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考虑电纳作用的输电可变成本计算

电力系统自动化 2025年第1期49卷 193-199页

作者：鲍海宋唯溢华北电力大学电气与电子工程学院北京市102206

科学准确地计算输电可变成本对于电力市场公平竞争具有重要意义。通过潮流追踪发现电源向电纳元件传输功率的过程也会产生有功损耗,进而影响最终的输电可变成本。因此,计算输电可变成本时需要考虑电纳元件的物理、经济特性。文中首先对... 详细信息

科学准确地计算输电可变成本对于电力市场公平竞争具有重要意义。通过潮流追踪发现电源向电纳元件传输功率的过程也会产生有功损耗,进而影响最终的输电可变成本。因此,计算输电可变成本时需要考虑电纳元件的物理、经济特性。文中首先对有功负荷及电纳等无功负荷建立满足自身功率平衡的模型;然后,借助费用守恒原则得到符合经济特性的费用计算模型。采用所提出的模型计算得到的输电可变成本能够提供丰富和准确的经济信息。最后,通过算例分析验证了所提计算模型与计算结果的合理性与准确性。

关键词：输电可变成本电纳潮流费用守恒无功输电费用电力市场

NIR-Ⅱfluorescence lateral flow immunosensor based on efficient energy transfer probe for point-of-care testing of tumor biomarkers

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Chinese Chemical Letters 2025年第1期36卷 469-473页

作者： Zhaorui song Qiulian Hao Bing Li Yuwei Yuan Shanshan Zhang Yongkuan Suo hai-Hao Han Zhen Cheng Shandong Laboratory of Yantai Drug Discovery Bohai Rim Advanced Research Institute for Drug DiscoveryYantai 264117China State Key Laboratory of Drug Research Molecular Imaging CenterShanghai Institute of Materia MedicaShanghai 201203China Institute of Molecular Medicine Joint Laboratory for Molecular Medicine Northeastern University Shenyang 110000China Pharmacy College Shandong First Medical University&Shandong Academy of Medical SciencesJi’nan 250117China University of Chinese Academy of Sciences Beijing 100049China

Fluorescence lateral flow immunoassay(LFA)has emerged as a powerful tool for rapid screening of various biomarkers owing to its simplicity,sensitivity and *** is noteworthy that fluorescent probe mainly determines the analytical performance of *** to the emission and excitation wavelengths are located in the visible region,most fluorophores are inevitably subject to light scattering and background ***,we reported a novel LFA sensor based on the second near-infrared(NIR-Ⅱ)fluorescent probe with excellent anti-interference *** designed NIR-Ⅱprobe was the Nd^(3+)and Yb^(3+)doped rare earth nanoparticles(RENPs)by employing Nd^(3+)as energy donor and Yb^(3+)as energy acceptor,which of the donor-acceptor energy transfer(ET)efficiency reached up to 80.7%.Meanwhile,relying on the convenient and effective encapsulation strategy of poly(lactic-co-glycolic acid)(PLGA)microspheres to RENPs,the surface functionalized NIR-Ⅱprobe(RE@PLGA)was obtained for subsequent *** from the optical advantages of NIR-Ⅱprobe,this proposed NIR-ⅡLFA displayed a good linear relationship ranging from 7 ng/mL to 200 ng/mL for the detection ofα-fetoprotein(AFP),an important biomarker of hepatocellular carcinoma(HCC).The limit of detection(LOD)was determined as low as 3.0 ng/m L,which was of 8.3 times lower than clinical cutoff *** is promising that LFA sensor based on this efficient RENPs probe provides new opportunities for high sensitive detection of various biomarkers in biological samples.

关键词： Donor-acceptor energy transfer(ET) Lateral flow immunoassay(LFA) The second near-infrared(NIR-Ⅱ) fluorescence Rare-earth nanoparticles(RENPs) Poly(lactic acid-co-glycolic acid)(PLGA) Tumor biomarker

3D bioprinted advanced cartilage organoids with engineered magnetic nanoparticles polarized-BMSCs/alginate/gelatin for cartilage tissue regeneration

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Nano Research 2025年第2期18卷 541-556页

作者： Zhiyu Ding Junjie Huang Yijun Ren Ning Tang Xin Luo Huancheng Zhu Xu Cao ming Zhao song Wu Department of Orthopedics Third Xiangya Hospital of Central South UniversityChangsha 410013China Lab of Research and Engineering of Cell Therapy Technology Hangzhou Institute of Medicine Chinese Academy of SciencesHangzhou 310018China Department of Neurology Xiangya Hospital of Central South UniversityChangsha 410028China

Cartilage defects are commonly observed in orthopedic clinical *** to the unique structure of cartilage tissue,current clinical treatments cannot fully address this *** organoids are three-dimensional(3D)active tissue structures constructed in vitro to mimic the structure and function of natural cartilage tissue and can be utilized for disease research and cartilage *** this study,we engineered MNPs-BMSCs by introducing magnetic nanoparticles(MNPs)into bone marrow mesenchymal stem cells(BMSCs).Under the influence of the magnetic field induced by the MNPs,MNPs-BMSCs became polarized,significantly enhancingtheir aggregation,migration,andchondrogenic differentiation *** then used these engineered MNPs-BMSCs as seed cells and applied 3D bioprinting technology to construct an advanced cartilage organoid using a MNPs-BMSC/alginate/gelatin *** structure partially mimics the middle layer of a *** advanced cartilage organoid demonstrated superior chondrogenic differentiation ability and mechanical properties in *** significantly enhanced tissue repair in cartilage defect areas in vivo,restoring the normal structure of the cartilage ***,the engineered MNPs-BMSCs/alginate/gelatin advanced cartilage organoids offer a promising approach for studying cartilage tissue in vitro and advancing cartilage repair within the field of tissue engineering.

关键词： magnetic nanoparticles cell polarization three-dimensional(3D)bioprinting cartilage organoid cartilage repair

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网络安全用户行为画像方案设计

通信技术 2017年第4期50卷 789-794页

作者：何雪海黄明浩宋飞卫士通信息产业股份有限公司四川成都610041

用户行为分析是近年来网络安全领域研究的热点之一,但是一直受限于相关数据存储和分析的能力而用处不大。对历史行为数据建模,是这类安全分析应用的关键。计算机用户相关的行为数据对于预测用户行为、异常检测非常有用。因此,提出一种... 详细信息

用户行为分析是近年来网络安全领域研究的热点之一,但是一直受限于相关数据存储和分析的能力而用处不大。对历史行为数据建模,是这类安全分析应用的关键。计算机用户相关的行为数据对于预测用户行为、异常检测非常有用。因此,提出一种大数据网络安全用户行为画像设计方案。该方案结合用户角色和个人用户操作行为特征,利用用户日志历史信息勾勒出用户行为画像,并给出用户行为安全画像实例。该方案能有效利用用户历史行为数据,使得安全管理系统能准实时地判断用户行为异常,提高网络安全类产品的实时响应能力。实践表明,该方案能应用于异常检测、日志审计、网络安全评估等。

关键词：用户画像用户行为分析综合监督管理系统大数据日志分析

MoS_(2)Lubricate‑Toughened MXene/ANF Composites for Multifunctional Electromagnetic Interference Shielding

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Nano-Micro Letters 2025年第2期17卷 358-371页

作者： Jiaen Wang Wei ming Longfu Chen Tianliang song Moxi Yele Hao Zhang Long Yang Gegen Sarula Benliang Liang Luting Yan Guangsheng Wang School of Physical Science and Engineering Beijing Jiaotong UniversityBeijing 100044People’s Republic of China Key Laboratory of Bio‑Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191People’s Republic of China

The design and fabrication of high toughness electromagnetic interference(EMI)shielding composite films with diminished reflection are an imperative task to solve electromagnetic pollution *** MXene/ANF(aramid nanofibers)–MoS_(2)composite films with nacre-like layered structure here are fabricated after the introduction of MoS_(2)into binary MXene/ANF composite *** introduction of MoS_(2)fulfills an impressive“kill three birds with one stone”improvement effect:lubrication toughening mechanical performance,reduction in secondary reflection pollution of electromagnetic wave,and improvement in the performance of photothermal *** the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 50:50),the strain to failure and tensile strength increase from 22.1±1.7%and 105.7±6.4 MPa and to 25.8±0.7%and 167.3±9.1 MPa,*** toughness elevates from 13.0±4.1 to 26.3±0.8 MJ m^(−3)(~102.3%)*** the reflection shielding effectiveness(SE_(R))of MXene/ANF(mass ratio of 50:50)decreases~10.8%.EMI shielding effectiveness(EMI SE)elevates to 41.0 dB(8.2–12.4 GHz);After the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 60:40),the strain to failure increases from 18.3±1.9%to 28.1±0.7%(~53.5%),the SE_(R)decreases~22.2%,and the corresponding EMI SE is 43.9 *** MoS_(2)also leads to a more efficient photothermal conversion performance(~45 to~55℃).Additionally,MXene/ANF–MoS_(2)composite films exhibit excellent electric heating performance,quick temperature elevation(15 s),excellent cycle stability(2,2.5,and 3 V),and long-term stability(2520 s).Combining with excellent mechanical performance with high MXene content,electric heating performance,and photothermal conversion performance,EMI shielding ternary MXene/ANF–MoS_(2)composite films could be applied in many industrial *** work broadens how to achieve a balance between mechanical properties and versatility of composites in the case of high-function fillers.

关键词： MXene-MoS_(2) Lubrication toughening EMI shielding Photothermal conversion Electric heating performance

Temperature Control of Bench-Scaled Batch Reactor Equipped with a Monofluid Heating/Cooling System

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Journal of Thermal Science 2014年第2期23卷 187-195页

作者： TENG hai-peng song Yi-ming School of Chemical Engineering Northwest University

An advanced control concept, Predictive Functional Control （PFC）, is applied for temperature control of a bench-scaled batch reactor equipped with monofluid heating/cooling system. First principles process models are developed. Based on achieved models, significant process variables, which are difficult or impossible to measure online, are estimated from easily measured variables, and cascade PFC control strategy has been projected and implemented in Matlab RI 4. The dynamics of individual subunits is explicitly taken into consideration by internal model in the control algorithms, and model uncertainty, various process disturbances are compensated by modifi- cation of internal model. The experimental results present an excellent capability of tracking the set point, and the success of PFC technique as a process control paradigm is illustratively demonstrated.

关键词： temperature control batch reactor mono-fluid heating/cooling system

Low-dose exposure to microplastics retards meiotic maturation via HDAC3 insufficiency

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Science China Life Sciences 2025年

作者： Qi Zhao ming Zong Entong song Hongye Linghu Xuanwen Li Baicui Wang songling Xiao Wanchun Guan Jianzhong Su Jiaming Zhang Jingzhang Ji Qingran Kong Zhejiang Provincial Key Laboratory of Medical Genetics Key Laboratory of Laboratory Medicine Ministry of Education School of Laboratory Medicine and Life Sciences Wenzhou Medical University Oujiang Laboratory Zhejiang Lab for Regenerative Medicine Vision and Brain Health

Microplastics(MPs) are considered one of the main causes of male and female infertility. However, the reproductive toxicity and its related mechanisms are currently understood primarily through animal models with acute exposure to MPs. In this study, we demonstrate that lowdose exposure to polystyrene microplastics(PSMPs) leads to severely abnormal reproduction in females, manifested by oocyte meiotic maturation defect. Mechanistically, PSMPs exposure induce the overactivation of cell metabolism pathways, insufficient HDACs, and H4K16hyperacetylation in oocytes both in vivo and in vitro. When an HDAC3 inhibitor is added, the oocyte maturation defect, overactivation of cell metabolism pathways, and H4K16 hyperacetylation are recapitulated. Conversely, the overexpression of HDAC3 can rescue the defects in meiotic maturation induced by PSMPs. Our observations suggest a direct link between the maturation defects caused by PSMPs and HDAC3insufficiency. Thus, we propose potential treatments to address the meiotic maturation defect of oocytes in women highly exposed to MPs by activating or supplying HDAC3.

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Molecular mechanism of pancreatic ductal adenocarcinoma:The heterogeneity of cancer-associated fibroblasts and key signaling pathways

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World Journal of Clinical Oncology 2025年第2期16卷 18-28页

作者： Zhong-Yuan Hu Ding Ding Yu song Ya-Feng Deng Cheng-ming Zhang Tao Yu First School of Clinical Medicine Shaanxi University of Chinese MedicineXianyang 712000Shaanxi ProvinceChina College of Acupuncture and Massage Shaanxi University of Chinese MedicineXianyang 712000Shaanxi ProvinceChina Graduate School Guangzhou University of Chinese MedicineGuangzhou 510000Guangdong ProvinceChina Digestive Department I Shaanxi Provincial Hospital of Traditional Chinese MedicineXi’an 710000Shaanxi ProvinceChina

Pancreatic ductal adenocarcinoma stands out as an exceptionally fatal cancer owing to the complexities associated with its treatment and diagnosis,leading to a notably low five-year survival *** study offers a detailed exploration of epidemiological trends in pancreatic cancer and key molecular drivers,such as mutations in CDKN2A,KRAS,SMAD4,and TP53,along with the influence of cancer-associated fibroblasts(CAFs)on disease *** particular,we focused on the pivotal roles of signaling pathways such as the transforming growth factor-βand Wnt/β-catenin pathways in the development of pancreatic cancer and investigated their application in emerging therapeutic *** study provides new scientific perspectives on pancreatic cancer treatment,especially in the development of precision medicine and targeted therapeutic strategies,and demonstrates the importance of signaling pathway research in the development of effective therapeutic *** studies should explore the subtypes of CAFs and their specific roles in the tumor microenvironment to devise more effective therapeutic methods.

关键词： Pancreatic cancer Fibroblasts Signaling pathways Tumor microenvironment

青藏高原高寒草甸不同退化阶段植物氮利用速率变化

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草业学报 2025年第2期34卷 16-26页

作者：霍佳娟宋明华中国科学院地理科学与资源研究所生态系统网络观测与模拟重点实验室北京100101 中国科学院大学北京100049

氮(N)是植物生长繁殖的必需元素,以多种形式存在于生态系统中。高寒草甸位置特殊,气候严酷,土壤有效氮匮乏。过度放牧引起草甸发生退化演替,土壤速效养分流失严重,导致植物的氮素利用模式发生改变。以青海省黄南州泽库县高寒草甸为研究... 详细信息

氮(N)是植物生长繁殖的必需元素,以多种形式存在于生态系统中。高寒草甸位置特殊,气候严酷,土壤有效氮匮乏。过度放牧引起草甸发生退化演替,土壤速效养分流失严重,导致植物的氮素利用模式发生改变。以青海省黄南州泽库县高寒草甸为研究对象,选取轻度、中度、重度退化、侵蚀、严重侵蚀以及黑土滩6个退化阶段,利用稳定性同位素15N示踪的方法量化小嵩草对铵态氮(NH_(4)^(+)-N)和硝态氮(NO_(3)^(-)-N)吸收速率沿不同退化阶段的变化,以及草甸退化后期多度较高物种:小嵩草、橐吾、香薷对无机氮利用的差异。结果表明:沿退化序列,小嵩草对总无机氮的吸收速率呈波动下降趋势,其中对NH_(4)^(+)-N的吸收速率同总无机氮的吸收速率变化趋势一致,对NO_(3)^(-)-N的吸收速率呈波动上升趋势。除侵蚀和黑土滩阶段外,小嵩草对NH_(4)^(+)-N的吸收速率均为地下器官显著高于地上器官;除重度退化和黑土滩阶段外,其他阶段小嵩草对NO_(3)^(-)-N的吸收速率均为地下器官显著高于地上器官。退化后期,小嵩草在嵩草占优势斑块和杂草占优势斑块中对NO_(3)^(-)-N吸收方式无显著差异,而其在杂草占优势的斑块中对NH_(4)^(+)-N的吸收速率显著高于嵩草占优势的斑块。杂草斑块中的优势植物橐吾和香薷对NH_(4)^(+)-N和NO_(3)^(-)-N吸收方式差异显著,橐吾对NH_(4)^(+)-N的吸收速率显著高于NO_(3)^(-)-N,而香薷对二者的吸收速率无显著差异。综上,在高寒草甸不同退化阶段,植物物种采用不同的无机氮获取策略适应土壤养分状况,维持自身生存。深入认识草地不同退化阶段植物对土壤无机氮素的吸收利用能够深入理解物种共存机制,进而指导退化草地的合理恢复。

关键词：高寒草甸退化序列无机氮的不同化学形态氮吸收速率 15N示踪技术