检索结果-南通市图书馆

Synthesis of different-sized gold nanostars for Raman bioimaging and photothermal therapy in cancer nanotheranostics

引用

中国科学：化学英文版 2017年第9期60卷 1219-1229页

作者： Jie Gao Maria Sanchez-Purra Hao Huang ShunhaoWang Yunan Chen Xuefeng Yu Qian Luo Kimberly hamad-Schifferli Sijin Liu State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences.Beijing 100049 China Department of Engineerfng University of Massachusetts BostonBostonMA 02125United States Institute of Biomedicine and Biotechnology Shenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Department of Mechanical Engineering Massachusetts Institute of TechnologyCambridgeMA 02139United States

Gold nanoparticles(AuNPs) have been attractive for nanomedicine because of their pronounced optical ***,we customerized the methods to synthesize two types of gold nanostars,Au nanostars-1 and Au nanostars-2,which have different spire lengths and optical properties,and also spherical *** to nanospheres,gold nanostars were less toxic to a variety of cells,including *** nanostars-1 and Au nanostars-2 also manifested a similar pattern of tissue distribution upon in vivo administration in mice to that of nanospheres,and but reveled less liver retention than *** to their strong absorption in the near-infrared(NIR),Au nanostars-2 induced a strong hyperthermia effect in vitro upon excitation at 808 nm,and elicited a robust photothermal therapy(PTT) efficacy in ablating tumors in a mouse model of orthotopic breast cancer using 4T1 breast cancer ***,Au nanostars-1 showed a great capability to enhance the Raman signal through surface-enhanced Raman spectroscopy(SERS) in 4T1 *** combined results opened a new avenue to develop Au nanostars for cancer imaging and therapy.

关键词： gold nanoparticle, nanostar, surface plasmon resonance, tissue distribution, toxicity profile

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Differential diagnosis between autism spectrum disorder and other developmental disorders with emphasis on the preschool period

引用

世界儿科杂志:英文版 2023年第8期19卷 715-726页

作者： Taynara Amancio de Lima Patricia Aparecida Zuanetti Marina Estima Neiva Nunes Ana Paula Andrade hamad Department of Neurosciences and Behavioral Sciences Ribeirão Preto Medical SchoolUniversity of São PauloAv.Bandeirantes3900Monte AlegreRibeirão PretoSP14049-900Brazil University Hospital Ribeirão Preto Medical SchoolUniversity of São Paulo(HCFMRP-USP)Ribeirão PretoSPBrazil

Background Neurodevelopmental disorders are a heterogeneous group of conditions that manifest as delays or deviations in the acquisition of expected developmental milestones and behavioral *** spectrum disorder(ASD)is a neurodevelopmental disorder characterized by deficits in communication and social interaction and by repetitive and restricted patterns of behavior,interests and *** aim of this review is to discuss the clinical features of the differential diagnoses of ASD that are prevalent among preschoolers,focusing on their similarities and *** sources The international medical literature search was conducted using PubMed and was revised regarding the subject using single and/or combined keywords as follows:differential diagnosis,preschoolers,diagnostic challenge,attention deficit hyperactivity disorder,intellectual disability,high abilities/giftedness,childhood apraxia of speech,social communication disorder,Landau–Kleffner syndrome,stereotyped movement disorder and excessive screen *** We describe conditions commonly found in clinical practice,taking ASD as a *** addressed converging and divergent aspects of behavior,cognition,communication,language,speech,socialization,and stereotypes for the diagnosis of ASD and other disorders identified as potential differential or comorbid *** The ranking and characterization of symptoms appear to be essential for better understanding the underlying common ground between children with developmental disorders and children with ASD,thus properly diagnosing and directing social,professional,or medication *** detailed discussion adds to the literature since,although ASD differential diagnoses are frequently mentioned and discussed in textbooks and journal articles,they rarely occupy a prominent place as we aimed herein.

关键词： Autism spectrum disorder Clinical features Differential diagnosis Neurodevelopmental disorders Preschool

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Intelligent Traffic Surveillance through Multi-Label Semantic Segmentation and Filter-Based Tracking

引用

Computers, Materials & Continua 2023年第9期76卷 3707-3725页

作者： Asifa Mehmood Qureshi Nouf Abdullah Almujally Saud S.Alotaibi Mohammed hamad Alatiyyah Jeongmin Park Department of Creative Technologies Air UniversityIslamabad44000Pakistan Department of Information Systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Information Systems Department Umm Al-Qura UniversityMakkahSaudi Arabia Department of Computer Science College of Sciences and Humanities in AflajPrince Sattam Bin Abdulaziz UniversityAl-KharjSaudi Arabia Department of Computer Engineering Tech University of KoreaSiheung-siGyeonggi-do15073Korea

Road congestion,air pollution,and accident rates have all increased as a result of rising traffic density andworldwide population *** the past ten years,the total number of automobiles has increased significantly over the *** this paper,a novel method for intelligent traffic surveillance is *** proposed model is based on multilabel semantic segmentation using a random forest classifier which classifies the images into five *** improve the results,mean-shift clustering was applied to the segmented ***,the pixels given the label for the vehicle were extracted and blob detection was applied to mark each *** the validation of each detection,a vehicle verification method based on the structural similarity index is *** tracking of vehicles across the image frames is done using the Identifier(ID)assignment technique and particle ***,vehicle counting in each frame along with trajectory estimation was done for each *** proposed system demonstrated a remarkable vehicle detection rate of 0.83 over Vehicle Aerial Imaging from Drone(VAID),0.86 over AU-AIR,and 0.75 over the Unmanned Aerial Vehicle Benchmark Object Detection and Tracking(UAVDT)dataset during the experimental *** proposed system can be used for several purposes,such as vehicle identification in traffic,traffic density estimation at intersections,and traffic congestion sensing on a road.

关键词： Traffic surveillance multi-label segmentation random forest particle filter computer vision

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Lack of Syndecan-1 produces significant alterations in whole-body composition, metabolism and glucose homeostasis in mice

引用

World Journal of Diabetes 2020年第4期11卷 126-136页

作者： Anil Kumar Jaiswal Mohanraj Sadasivam Susan Aja Abdel Rahim A hamad Department of Pathobiology Johns Hopkins UniversityBaltimoreMD 21205United States Department of Pathology Johns Hopkins UniversitySchool of MedicineBaltimoreMD 21205United States Department of Neuroscience Johns Hopkins UniversityBaltimoreMD 21205United States

BACKGROUND Obesity is a disease state with serious adverse metabolic complications,including glucose intolerance and type 2 diabetes that currently has no *** and understanding roles of various modulators of body composition and glucose homeostasis is required for developing effective ***-1(Sdc1) is a member of the heparan sulfate proteoglycan family that has mainly been investigated for its role in regulating proliferation and survival of epithelia and tumor cells,but little is known about its roles in regulating obesity and glucose *** To examine the role of Sdc1 in regulating body fat and glucose *** We used female wild type and Sdc1 knockout(Sdc1 KO) mice on BALB/c background and multiple *** measurements(rates of oxygen consumption,carbon dioxide production,respiratory exchange ratio and energy expenditure) were performed using an open-flow indirect calorimeter with additional features to measure food intake and physical *** intolerance and insulin resistance were measured by established tolerance test *** Although our primary goal was to investigate the effects of Sdc1 deficiency on body fat and glucose homeostasis,we uncovered that Sdc1 regulates multiple metabolic ***1 KO mice have reduced body weight due to significant decreases in fat and lean masses under both chow and high fat diet *** reduced body weight was not due to changes in food intakes,but Sdc1 KO mice exhibited altered feeding behavior as they ate more during the dark phase and less during the light phase than wild type *** addition,Sdc1 KO mice suffered from high rate of energy expenditure,glucose intolerance and insulin *** These results reveal critical multisystem and opposing roles for Sdc1 in regulating normal energy balance and glucose *** results will have important implications for targeting Sdc1 to modulate metabolic ***,we offe

关键词： Syndecan-1 High fat diet Indirect calorimetry Energy expenditure IL-17 Feeding pattern

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Influence of Land Use Activities on Spatial and Temporal Variation of Nutrient Deposition in Mwanza Region: Implication to the Atmospheric Loading to the Lake Victoria

引用

Atmospheric and Climate Sciences 2013年第2期3卷 224-234页

作者： Said ali hamad Vuai John D. Ibembe Nancy W. Mungai Department of Chemistry College of Natural and Mathematical Sciences Department of Crop Science Egerton University Kenya Department of Humanities Busoga University Uganda

Increase in population growth and the associated activities have increased the nutrient input to the Lake Victoria through atmosphere and river discharge. Atmospheric input of nutrient is believed to exceed that of river discharge due to relatively higher contribution of water mass to the Lake from atmosphere. However, precipitation characteristics with respect to nutrients have not been well studied to allow qualification and quantification of atmospheric contribution to the Lake Victoria. This study was conducted to investigate influence of land use activities on spatial and temporal variation of nutrient inputs from atmosphere and to estimate atmospheric loading to the Lake Victoria. The results revealed that there is significant spatial and temporal variation of nutrient deposition in the study area. High concentrations of nutrients were observed during short rains starting from September to December. This was attributed to dissolution of nutrients from soil particals and ash residues due to biomass burning accumulated in the atmosphere during dry season of June to August. Spatial variation of nutrients reflects land use activities. Urban and peri-urban areas showed very high concentration of nitrate nitrogen due to industrial and vehicle emission while rural area showed high concentration of phosphorous species and reduced forms of nitrogen species reflecting agricultural activities and animal keeping. Generally, nutrient deposition load was higher in rural area compared to urban with respective values of 15.5 and 13.9 kg·haˉ1·yˉ1 for total nitrogen and 6.1 and 2.8 kg·haˉ1·yˉ1 for total phosphorous. These results suggest that in order to realize significant reduction of nutrient input to the Lake Victoria, measures should be taken to control agricultural activities through proper land use planning. The measure may be directed to reduce biomass burning, emission from industries and vehicle as well as animal residue.

关键词： Nutrient Landuse Lake Victoria Precipitation Atmospheric Pollution

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Temperature effect on the corrosion and passivation characterization of Ni_(82.3)Cr_7Fe_3Si_(4.5)B_(3.2) alloy in acidic media

引用

International Journal of Minerals,Metallurgy and Materials 2016年第2期23卷 205-214页

作者： Khadijah M.Emran Sanaa T.Arab Aisha M.Al-Turkustani hamad A.Al-Turaif Chemistry Department Faculty of Science Taibah University Department of Chemistry Faculty of Sciences Al-Faisaliah King Abdulaziz University Department of Chemical and Materials Engineering King Abdulaziz University

The effects of temperature on corrosion and the electrochemical behavior of Ni82.3Cr7Fe3Si4.5B3.2 glassy alloy in HC1,H2SO4,and H3PO4 acids were studied using AC and DC *** data reveal that the susceptibility to localized corrosion increases with increasing *** polarization curves reveal that the bulk glassy alloy is spontaneously passivated at all the investigated temperature in H2SO4 and H3PO4 solutions.A localized corrosion effect in HCl solution is clearly *** apparent activation energies in the regions of Tafel,active,and passive,as well as the enthalpies and entropies of the dissolution process were determined and *** high apparent activation energy（Ea） value for H3PO4 solution in Tafel region is explained by the low aggressivity of PO4^3- ions.

关键词： nickel alloys corrosion temperature effect acidic environment passivation polarization

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Preparation of quantum size of tin oxide: Structural and physical characterization

引用

Progress in Natural Science:Materials International 2016年第2期26卷 145-151页

作者： N.M.Shaalan D.hamad A.Y.Abdel-Latief M.A.Abdel-Rahim Physics Department Faculty of Science Assiut University

SnO2NPs were successfully prepared via a hydrothermal method. X-ray diffraction analysis con fi rmed the rutile tetragonal structure of SnO2NPs. The crystallite size increased from 1.18 to 5.06 nm with increasing the preparation temperature from 100 to 180 °C. The SEM photography of the products exhibited the agglomeration of the SnO2nanocrystals to large view particles, while TEM images con fi rmed the polycrystalline phase and crystallite size those analyzed from XRD. The UV–vis absorption of ethanol suspended SnO2NPs was measured. The optical band-gap energies（Eg） were signi fi cantly blue-shifted due to quantum con fi nement. Fluorescence spectra came to con fi rm this shift, where a clear shift in the maximum emission peak was observed. Stokes shift of SnO2nanocrystals was found to be crystallite size dependent.

关键词： Nanostructures Tin dioxide Luminescence Optical properties

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Fractional Order Modeling of Predicting COVID-19 with Isolation and Vaccination Strategies in Morocco

引用

Computer Modeling in Engineering & Sciences 2023年第8期136卷 1931-1950页

作者： Lakhlifa Sadek Otmane Sadek hamad Talibi Alaoui Mohammed S.Abdo Kamal Shah Thabet Abdeljawad Laboratory of Engineering Sciences for Energy National School of Applied SciencesChouaib Doukkali UniversityEl Jadida10002Morocco Department of Mathematics Faculty of SciencesChouaib Doukkali UniversityEl Jadida10002Morocco Department of Mathematics Hodeidah UniversityAl-Hudaydah91911Yemen Department of Mathematics and Sciences Prince Sultan UniversityRiyadh11586Saudi Arabia Department of Mathematics University of MalakandChakdara Dir(L)Khyber Pakhtankhawa18000Pakistan Department of Medical Research China Medical UniversityTaichung40402Taiwan

In this work,we present a model that uses the fractional order Caputo derivative for the novel Coronavirus disease 2019(COVID-19)with different hospitalization strategies for severe and mild cases and incorporate an awareness *** generalize the SEIR model of the spread of COVID-19 with a private focus on the transmissibility of people who are aware of the disease and follow preventative health measures and people who are ignorant of the disease and do not follow preventive health ***,individuals with severe,mild symptoms and asymptomatically infected are also *** basic reproduction number(R0)and local stability of the disease-free equilibrium(DFE)in terms of R0 are ***,the uniqueness and existence of the solution are *** simulations are performed by using some real values of ***,the immunization of a sample of aware susceptible individuals in the proposed model to forecast the effect of the vaccination is also ***,an investigation of the effect of public awareness on transmission dynamics is one of our aim in this ***,a prediction about the evolution of COVID-19 in 1000 days is *** the qualitative theory of the existence of a solution,we use some tools of nonlinear analysis,including Lipschitz ***,for the numerical interpretation,we use the Adams-Moulton-Bashforth *** the numerical results are presented graphically.

关键词： Fractional calculus caputo derivatives COVID-19 reproduction number future prediction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Calibration of CO and CO2 Monitors Used in Periodic Inspection of Vehicles at Fixed Stations for Environmental Control

引用

Green and Sustainable Chemistry（绿色与可持续化学） 2024年第2期 29页

作者： Adel Bassuoni Shehata Abdulrahman Rashed Al Askar Najjy hamad Al Yami Abdullah Suleiman Al Owaysi Sultan K.Alharbi

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

Neoadjuvant therapy for pancreatic ductal adenocarcinoma:Opportunities for personalized cancer care

引用

World Journal of Gastroenterology 2021年第27期27卷 4383-4394页

作者： Ahmad hamad Zachary J Brown Aslam M Ejaz Mary Dillhoff Jordan M Cloyd Department of Surgery The Ohio State University Wexner Medical CenterColumbusOH 43215United States

Pancreatic ductal adenocarcinoma(PDAC)is an aggressive malignancy that is best treated in a multidisciplinary fashion using surgery,chemotherapy,and *** chemotherapy has shown to have a significant survival benefit in patients with resected ***,up to 50%of patients fail to receive adjuvant chemotherapy due to postoperative complications,poor patient performance status or early disease *** order to ensure the delivery of chemotherapy,an alternative strategy is to administer systemic treatment prior to *** oncology refers to the application of diverse strategies to target therapies specific to characteristics of a patient’s *** traditionally emphasized in selecting targeted therapies based on molecular,genetic,and radiographic biomarkers for patients with metastatic disease,the neoadjuvant setting is a prime opportunity to utilize personalized *** this article,we describe the current evidence for the use of neoadjuvant therapy(NT)and highlight unique opportunities for personalized care in patients with PDAC undergoing NT.

关键词： Pancreatic cancer Preoperative therapy FOLFIRINOX Precision oncology Patient-reported outcomes Personalized medicine Targeted therapy Whipple Pancreatectomy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：