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Genes & Diseases 2024年第4期11卷 57-60页

作者： Shaolong hao Yu Ji Weixuan Pan hao Sun Fang Nie Jonathan Ray Warren Yuchuan Ding Wei han Department of General Surgery Beijing Luhe HospitalCapital Medical UniversityTongzhouBeijing 101149China Department of Central Laboratory Beijing Luhe HospitalCapital Medical UniversityTongzhouBeijing 101149China Department of Neurosurgery Wayne State University School of MedicineJohn D.Dingell VA Medical CenterDetroitMI 48201USA

Pancreatic cancer is one of the most aggressive malignant tumors of the digestive *** node metastasis(LNM),as the main way of invasion and metastasis,can occur in the early stage of pancreatic cancer and be considered... 详细信息

关键词： metastasis cancer invasion

Magnetometer-only linear attitude estimation for bias momentum pico-satellite

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2010年第6期11卷 455-464页

作者： Ke han hao WANG Zhong-he JIN Department of Information Science and Electronic Engineering Zhejiang University Hangzhou 310027 China

Satellite attitude information is essential for pico-satellite applications requiring light-weight,low-power,and fast-computation *** objective of this study is to provide a magnetometer-only attitude estimation method for a low-altitude Earth orbit,bias momentum *** on two assumptions,the spacecraft spherical symmetry and damping of body rates,a linear kinematics model of a bias momentum satellite's pitch axis is derived,and the linear estimation algorithm is *** algorithm combines the linear Kalman filter(KF) with the classic three-axis attitude determination method(TRIAD).KF is used to estimate satellite's pitch axis orientation,while TRIAD is used to obtain information concerning the satellite's three-axis *** tests confirmed that the algorithm is suited to the time-varying model errors resulting from both *** estimate result keeps tracking satellite attitude motion during all damping,stable,and free rotating control *** with nonlinear algorithms,such as extended Kalman filer(EKF) and square root unscented Kalman filer(SRUKF),the algorithm presented here has an almost equal performance in terms of convergence time and estimation accuracy,while the consumption of computing resources is much lower.

关键词： Pico-satellite Attitude estimation Bias momentum Magnetometer Kalman filter(KF)

Fluorescent probes and functional materials for biomedical applications

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Frontiers of Chemical Science and Engineering 2022年第10期16卷 1425-1437页

作者： Xi-Le Hu Hui-Qi Gan Fan-De Meng Hai-hao han De-Tai Shi Shu Zhang Lei Zou Xiao-Peng He Tony D.James Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering Feringa Nobel Prize Scientist Joint Research CenterSchool of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai 200237China Department of Chemistry University of BathBath BA27AYUK Liver Cancer Institute Zhongshan Hospitaland Key Laboratory of Carcinogenesis and Cancer Invasion(Ministry of Education)Fudan UniversityShanghai 200032China School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiang 453007China School of Materials Science and Engineering Jingdezhen Ceramic InstituteJingdezhen 333403China

Due to their simplicity in preparation,sensitivity and selectivity,fluorescent probes have become the analytical tool of choice in a wide range of research and industrial fields,facilitating the rapid detection of chemical substances of interest as well as the study of important physiological and pathological processes at the cellular *** addition,many long-wavelength fluorescent probes developed have also proven applicable for in vivo biomedical applications including fluorescenceguided disease diagnosis and theranostics(e.g.,fluorogenic prodrugs).Impressive progresses have been made in the development of sensing agents and materials for the detection of ions,organic small molecules,and biomacromolecules including enzymes,DNAs/RNAs,lipids,and carbohydrates that play crucial roles in biological and disease-relevant ***,we highlight examples of fluorescent probes and functional materials for biological applications selected from the special issues“Fluorescent Probes”and“Molecular Sensors and Logic Gates”recently published in this journal,offering insights into the future development of powerful fluorescence-based chemical tools for basic biological studies and clinical translation.

关键词： fluorescent probes imaging cell biomedicine biomolecules

Deep eutectic solvent-driven self-assembly of metal mercaptide complexes with enzyme-mimicking activities for detection of uric acid through one-step cascade catalytic reaction

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Green Chemical Engineering 2024年第1期5卷 75-84页

作者： Jean Claude Munyemana Jia Chen Xin Li Yangxia han hao Tang Hongdeng Qiu CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou730000China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing100039China Department of Pharmacy Gansu Provincial HospitalLanzhou730000China

This work presents a generic strategy to create a series of metal mercaptides complexes via coordination selfassembly between transition metals(Mn,Cu,Co,Fe,and Ni)and cysteine(Cys)by forming the sulfur-metal *** strategy involves dissolving metal chlorides and Cys into deep eutectic solvents(DES),followed by the precipitation of metal mercaptides complexes(such as Cys-Mn)by adding water as an antisolvent,where DES serves as the solvent,shape directing,and capping agent,thereby preventing the formation of other metal ***,the prepared complexes possess both laccase and peroxidase-like properties,allowing the design of a technique for the detection of L-3,4-dihydroxyphenylalanine(L-DOPA)and uric acid,*** prepared Cys-Mn can linearly oxidize L-DOPA with its concentrations from 0.1 to 130μM and the detection limit was calculated to be 75.5 n ***,the Cys-Mn can mimic the activity of peroxidase towards oxidization of o-phenylenediamine at neutral p H,allowing single-step and one-pot cascade reactions for visual and fluorometric measurements of uric acid(UA)that could work in the range of 0.2-500μM UA with a detection limit of 0.06μM and 0.054μМ,*** assay was successful in detecting UA in serum and urine samples with relative standard deviation(RSD)ranging from 7.3%to 10.2%and 3.0%-8.5%respectively,suggesting that it may prove useful in medical diagnostic testing.

关键词： Metal-mercaptides Deep eutectic solvents Self-assembly Peroxidase-mimic catalyst Uric acid detection

地面逆向拼装技术在幕墙支撑钢结构安装中的应用

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建筑技术开发 2024年第8期51卷 9-11页

作者：盛长泉耿琳韩皓亮张晓峰马志远中国建筑第二工程局有限公司山东烟台265700

地面逆向拼装技术在幕墙支撑钢结构安装中的应用已成为当前建筑领域的研究热点。以该技术为切入点,系统阐述了幕墙支撑钢结构安装的关键步骤和技术要点。介绍了项目的概况,详细描述了幕墙支撑钢结构的安装流程,包括从曲面网格节点的构... 详细信息

地面逆向拼装技术在幕墙支撑钢结构安装中的应用已成为当前建筑领域的研究热点。以该技术为切入点,系统阐述了幕墙支撑钢结构安装的关键步骤和技术要点。介绍了项目的概况,详细描述了幕墙支撑钢结构的安装流程,包括从曲面网格节点的构造设计到加工,再到悬挂段施工和整体提升,全面展现了地面逆向拼装技术在实际工程中的应用。

关键词：地面逆向拼装技术幕墙支撑钢结构安装曲面网格节点悬挂段施工整体提升

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粉煤灰的烧结动力学和烧结特性

新型建筑材料 2024年第6期51卷 61-66,93页

作者：惠涛时启林杨超张雪晶韩浩周明源胡思佳陕西建材科技集团股份有限公司陕西西安710018

以粉煤灰为原料,通过高温热膨胀仪研究了粉煤灰烧结速率与升温速率的变化规律以及收缩率与烧结活化能的关系。考察了烧结粉煤灰试样体积密度、吸水率、抗折强度和气孔率与温度的变化。通过XRD和SEM分析了温度对矿相和微观结构的影响。... 详细信息

以粉煤灰为原料,通过高温热膨胀仪研究了粉煤灰烧结速率与升温速率的变化规律以及收缩率与烧结活化能的关系。考察了烧结粉煤灰试样体积密度、吸水率、抗折强度和气孔率与温度的变化。通过XRD和SEM分析了温度对矿相和微观结构的影响。结果表明:烧结速率与升温速率呈正比,升温速率越大越有利于烧结;烧结活化能随收缩率的增大先减小后增大,最小值出现在收缩率为4%时。此外,1200℃烧制的粉煤灰综合性能最优,体积密度2.16 g/cm^(3),吸水率0.36%,抗折强度56.06 MPa,气孔率0.77%。

关键词：粉煤灰烧结活化能烧结速率物相演变微观结构

Abating transport GHG emissions by hydrogen fuel cell vehicles： Chances for the developing world

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Frontiers in Energy 2018年第3期12卷 466-480页

作者： han hao Zhexuan MU Zongwei LIU Fuquan Zhao State Key Laboratory of Automotive Safety and Energy ChinaAutomotive Energy Research Center Tsinghua University Beijing100084 China State Key Laboratory of Automotive Safety and Energy TsinghuaUniversity Beijing 100084 China

Fuel cell vehicles, as the most promising clean vehicle technology for the future, represent the major chances for the developing world to avoid high-carbon lock-in in the transportation sector. In this paper, by taking China as an example, the unique advantages for China to deploy fuel cell vehicles are reviewed. Subsequently, this paper analyzes the greenhouse gas （GHG） emissions from 19 fuel cell vehicle utilization pathways by using the life cycle assessment approach. The results show that with the current grid mix in China, hydrogen from water electro- lysis has the highest GHG emissions, at 3.10 kgCO2/km, while by-product hydrogen from the chlor-alkali industry has the lowest level, at 0.08 kgCO2/krn. Regarding hydrogen storage and transportation, a combination of gas-hydrogen road transportation and single compression in the refueling station has the lowest GHG emissions. Regarding vehicle operation, GHG emissions from indirect methanol fuel cell are proved to be lower than those from direct hydrogen fuel cells. It is recommended that although fuel cell vehicles are promising for the developing world in reducing GHG emissions, the vehicle technology and hydrogen production issues should be well addressed to ensure the life-cycle low-carbon performance.

关键词： hydrogen fuel cell vehicle life cycle assessment energy consumption greenhouse gas (GHG) emissions China

基于深度迁移学习的动态频谱快速适配抗干扰方法

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信息对抗技术 2024年第1期3卷 33-45页

作者：李思达徐逸凡刘杰林凡迪韩昊易剑波徐煜华陆军工程大学通信工程学院江苏南京210000 海南宝通实业公司海南海口570100

机器学习逐渐发展成为一种成熟强大的技术工具,并被广泛应用于无线通信抗干扰领域。其中,较为典型的有基于深度强化学习的抗干扰方法,通过与动态、不确定通信环境的不断交互来学习最优用频策略,有效解决动态频谱接入抗干扰的问题。然而... 详细信息

机器学习逐渐发展成为一种成熟强大的技术工具,并被广泛应用于无线通信抗干扰领域。其中,较为典型的有基于深度强化学习的抗干扰方法,通过与动态、不确定通信环境的不断交互来学习最优用频策略,有效解决动态频谱接入抗干扰的问题。然而,由于外界电磁频谱空间复杂、干扰模式样式动态多变,从头开始学习复杂的抗干扰通信任务往往时效性差,导致学习效率和通信性能显著下降。针对上述问题,提出基于深度迁移学习的动态频谱快速适配抗干扰方法。首先,通过构建预训练模型对已知干扰模式进行学习;其次,使用卷积神经网络提取现实场景下的感知频谱数据,重用过往经验优先启动加速适配;最后,运用微调策略辅助强化学习实施在线抗干扰信道接入。仿真结果表明,相较于传统强化学习算法,所提方法能够有效加快算法收敛速度,提升通信设备抗干扰性能。

关键词：动态频谱抗干扰深度迁移学习强化学习快速适配

Pico-satellite Autonomous Navigation with Magnetometer and Sun Sensor Data

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Chinese Journal of Aeronautics 2011年第1期24卷 46-54页

作者： han Ke WANG hao TU Binjie JIN Zhonghe Department of Information Science and Electronic Engineering Zhejiang University Hangzhou 310027 China

This article presents a near-Earth satellite orbit estimation method for pico-satellite applications with light-weight and low-power requirements. The method provides orbit information autonomously from magnetometer and sun sensor, with an extended Kalman filter （EKF）. Real-time position/velocity parameters are estimated with attitude independently from two quantities： the measured magnitude of the Earth’s magnetic field, and the measured dot product of the magnetic field vector and the sun vector. To guarantee the filter’s effectiveness, it is recommended that the sun sensor should at least have the same level of accuracy as magnetometer. Furthermore, to reduce filter’s computation expense, simplification methods in EKF’s Jacobian calculations are introduced and testified, and a polynomial model for fast magnetic field calculation is developed. With these methods, 50% of the computation expense in dynamic model propagation and 80% of the computation burden in measurement model calculation can be reduced. Tested with simulation data and compared with original magnetometer-only methods, filter achieves faster convergence and higher accuracy by 75% and 30% respectively, and the suggested simplification methods are proved to be harmless to filter’s estimation performance.

关键词： pico-satellite autonomous navigation orbit estimation magnetometer Kalman filter

Short-term prediction for chaotic time series based on photonic reservoir computing using VCSEL with a feedback loop

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Photonics Research 2024年第6期12卷 1222-1230页

作者： XINGXING GUO hanXU ZHOU SHUIYING XIANG QIAN YU YAHUI ZhanG YANAN han TAO WANG YUE hao State Key Laboratory of Integrated Service Networks Xidian UniversityXi'an 710071China State Key Discipline Laboratory of Wide Bandgap Semiconductor Technology School of MicroelectronicsXidian UniversityXi'an 710071China

Chaos,occurring in a deterministic system,has permeated various fields such as mathematics,physics,and life ***,the prediction of chaotic time series has received widespread attention and made signifi-cant ***,many problems,such as high computational complexity and difficulty in hardware im-plementation,could not be solved by existing *** overcome the problems,we employ the chaotic system of a vertical-cavity surface-emitting laser(VCSEL)mutual coupling network to generate chaotic time series through optical system simulation and experimentation in this ***,a photonic reservoir com-puting based on VCSEL,along with a feedback loop,is proposed for the short-term prediction of the chaotic time *** relationship between the prediction difficulty of the reservoir computing(RC)system and the differ-ence in complexity of the chaotic time series has been studied with ***,the attention coefficient of injection strength and feedback strength,prediction duration,and other factors on system perfor-mance are considered in both simulation and *** use of the RC system to predict the chaotic time series generated by actual chaotic systems is significant for expanding the practical application scenarios of the RC.

关键词： loop chaotic prediction