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Optical coherence tomography angiography metrics in different stages of diabetic macular edema

Eye and Vision 2024年第3期10卷 13-20页

作者： Ruyi han Ruowen gong Wei Liu Gezhi Xu Eye Institute and Department of Ophthalmology Eye and ENT Hospital of Fudan University83 Fenyang RoadShanghai200031People’s Republic of China Key Laboratory of Visual Impairment and Restoration Fudan UniversityShanghaiPeople’s Republic of China Key Laboratory of Myopia(Fudan University) Chinese Academy of Medical SciencesNational Health CommissionShanghaiPeople’s Republic of China

Background To investigate the optical coherence tomography angiography(OCTA)characteristics of diabetic macular edema(DME)at different *** This study was a cross-sectional *** diagnosed with DME were *** was classified into early,advanced,and severe *** vessel density(VD)in the superficial vascular plexus(SVP),deep vascular plexus(DVP)and foveal avascular zone(FAZ)parameters,including FAZ area,FAZ perimeter,acircularity index and foveal VD in a 300-μm-wide region around the FAZ(FD-300),were calculated by the AngioVue software.A multivariate generalized estimating equation was used to evaluate the associations between visual acuity and OCTA *** Ninety-two eyes from 74 patients with DME were included in this *** to early(P=0.006)and advanced DME(P=0.003),the acircularity index was higher in severe *** whole and parafoveal VD in the DVP decreased in eyes with severe DME compared to early DME(P=0.018,P=0.005,respectively)and advanced DME(P=0.035,P=0.012,respectively).In the multivariate generalized estimating equation,DME severity,FAZ area and foveal thickness were positively associated with worse visual acuity(P=0.001,P=0.007 and P=0.001,respectively).Conclusion Compared to early and advanced DME,severe DME showed increased irregularity in the FAZ and more extensive vessel damage in the *** severity level of DME,larger FAZ area,and increased foveal thickness could be risk factors for poor visual *** registration The protocol was published in the Chinese Clinical Trial Registry(ChiCTR2000033082).

关键词： Optical coherence tomography angiography Diabetic macular edema Vessel density Acircularity index

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Significantly improved photocatalysis-self-Fenton degradation performance over g-C3N4 via promoting Fe(Ⅲ)/Fe(Ⅱ)cycle

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Rare Metals 2022年第7期41卷 2429-2438页

作者： Le Chen Xin-Xia He Ze-han gong Jia-Lian Li Yang Liao Xiao-Ting Li Jun Ma College of Chemistry and Materials Science Sichuan Normal UniversityChengdu 610068China Department of Science and Technology Sichuan Normal UniversityChengdu 610068China Key Laboratory of Land Resources Evaluation and Monitoring in Southwest Ministry of EducationChengdu 610068China

Photocatalysis-self-Fenton system,i.e.,photo-catalytic H_(2)O_(2)generation and utilization in situ for OH radials production to remove organic pollutants with high-fluent degradation and mineralization performance pos-sesses such advantages as cleanliness,efficiency and ***,its degradation activity always suffers from the Fe(Ⅲ)/Fe(Ⅱ)*** this reason,graphitic carbon interface-modified g-C_(3)N_(4)(CUCN)was fabricated to remarkably improve photocatalysis-self-Fenton degra-dation *** experiment results indicated that CUCN-2%photocatalyst,in which the loading percentage of graphitic carbon was 2%,demonstrated the optimum degradation performance among all the *** mineralization degree for RhB in 3 h over CUCN-2%reached 63.77%,nearly 3.35-fold higher than the pristine g-C_(3)N_(4).The significantly improved mineralization efficiency was ascribed to the promoted Fe(Ⅲ)/Fe(Ⅱ)cycle by photogenerated electrons,which leading to the higher utilization efficiency of H_(2)O_(2)through Fenton reaction,thereby producing more hydroxyl *** is anticipated that our work could provide new insights for the design of photocatalysis-self-Fenton system with exceptional degradation performance for actual photocat-alytic applications.

关键词： g-C_(3)N_(4) Photocatalysis-self-Fenton degradation Fe(Ⅲ)/Fe(Ⅱ)cycle Interface modification Graphitic carbon

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Discriminative explicit instance selection for implicit discourse relation classification

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Frontiers of Computer Science 2024年第4期18卷 129-138页

作者： Wei SONG Hongfei han Xu han Miaomiao CHENG Jiefu gong Shijin WANG Ting LIU Information Engineering College Capital Normal UniversityBeijing 100048China iFLYTEK AI Research Institute Hefei 230088China Research Center for Social Computing and Information Retrieval Harbin Institute of TechnologyHarbin 150006China

Discourse relation classification is a fundamental task for discourse analysis,which is essential for understanding the structure and connection of *** discourse relation classification aims to determine the relationship between adjacent sentences and is very challenging because it lacks explicit discourse connectives as linguistic cues and sufficient annotated training *** this paper,we propose a discriminative instance selection method to construct synthetic implicit discourse relation data from easy-to-collect explicit discourse *** expanded instance consists of an argument pair and its sense *** introduce the argument pair type classification task,which aims to distinguish between implicit and explicit argument pairs and select the explicit argument pairs that are most similar to natural implicit argument pairs for data *** also propose a simple label-smoothing technique to assign robust sense labels for the selected argument *** evaluate our method on PDTB 2.0 and PDTB *** results show that our method can consistently improve the performance of the baseline model,and achieve competitive results with the state-of-the-art models.

关键词： discourse analysis PDTB discourse relation implicit discourse relation classification data expansion

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Mechanistic studies on peroxymonosulfate activation by g-C3N4 under visible light for enhanced oxidation of light-inert dimethyl phthalate

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Chinese Journal of Catalysis 2020年第2期41卷 322-332页

作者： Lijie Xu Lanyue Qi Yang Sun han gong Yiliang Chen Chun Pei Lu Gan College of Biology and the Environment Nanjing Forestry UniversityNanjing 210037JiangsuChina College of Marine Sciences South China Agricultural UniversityGuangzhou 510642GuangdongChina Guangdong Province Key Laboratory of Durability for Marine Civil Engineering School of Civil EngineeringShenzhen UniversityShenzhen 518060GuangdongChina College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037JiangsuChina

Excitation of metal-free graphitic carbon nitride(g-C3N4) under visible light can successfully achieve efficient activation of peroxymonosulfate(PMS). Synergistic effects and involved mechanism were systematically investigated using a light-inert endocrine disrupting compound, dimethyl phthalate(DMP), as the target pollutant. Under visible light irradiation, DMP could not be degraded by direct g-C3 N4-mediated photocatalysis, while in the presence of PMS, the dominant radicals were converted from ·O2 to SO4·– and ·OH, resulting in effective DMP degradation and mineralization. Results showed that higher dosage of PMS or g-C3 N4 could increase the activation amount of PMS and corresponding DMP degradation efficiency, but the latter approach was more productive in terms of making the most of PMS. High DMP concentration hindered effective contact between PMS and g-C3 N4, but could provide efficient use of PMS. Higher DMP degradation efficiency was achieved at p H lower than the point of zero charge(5.4). Based on intermediates identification, the DMP degradation was found mainly through radical attack(·OH and SO4·–) of the benzene ring and oxidation of the aliphatic chains.

关键词： Graphitic carbon nitride Visible light Peroxymonosulfate Dimethyl phthalate Activation Degradation

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Effect of Mo and cold forging deformation on strength and ductility of cobalt-based alloy L605

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Journal of Iron and Steel Research International 2024年第7期31卷 1811-1823页

作者： Zhong-lin Wang Zhi-hua gong Quan Li han-sheng Bao School of Materials and Metallurgy Inner Mongolia University of Science and TechnologyBaotou 014017Inner MongoliaChina Institute of Special Steels Central Iron and Steel Research Institute Co.Ltd.Beijing 100081China

Mo element was added to cobalt-based alloy L605,and cold forging deformation was *** effects of the addition and cold forging deformation on the microstructure and mechanical properties of the alloy were studied by thermodynamic calculation,electron backscatter diffraction,transmission electron microscopy,and X-ray *** stacking fault energy(SFE)of the alloy decreased after the addition,and the formation of stacking faults and intersections were promoted to improve the strength and *** tensile strength of the alloy with Mo increased from 1190 to 1702 MPa after 24%cold deformation,producing significant work *** strengthening mechanism is strain-induced martensitic transformation(SIMT)and deformation *** alloy,combined with Mo and after 24%deformation,had both high strength and ductility in comparison with the original cobalt-based alloy *** is attributed to the lower SFE which caused the increase in stacking fault *** the tensile process,theε-hcp phase was easily generated at the stacking fault to reduce the stress concentration and increase the *** SIMT by adjusting the density of stacking faults can improve the mechanical properties of cobalt-based ***ε-hcp phase,the interaction between deformation twins and dislocations,and the interaction between e-hcp phases during cold forging deformation caused local stress concentration,lowering ductility and toughness.

关键词： Cobalt-based alloy-Stacking fault energy Strain-induced martensitic transformation Deformation twin Cold forging deformation

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Synthesis of T-Extended Carbazoles via One-Pot C-c Coupling and Chlorination Promoted by FeCl3

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Chinese Journal of Chemistry 2020年第12期38卷 1538-1544页

作者： Yang Qian Jia Shang Zhen-Hua Lyu Xin Huang Ai-jiao Guan Li-Jin Xu han-Yuan gong Department of Chemistry Renmin University of ChinaZhongguancundajie 59Beijing 100872China College of Chemistry Beijing Normal UniversityXinjiekouwaidajie 19Beijing 100875China Institute of Chemistry Chinese Academy of SciencesZhongguancunbeiyijie 2Beijing 100190China

of main observation and conclusion A facile synthesis,functionalization,and emission property of N-doped carbon-rich halogenated compound 3,6,12,15-tetrachloro-9-phenyl-9H-tetrabenzo[a,c,g#i]carbazole(ClCbz)was ***-effective FeCI3 catalyst serves to break eight C—H bonds of 1,2,3,4,5-pentaphenylpyrrole(1)and subsequently construct two C—C and four C—Cl bonds in one pot with a high yield of up to 75%.

关键词： bonds conclusion facile

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PRX1-positive mesenchymal stem cells drive molar morphogenesis

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International Journal of Oral Science 2024年第2期16卷 293-305页

作者： Xiaoqiao Xu Xuyan gong Lei Zhang han Zhang Yao Sun Department of Implantology Stomatological Hospital and Dental School of Tongji UniversityShanghai Engineering Research Center of Tooth Restoration and RegenerationShanghaiChina

Mammalian teeth,developing inseparable from epithelial-mesenchymal interaction,come in many shapes and the key factors governing tooth morphology deserve to be *** merging single-cell RNA sequencing analysis with lineage tracing models,we have unearthed a captivating correlation between the contrasting morphology of mouse molars and the specific presence of PRX1^(+)cells within *** PRX1^(+)cells assume a profound responsibility in shaping tooth morphology through a remarkable divergence in dental mesenchymal cell *** into the mechanisms,we have discovered that Wnt5a,bestowed by mesenchymal PRX1^(+)cells,stimulates mesenchymal cell proliferation while orchestrating molar morphogenesis through WNT signaling *** loss of Wnt5a exhibits a defect phenotype similar to that of *** addition of WNT5A can successfully reverse the inhibited cell proliferation and consequent deviant appearance exhibited in Prx1-deficient tooth *** findings bestow compelling evidence of PRX1-positive mesenchymal cells to be potential target in regulating tooth morphology.

关键词： Wnt5a mesenchymal inhibited

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Policy Network-Based Dual-Agent Deep Reinforcement Learning for Multi-Resource Task Offloading in Multi-Access Edge Cloud Networks

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China Communications 2024年第4期21卷 53-73页

作者： Feng Chuan Zhang Xu han Pengchao Ma Tianchun gong Xiaoxue School of Communications and Information Engineering Chongqing University of Posts and TelecommunicationsChongqing 400065China Institute of Intelligent Communication and Network Security Chongqing University of Posts and TelecommunicationsChongqing 400065China Key Laboratory of Big Data Intelligent Computing Chongqing University of Posts and TelecommunicationsChongqing 400065China School of Information Engineering Guangdong University of TechnologyGuangzhou 510006China

The Multi-access Edge Cloud(MEC) networks extend cloud computing services and capabilities to the edge of the networks. By bringing computation and storage capabilities closer to end-users and connected devices, MEC networks can support a wide range of applications. MEC networks can also leverage various types of resources, including computation resources, network resources, radio resources,and location-based resources, to provide multidimensional resources for intelligent applications in 5/***, tasks generated by users often consist of multiple subtasks that require different types of resources. It is a challenging problem to offload multiresource task requests to the edge cloud aiming at maximizing benefits due to the heterogeneity of resources provided by devices. To address this issue,we mathematically model the task requests with multiple subtasks. Then, the problem of task offloading of multi-resource task requests is proved to be NP-hard. Furthermore, we propose a novel Dual-Agent Deep Reinforcement Learning algorithm with Node First and Link features(NF_L_DA_DRL) based on the policy network, to optimize the benefits generated by offloading multi-resource task requests in MEC networks. Finally, simulation results show that the proposed algorithm can effectively improve the benefit of task offloading with higher resource utilization compared with baseline algorithms.

关键词： benefit maximization deep reinforcement learning multi-access edge cloud task offloading

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Life on the Third Pole

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China Today 2015年第8期64卷 66-69页

作者： gong han

LOOK what I’ve found!"George Schaller exclaimed as he displayed a black caterpillar squirming on his *** particular grub was the eminent American wildlife biologist’s most impressive discovery on his trip to the Qinghai-Tibet *** the way from Yushu to Zadoi the drivers transporting Schaller’s team stopped at a section of road that was writhing with these *** got out,placed the larvae carefully in buckets

关键词：寿命三杆西藏高原生物学家野生动物 grub 蠕动

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Zhuzhu and Her Village Library

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China Today 2017年第1期66卷 64-67页

作者： gong han

AFTER being a migrant worker for over 10 years,Wu Lizhu,nicknamed Zhuzhu,returned to her hometown in Lanbiao Village,Jieyang City,Guangdong Province,and set up a library free of charge for local *** was two years *** that,she had spent four years working with a nonprofit organization in Beijing which provided assistance to the children of migrant workers and

关键词：图书馆外来务工人员乡村组织工作揭阳市广东省合作社青少年

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