ministry of Education Jilin University School of Medical Equipment Science and Engineering Huazhong University of Science and Technology

Narrow space manipulations are crucial for equipment maintenance, as they eliminate the need for disassembly, thus reducing costs and increasing efficiency. Cable-driven flexible robots possess exceptional capabilities in maneuvering through narrow spaces, thanks to their interaction compliance and distal dexterity. However, their inherent low stiffness causes a decline in the location accuracy of the robot and could even lead to manipulation failure. To address this challenge, this paper proposes a novel type of rigid-flexible coupling robot, which increases the stiffness of the robot while ensuring the reachability within a narrow space. To achieve high-accuracy location in a narrow space, kinematic and control methods are proposed. Specifically,the robot forward kinematics are uniformly represented, and the closed-form inverse kinematics solution is derived. Furthermore, in cases where the robot?s structure fails to align with Pieper?s solution, a two-stage search strategy is utilized to solve the inverse kinematics, resulting in a high success rate of 99.1%. Based on the proposed kinematics, a rigid-dominated control method is then proposed to facilitate localization and pose alignment of target objects in narrow spaces. The practical comparative experiments show that the proposed robot has the capability of high accuracy control in narrow spaces.

关键词：

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磁性壳聚糖微球对牛血清白蛋白的吸附性能

物理化学学报 2007年第10期23卷 1583-1588页

作者：朱晨华沈鹤柏徐瑞云王皓月韩继美上海师范大学生命与环境科学学院上海200234 上海应用技术学院化学工程系上海200235

在微乳液体系中,以戊二醛为交联剂制备了磁性壳聚糖纳米粒子(Fe2O3-CS).采用透射电子显微镜(TEM)、红外光谱(IR)、振动样品磁强计(VSM)等手段对纳米粒子进行表征.结果表明,纳米粒子的粒径在40nm左右,分散性良好,具有较好的磁响应性能.... 详细信息

在微乳液体系中,以戊二醛为交联剂制备了磁性壳聚糖纳米粒子(Fe2O3-CS).采用透射电子显微镜(TEM)、红外光谱(IR)、振动样品磁强计(VSM)等手段对纳米粒子进行表征.结果表明,纳米粒子的粒径在40nm左右,分散性良好,具有较好的磁响应性能.以碳二亚胺(EDC)为活化剂,研究了Fe2O3-CS纳米粒子对牛血清白蛋白(BSA)分子的吸附性能,并使用原子力显微镜(AFM)、紫外分光光度计(UV)进行表征.结果表明,Fe2O3-CS粒子对BSA的吸附大致符合Langmuir吸附模型,298K时饱和吸附量约为250mg·g-1,吸附常数为0.007L·mg-1.将BSA-粒子分散在不同pH的缓冲溶液中,研究BSA-粒子复合物的稳定性.用聚丙烯酰氨凝胶电泳(SDS-PAGE)对结果进行表征,发现在碱性条件下,BSA分子能从磁性粒子表面脱附下来.

关键词：壳聚糖磁性微乳液牛血清白蛋白吸附

纳米羟基磷灰石/壳聚糖复合骨修复材料的共沉淀法制备及其性能表征

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功能材料 2005年第3期36卷 441-444页

作者：张利李玉宝魏杰左奕韩纪梅吴兰王学江四川大学分析测试中心纳米生物材料研究中心四川成都610064

通过共沉淀法制备了纳米羟基磷灰石/壳聚糖复合骨修复材料,并采用 TEM、IR、XRD、TGA 及万能材料试验机等手段对材料进行分析表征,还通过对材料的燃烧试验研究了复合材料中两相间的分散均匀性。结果表明:复合材料中的羟基磷灰石为类似... 详细信息

通过共沉淀法制备了纳米羟基磷灰石/壳聚糖复合骨修复材料,并采用 TEM、IR、XRD、TGA 及万能材料试验机等手段对材料进行分析表征,还通过对材料的燃烧试验研究了复合材料中两相间的分散均匀性。结果表明:复合材料中的羟基磷灰石为类似于自然骨矿物相的弱结晶含碳酸纳米晶体,并均匀分散于有机相壳聚糖中;复合后壳聚糖在 1655cm-1的酰胺Ⅰ谱带和 1599cm-1 的—NH2 吸收峰均向低波数方向移动,暗示复合材料中两相间发生了相互作用。复合材料的力学性能较之两种单组分材料有明显的改善,当纳米羟基磷灰石/壳聚糖重量比为 70/30 时,复合材料的抗压强度最高,达120MPa左右,可满足骨组织修复与替代材料的要求。

关键词：纳米羟基磷灰石壳聚糖复合材料共沉淀

襄阳职业技术学院医学检验技术专业学生技能竞赛实践与研究

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襄阳职业技术学院学报 2018年第5期17卷 19-21页

作者：孙莉韩际梅襄阳职业技术学院医学院湖北襄阳441021

文章结合襄阳职业技术学院医学检验技术专业多年来的校内专业技能竞赛和近两年参加的全国高职高专院校医学检验技能大赛,通过不断摸索、总结、改革与实践,探讨医学检验技术专业如何组织与实施各级专业技能竞赛,以促进专业技能型人才的... 详细信息

文章结合襄阳职业技术学院医学检验技术专业多年来的校内专业技能竞赛和近两年参加的全国高职高专院校医学检验技能大赛,通过不断摸索、总结、改革与实践,探讨医学检验技术专业如何组织与实施各级专业技能竞赛,以促进专业技能型人才的培养。

关键词：医学检验技能竞赛实践教学

高职医学检验技术专业技能考核与评价标准的重构与实践

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襄阳职业技术学院学报 2018年第3期17卷 41-43页

作者：韩际梅孙莉襄阳职业技术学院医学院湖北襄阳441021

医学检验技术是一门综合性、技术性、实践性很强的学科,要求检验工作者除掌握丰富的理论知识外,还必须具有娴熟的实验操作技能。因此,在人才培养过程中,加强实践性环节的教学和操作技能的考核与评价,已成为医学检验技术专业教学的重点... 详细信息

医学检验技术是一门综合性、技术性、实践性很强的学科,要求检验工作者除掌握丰富的理论知识外,还必须具有娴熟的实验操作技能。因此,在人才培养过程中,加强实践性环节的教学和操作技能的考核与评价,已成为医学检验技术专业教学的重点。文章以全国检验技能大赛为纲领,对高职医学检验技术专业操作技能考核与评价标准进行了重新构建,并应用于教学实践,取得了良好效果。

关键词：高职医学检验全国检验技能大赛操作技能考核与评价标准