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First complete genomic sequence analysis of canine distemper virus in wild boar

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Virologica Sinica 2024年第4期39卷 702-704页

作者： Tong Wang haiying du Na Feng Yuhang Liu Yu Xu Heting Sun Peng Peng Siyuan Qin Xiaotian Zhang Yan Liu Mingyuan Yu Hongrui Liang Biao He Guoqiang Zhu Changchun Tu Zhongzhong Tu Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses Yangzhou UniversityYangzhou 225009China Changchun Veterinary Research Institute Chinese Academy of Agricultural SciencesChangchun 130122China Biological Disaster Control and Prevention Center National Forestry and Grassland AdministrationShenyang 110034China

Dear Editor,Canine distemper virus(CDV)is the causal agent of a highly contagious viral infectious disease that affects domestic and wild carnivores *** is an enveloped,non-segmented negative sense RNA virus that belongs to the Morbillivirus genus in Paramyxoviridae family,which contains viruses of epidemiological relevance to humans and *** on the variability of the hemagglutinin gene(H),CDV strains have been at least 21 major genetic lineages:America-1 to America-5,Canada-1 and-2,Asia-1 to Asia-6,Europe wild-life,Arctic,Africa-1/South Africa,Africa-2,South America-1 to South America-3 and Rockborn-like(Giacinti et al.,2022).Mutations in the binding sites of the H protein,which interact with viral entry receptors such as signaling lymphocytic activation molecule(SLAM)and nectin-4,are associated with the emergence of the disease in new host species(Beineke et al.,2015).

关键词： distemper Canada globally

基于递进式理论的多元化干预方案的构建及其对中耳炎患者康复效果的影响

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中国医药科学 2024年第7期14卷 123-126页

作者：杜海英广东省中山市中医院耳鼻喉科广东中山528400

目的探讨与分析基于递进式理论的多元化干预方案的构建及其对中耳炎患者康复效果的影响。方法前瞻性选择2020年3月至2022年3月在中山市中医院接受治疗的110例慢性化脓性中耳炎患者为研究对象,以随机数表法将其分为护理A组和护理B组,每组... 详细信息

目的探讨与分析基于递进式理论的多元化干预方案的构建及其对中耳炎患者康复效果的影响。方法前瞻性选择2020年3月至2022年3月在中山市中医院接受治疗的110例慢性化脓性中耳炎患者为研究对象,以随机数表法将其分为护理A组和护理B组,每组各55例。护理A组予以常规护理,护理B组则在A组基础上加以进行递进式理论的多元化干预。观察并分析两组纳入患者的听力疗效、生活质量评分、焦虑自评量表(SAS)与抑郁自评量表(SDS)评分、护理满意度、治疗时间与费用、并发症发生率。结果干预后护理B组患者的听力疗效、生活质量评分、护理满意度显著高于护理A组,差异有统计学意义(P<0.05)。干预后护理B组患者的听力改善时间、中耳炎积液消失时间、治疗费用、SAS与SDS评分、并发症总发生率明显低于护理A组,差异有统计学意义(P<0.05)。结论中耳炎患者采用基于递进式理论的多元化干预后的听力疗效显著,可有效提升患者的生活质量、护理满意度,减轻其抑郁与焦虑情况,减少治疗时间与费用,并发症发生率低,值得临床广泛使用。

关键词：递进式多元化护理干预中耳炎康复效果

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有形有感有效地将铸牢中华民族共同体意识融入高校法治观教育

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民族高等教育研究 2024年第4期12卷 20-25页

作者：杜海英程延军内蒙古大学马克思主义学院内蒙古呼和浩特010021 内蒙古大学法学院内蒙古呼和浩特010021

民族团结是我国各族人民的生命线,中华民族共同体意识是民族团结之本。大学生是社会主义事业的建设者和接班人,坚持以习近平法治思想为指引,有形有感有效地将铸牢中华民族共同体意识融入高校法治观教育,引导其自觉维护祖国统一、国家安... 详细信息

民族团结是我国各族人民的生命线,中华民族共同体意识是民族团结之本。大学生是社会主义事业的建设者和接班人,坚持以习近平法治思想为指引,有形有感有效地将铸牢中华民族共同体意识融入高校法治观教育,引导其自觉维护祖国统一、国家安全、社会稳定,依法处理民族事务意义重大。为此,各高校要培养一支谙熟民族法治教育的高素质师资队伍,制定实施将法治理念与民族团结进步教育有机结合的教学方案,进而建立协同育人的长效机制。

关键词：铸牢中华民族共同体意识高校法治观教育有形有感有效融入

养血滋阴方联合针刺治疗糖尿病眼底出血临床研究

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新中医 2024年第7期56卷 92-97页

作者：陈俊卿来坚张蕊杜海英杭州市中医院眼科浙江杭州310007

目的:观察养血滋阴方联合针刺治疗糖尿病眼底出血的临床疗效及对动脉血流、视野的影响。方法:采用随机数字表法将124例糖尿病眼底出血患者分为对照组、观察组各62例。2组均给予常规西药治疗,对照组在常规西药治疗基础上联用针刺治疗,观... 详细信息

目的:观察养血滋阴方联合针刺治疗糖尿病眼底出血的临床疗效及对动脉血流、视野的影响。方法:采用随机数字表法将124例糖尿病眼底出血患者分为对照组、观察组各62例。2组均给予常规西药治疗,对照组在常规西药治疗基础上联用针刺治疗,观察组在对照组基础上联用养血滋阴方治疗,2组连续治疗1个月。比较2组治疗前后眼动脉血流指标(舒张期血流速度峰值、收缩期血流速度峰值、阻力指数)、眼底出血面积、黄斑厚度、视野灰度值、血管瘤体积、视网膜电图振荡电位(OPs);比较2组治疗前后最佳矫正视力(BCVA)、视功能相关的生活质量量表(VFQ-25)、中医证候评分;比较2组治疗前后趋化因子样受体1(CMKLR1)、肿瘤坏死因子-α(TNF-α)、血管内皮生长因子(VEGF)、血小板源性生长因子-BB(PDGF-BB)水平,并评估2组临床疗效及不良反应发生情况。结果:观察组总有效率96.77%,高于对照组83.87%(P<0.05)。2组治疗后CMKLR1、TNF-α、VEGF、PDGF-BB水平及眼底出血面积、黄斑厚度、视野灰度值、血管瘤体积、阻力指数、OPs、VFQ-25、中医证候评分均较治疗前降低(P<0.05),观察组治疗后CMKLR1、TNF-α、VEGF、PDGF-BB水平及眼底出血面积、黄斑厚度、视野灰度值、血管瘤体积、阻力指数、OPs、VFQ-25、中医证候评分均低于对照组(P<0.05)。2组治疗后舒张期血流速度峰值、收缩期血流速度峰值、BCVA水平升高(P<0.05),观察组治疗后舒张期血流速度峰值、收缩期血流速度峰值、BCVA水平高于对照组(P<0.05)。结论:养血滋阴方联合针刺治疗糖尿病眼底出血疗效确切,能够抑制机体炎症,保护患者视网膜屏障,改善眼动脉血流、视力,提高生活质量。

关键词：糖尿病眼底出血养血滋阴方针刺炎症视网膜屏障眼动脉血流视网膜电图振荡电位

过渡金属硫化物WS_(2)气敏性能及敏感机理研究

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大连民族大学学报 2024年第1期26卷 36-42页

作者：丛丽颖李清宇杜海英王敬张钊睿大连民族大学机电工程学院辽宁大连116650 大连理工大学机械工程学院辽宁大连116024

采用焙烧分解法合成了过渡金属硫化物WS_(2),对其形貌、结构和成分进行了表征分析,制备了WS_(2)气体传感器,研究了其对环境污染气体NO_(2)及多种干扰气体的气敏性能。实验结果显示,相较于其他干扰气体,WS_(2)气体传感器对NO_(2)的响应... 详细信息

采用焙烧分解法合成了过渡金属硫化物WS_(2),对其形貌、结构和成分进行了表征分析,制备了WS_(2)气体传感器,研究了其对环境污染气体NO_(2)及多种干扰气体的气敏性能。实验结果显示,相较于其他干扰气体,WS_(2)气体传感器对NO_(2)的响应灵敏度最高,具有良好的长期稳定性和气体选择性。基于密度泛函理论计算了WS_(2)分子对NO_(2)及其干扰气体的吸附能、电荷差分、态密度等微观电子特性,分析了过渡金属硫化物WS_(2)对NO_(2)的吸附机理。基于密度泛函理论的机理分析与实验结果相一致。

关键词：过渡金属硫化物气敏性能密度泛函理论敏感机理

Epizootiological surveillance of porcine circoviruses in free-ranging wild boars in China

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Virologica Sinica 2023年第5期38卷 663-670页

作者： Wenjie Gong haiying du Tong Wang Heting Sun Peng Peng Siyuan Qin Haidong Geng Zheng Zeng Wangwang Liang Hongquan Ling Changchun Tu Zhongzhong Tu State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Key Laboratory for Zoonosis Research of the Ministry of EducationInstitute of Zoonosisand College of Veterinary MedicineJilin UniversityChangchun130062China Changchun Veterinary Research Institute Chinese Academy of Agricultural SciencesChangchun130122China Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses Yangzhou UniversityYangzhou225009China Biological Disaster Control and Prevention Center National Forestry and Grassland AdministrationShenyang110034China Chongqing Animal Disease Prevention and Control Center Chongqing401120China

Four species of porcine circoviruses(PCV1–4)have been reported to circulate in Chinese domestic pigs,while the epizootiology of these viruses in free-ranging wild boars in China remains *** this study,tissue and serum samples collected from diseased or apparently healthy wild boars between 2018 and 2020 in 19 regions of China were tested for the prevalence of PCV1–4 *** rates of PCV1,PCV2,and PCV3 DNA in the tissue samples of Chinese wild boars were 1.6%(4/247),58.3%(144/247),and 10.9%(27/247)respectively,with none positive for *** analysis of viral genome showed that the four PCV1 strains distributed in Hunan and Inner Mongolia shared 97.5%–99.6%sequence identity with global distributed reference *** of the ORF2 gene sequences showed that 80 PCV2 strains widely distributed in 18 regions shared 79.5%–100%sequence identity with reference strains from domestic pigs and wild boars,and were grouped into PCV2a(7),PCV2b(31)and PCV2d(42).For PCV3,17 sequenced strains shared 97.2%–100%nucleotide identity at the genomic level and could be divided into PCV3a(3),PCV3b(2)and PCV3c(12)based on the phylogeny of ORF2 gene *** data revealed antibody positive rates against PCV1 and PCV2 of 11.4%(19/167)and 53.9%(90/167)*** data obtained in this study improved our understanding about the epidemiological situations of PCVs infection in free-ranging wild boars in China and will be valuable for the prevention and control of diseases caused by PCVs infection.

关键词： Porcine circoviruses(PCVs) Epizootiology Wild boar China

Along-track Calibration of the Zhurong Rover Magnetometer

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Science China Earth Sciences 2024年第2期67卷 552-565页

作者： Hao LUO Aimin du Yasong GE Ying ZHANG haiying LI Lin TIAN Kuixiang ZHANG Shuquan SUN Lin ZHAO Zhi LI Xiao FENG CAS Engineering Laboratory for Deep Resources Equipment and Technology Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100029China College of Earth Science University of Chinese Academy of SciencesBeijing100049China National Astronomical Observatories Chinese Academy of SciencesBeijing100101China

As part of the Chinese Tianwen-1 mission,the Zhurong Rover began its scientific investigation in the southern Utopia Planitia after its successful landing in 15 May,*** Zhurong Rover magnetometer(RoMAG),one of the six payloads onboard the rover,includes two identical high-sensitivity triaxial fluxgate magnetometers and can implement mobile magnetic measurements on the surface of *** a rover magnetic compensation procedure was conducted to remove the magnetic interferences pre-launch,due to the different state of the payloads and electric power system such as the solar panel,an along-track calibration of the magnetometer is necessary to obtain a more accurate Martian magnetic *** methods,mast yaw rotations and Rover yaw rotations were utilized separately to determine the Martian horizontal magnetic *** show that the Martian horizontal magnetic components determined by the two methods are in good agreement,with the root mean square deviation less than 2.0 *** vertical component was also constrained through the pitch movements of the mast by assuming the interferences field distributes like a dipole field.A linear correlation between magnetic field measurements and the solar array currents was derived to calibrate the body field during the regular *** conclude that more accurate measurements could be made when applying the calibration results in the magnetic survey on the surface of Mars.

关键词： The Zhurong Rover Magnetometer Along-track calibration Remnant magnetization

Progress and prospects of EOR technology in deep,massive sandstone reservoirs with a strong bottom-water drive

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Energy Geoscience 2024年第1期5卷 249-255页

作者： haiying Liao Ting Xu Hongmin Yu SINOPEC Exploration&Production Research Institute Beijing100083China

The Triassic massive sandstone reservoir in the Tahe oilfield has a strong bottom-water drive and is characterized by great burial depth,high temperature and salinity,a thin pay zone,and strong *** present,the water-cut is high in each block within the reservoir;some wells are at an ultrahigh water-cut stage.A lack of effective measures to control water-cut rise and stabilize oil production have necessitated the application of enhanced oil recovery(EOR)*** paper investigates the development and technological advances for oil reservoirs with strong edge/bottom-water drive globally,and compares their application to reservoirs with characteristics similar to the Tahe *** the technological advances,gas injection from the top and along the direction of structural dip has been used to optimize the flow field in a typical bottom-water drive ***-water coning is restrained by gas injection-assisted water *** addition,increasing the lateral driving pressure differential improves the plane sweep efficiency which enhances oil recovery in *** injection technology in combination with technological measures like channeling prevention and blocking,and water plugging and profile control,can achieve better results in reservoir *** flooding tests in the Tahe oilfield are of great significance to identifying which EOR technology is the most effective and has the potential of large-scale application for improving development of deep reservoirs with a strong bottomwater drive.

关键词： Edge water Bottom water Water coning Massive reservoir Water injection Gas injection

Trackingδ13C andδ18O fluctuations uncovers stable modes and key patterns of paleoclimate

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Geoscience Frontiers 2024年第4期15卷 115-133页

作者： Shifeng Sun haiying Wang Yongjian Huang School of Science China University of Geosciences(Beijing)Beijing 100083China State Key Laboratory of Biogeology and Environmental Geology China University of Geosciences(Beijing)Beijing 100083China School of Earth Sciences and Resources China University of Geosciences(Beijing)Beijing 100083China

The examination of fluctuations in the correlations betweenδ13C andδ18O is of significant importance for the reconstruction of the Earth's climate history.A key challenge in paleoclimatology is finding a suitable method to represent the correlated fluctuation system betweenδ13C andδ*** method must be able to handle data sets with missing or inaccurate values,while still retaining the full range of dynamic information about the *** non-linear and complex correlations betweenδ13C andδ18O poses a chal-lenge in developing reliable and interpretable *** transition network,which involves embedding theδ13C andδ18O sequence into the network using phase space reconstruction,is a coarse-grained based *** approach is well-suited to nonlinear,complex dynamic systems,and is particularly adept at emerging knowledge from low-quality *** have effectively represented the fluctuations in the correlation betweenδ13C andδ18O since 66 million years ago(Ma)using a system of complex *** system,which has topological dynamical structures,is able to uncover the stable modes and key patterns in Cenozoic climate *** findings could help to improve climate models and predictions of future climate change.

关键词： Cenozoic climate dynamics Correlation analysis Complex network Coarse-grained methods Phase space reconstruction