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Unraveling the nature of sensing in electrostatic mEmS gas sensors

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microsystems & Nanoengineering 2024年第3期10卷 109-117页

作者： Yasser S.Shama Sasan Rahmanian hamza mouharrar Rana Abdelrahman Alaaeldin Elhady Eihab m.Abdel-Rahman Systems Design Engineering University of Waterloo200 University Ave WWaterloo N2L 3G1 ONCanada mechanical Engineering Benha Faculty of EngineeringBenha UniversityBenha 13511Egypt

This paper investigates the fundamental sensing mechanism of electrostatic mEmS gas *** compares among the responsivities of a set of mEmS isopropanol sensors before and after functionalization,and in the presence and absence of electrostatic fields when operated in static and dynamic detection *** the static mode,we found that the sensors do not exhibit a measurable change in displacement due to added *** the other hand,bare sensors showed a clear change in displacement in response to isopropanol *** the dynamic mode,functionalized sensors showed a measurable frequency shift due to the added mass of isopropanol *** the presence of strong electrostatic fields,the measured frequency shift was found to be threefold larger than that in their absence in response to the same concentration of isopropanol *** enhanced responsivity of dynamic detection allows the sensors to measure the vapor mass captured by the functional material,which is not the case for static *** detection of isopropanol by bare sensors in static mode shows that change in the medium permittivity is the primary sensing *** enhanced responsivity of dynamic mode sensors when operated in strong electrostatic fields shows that their sensing mechanism is a combination of a weaker added mass effect and a stronger permittivity *** findings show that electrostatic mEmS gas sensors are independent of the direction of the gravitational field and are,thus,robust to changes in *** is erroneous to refer to them as‘gravimetric’sensors.

关键词： mechanism electrostatic measurable

Experimental and numerical study of effecting core configurations on the static and dynamic behavior of honeycomb plate with aluminum material

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Defence Technology（防务技术） 2024年第9期39卷 177-192页

作者： Nehad Abid Allah hamza Fatima mohammed K.AL-Fatlwe muna Ali Talib Engineering College Al-Qasim Green University51013BabylonIraq Engineering Technical College of Al-Najaf Al-Furat Al-Awsat Technical University(ATU)Najaf54003Iraq

The sandwich panel incorporated a honeycomb core,a widely utilized composite structure recognized as a fundamental classification of composite *** a core resembling a honeycomb,possessing thickness and softness,and is flank by rigid face sheets that sandwich various shapes and *** paper presents an examination of the static and dynamic analysis of lightweight plates made of aluminum honeycomb sandwich *** sandwich plate samples are 300 mm long,and 300 mm wide,the heights of the core have been varied at four values ranging from 10 to 25 *** honeycomb core is manufactured from Aluminum material by using a novel technique namely resistance spot welding(RSW)instead of using adhesive material,which is often used when an industrial flaw is *** optimization based on response surface methodology(RSm)and design of experiment software(DOE)was used to verify the current work.A theoretical examination of the crashworthiness behavior(maximum bending load,maximum deflection)and vibration attributes(natural frequency,damping ratio,transient temporal response)of honeycomb sandwich panels with different design parameters was also carried *** addition,the finite element method-based ANSYS software was used to confirm the theoretical *** findings of the present work showed that the relationship between the natural frequency,core height,and cell size is *** contrast,the relationship between the natural frequency and the thickness of the cell wall is ***,the damping ratio is inversely proportional to the core height and cell size but directly proportional to the thickness of the cell *** study indicates that altering the core height within 10-25 mm leads to a significant increase of 82%in the natural frequency and a notable decrease of 49%in the damping *** findings are based on a specific cell size value of 0.01 m and a cell wall thickness of 0.001 ***,the results indicate

关键词： Honeycomb Load Transient response Free vibration Natural frequency

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Wave Reflection by Rectangular Breakwaters for Coastal Protection

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Fluid Dynamics & materials Processing 2024年第3期20卷 579-593页

作者： Hasna Akarni hamza mabchour Laila El Aarabi Soumia mordane Laboratory of Polymer Physics Mechanical Sciences and MaterialsFaculty of Sciences Ben M’SikHassan II University of CasablancaCasablanca20670Morocco

In this study,we focus on the numerical modelling of the interaction between waves and submerged structures in the presence of a uniform flow *** the same and opposite senses of wave propagation are *** main objective is an understanding of the effect of the current and various geometrical parameters on the reflection *** wave used in the study is based on potential theory,and the submerged structures consist of two rectangular breakwaters positioned at a fixed distance from each other and attached to the bottom of a wave *** numerical modeling approach employed in this work relies on the Boundary Element method(BEm).The results are compared with experimental data to validate the *** findings of the study demonstrate that the double rectangular breakwater configuration exhibits superior wave attenuation abilities if compared to a single rectangular breakwater,particularly at low ***,the study reveals that wave mitigation is more pronounced when the current and wave propagation are coplanar,whereas it is less effective in the case of opposing current.

关键词： Wave current breakwaters Boundary Element method(BEm) reflection coefficient

Exploring the impact of tacrolimus on kidney transplant recipients:insights into immunological outcomes

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Journal of Chinese Pharmaceutical Sciences 2024年第8期33卷 737-750页

作者： Zainab A Abbood Ahmed hamza AL-Shammari Eman m.Jasim Amjad I.Oraibi Department of Pharmacy Kut University CollegeAlkutWasitIraq52001 AL-manara College For medical Science/Department of Pharmacy MisanIraq62001

To minimize graft rejection,it is crucial to reduce *** the present study,we investigated immunological markers in the blood of transplant patients who did not receive *** also assessed alloreactive CD4+CD25+FoxP3+ Tregs both before transplantation and after tacrolimus *** comparative analysis included 50 individuals experiencing early rejection after tacrolimus discontinuation and 100 *** reducing tacrolimus,rejectors exhibited elevated levels of memory CD8+T cells compared to Tregs,while non-rejectors displayed a lower ratio of memory CD4+T cells to *** tacrolimus removal,rejectors showed an increase in naïve T cells and a decrease in effector T *** transplantation,CD4+Treg levels declined,but their anti-donor regulatory function remained consistent in both rejectors and *** correlation revealed an association between acute rejection after tacrolimus discontinuation and the pre-reduction ratio of memory T cells to regulatory T *** indicators identified individuals whose immunosuppression could be safely reduced.

关键词： Tacrolimus Kidney Transplant Immune system Rejection

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modulation of oxidative damage and genotoxicity of biosynthesized zinc oxide nanoparticles via supplementation with modified cinnamaldehyde-loaded chitosan nanoparticles in mice

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Food Science and Human Wellness 2024年

作者： mosaad A.Abdel-Wahhab Aziza A.El-Nekeety Asmaa S.Salman Zeinab K.hamza Engy m.Akl Soher E.Aly Wenyi Kang Department of Food Toxicology & Contaminants， National Research Centre Dokki， Cairo， Egypt Genetic and Cytology Department， National Research Centre Dokki， Cairo， Egypt Department of Fats and Oils， National Research Centre Dokki， Cairo， Egypt National R & D Center for Edible Fungus Processing Technology， Henan University Joint International Research Laboratory of Food & medicine Resource Function Functional Food Engineering Technology Research Center Henan

Synthesis of zinc oxide nanoparticles (Zn-NPs) via green method is an outstanding alternative to conventional/regular methods; however， the safety or toxicity of the biosynthesized ZnO-NPs in vivo is not fully explored. This study was conducted to evaluate the protective efficiency of cinnamaldehyde-loaded chitosan nanoparticles (Cin@CSNPs) against oxidative damage and genotoxicity of zinc oxide nanoparticles (ZnO-NPs) in mice. ZnO-NPs were biosynthesized using the extract of fresh leaves of mentha pulegium L. Cin was extracted from cinnamon essential oil， and was loaded into chitosan nanoparticle (Cin@CSNPs). Both ZnO-NPs， Cin@CSNPs and CSNPs were characterized. The in vitro release of Cin@CSNPs was determined. In the biological study， 6 groups of male Balb/c mice were treated by gavage for 3 weeks as follows， control group， the group received ZnO-NPs (25 mg/kg b.w)， the groups received Cin@CSNPs at low dose (50 mg/kg b.w) or high dose (100 mg/kg b.w)， and the groups received ZnO-NPs plus Cin@CSNPs at the two tested doses. Blood and tissue samples were collected for different biochemical， genetical and histological studies. The particle size of ZnO-NPs， CSNPs， and Cin@CSNPs were (20.78 ± 2.6)， (170.0 ± 3.7)， and (218.23 ± 2.9) nm， and ξ-potential were (32.7 ± 4.6)， (8.32 ± 0.27) and (4.8 ± 0.21)， respectively. ZnO-NPs disturbed the biochemical and oxidative stress indices， AFP， CEA， TNF-α， chromosomal aberrations in somatic and germ cells， and sperm abnormality along with severe pathological changes in the hepatic， renal， and testicular tissues. Cin@CSNPs improved significantly all the parameters tested and the histological picture in a dose-dependent. Therefore， the biosynthesized ZnO-NPs exhibit oxidative damage and genotoxicity， and Cin@CSNPs have potential protective effects against the risks of ZnO-NPs and may be a promising tool to overcome the challenges of using Cin in food and pharmaceuticals applications.

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Precise separation and efficient recovery of Pd(Ⅱ) from high-level liquid waste by XAD-based adsorbents

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Rare metals 2024年第10期43卷 5372-5390页

作者： Hao-Ran Dong Shun-Yan Ning Zeng-Yuan Li Si-Zhi Xu Feng-Tao Hu Feng Gao You-Bin Wang Li-Feng Chen Xiang-Biao Yin Toyohisa Fujita mohammed F.hamza Yue-Zhou Wei School of Resources Environment and MaterialsGuangxi University School of Nuclear Science and Technology University of South China

Efficient separation of palladium (Pd（II）) from high-level liquid waste （HLLW） not only helps the safe disposal of nuclear waste,but also is a vital importan supplement to Pd（II） ***,16 kinds of nove Amberlite XAD resins-based adsorbents were prepared by vacuum impregnation method for the separation of Pd（II）from simulated HLLW,and the mmBT/XAD7HP prepared using 4-methyl-2-mercaptobenzothiazole （mmBT） as ligand and Amberlite XAD7HP resin （XAD7HP） as the carrier was selected as the optimal research *** analysis experiments proved the successful preparation of mmBT/XAD7HP,which exhibited ultrahigh adsorption selectivity for Pd（II）(distribution coefficient （Kd）≥12584.5 ml·g-1,separation factor (SFPd/m)≥2818.4) and superior adsorption capacity(Q≥130.1 mg·g-1).The adsorption kinetics and adsorption isotherms for Pd（II） matched with pseudo-secondorder （PSO） kinetics model and Langmuir model,indicating that the adsorption mode for Pd（II） by mmBT/XAD7 HP was monolayer chemical *** dynamic column experiments showed that mmBT/XAD7 HP achieved efficiently separation of Pd（II） from simulated HLLW,and the recovery rate was nearly 100% The adsorption mechanism was analyzed by Fourier transform infrared spectroscopy （FTIR）,X-ray photoelectron spectroscopy （XPS） and density functional theory（DFT）,and the ultrahigh selectivity of mmBT/XAD7 HP is attributed to the preferred affinity of the soft-N,S donor atoms in mmBT for Pd（II）.mmBT has the shortest frontline molecular orbital energy band gap （HOmO–LUmO） among the four ligands,which makes it easier to become an electron donor to attract Pd2+to participate in ***3-participates in the adsorption to keep charge *** summary,mmBT/XAD7 HP has broad application prospects for the treatment of Pd（II） in HLLW

关键词： Adsorption Column experiments HLLW Palladium XAD

Predicting short-term thromboembolic risk following Roux-en-Y gastric bypass using supervised machine learning

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World Journal of Gastrointestinal Surgery 2024年第4期16卷 1097-1108页

作者： Hassam Ali Faisal Inayat Vishali moond Ahtshamullah Chaudhry Arslan Afzal Zauraiz Anjum hamza Tahir muhammad Sajeel Anwar Dushyant Singh Dahiya muhammad Sohaib Afzal Gul Nawaz Amir H Sohail muhammad Aziz Department of Gastroenterology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Department of Internal medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Department of Internal medicine Saint Peter's University Hospital and Robert Wood Johnson Medical SchoolNew BrunswickNJ 08901United States Department of Internal medicine St.Dominic's HospitalJacksonMS 39216United States Department of Internal medicine Rochester General HospitalRochesterNY 14621United States Department of Internal medicine Jefferson Einstein HospitalPhiladelphiaPA 19141United States Department of Internal medicine UHS Wilson Medical CenterJohnsonNY 13790United States Division of Gastroenterology Hepatology and MotilityThe University of Kansas School of MedicineKansasKS 66160United States Department of Internal medicine Louisiana State University HealthShreveportLA 71103United States Department of Surgery University of New Mexico School of MedicineAlbuquerqueNM 87106United States Department of Gastroenterology and Hepatology The University of ToledoToledoOH 43606United States

BACKGROUND Roux-en-Y gastric bypass(RYGB)is a widely recognized bariatric procedure that is particularly beneficial for patients with class III *** aids in significant weight loss and improves obesity-related medical *** its effectiveness,postoperative care still has *** evidence shows that venous thromboembolism(VTE)is a leading cause of 30-d morbidity and mortality after ***,a clear unmet need exists for a tailored risk assessment tool for VTE in RYGB *** To develop and internally validate a scoring system determining the individualized risk of 30-d VTE in patients undergoing *** Using the 2016–2021 metabolic and Bariatric Surgery Accreditation Quality Improvement Program,data from 6526 patients(body mass index≥40 kg/m^(2))who underwent RYGB were analyzed.A backward elimination multivariate analysis identified predictors of VTE characterized by pulmonary embolism and/or deep venous thrombosis within 30 d of *** resultant risk scores were derived from the coefficients of statistically significant *** performance of the model was evaluated using receiver operating curves through 5-fold *** Of the 26 initial variables,six predictors were *** included a history of chronic obstructive pulmonary disease with a regression coefficient(Coef)of 2.54(Pmbosis(Coef 1.61,Pmoglobin A1c>7%(Coef 1.19,Pm that was generated for the model predicting 30-d VTE risk *** risk model's area under the curve(AUC)was 0.79[95%confidence interval(CI):0.63-0.81],showing good discriminatory power,achieving a sensitivity of 0.60 and a specificity of *** training,the same model performed satisfactorily

关键词： Roux-en-Y gastric bypass Venous thromboembolism machine learning Bariatric surgery Predictive modeling

Structure-based discovery of *** phytochemicals as potential inhibitors against monkeypox(mpox)viral protein

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Journal of Biosafety and Biosecurity

Journal of Biosafety and Biosecurity 2024年第3期6卷 157-169页

作者： Ranjan K.mohapatra Ahmed mahal Pranab K.mohapatra Ashish K.Sarangi Snehasish mishra meshari A.Alsuwat Nada N.Alshehri Sozan m.Abdelkhalig mohammed Garout mohammed Aljeldah Ahmad A.Alshehri Ahmed Saif mohammed Abdulrahman Alshahrani Ali S.Alqahtani Yahya A.Almutawif hamza m.A.Eid Faisal m Albaqami mohnad Abdalla Ali A.Rabaan Department of Chemistry Government College of EngineeringKeonjhar 758002OdishaIndia Department of medical Biochemical Analysis College of Health TechnologyCihan University–ErbilErbilKurdistan RegionIraq Department of Chemistry CV Raman Global UniversityBhubaneswarOdishaIndia Department of Chemistry School of Applied SciencesCenturion University of Technology and ManagementBalangirOdishaIndia School of Biotechnology Campus-11KIIT Deemed-to-be-UniversityBhubaneswar 751024OdishaIndia Clinical Laboratory Sciences Department College of Applied Medical SciencesTaif UniversityAl-Taif 21974Saudi Arabia Internal medicine Department King Khalid University Medical CityCollege of MedicineAbha 61481Saudi Arabia Department of Basic medical Sciences College of MedicineAlMaarefa UniversityRiyadhSaudi Arabia Department of Community medicine and Health Care for Pilgrims Faculty of MedicineUmm Al-Qura UniversityMakkah 21955Saudi Arabia Department of Clinical Laboratory Sciences College of Applied Medical SciencesUniversity of Hafr Al BatinHafr Al Batin 39831Saudi Arabia Department of Clinical Laboratory Sciences Faculty of Applied Medical SciencesNajran UniversityNajran 61441Saudi Arabia Department of medical Laboratory Sciences Faculty of Applied Medical SciencesKing Khalid UniversityAbha 61481Saudi Arabia mDepartment of medical Laboratories Technology College of Applied Medical SciencesTaibah UniversityMadinah 41411Saudi Arabia Biology Department College of ScienceIslamic University of MadinahMadinah 42351Saudi Arabia Pediatric Research Institute Children’s Hospital Affiliated to Shandong UniversityJinanShandong 250022China molecular Diagnostic Laboratory Johns Hopkins Aramco HealthcareDhahran 31311Saudi Arabia College of medicine Alfaisal UniversityRiyadh 11533Saudi Arabia Department of Public Health and Nutrition The University of HaripurHaripur 22610Pakistan

Outbreaks of monkeypox(mpox)in over 100 non-endemic countries in 2022 represented a serious global health *** a neglected disease,mpox has become a global public health issue.A42R profilinlike protein from mpox(PDB ID:4QWO)represents a potential new lead for drug development and may interact with various synthetic and natural *** this report,the interaction of A42R profilinlike protein with six phytochemicals found in the medicinal plant Ficus religiosa(abundant in India)was *** on the predicted and compared protein–ligand binding energies,biological properties,IC_(50) values and toxicity,two compounds,kaempferol(C-1)and piperine(C-4),were *** characteristics and quantitative structure–activity relationship(QSAR)of these two compounds were determined,and molecular dynamics(mD)simulations were *** silico examination of the kaempferol(C-1)and piperine(C-4)interactions with A42R profilin-like protein gave best-pose ligandbinding energies of–6.98 and–5.57 kcal/mol,*** predicted IC_(50) of C-1 was 7.63 lm and 82 lm for *** data indicated that kaempferol and piperine are non-mutagenic,and the QSAR data revealed that piperlongumine(5.92)and piperine(5.25)had higher log P values than the other compounds *** simulations of A42R profilin-like protein in complex with C-1 and C-4 were performed to examine the stability of the ligand–protein ***/C and C-4 showed the highest affinity and activities,they may be suitable lead candidates for developing mpox therapeutic *** study should facilitate discovering and synthesizing innovative therapeutics to address other infectious diseases.

关键词： monkeypox mpox Phytochemical molecular docking mD simulation ADmET QSAR

Violence study of healthcare workers and systems in the Caribbean:ViSHWaS-Caribbean study

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World Journal of methodology 2024年第3期14卷 106-118页

作者： Reshon Hadmon Daniella myriam Pierre Akshat Banga Jacques W Clerville Hans mautong Precious Akinsanya Rajat Das Gupta Sama Soliman Tolupe m Hunjah Bamidele A Hunjah Hafeez hamza Ruman Khurshid Qasba Faisal A Nawaz Salim Surani Rahul Kashyap Department of medicine St.George University School of MedicineGrenada FZ818West Indies Department of Research Global Remote Research Scholar ProgramSt PaulMN 55101United States Department of Public Health Cuny Graduate School of Public Health and Health PolicyNew YorkNY 10027United States Department of Internal medicine Sawai Man Singh Medical CollegeJaipur 302004India School of Public Health Georgia State UniversityAtlantaGA 30302United States Department of Sociology and Demography School of HealthUniversidad de Especialidades Espiritu SantoSamborondon 092301Ecuador Department of medicine Holy Name Medical CenterTeaneckNJ 07666United States Department of Epidemiology and Biostatistics University of South CarolinaColumbiaSC 29208United States Department of medicine Pavlov First State Medical University of St PetersburgSankt-Peterburg 197022Russia Department of medicine University of SuffolkIpswich IP41QJUnited Kingdom Department of medicine Unicaf University of ZambiaLusaka 20842Zambia Department of Pharmacy School of PharmacyGirne 99428Cyprus Department of medicine Sher-i-KashmirInstitute of Medical ScienceSrinagar 190011India Department of Psychiatry Al Amal Psychiatric HospitalEmirates Health ServicesDubaiUnited Arab Emirates Department of medicine and Pharmacology Texas A and M UniversityCollege StationTX 77843United States Anesthesiology and Critical Care Mayo ClinicRochesterMN 55905United States Department of Research Wellspan HealthYorkPA 17403United States

BACKGROUND Violence against healthcare workers(HCWs)in the Caribbean continues to prevail yet remains *** aim is to determine the cause,traits,and consequences of violence on HCWs in the *** To determine the cause,traits,and consequences of violence on HCWs in the *** This research adopted an online cross-sectional survey approach,spanning over eight weeks(between June 6th and August 9th,2022).The survey was generated using Research Electronic Data Capture forms and followed a snowballing strategy to contact individuals using emails,social media,text messages,*** regression analysis was performed to evaluate the variables that influence violence,including gender,age,years of experience,institution type,and night shift *** The survey was completed by 225 *** comprised 61%.Over 51%of respondents belonged to the 21 to 35 age ***(n=61),Haiti(n=50),and Grenada(n=31)had the most *** HCWs(49%)worked for government academic institutions,followed by community hospitals(23%).medical students(32%),followed by attending physicians(22%),and others(16%)comprised the most common cadre of *** 39%of the participants reported experiencing violence themselves,and 18%reported violence against colleague(s).Verbal violence(48%),emotional abuse(24%),and physical misconduct(14%)were the most common types of *** 63%of respondents identified patients or their relatives as the most frequent *** logistic regression analyses demonstrated that female gender(OR=2.08;95%CI:1.16-3.76,P=0.014)and higher frequency of night shifts(OR=2.22;95%CI:1.08-4.58,P=0.030)were associated with significantly higher odds of experiencing *** than 50%of HCWs felt less motivated and had decreased job satisfaction post-violent *** A large proportion of HCWS in the Caribbean are exposed to violence,yet the phenomenon remains *** a result,HCWs’job s

关键词： ViSHWaS Healthcare workers Violence Survey Workplace violence Caribbean Cross-sectional study