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World Journal of Gastroenterology 2007年第8期13卷 1214-1220页

作者： ming-Fu Yin Li-Hua Lian Dong-ming Piao Ji-Xing Nan Key Laboratory of Organism Functional Factors of the Changbai Mountain (Yanbian University) Ministry of Education and College of Pharmacy Yanbian University Yanji 133002 Jilin Province China College of Pharmacy Yanbian University Yanji 133002 Jilin Province China Department of Pathology the Affiliated Hospital Medical College Yanbian University Yanji 133002 Jilin Province China

AIM： To investigate the therapeutic effect of tetrandrine on liver fibrosis induced by thioacetamide in rats in vivo and in vitro. METHODS： In vitro study： we investigated the effect of tetrandrine on the apoptosis of rat hepatic stellate cells transformed by simian virus 40 （T-HSC/CI-6）, which retains the features of activated cells. In vivo study： hepatic fibrosis was induced in rats by thioacetamide. Tetrandrine was given orally to rats at doses of 5, 10 or 20 mg/kg for 4 wk compared with intraperitoneal injection of interferon-r. RESULTS： In vitro study： 5, 10 or 25 μg/mL of tetrandrine-induced activation of caspase-3 in t-HSC/CI-6 cells occurred dose-dependently. In vivo study： tetrandrine treatment as well as interferon-r significantly ameliorated the development of fibrosis as determined by lowered serum levels of aspartate aminotransferase （AST）, alanine aminotransferase （ALT）, total bilirubin （T-Bil） and the levels of liver hydroxyproline （Hyp）, hyaluronic acid （ha）, laminin （LN） and also improved histological findings. The effects of tetrandrine at the concentration of 20 mg/kg were better than the other concentration groups. CONCLUSION： Tetrandrine promotes the apoptosis of activated HSCs in vitro. Tetrandrine administration can prevent liver fibrosis and liver damage induced by thioacetamide in rats in vivo, indicating that it might exert a direct effect on rat HSCs.

关键词： Tetrandrine Apoptosis Caspase-3 Liver fibrosis Thioacetamide

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正常成人发不同元音时口腔压力和鼻流量研究

听力学及言语疾病杂志 2016年第2期24卷 126-129页

作者： Kim ha-kyung 段弘艳惠芬芬万勤黄昭鸣华东师范大学言语听觉科学教育部重点实验室上海200062 华东师范大学言语听觉康复科学系

目的探讨正常成年人发不同元音时口腔压力和鼻流量值的差异,并分析二者之间是否有相关性。方法对30例正常成人(男女各半)在发/pa/、/pi/、/pu/时测量其口腔压力,在发/a/、/i/、/u/时测量其鼻流量,对结果进行统计学分析。结果 1男性发/pa... 详细信息

目的探讨正常成年人发不同元音时口腔压力和鼻流量值的差异,并分析二者之间是否有相关性。方法对30例正常成人(男女各半)在发/pa/、/pi/、/pu/时测量其口腔压力,在发/a/、/i/、/u/时测量其鼻流量,对结果进行统计学分析。结果 1男性发/pa/、/pi/、/pu/时口腔压力平均值分别为4.53±0.70、5.21±0.80、5.87±1.45cm H2O,女性分别为4.09±0.30、4.47±0.30、4.77±0.32cm H2O,男性较女性高(P0.05),不同元音间鼻流量后差异有统计学意义(P<0.05),但不同性别和不同元音间无交互作用。3口腔压力和鼻流量值呈弱相关(r=-0.240)。结论不同性别成人发相同元音时,男性的平均口腔压力值较女性高,但男女之间鼻流量值差异无统计学意义;相同性别不同元音间口腔压力和鼻流量值差异有统计学意义;口腔压力与鼻流量弱相关。

关键词：发声阈压口腔压力鼻流量元音

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一类连续小波的构造及其性质

河北大学学报（自然科学版） 2006年第4期26卷 341-344页

作者：田大增哈明虎田学东河北大学物理科学与技术学院河北保定071002 河北大学数学与计算机学院河北保定071002

小波分析是国际上新兴的一个前沿研究课题,已成为众多学科共同关注的热点.小波函数的构造问题是小波理论分析与应用研究的基础.文章提出了一类连续性小波函数的构造方法,同时证明了其满足允许条件,并利用该方法构造出了几个小波函数,同... 详细信息

小波分析是国际上新兴的一个前沿研究课题,已成为众多学科共同关注的热点.小波函数的构造问题是小波理论分析与应用研究的基础.文章提出了一类连续性小波函数的构造方法,同时证明了其满足允许条件,并利用该方法构造出了几个小波函数,同时利用MATLAB程序绘出了相应的小波函数及其Fourier变换(频谱)图.

关键词：连续小波允许条件小波构造 Fourier变换

Tillage and straw mulching impacts on grain yield and water use efficiency of spring maize in Northern Huang–Huai–hai Valley

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The Crop Journal 2015年第5期3卷 445-450页

作者： Zhiqiang Tao Congfeng Li Jingjing Li Zaisong Ding Jie Xu Xuefang Sun Peilu Zhou ming Zhao Institute of Crop Science Chinese Academy of Agricultural Sciences/Key Laboratory of Crop Physiology and Ecology Ministry of Agriculture

A two-year field experiment(2012–2013) was conducted to investigate the effects of two tillage methods and five maize straw mulching patterns on the yield, water consumption,and water use efficiency(WUE) of spring maize(Zea mays L.) in the northern Huang–Huai–hai valley of China. Compared to rotary tillage, subsoil tillage resulted in decreases in water consumption by 6.3–7.8% and increases in maize yield by 644.5–673.9 kg ha-1, soil water content by 2.9–3.0%, and WUE by 12.7–15.2%. Chopped straw mulching led to higher yield,soil water content, and WUE as well as lower water consumption than prostrate whole straw mulching. Mulching with 50% chopped straw had the largest positive effects on maize yield, soil water content, and WUE among the five mulching treatments. Tillage had greater influence on maize yield than straw mulching, whereas straw mulching had greater influence on soil water content, water consumption, and WUE than tillage. These results suggest that 50% chopped straw mulching with subsoil tillage is beneficial in spring maize production aiming at high yield and high WUE in the Huang–Huai–hai valley.

关键词： Northern Huang–Huai–hai valley Spring maize croppi

Estimates of N_2O Emissions and Mitigation Potential from a Spring Maize Field Based on DNDC Model

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Journal of Integrative Agriculture 2012年第12期11卷 2067-2078页

作者： LI Hu QIU Jian-jun Wang Li-gang XU ming-yi LIU Zhi-qiang Wang Wei Key Laboratory of Non-Point Source Pollution Control Ministry of Agriculture/CAAS-UNH Joint Laboratory for Sustainable Agro-Ecosystems Research/Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural Sciences Dalian Academy of Agricultural Sciences

Agricultural production plays an important role in affecting atmospheric nitrous oxide （N20） concentrations. Field measurements were conducted in Dalian City, Liaoning Province in Northeast China from two consecutive years （2009 and 2010） to estimate NzO emissions from a spring maize field, a main cropping system across the Chinese agricultural regions. The observed flux data in conjunction with the local climate, soil and management information were utilized to test a process-based model, DeNitrification-DeComposition （DNDC）, for its applicability for the cropping system. The validated DNDC was then used for exploring strategies to reduce N20 emissions from the target field. The results showed that the major N20 pulse emissions occurred with duration of about 3-5 d after fertilizer application in both years 2009 and 2010, which on average accounted for about 60% of the total N20 emissions each year. Rainfall and fertilizer application were the major factors influencing the N20 emissions from spring maize field. The average N20 flUXeS from the CK （control plot, without fertilization） and FP （traditional chemical N fertilizer） treatments were 23.1 and 60.6 gg m-2 h-~ in 2009, respectively, and 21.5 and 64.3 gg m-2 h-~ in 2010, respectively. The emission factors （EFs） of the applied N fertilizer （270 kg N ha-1） as N20- N were 0.62% in 2009 and 0.77% in 2010, respectively. The comparison of modeled daily NzO emission fluxes against observations indicated that the DNDC model had a good performance even if without adjusting the internal parameters. The modeled results showed that management practices such as no-till, changing timing or rate of fertilizer application, increasing residue incorporation, and other technically applicable measures could effectively reduce N20 emissions from the tested fields. Our study indicated that avoiding application of N fertilizers at heavy rainfall events or splitting the fertilizer into more applications would be the most feasible appr

关键词： spring maize N20 DNDC mitigation measures Northeast China

The evolution,pathogenicity and transmissibility of quadruple reassortant H1N2 swine influenza virus in China:A potential threat to public health

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Virologica Sinica 2024年第2期39卷 205-217页

作者： Xinxin Cui Jinhuan Ma Zifeng Pang Lingzhi Chi Cuishan Mai hanlin Liu ming Liao hailiang Sun College of Veterinary Medicine South China Agricultural UniversityGuangzhou510642China Key Laboratory of Zoonosis Control and Prevention of Guangdong Province South China Agricultural UniversityGuangzhou510642China National and Regional Joint Engineering Laboratory for Medicament of Zoonosis Prevention and Control South China Agricultural UniversityGuangzhou510642China Shandong Vocational Animal Science and Veterinary College Weifang261061China Institute of Animal Health Guangdong Academy of Agricultural SciencesGuangzhou510640China

Swine are regarded as“intermediate hosts”or“mixing vessels”of influenza viruses,capable of generating strains with pandemic *** 2020 to 2021,we conducted surveillance on swine H1N2 influenza(swH1N2)viruses in swine farms located in Guangdong,Yunnan,and Guizhou provinces in southern China,as well as Henan and Shandong provinces in northern *** systematically analyzed the evolution and pathogenicity of swH1N2 isolates,and characterized their replication and transmission *** isolated viruses are quadruple reassortant H1N2 viruses containing genes from pdm/09 H1N1(PB2,PB1,PA and NP genes),triple-reassortant swine(NS gene),Eurasian Avian-like(ha and M genes),and recent human H3N2(NA gene)*** NA,PB2,and NP of SW/188/20 and SW/198/20 show high gene similarities to A/Guangdong/Yue Fang277/2017(H3N2).The ha gene of swH1N2 exhibits a high evolutionary *** five swH1N2 isolates replicate efficiently in human,canine,and swine cells,as well as in the turbinate,trachea,and lungs of mice.A/swine/Shandong/198/2020 strain efficiently replicates in the respiratory tract of pigs and effectively transmitted among ***,these current swH1N2 viruses possess zoonotic potential,highlighting the need for strengthened surveillance of swH1N2 viruses.

关键词： Swine influenza virus(SIV) H1N2 Evolution Replication Pathogenicity Zoonotic potential

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P-平均对称差度量的可分性

模糊系统与数学 1999年第4期13卷 46-52页

作者：李法朝哈明虎翟建仁河北科技大学基础部河北石家庄050018 河北大学数学系河北保定071002

引入台型Fuzzy 数的概念,证明了台型Fuzzy 数全体E1T 在Fuzzy 数空间E1

关键词： P-平均对称差度量可分性台型模糊数度量空间

Response of soil Olsen-P to P budget under different long-term fertilization treatments in a fluvo-aquic soil

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Journal of Integrative Agriculture 2019年第3期18卷 667-676页

作者： ZHang Wei-wei ZhaN Xiao-ying ZHang Shu-xiang Khalid hamdan Mohamed Ibrahima XU ming-gang Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural Sciences College of Urban and Environmental Sciences Peking University

The concentration of soil Olsen-P is rapidly increasing in many parts of China, where P budget(P input minus P output) is the main factor influencing soil Olsen-P. Understanding the relationship between soil Olsen-P and P budget is useful in estimating soil Olsen-P content and conducting P management strategies. To address this, a long-term experiment(1991–2011) was performed on a fluvo-aquic soil in Beijing, China, where seven fertilization treatments were used to study the response of soil Olsen-P to P budget. The results showed that the relationship between the decrease in soil Olsen-P and P deficit could be simulated by a simple linear model. In treatments without P fertilization(CK, N, and NK), soil Olsen-P decreased by 2.4, 1.9, and 1.4 mg kg^(–1) for every 100 kg ha^(–1) of P deficit, respectively. Under conditions of P addition, the relationship between the increase in soil Olsen-P and P surplus could be divided into two stages. When P surplus was lower than the range of 729–884 kg ha^(–1), soil Olsen-P fluctuated over the course of the experimental period with chemical fertilizers(NP and NPK), and increased by 5.0 and 2.0 mg kg^(–1), respectively, when treated with chemical fertilizers combined with manure(NPKM and 1.5 NPKM) for every 100 kg ha^(–1) of P surplus. When P surplus was higher than the range of 729–884 kg ha^(–1), soil Olsen-P increased by 49.0 and 37.0 mg kg^(–1) in NPKM and 1.5 NPKM treatments, respectively, for every 100 kg ha^(–1) P surplus. The relationship between the increase in soil Olsen-P and P surplus could be simulated by two-segment linear models. The cumulative P budget at the turning point was defined as the "storage threshold" of a fluvo-aquic soil in Beijing, and the storage thresholds under NPKM and 1.5 NPKM were 729 and 884 kg ha^(–1)P for more adsorption sites. According to the critical soil P values(CPVs) and the relationship between soil Olsen-P and P budget, the quantity of P fertilizers for winter wheat could be increased

关键词： long-term fertilization fluvo-aquic soil Olsen-P P budget critical soil P value

Spectral Analysis of the Flare of 1998 November 11 based on the Multi-cloud Model

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Chinese Journal of Astronomy and Astrophysics 2002年第1期2卷 92-102页

作者： Xiao－MaGu ming－DeDing YunnanObservatory NationalAstronomicalObservatoriesCASKunming650011 DepartmentofAstronomy NanjingUniversityNanjing210093

We have obtained 2D spectra of ha and CaII λ8542A for the flare of 1998 November 11, and derived its 2D velocity field and integrated intensity field. The velocity distribution shows that the red-shift and blue-shift velocities lie respectively in the northern and southern parts of the flare and that the maximum velocity seems to be located in two footpoints of the flare loop system. The integrated intensity distribution shows that the CaIIλ8542A line is formed at a lower height than the ha line, we used 'multi-cloud model' (MCM) to obtain four parameters for the two lines (Doppler width, △λD, Doppler shift, △λ0, line source function, S, and optical depth at the line center, TO). We also estimated the column number densities of hydrogen at the second level, N2, and of the ionized calcium at the third level, N3, as well as the kinetic temperature, Tc. The wide Hα profile at the loop top may be explained by an overlapping of two or more elementary profiles. It is shown that the uncertainty in calibration does not affect the derived Doppler shift and line broadening, only the source function and optical depth.

关键词： Sun: activity-Sun: flares-methods: data analysis