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Human de.tal pulp ste./stromal ce.ls in clinical practice

World Journal of Ste. Ce.ls 2024年第2期16卷 54-57页

作者： Mohamme. e.Grawish De.artme.t of Oral Biology Faculty of DentistryMansoura UniversityMansoura 35561Egypt De.artme.t of Oral Biology Faculty of Oral and Dental MedicineDelta University for Science and TechnologyMansoura 11152Egypt

De.tal pulp ste./stromal ce.ls(DPSCs)are.fibroblast-like.ne.ral cre.t-de.ive.,and multipote.t ce.ls that can diffe.e.tiate.into se.e.al *** are.re.ative.y e.sy to isolate.from he.lthy and inflame. pulps,with little.e.hical conce.ns and can be.succe.sfully cryopre.e.ve. and *** the.ape.tic e.fe.ts of DPSCs de.ive. from animal or human source. have.be.n e.te.sive.y studie. through in-vitro and in-vivo animal e.pe.ime.ts and the.findings indicate. that DPSCs are.e.fe.tive.not only for de.tal dise.se. but also for syste.ic *** that translational re.e.rch is a critical ste. through which the.fundame.tal scie.tific discove.ie. could be.translate. into applicable.diagnostics and the.ape.tics that dire.tly be.e.it humans,se.e.al clinical studie. we.e.carrie. out to ge.e.ate.e.ide.ce.for the.e.ficacy and safe.y of autoge.ous or alloge.e.c human DPSCs(hDPSCs)as a tre.tme.t modality for use.in ce.l-base. the.apy,re.e.e.ative.me.icine.de.tistry and tissue.*** clinical me.icine.hDPSCs we.e.e.fe.tive.for tre.ting acute.ische.ic stroke.and human e.foliate. de.iduous te.th-conditione. me.ium(SHe.-CM)re.aire. vascular damage.of the.corpus cave.nous,which is the.main cause.of e.e.tile.*** in clinical de.tistry,autologous SHe. was able.to re.e.ne.ate.ne.rotic de.tal pulp afte. implantation into injure. te.th,and micrografts e.riche. with autologous hDPSCs and collage. sponge.we.e.conside.e. a tre.tme.t option for human intrabony *** contrast,hDPSCs did not add a significant re.e.e.ative.e.fe.t whe. the. we.e.use. for the.tre.tme.t of post-e.traction ***-scale.clinical studie. across dive.se.populations are.still lacking to provide.robust e.ide.ce.on the.safe.y and e.ficacy of hDPSCs as a ne. tre.tme.t option for various human dise.se. including de.tal-re.ate. proble.s.

关键词： De.tal pulp ste./stromal ce.ls Human clinical studie. Re.e.e.ative.me.icine Re.e.e.ative.de.tistry Ce.l-base. the.apy

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Nove. Frame.ork for an Intrusion De.e.tion Syste. Using Multiple.Fe.ture.Se.e.tion Me.hods Base. on De.p Le.rning

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Tsinghua Scie.ce.and Te.hnology 2024年第4期29卷 948-958页

作者： A.e.M.e.jialy Mohamme. Yousuf Uddin Sultan Ahmad De.artme.t of Information Syste.s College of Computer Engineering and SciencesPrince Sattam Bin Abdulaziz UniversityAlkharjSaudi Arabia De.artme.t of Compute. Scie.ce College of Computer Engineering and SciencesPrince Sattam Bin Abdulaziz UniversityAlkharjSaudi Arabiaand also with University Center for Research and Development(UCRD)Department of Computer Science and EngineeringChandigarh UniversityPunjabIndia

Intrusion de.e.tion syste.s (IDSs) are.de.loye. to de.e.t anomalie. in re.l time. The. classify a ne.work’s incoming traffic as be.ign or anomalous (attack). An e.ficie.t and robust IDS in software.de.ine. ne.works is an ine.itable.compone.t of ne.work se.urity. The.main challe.ge. of such an IDS are.achie.ing ze.o or e.tre.e.y low false.positive.rate. and high de.e.tion rate.. Inte.ne. of Things (IoT) ne.works run by using de.ice. with minimal re.ource.. This situation make. de.loying traditional IDSs in IoT ne.works unfe.sible. Machine.le.rning (ML) te.hnique. are.e.te.sive.y applie. to build robust IDSs. Many re.e.rche.s have.utilize. diffe.e.t ML me.hods and te.hnique. to addre.s the.above.challe.ge.. The.de.e.opme.t of an e.ficie.t IDS starts with a good fe.ture.se.e.tion proce.s to avoid ove.fitting the.ML mode.. This work propose. a multiple.fe.ture.se.e.tion proce.s followe. by classification. In this study, the.Software.de.ine. ne.working (SDN) datase. is use. to train and te.t the.propose. mode.. This mode. applie. multiple.fe.ture.se.e.tion te.hnique. to se.e.t high-scoring fe.ture. from a se. of fe.ture.. Highly re.e.ant fe.ture. for anomaly de.e.tion are.se.e.te. on the.basis of the.r score. to ge.e.ate.the.candidate.datase.. Multiple.classification algorithms are.applie. to the.candidate.datase. to build mode.s. The.propose. mode. e.hibits conside.able.improve.e.t in the.de.e.tion of attacks with high accuracy and low false.positive.rate., e.e. with a fe. fe.ture. se.e.te..

关键词： random fore.t fe.ture.se.e.tion de.ision tre. software.de.ine. ne.work logistic re.re.sion intrusion de.e.tion syste. XGB classifie. AdaBoost

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The.e.fe.ts of local variations in conditions on carbon storage.and re.e.se.in the.contine.tal mantle

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National Scie.ce.Re.ie. 2024年第6期11卷 22-36页

作者： Ste.he. F.Fole. Chunfe. Che. Dorrit e.Jacob School of Natural Scie.ce. Macquarie University Re.e.rch School of e.rth Scie.ce. Australian National University State.Ke. Laboratory of Ge.logical Proce.se. and Mine.al Re.ource. School of Earth Sciences China University of Geosciences

Re.e.t advance. indicate.that the.amount of carbon re.e.se. by gradual de.assing from the.mantle.ne.ds to be.re.ise. upwards, whe.e.s the.carbon supplie. by plume. may have.be.n ove.e.timate. in the.*** in rock type. and oxidation state.may be.ve.y local and e.e.t strong influe.ce. on carbon storage.and re.e.se.me.hanisms. De.p subduction may be.pre.e.te. by diapirism in thick se.ime.tary package.,whe.e.s carbonate. in thinne. se.ue.ce. may be.subducte.. Carbonate. store. in the.mantle.transition zone.will me.t whe. the. he.t up, re.ognize. by couple. stable.isotope.syste.s(e.g. Mg, Zn, Ca). The.e.is no single.‘mantle.oxyge. fugacity’, particularly in the.the.mal boundary laye.(TBL) and lowe.most lithosphe.e. whe.e.ve.y local mixture. of rock type. coe.ist. Carbonate.rich me.ts from e.the. subduction or me.ting of the.uppe.most asthe.osphe.e.trap carbon by re.ox fre.zing or as carbonate.rich dyke. in this zone. De.ply de.ive., re.uce. me.ts may form furthe. diamond re.e.voirs, re.ognize. as polycrystalline.diamonds associate. with we.ste.itic silicate.mine.als. Carbon is re.e.se. by e.the. e.ge.drive. conve.tion,which te.rs se.tions of the.TBL and lowe. lithosphe.e.down so that the. me.t by a mixture.of he.ting and oxidation, or by late.al adve.tion of solids be.e.th rifts. Both me.hanisms ope.ate.at ste.s in lithosphe.e.thickne.s and re.ult in carbonate.rich me.ts, e.plaining the.spatial association of craton e.ge. and carbonate.rich magmatism. High-pre.sure.e.pe.ime.ts on individual rock type., and incre.singly on re.ctions be.we.n rocks and me.ts, are.fine.tuning our unde.standing of proce.se. and turning up une.pe.te. re.ults that are.not se.n in studie. of single.rocks. Future.re.e.rch should conce.trate.on e.ucidating local variations and inte.rating the.e.with the.inte.pre.ation of ge.physical signals. Global conce.ts such as ave.age.se.ime.t compositions and a uniform mantle.oxidation state.are.not appropriate.for small-scale.proce.se.; an incre.

关键词： lithosphe.ic mantle carbonate.me.ts de.p carbon cycle craton de.truction contine.tal rifts

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e.aluation of the.se.smic be.avior of re.nforce. concre.e.structure. with flat slab-column gravity frame.and she.r walls through nonline.r analysis me.hods

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e.rthquake.e.gine.ring and e.gine.ring Vibration 2024年第3期23卷 713-726页

作者： M.A.Najafgholipour S.He.darian Radbakhsh e.e.fani De.artme.t of Civil and e.vironme.tal e.gine.ring Shiraz University of TechnologyShiraz ***Iran De.artme.t of Building Civiland Environmental EngineeringConcordia UniversityMontréal H3G 1M8Canada

This pape. pre.e.ts an inve.tigation of the.se.smic be.avior of re.nforce. concre.e.RC)structure. in which she.r walls are.the.main late.al load-re.isting e.e.e.ts and the.participation of flat slab floor syste.s is not conside.e. in the.se.smic de.ign *** this re.ard,the.be.avior of six prototype.structure.(with diffe.e.t he.ghts and plan layouts)is inve.tigate. through nonline.r static and time.history analyse.,imple.e.te. in the.Ope.Se.s *** re.ults of the.analyse. are.pre.e.te. in te.ms of the.be.avior of the.slab-column conne.tions and the.r mode.of failure.at diffe.e.t loading ***,the.global re.ponse.of the.buildings is discusse. in te.ms of some.parame.e.s,such as late.al ove.stre.gth due.to the.gravity flat slab-column *** to the.nonline.r static analyse.,in structure. in which the.slab-column conne.tions we.e.de.igne. only for gravity loads,the.slab-column conne.tions e.hibite. a punching mode.of failure.e.e. in the.e.rly stage. of ***,the.punching failure.was e.iminate. in structure. in which a minimum transve.se.re.nforce.e.t re.omme.de. in ACI 318(2019)was provide. in the.slabs at joint ***,de.pite.ne.le.ting the.contribution of gravity flat slab-column frame. in the.late.al load re.istance.of the.structure.,a re.ative.y significant ove.stre.gth was impose. on the.structure. by the.gravity frame..

关键词： RC flat slab-column frame. se.smic be.avior nonline.r analysis time.history analysis

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e.ission colour tuning in KLnF_(4):Yb^(3+),e.^(3+)/Ho^(3+)phosphor

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Journal of Rare.e.rths 2024年第1期42卷 57-65,I0002页

作者： Janani K Gayathri e.Vijayatha V Ramasubramanian S Thiyagarajan P De.artme.t of Scie.ce.and Humanitie. Nehru Institute of TechnologyKaliapuramThirumalayampalayamCoimbatoreIndia De.artme.t of Scie.ce. Amrita School of Physical SciencesAmrita Vishwa VidyapeethamCoimbatoreIndia De.artme.t of Physics Anna UniversityChennaiIndia

KLnF_(4):Yb^(3+),e.^(3+)/Ho^(3+)(Ln=Y,Yb,Gd)phosphors we.e.pre.are. by solid-state.re.ction *** e.ch of the.Yb^(3+)/e.^(3+)and Yb^(3+)/Ho^(3+)co-dope. phosphors inde.e.de.tly,phase.confirmation and morphological e.amination we.e.accomplishe. using the.X-ray diffraction te.hnique.and scanning e.e.tron microscope.analysis.X-ray photoe.e.tron spe.troscopy analysis shows the.charge.state.and e.iste.ce.of lanthanide. and *** lumine.ce.ce.e.issions of gre.n and re. colour we.e.de.e.te. for the.synthe.ize. *** change. in the.upconve.te. e.ission inte.sitie. and colour output pe.taining to the.change.of the.lanthanide.host matrix along with dopants we.e.inve.tigate. for the.pre.are. *** the.upconve.sion lumine.ce.ce.e.bium-dope. sample. e.hibit a pre.ominance.of re. e.ission while.holmium-dope. sample. display a pre.ale.ce.of gre.n *** rare.e.rth e./Ho dope. KYbF4shows strong re. e.ission compare. to othe. ***_(4):Yb,e./Ho e.hibits re.ative.y significant gre.n upconve.rsion e.issions,while.Yb,e.-dope. KGdF_(4)host displays a 10-fold incre.se.in gre.n/re. e.ission ratio with an incre.se.in the.input powe. of 20-780 *** photolumine.ce.ce.studie. and de.ay curve.analysis we.e.carrie. out using UV light e.citation for the.de.e.ope. phosphors.A highe. life.ime.of 2.2 ms was me.sure. for the.downshifting re. e.ission in the.Ho dope. KYbF_(4)*** study sugge.ts a pote.tial for colour tunability in the.upconve.sion and downshifting e.issions through host modifications to the.fluoride.phosphor.

关键词： Rare.e.rths e.e.gy transfe. upconve.sion Downshifting Colour coordinate.

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儿童期发病的系统性红斑狼疮的初期表现:法国的多中心研究

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世界核心医学期刊文摘（儿科学分册） 2005年第10期1卷 56-56页

作者： Bade.-Me.nie. B. Arme.gaud J.B. haddad e. 李丹 Se.v . de.Pêdiat. Gên. Hpital de Bicêtre 78 rue du Gên. Leclerc 94276 Le Kre mlin Bicêtre France Dr.

Obje.tive. To de.cribe.the.clinical and laboratory manife.tations of childhood -onse. syste.ic lupus e.ythe.atosus (SLe. at pre.e.tation. Study de.ign: This r e.rospe.tive.Fre.ch multice.te. study involve. 155 patie.ts in whom SLe.de.e.ope.d be.ore.the.age.of 16 ye.rs. Me.n patie.t age.at onse. was 11.5 ±2.5 ye.rs (ra nge. 1.5-16 ye.rs). The.fe.ale.to male.ratio was 4.5. Re.ults: The.most common initial manife.tations we.e.he.atologic (72%), cutane.us (70%), musculoske.e.a l (64%), re.al (50%), and fe.e. (58%). Thirty-two pe.ce.t of childre. had at ypical symptoms, mainly including abdominal involve.e.t in 26 patie.ts, which le.ad to ne.ative.laparotomy re.ults for pre.ume. appe.dicitis. Se.e.e.re.al, ne.ro logic, he.atologic, abdominal, cardiac, pulmonary, thrombotic, and/or cutane.us manife.tations occurre. within the.first month afte. the.diagnosis in 40%of pat ie.ts. The.me.n e.ythrocyte.se.ime.tation rate.was 72 ±29 mm/h, and the.me.n C -re.ctive.prote.n value.22 ±21 mg/L. Antinucle.r antibodie. an, anti-double.s trande. DNA antibodie., and low C3 or C4 le.e. we.e.re.rie.e. in 97%, 93%, and 78 %of patie.ts, re.pe.tive.y. Conclusion: Initial manife.tations of childhood -onse. SLe.are.dive.se.and ofte. se.e.e. The.diagnosis of SLe.should be.promptl y conside.e. in any fe.rile.adole.ce.t with une.plaine. organ involve.e.t, e.pe. ially whe. associate. with an incre.se. e.ythrocyte.se.ime.tation rate.

关键词：系统性红斑狼疮童期肺部表现红细胞沉降抗核抗体血栓形成发病年龄腹部症状研究设计 DNA

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A ne. me.hod for pre.ise.optical me.sure.e.ts of the.sub-micron he.ght of le.itation of drople. cluste.s

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Particuology 2024年第4期87卷 173-178页

作者： Ale.ande. A.Fe.ore.s e.uard e.Kolmakov Le.nid A.Dombrovsky Unive.sity of Tyume. 6 Volodarskogo StTyumen625003Russia e.gine.ring Faculty Ariel UniversityP0.B.3407000ArielIsrael Joint Institute.for High Te.pe.ature. 17A Krasnokazarmennaya StMoscow111116Russia

Drople. cluste.s le.itating ove. the.locally he.te. wate. surface.are.conside.e. a ve.y promising phe.nome.on of microfluidics for the.pote.tial use.of the.drople.s as unique.microre.ctors for microbio-logical e.pe.ime.ts.A ne. optical me.hod is sugge.te. for pre.ise.me.sure.e.ts of the.sub-micron le.itation he.ght of single.*** me.hod is base. on the.analysis of variable.colors of the.inte.-fe.e.ce.halo around the.*** the.first time.it is possible.to me.sure.the.e.tre.e.y low downward ve.ocity of drople.s,which grow due.to ste.m *** ve.ocity was found to be.5-8 nm/*** he.ght of the.le.itation of various drople.s just be.ore.the.r coale.ce.ce.with a laye. of wate. was also *** me.sure.e.ts might be.use. for the.ve.ification of sophisticate. mode.s for the.drople. le.itation to be.de.e.ope. for a ve.y thin laye. of humid air unde. the.drople. whe. the.Knudse. e.fe.t should be.take. into account.

关键词： Pre.ise.me.sure.e.ts Inte.fe.ome.ric me.hod Drople. cluste. Le.itation he.ght

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e.fe.tive.e.s of ive.me.tin mass drug administration in the.control of soil-transmitte. he.minth infe.tions in e.de.ic populations: a syste.atic re.ie. and me.a-analysis

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Infe.tious Dise.se. of Pove.ty 2024年第1期13卷 1-15页

作者： Brandon Le.Naomi e.Clarke.Nicolas Le.rand Susana Vaz Ne.y The.Kirby Institute University of New South WalesLevel 6Wallace Wurth BuildingSydneyNSW2052Australia

Background Curre.t soil-transmitte. he.minth(STH)control guide.ine. e.dorse.the.use.of albe.dazole.or me.e.-dazole.for school-base. targe.e. pre.e.tive.che.othe.apy(PC),ye. the.r re.uce. e.ficacy against Strongyloide. ste.c-oralis and Trichuris trichiura pre.e.ts significant *** e.ide.ce.indicate. that community-wide.PC[or mass drug administration(MDA)]using ive.me.tin,commonly use. in othe. ne.le.te. tropical dise.se.NTD)control programs,may play an important role.in controlling the.e.*** conducte. a syste.atic re.ie. and me.a-analysis to e.aluate.the.e.fe.tive.e.s of ive.me.tin PC in re.ucing STH pre.ale.ce.in e.de.ic *** We.se.rche. Pubme.,e.BASe.and We. of Scie.ce.on Fe.ruary 14,2023,for studie. that inve.tigate. the.e.fe.tive.e.s of ive.me.tin PC,e.the. alone.or in combination with othe. anthe.mintic drugs,on STH infe.-tions,and provide. a me.sure.of STH pre.ale.ce.be.ore.and afte. *** calculate. poole. pre.ale.ce.re.uctions for e.ch STH using random-e.fe.ts *** protocol is available.on PROSPe.O(re.istration numbe. CRD42023401219).Re.ults A total of 21 we.e.e.igible.for the.syste.atic re.ie.,of which 15 we.e.e.igible.for *** studie. de.ive.e. ive.me.tin through *** poole. pre.ale.ce.re.uction of *** following MDA with ive.me.-tin alone.was 84.49%(95%CI:54.96-94.66)across five.studie. and 81.37%(95% CI:61.62-90.96)across se.e. studie. with or without *** pre.ale.ce.re.uction of *** was 49.93%(95%CI:18.23-69.34)across five.studie. with ive.me.tin alone.and 89.40%(95%CI:73.66-95.73)across thre. studie. with the.addition of *** was high he.e.oge.e.ty for all synthe.e.(I^(2)>65%).Conclusions This study unde.score. the.ke. role.of ive.me.tin-base. MDA in addre.sing limitations in curre.t global STH guide.ine. in te.ms of limite. e.ficacy against *** and *** on the.e.findings,re.ising inte.-national STH guide.ine. to include.i

关键词： Soil-transmitte. he.minths Ive.me.tin Albe.dazole Mass drug administration Pre.e.tive.che.othe.apy

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Ne.natal Dire.t Rigid Laryngoscopy and Bronchoscopy: A Ne.r Miss

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Ope. Journal of Ane.the.iology 2024年第4期14卷 126-130页

作者： De.nis e. Fe.e.man Mark Krone.fe.d Jacob Sutton Gil Zoizne. e.an P. Salant De.artme.t of Ane.the.iology Maimonides Medical Center New York USA Rutge.s Robe.t Wood Johnson Unive.sity Hospital New Brunswick USA Me.r Hospital Clalit Health Services Kefar Sava Israel

Airway manage.e.t is a skill ne.e.sary for he.lthcare.provide.s who manage.patie.ts. Intubation is a skill that both ane.the.iologists and inte.sivists use.daily. We.pre.e.t a case.of a ne.nate.that de.e.ope. significant worse.ing stridor afte. a succe.sful intubation for a he.nia re.air. Afte. 4 intubation atte.pts, with e.sy visualization of the.vocal cords and unsucce.sful place.e.t of the.e.dotrache.l tube. the.patie.t was e.e.ge.tly brought to the.ope.ating room for e.aluation.

关键词： Ne.nate Dire.t Laryngoscopy Intubation

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Adipose.de.ive. re.e.e.ative.the.apie. for the.tre.tme.t of kne. oste.arthritis

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World Journal of Ste. Ce.ls 2024年第4期16卷 324-333页

作者： Ilias e.e.anome.itakis Wasim S Khan Division of Trauma and Orthopae.ic Surge.y Addenbrooke’s HospitalCambridge University Hospitals NHS Foundation TrustCambridge CB20QQUnited Kingdom Division of Trauma and Orthopae.ic Surge.y Department of SurgeryUniversity of CambridgeCambridge CB20QQUnited Kingdom

Kne. oste.arthritis is a de.e.e.ative.condition with a significant dise.se.burde. and no dise.se.modifying *** tre.tme.t ultimate.y re.uire. joint *** capable.of re.e.e.ating cartilage.could significantly re.uce.financial and clinical *** re.e.e.ative.pote.tial of me.e.chymal stromal ce.ls(MSCs)has be.n e.te.sive.y studie. in the.conte.t of kne. *** has yie.de. promising re.ults in human studie.,and is like.y a product of immunomodulatory and chondroprote.tive.biomole.ule. produce. by MSCs in re.ponse.to ***-de.ive. MSCs(ASCs)are.be.oming incre.singly popular owing to the.r re.ative.e.se.of isolation and high prolife.ative.*** vascular fraction(SVF)and micro-fragme.te. adipose.tissue.MFAT)are.produce. by the.e.zymatic and me.hanical disruption of adipose.tissue.*** avoids e.pansion of isolate. ASCs e. vivo and the.r composition of he.e.oge.e.us ce.l populations,including immune.ce.ls,may pote.tiate.the.re.arative.function of *** this e.itorial,we.comme.t on a multice.te. randomize. trial re.arding the.e.ficacy of MFAT in tre.ting kne. *** discuss the.study’s findings in the.conte.t of e.e.ging e.ide.ce.re.arding adipose.de.ive. re.e.e.ative.*** unde.lying me.hanism of action of ASCs is propose. while.drawing important distinctions be.we.n the.prope.tie. of isolate. ASCs,SVF,and MFAT.

关键词： Kne. oste.arthritis Me.e.chymal stromal ce.ls Adipose.tissue Stromal vascular fraction Micro-fragme.te. adipose.tissue Re.e.e.ation

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