检索结果-南通市图书馆

Chinese Chemical Letters 2010年第12期21卷 1482-1486页

作者： hai yan fu hai long wu jin fang nie yong jie yu hong yan zou ru qin yu State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical Engineering Hunan University Changsha 410082 China

A rapid,green and highly sensitive excitation-emission matrix（EEM） fluorescence method was proposed for analysis of irinotecan（CPT-11） in biological fluids including human plasma and urine samples of uncalibrated interferences with the aid of second-order *** to the serious spectral overlapping from biological matrices,the parallel factor analysis（PARAFAC） and the alternating normalization-weighted error（ANWE） have been recommended to perform directly calibration and overcome the problem which makes the traditional fluorospectrophotometer in *** results can be ***, performance of the proposed method was evaluated based on figures of merit and some statistical *** accuracy of both algorithms was validated by the elliptical joint confidence region（EJCR） *** precision and repeatability were also investigated by the relative standard deviations（RSDs） of intra-day and inter-day.

关键词： Irinotecan Biological fluids Excitation-emission matrix fluorescence PARAFAC ANWE

Searching for^(76)Ge neutrinoless double beta decay with the CDEX-1B experiment

在线全文

学校读者我要写书评

暂无评论

Chinese Physics C 2024年第10期48卷 11-22页

作者： Bing-Tao Zhang Jun-Zheng Wang Li-Tao yang Qian yue Ke-Jun Kang yuan-jing Li hai-Peng An C.Greeshma Jian-Ping Chang yun-Huan Chen Jian-Ping Cheng Wen-Han Dai Zhi Deng Chang-Hao fang Xin-Ping Geng Hui Gong Qiu-Ju Guo Xu-yuan Guo Li He Sheng-Ming He jin-Wei Hu Han-Xiong Huang Tu-Chen Huang hai-Tao Jia Xi Jiang S.Karmakar Hao-Bin Li Jian-Min Li jin Li Qian-yun Li Ren-Ming-jie Li Xue-Qian Li yu-Lan Li Yi-Fan Liang Bin Liao Fong-Kay Lin Shin-Ted Lin Jia-Xuan Liu Shu-Kui Liu yan-Dong Liu yu Liu yuan-yuan Liu Zhong-Zhi Liu Hao Ma yu-Cai Mao Qi-yuan nie jin-Hua Ning Hui Pan Ning-Chun Qi jie Ren Xi-Chao ruan Ze She Manoj Kumar Singh Tian-Xi Sun Chang-Jian Tang Wei-You Tang yang Tian Guang-fu Wang Li Wang qing Wang yu-Feng Wang yun-Xiang Wang Henry-Tsz-King Wong Shi-yong wu yu-Cheng wu Hao-yang Xing rui Xu Yin Xu Tao Xue yu-Lu yan Nan Yi Chun-Xu yu hai-Jun yu Jian-Feng yue Ming Zeng Zhi Zeng Feng-Shou Zhang Lei Zhang Zhen-Hua Zhang Zhen-yu Zhang Kang-Kang Zhao Ming-Gang Zhao Ji-fang Zhou Zu-Ying Zhou jing-Jun Zhou Key Laboratory of Particle and Radiation Imaging(Ministry of Education)and Department of Engineering Physics Tsinghua UniversityBeijing 100084 Department of Physics Tsinghua UniversityBeijing 100084 Institute of Physics Academia SinicaTaipei 11529 NUCTECH Company Beijing 100084 Yalong River Hydropower Development Company Chengdu 610051 College of Nuclear Science and Technology Beijing Normal UniversityBeijing 100875 College of Physics Sichuan UniversityChengdu 610065 School of Physics Peking UniversityBeijing 100871 Department of Nuclear Physics China Institute of Atomic EnergyBeijing 102413 Sino-French Institute of Nuclear and Technology Sun Yat-sen UniversityZhuhai 519082 School of Physics Nankai UniversityTianjin 300071 Department of Physics Banaras Hindu UniversityVaranasi 221005 Department of Physics Beijing Normal UniversityBeijing 100875

We operated a p-type point contact high purity germanium(PPCGe)detector(CDEX-1B,1.008 kg)in the China jinping Underground Laboratory(CJPL)for 500.3 days to search for neutrinoless double beta(0νββ)decay of^(76)Ge.A total of 504.3 kg⋅day effective exposure data was *** anti-coincidence and the multi/single-site event(MSE/SSE)discrimination methods were used to suppress the background in the energy region of interest(ROI,1989–2089 keV for this work)with a factor of 23.A background level of 0.33 counts/(keV⋅kg⋅yr)was *** lower limit on the half life of^(76)Ge 0νββdecay was constrained as T_(1/2)^(0ν)>1.0×10^(23)yr(90%C.L.),corresponding to the upper limits on the effective Majorana neutrino mass:<3.2–7.5 eV.

关键词： neutrinoless double beta decay CDEX point-contact germanium detector ^(76)Ge

CEPC Technical Design Report

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai wujun Cai Yijian Cai Yizhou Cai yuchen Cai haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che yuzhi Che Bin Chen Danping Chen fuqing Chen fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen jinhui Chen Ji-yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP jinR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection:a randomized trial

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2021年第10期6卷 3009-3018页

作者： Jun Liu Dan-Dan Li Wei Dong yu-Qi Liu yang wu Da-Xuan Tang fu-Chun Zhang Meng Qiu Qi Hua jing-yu He Jun Li Bai Du Ting-hai Du Lin-Lin Niu Xue-Jun Jiang Bo Cui Jiang-Bin Chen yang-Gan Wang hai-Rong Wang qin yu jing He Yi-Lin Mao Xiao-fang Bin yue Deng yu-Dan Tian qing-Hua Han Da-jin Liu Li-qin Duan Ming-Jun Zhao Cui-Ying Zhang hai-Ying Dai Ze-Hua Li Ying Xiao You-Zhi Hu Xiao-yu Huang Kun Xing Xin Jiang Chao-Feng Liu jing An Feng-Chun Li Tao Tao jin-Fa Jiang Ying yang Yao-Rong Dong Lei Zhang Guang fu Ying Li Shu-Wei Huang Li-Ping Dou Lan-Jun Sun Ying-Qiang Zhao jie Li yun Xia Jun Liu Fan Liu Wen-jin He Ying Li Jian-Cong Tan yang Lin Ya-Bin Zhou Jian-Fei yang Guo-qing Ma Hui-Jun Chen He-Ping Liu Zong-wu Liu Jian-Xiong Liu Xiao-Jia Luo Xiao-hong Bin Ya-Nan yu hai-Xia Dang Bing Li Fei Teng Wang-Min Qiao Xiao-long Zhu Bing-Wei Chen Qi-Guang Chen Chun-Ti Shen yong-yan Wang yun-Dai Chen Zhong Wang Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijingChina Department of Cardiology Chinese PLA General HospitalBeijingChina Department of Cardiology Dongfang Hospital Affiliated to Beijing University of Chinese MedicineBeijingChina Department of Geratology Peking University Third HospitalBeijingChina Department of Cardiology Xuan Wu HospitalCapital Medical UniversityBeijingChina Department of Cardiology Guang'anmen HospitalChina Academy of Chinese Medical SciencesBeijingChina Department of Cardiology First Affiliated Hospital of Henan University of Chinese MedicineZhengzhouHenanChina Department of Cardiology Wuhan University Renmin HospitalWuhanHubeiChina Department of Cardiology Wuhan University Zhongnan HospitalWuhanHubeiChina Affiliated Zhongshan Hospital of Dalian University DalianLiaoningChina Department of Cardiology Second Affiliated Hospital to Hunan University of Chinese MedicineChangshaHunanChina Department of Cardiology First Affiliated Hospital to Changchun University of Chinese MedicineChangchunJilinChina Department of Cardiology First Affiliated Hospital to Shanxi Medical UniversityTaiyuanShanxiChina Department of Cardiology Affiliated Hospital of Shanxi University of Chinese MedicineXianyangShanxiChina Department of Cardiology Changsha Central HospitalChangshaHunanChina Department of Cardiology Hubei Provincial Hospital of Traditional Chinese MedicineWuhanHubeiChina Department of Cardiology Shanxi Provincial People's HospitalXi'anShanxiChina Department of Cardiology Shanxi Province Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Xi'an City Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Shanghai Tongji HospitalShanghaiChina Department of Cardiology Shanghai Municipal Hospital of Traditional Chinese MedicineShanghaiChina Department of Cardiology The First Hospital of ChangshaChangshaHunanChina Department of Cardiology Xinhua Hospi

It's a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in thedfferentiated populations with complex diseases,as stable coronary heart ***,in an adaptive,31-center,randomized,double-blind trial invoving 920 patients with moderate symptomatic stable angina treated by 14-day Danhong injection(DHI),a kind of polyphamacological drug with high quality control,or placebo(0.9%saline),with 76-day following-up,we firstly confrmed that DHl couldincrease the proportion of patients with clinically significant changes on angina-frequency assessed by Seattle Angina Questionnaire(ASAQ-AF220)(12.78%at Day 30,95%confidence interval[C]5.86-19.71%,P=0.0003,13.82%at Day 6C0,95%CI 6.82-20.82%,P=0.0001and 8.95%at Day 90,95%CI 2.06-15.85%,P=0.01).We also found that there were no significant differences in new-onset major vascularevents(P=0.8502)and serious adverse events(P=0.9105)between DHl and *** performing the RNA sequencing in 62 selectedpatients,we developed a systemic modular approach tp identfy differentilly expressed modules(DEMs)of DHI with the Z_(summay)valueless than 0 compared with the control group,calculated by weighted gene co-expression network analysis(WGCNA),and sketched out thebasic framework on a modular map with 25 functional modules targeted by ***,the effective therapeutic module(ETM),defined as the highest corelation value with the phenotype alteration(SAQ-AF,the change in SAQ-AF at Day 30 from baseline)calculatedby WGCNA,was identifed in the population with the best effect(ASAQ-AF240),which is related to anticoagulation and regulation ofcholesterol *** assessed the modular flexbility of this ETM using the global topological D value based on Euclidean distance,which is corelated with phenotype alteration(r^(2):0.8204,P=0.019)by linear *** study identified the ant-angina therapeuticmodule in the effective population treated by the multi-target

关键词： angina injection sketch

The first data release(DR1) of the LAMOST regular survey

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-Li Luo yong-Heng Zhao Gang Zhao Li-Cai Deng Xiao-Wei Liu Yi-Peng jing Gang Wang Hao-Tong Zhang Jian-Rong Shi Xiang-Qun Cui Yao-Quan Chu Guo-Ping Li Zhong-rui Bai yue wu yan Cai Shu-yun Cao Zi-Huang Cao Jeffrey L.Carlin hai-yuan Chen Jian-Jun Chen Kun-Xin Chen Li Chen Xue-Lei Chen Xiao-yan Chen Ying Chen Norbert Christlieb Jia-ru Chu Chen-Zhou Cui Yi-Qiao Dong Bing Du Dong-Wei Fan Lei Feng Jian-Ning fu Peng Gao Xue-Fei Gong Bo-Zhong Gu yan-Xin Guo Zhan-Wen Han Bo-Liang He jin-Liang Hou yong-Hui Hou Wen Hou hong-Zhuan Hu Ning-Sheng Hu Zhong-Wen Hu Zhi-Ying Huo Lei Jia fang-Hua Jiang Xiang Jiang Zhi-Bo Jiang Ge jin Xiao Kong Xu Kong Ya-Juan Lei Ai-Hua Li Chang-Hua Li Guang-Wei Li hai-Ning Li Jian Li Qi Li Shuang Li Sha-Sha Li Xin-Nan Li yan Li Yin-Bi Li Ye-Ping Li yuan Liang Chien-Cheng Lin Chao Liu Gen-Rong Liu Guan-Qun Liu Zhi-Gang Liu Wen-Zhi Lu yu Luo Yin-Dun Mao Heidi Newberg Ji-Jun Ni Zhao-Xiang Qi yong-Jun Qi Shi-Yin Shen Huo-Ming Shi jing Song Yi-Han Song Ding-Qiang Su hong-Jun Su Zheng-hong Tang qing-Sheng Tao yuan Tian Dan Wang Da-Qi Wang Feng-Fei Wang Guo-Min Wang hai Wang hong-Chi Wang Jian Wang Jia-Ning Wang Jian-Ling Wang Jian-Ping Wang Jun-Xian Wang Lei Wang Meng-Xin Wang Shou-Guan Wang Shu-qing Wang Xia Wang Ya-Nan Wang You Wang yue-Fei Wang You-Fen Wang Peng Wei Ming-Zhi Wei hong wu Ke-Fei wu Xue-Bing wu yu-Zhong wu Xiao-Zheng Xing Ling-Zhe Xu Xin-Qi Xu yan Xu Tai-Sheng yan De-Hua yang hai-Feng yang Hui-qin yang Ming yang Zheng-Qiu Yao yong yu Hui yuan hai-Bo yuan hai-long yuan Wei-Min yuan Chao Zhai En-Peng Zhang Hua-Wei Zhang Jian-Nan Zhang Li-Pin Zhang Wei Zhang yong Zhang yan-Xia Zhang Zheng-Chao Zhang Ming Zhao fang Zhou Xu Zhou jie Zhu yong-Tian Zhu Si-Cheng zou fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in June 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in June 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

在线全文

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： He-Xin Liu yue Huang Guang-Cheng Xiao qing-Cui Bu jin-Lu Qu Shu Zhang Shuang-Nan Zhang Shu-Mei Jia fang-Jun Lu Xiang Ma Lian Tao Wei Zhang Li Chen Li-Ming Song Ti-Pei Li yu-Peng Xu Xue-Lei Cao yong Chen Cong-Zhan Liu Ce Cai Zhi Chang Gang Chen Tian-Xiang Chen Yi-Bao Chen yu-Peng Chen Wei Cui Wei-Wei Cui jing-Kang Deng yong-Wei Dong yuan-yuan Du Min-Xue fu Guan-Hua Gao He Gao Min Gao Ming-yu Ge yu-Dong Gu Ju Guan Cheng-Cheng Guo Da-Wei Han Jia Huo Lu-Hua Jiang Wei-Chun Jiang jing jin yong-jie jin Ling-Da Kong Bing Li Cheng-Kui Li Gang Li Mao-Shun Li Wei Li Xian Li Xiao-Bo Li Xu-fang Li yang-Guo Li Zheng-Wei Li Xiao-Hua Liang jing-yuan Liao Bai-Sheng Liu Guo-qing Liu hong-Wei Liu Xiao-jing Liu Yi-Nong Liu Bo Lu Xue-Feng Lu Qi Luo Tao Luo Bin Meng Yi Nang Jian-Yin nie Ge Ou Na Sai Ren-Cheng Shang Xin-Ying Song Liang Sun Ying Tan You-Li Tuo Chen Wang Guo-Feng Wang Juan Wang Ling-Jun Wang Weng-Shuai Wang yu-Sa Wang Xiang-yang Wen Bai-yang wu Bo-Bing wu Mei wu Shuo Xiao Shao-Lin Xiong He Xu Jia-Wei yang Sheng yang yan-Ji yang Yi-Jung yang Qi-Bin Yi Qian-qing Yin yuan You Ai-Mei Zhang Cheng-Mo Zhang Fan Zhang hong-Mei Zhang Juan Zhang Tong Zhang Wan-Chang Zhang Wen-Zhao Zhang Yi Zhang Yi-Fei Zhang yong-jie Zhang yuan-Hang Zhang yue Zhang Zhao Zhang Zhi Zhang Zi-Liang Zhang hai-Sheng Zhao Xiao-Fan Zhao Shi-jie Zheng Yao-Guang Zheng Deng-Ke Zhou Jian-Feng Zhou yu-Xuan Zhu Ren-Lin Zhuang yue Zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China College of Physics Sciences&Technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

在线全文

学校读者我要写书评

暂无评论

Ⅲ期非小细胞肺癌的处理:共识与争鸣

循证医学 2022年第3期22卷 129-136页

作者：吴一龙陆舜周清华张力程颖王洁汪步海胡成平林丽珠钟文昭宋勇杨农董晓荣赵健杨海虹郭卉闫小龙刘宏旭马锐林劼刘思旸陈椿王立峰周承志周明吴芳杨学宁杜瀛瀛姚煜邵阳洪少东崔久嵬全雪萍陈蓉蓉吴佳妍张嘉涛周建娅汪斌超程超王慧娟柳菁菁邬麟黄岩匡煜坤张永昌胡洁杨衿记冯卫能苏文媚范云杨帆陈明唐可京潘燚申鹏刘安文张海波梁文华周清马智勇蔡修宇刘慧陈龙飞揣少坤单建贞郑燕芳尤长宣朱晓霞李力张同梅涂海燕林武荣张绪超周鹏辉柯尊富梁会营中国抗癌协会肺癌专业委员会广东省临床试验协会/中国胸部肿瘤研究协作组广东省人民医院、广东省医学科学院、广东省肺癌研究所广州510080 上海交通大学附属胸科医院上海200030 四川大学华西医院成都610041 中山大学肿瘤防治中心广州510060 吉林省肿瘤医院长春130021 中国医学科学院肿瘤医院北京100021 南京大学医学院附属苏北人民医院江苏扬州225001 中南大学湘雅医院长沙410008 广州中医药大学第一附属医院广州510405 东部战区总医院南京210002 湖南省肿瘤医院长沙410013 华中科技大学同济医学院附属协和医院武汉430022 广州医科大学附属肿瘤医院广州510095 广州医科大学附属第一医院广州510120 西安交通大学第一附属医院西安710061 空军军医大学唐都医院西安710038 辽宁省肿瘤医院沈阳110042 昆明医科大学第二附属医院昆明650101 福建医科大学附属协和医院福州350014 南京大学医学院附属鼓楼医院南京210008 中南大学湘雅二医院长沙410011 安徽医科大学第一附属医院合肥230022 南京世和基因生物技术股份有限公司南京210032 吉林大学白求恩第一医院长春130021 上海桐树生物科技有限公司上海200444 北京吉因加科技有限公司北京102206 福建和瑞基因科技有限公司福州350207 浙江大学医学院附属第一医院杭州310031 中山大学附属第一医院广州510080 郑州大学附属肿瘤医院/河南省肿瘤医院郑州450003 复旦大学附属中山医院上海200032 佛山市第一人民医院广东佛山528000 广东医科大学附属医院广东湛江524000 中国科学院大学附属肿瘤医院/浙江省肿瘤医院杭州310022 北京大学人民医院北京100044 南方医科大学南方医院广州510515 南昌大学附属第二医院南昌330006 广东省中医院广州510120 广州燃石医学检验有限公司广州510300 南方医科大学珠江医院广州510280 陆军军医大学大坪医院重庆400042 首都医科大学附属北京胸科医院北京101149 至本医疗科技(上海)有限公司上海201114 不详

由中国抗癌协会肺癌专业委员会和广东省临床试验协会/中国胸部肿瘤研究协作组主办的“第19届中国肺癌高峰论坛”于2022年3月5日在广州顺利召开。此次论坛中,来自肺癌临床研究、转化性研究、基础研究的专家们围绕可切除/不可切除Ⅲ期非... 详细信息

由中国抗癌协会肺癌专业委员会和广东省临床试验协会/中国胸部肿瘤研究协作组主办的“第19届中国肺癌高峰论坛”于2022年3月5日在广州顺利召开。此次论坛中,来自肺癌临床研究、转化性研究、基础研究的专家们围绕可切除/不可切除Ⅲ期非小细胞肺癌(non-small cell lung cancer,NSCLC)的多学科综合治疗和生物标志物进行了深入交流和讨论,并最终达成了专家共识。

关键词： Ⅲ期非小细胞肺癌多学科综合治疗共识

在线全文

学校读者我要写书评

暂无评论

肺癌脑(膜)转移诊断治疗共识

循证医学 2018年第4期18卷 193-201页

作者：吴一龙刘晓晴毛伟敏王启鸣冯继锋刘安文胡艳萍陈海泉杨学宁揣少坤陆舜陈明许林黄飚杨衿记周建英董晓荣徐世东崔久嵬阎海王长利周彩存王绿化江本元张力宋启斌陈克能赵琼牟巨伟廖美琳陈晓媛王洁张绪超胡成平朱广迎张真发王丽萍周德祥管忠震程颖黄诚周清华陈丽昆傅小龙宋勇陈元李强钟文昭孙浩范云伍钢陈椿刘云鹏周清蔡修宇韩宝惠涂海燕王群赵明芳杨帆邬麟胡洁常建华黄云超马智勇李峻岭乔贵宾广东省人民医院广东省医学科学院广东省肺癌研究所广州510080 中国人民解放军307医院北京100071 浙江省肿瘤医院杭州310022 河南省肿瘤医院郑州450003 江苏省肿瘤医院南京210009 南昌大学第二附属医院南昌330006 湖北省肿瘤医院武汉430079 复旦大学附属肿瘤医院上海200032 广州燃石医学检验有限公司广州510300 上海交通大学附属胸科医院上海200030 浙江大学附属第一医院杭州310003 华中科技大学同济医学院附属协和医院武汉430022 哈尔滨医科大学附属肿瘤医院哈尔滨150081 吉林大学第一医院长春130021 北京泛生子基因科技有限公司北京102206 天津医科大学肿瘤医院天津300060 同济大学附属上海市肺科医院上海200433 深圳市肿瘤医院广东深圳675000 北京协和医院北京100730 中山大学肿瘤防治中心广州510060 武汉大学人民医院武汉430060 北京大学临床肿瘤学院北京100036 中国医学科学院肿瘤医院北京100021 国家食品药品监督管理总局北京100038 中南大学湘雅医院长沙410008 中日友好医院北京100029 郑州大学附属第一医院郑州450003 吉林省肿瘤医院长春130021 福建省肿瘤医院福州350014 四川大学华西医院成都610041 南京军区南京总医院南京210002 华中科技大学同济医学院附属同济医院武汉430030 四川省肿瘤医院成都610041 武汉协和肿瘤医院武汉430023 福建医科大学附属协和医院福州350001 中国医科大学附属第一医院沈阳110001 复旦大学附属中山医院上海200032 北京大学人民医院北京100044 湖南省肿瘤医院长沙410013 云南省肿瘤医院昆明650118

2018年3月8?9日,中国临床肿瘤学会(Chinese Society of Clinical Oncology,CSCO)和中国抗癌协会肺癌专业委员会联合主办了第15届“中国肺癌高峰论坛”。本次论坛的主题为“聚焦中枢神经系统转移:精确诊断,精准治疗”。晚期肺癌患者往往... 详细信息

2018年3月8?9日,中国临床肿瘤学会(Chinese Society of Clinical Oncology,CSCO)和中国抗癌协会肺癌专业委员会联合主办了第15届“中国肺癌高峰论坛”。本次论坛的主题为“聚焦中枢神经系统转移:精确诊断,精准治疗”。晚期肺癌患者往往合并脑转移,在1 000多例的肺癌尸检结果中,肺癌脑转移发生率23%~36%,是脑转移性肿瘤中最常见的类型,且通常预后较差[1]。目前肺癌脑(膜)转移的综合治疗管理和治疗结果,仍不令人满意,治疗效果不佳,中位总生存时间16个月,其中脑膜转移的患者则仅为4.5个月左右[2?5]。近10年肺癌的治疗出现了革命性的改变,但肺癌脑转移的诊断和治疗成了提高肺癌长期生存率的瓶颈。临床医师及科研工作者,应如何对脑转移进行准确及时的诊断?在众多的分型分类体系中,又该如何参考应用?如何全面地对脑转移患者的颅内/颅外病灶进行合理评估?对于伴有驱动基因敏感突变的脑转移患者群体,应怎样对待酪氨酸激酶抑制剂(tyrosine kinase inhibitor,TKI)治疗的定位和应用时机?随着血管生成抑制剂和免疫检查点Checkpoint抑制剂的应用发展,新的治疗选择在肺癌脑转移治疗应用中又该如何管理?以上都是肺癌脑转移综合管理中的疑点和难点,急需解答和形成共识以指导临床实践。本次肺癌高峰论坛,综合近年来发表的前瞻性及回顾性重要研究结果、结合我国肺癌脑转移治疗管理的实际情况,与会专家们就肺癌脑转移的综合管理进行了详细的讨论和各抒己见的争辩,最后达成了以下四点共识。

关键词：肺肿瘤脑转移循证医学共识