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Attention-Enhanced Voice Portrait Model Using Generative Adversarial Network

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Computers, Materials & Continua 2024年第4期79卷 837-855页

作者： Jingyi Mao Yuchen Zhou YifanWang Junyu li Ziqing liu fanliang Bu School of Information Network Security People’s Public Security University of ChinaBeijing100038China

Voice portrait technology has explored and established the relationship between speakers’ voices and their facialfeatures, aiming to generate corresponding facial characteristics by providing the voice of an unknown *** to its powerful advantages in image generation, Generative Adversarial Networks (GANs) have now beenwidely applied across various fields. The existing Voice2face methods for voice portraits are primarily based onGANs trained on voice-face paired datasets. However, voice portrait models solely constructed on GANs facelimitations in image generation quality and struggle to maintain facial similarity. Additionally, the training processis relatively unstable, thereby affecting the overall generative performance of the model. To overcome the abovechallenges,wepropose a novel deepGenerativeAdversarialNetworkmodel for audio-visual synthesis, namedAVPGAN(Attention-enhanced Voice Portrait Model using Generative Adversarial Network). This model is based ona convolutional attention mechanism and is capable of generating corresponding facial images from the voice ofan unknown speaker. Firstly, to address the issue of training instability, we integrate convolutional neural networkswith deep GANs. In the network architecture, we apply spectral normalization to constrain the variation of thediscriminator, preventing issues such as mode collapse. Secondly, to enhance the model’s ability to extract relevantfeatures between the two modalities, we propose a voice portrait model based on convolutional attention. Thismodel learns the mapping relationship between voice and facial features in a common space from both channeland spatial dimensions independently. Thirdly, to enhance the quality of generated faces, we have incorporated adegradation removal module and utilized pretrained facial GANs as facial priors to repair and enhance the clarityof the generated facial images. Experimental results demonstrate that our AVP-GAN achieved a cosine similarity of0.511, ou

关键词： Cross-modal generation GANs voice portrait technology face synthesis

非农职业经历、土地流转对家庭农场主农业生产生态自觉性的影响效应

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西北农林科技大学学报（社会科学版） 2024年第2期24卷 115-126页

作者：王林蔚霍学喜孔荣西北农林科技大学经济管理学院陕西杨凌712100

基于陕西省564户种植业家庭农场微观调研数据,在考虑样本选择偏差和家庭农场异质性基础上,采用倾向匹配得分(PSM)模型探究非农职业经历对家庭农场主农业生产生态自觉性的净效应,并运用中介效应模型分析土地流转视角下非农职业经历影响... 详细信息

基于陕西省564户种植业家庭农场微观调研数据,在考虑样本选择偏差和家庭农场异质性基础上,采用倾向匹配得分(PSM)模型探究非农职业经历对家庭农场主农业生产生态自觉性的净效应,并运用中介效应模型分析土地流转视角下非农职业经历影响家庭农场主农业生产生态自觉性的作用机理。研究发现:非农职业经历对家庭农场主农业生产生态自觉性具有显著正向影响,具有高中及以上学历、高龄农场主非农职业经历对农业生产生态自觉性的影响效应较为显著;非农职业经历通过扩大土地流转规模和延长土地流转期限提高家庭农场主农业生产生态自觉性,且土地流转规模的中介效应影响更大。因此,政府应完善具备非农职业经历群体返乡创业激励机制,加大对家庭农场等新型经营主体农业生态生产政策支持力度,并适度推进土地流转规模扩张及土地流转期限长期化,推动农业生产可持续发展。

关键词：家庭农场主非农职业经历生态自觉性农业生产土地流转

Consensus on glycemic management for patients with coronary heart disease and type 2 diabetes

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Journal of Geriatric Cardiology 2024年第7期21卷 689-702页

作者： li-Nong JI Yun-Dai CHEN Jing liU Xiang-Hai ZHOU Cardiovascular Subcommittee of Chinese International Exchange and Promotion Association for Medical and Healthcare Peking University People's Hospital Chinese PLA General Hospital

The prevalence of patients with coronary heart disease(CHD)and diabetes mellitus is notably high,posing sig-nificant residual cardiovascular risks even after routine interventions such as antihypertensive,lipid-lowering,and antithrombot-ic *** studies have demonstrated that certain glucose-lowering medications confer cardiovascular benefits for pa-tients with type 2 ***,a survey indicates that cardiologists may not be fully acquainted with the optimal screen-ing timing,indicators,and diagnostic criteria for type 2 diabetes,and there is insufficient awareness and a low rate of prescrip-tion of novel glucose-lowering medications with proven cardiovascular efficacy,such as glucagon-like peptide-1 receptor agon-ists(GLP-1 RAs)and sodium-glucose co-transporter-2 inhibitors(SGLT-2i).In this context,based on domestic and international guidelines or consensus and the latest evidence-based evidence,this consensus aims to standardize the glycemic management for patients with acute coronary syndrome,chronic coronary syndrome,and perioperative management for percutaneous coronary *** highlights the key points of screening and diagnosis of type 2 diabetes,and the comprehensive management of cardiovascular risk in patients with *** consensus elaborates on the principles and algorithms of glycemic management for CHD patients,without involving acute complications of diabetes,clarifies the clinical practice of glucose-lowering medications with cardiovascular benefits,and promotes the standardized use of these medications in cardiovascular and other related spe-cialty ***,it addresses the glucose-lowering treatment to comprehensively reduce cardiovascular risks.

关键词： coronary patients routine

Gut microbiota and female health

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World Journal of Gastroenterology 2024年第12期30卷 1655-1662页

作者： Meng-Yao Wang li-Xuan Sang Si-Yu Sun Department of Gastroenterology Shengjing Hospital of China Medical UniversityShenyang 110022Liaoning ProvinceChina Department of Gastroenterology Endoscopic CenterEngineering Research Center of Ministry of Education for Minimally Invasive Gastrointestinal Endoscopic TechniquesShengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina

The gut microbiota is recognized as an endocrine organ with the capacity to influence distant organs and associated biological *** advan-cements underscore the critical role of gut microbial homeostasis in female health;with dysbiosis potentially leading to diseases among women such as polycystic ovarian syndrome,endometriosis,breast cancer,cervical cancer,and ovarian cancer *** this,there has been limited discussion on the underlying *** editorial explores the three potential mechanisms through which gut microbiota dysbiosis may impact the development of diseases among women,namely,the immune system,the gut microbiota-estrogen axis,and the metabolite *** focused on approaches for treating diseases in women by addressing gut microbiota imbalances through probiotics,prebiotics supple-mentation,and fecal microbiota transplantation(FMT).Future studies should focus on determining the molecular mechanisms underlying associations between dysbiosis of gut microbiota and female diseases to realize precision medicine,with FMT emerging as a promising intervention.

关键词： Gut microbiota Female health Estrogen Polycystic ovarian syndrome Endometriosis

From Acupoints to Mylohyoid: Revealing the Neural Circuitry Basis of Electroacupuncture for Dysphagia

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Neuroscience Bulletin 2024年第1期40卷 139-142页

作者： Xiaoli Da Xuhong Jiang lihong li Cenglin Xu Zhong Chen Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province School of Pharmaceutical ScienceZhejiang Chinese Medical UniversityHangzhou 310053China Department of Neurology the First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 310003China Department of Acupuncture the Second Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou 310000China

Acupuncturea representative and historical treatment in traditional Chinese medicine(TCM),has been used to cure diseases for Chinese people in the past *** the late 1990s,acupuncture has been further accepted *** World Health Organization(WHO)proposed Clinical Research Specification for acupuncture in 1995 and the US Food and Drug Administration(FDA)approved acupuncture as a complementary and alternative therapy for various kinds of diseases in 1996,with clinical advantages such as convenience and effectiveness[1].Cumulative evidence has proved that acupuncture could produce different degrees of efficacy for treating various kinds of diseases(such as neuropathic pain,migraine,Parkinson's disease et al.)and alleviate symptoms[2-4].However,unlike its evidence-based efficacies.

关键词： medicine(TCM) acupuncture Acupuncture

Zooplankton community response to eddy during dinoflagellate Noctiluca scintillans blooms off Pakistan,northern Arabian Sea

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Journal of Oceanology and limnology 2024年第5期42卷 1557-1570页

作者： Mahugnon Boris DEDO Xiping liAN Kaizhi li Chenhui XIANG Yehui TAN Key Laboratory of Tropical Marine Bioresources and Ecology Guangdong Provincial Key Laboratory of Applied Marine BiologySouth China Sea Institute of OceanologyChinese Academy of SciencesGuangzhou 510301China University of Chinese Academy of Sciences Beijing 100049China Innovation Academy of South China Sea Ecology and Environmental Engineering Chinese Academy of Sciences(ISEECAS)Guangzhou 510301China Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou 510301China

Eddies are major elements of ocean dynamics that affect ocean *** their effects on plankton distribution may help understand the dynamics of harmful phytoplankton *** studies on the effects of eddies in the northern Arabian Sea have primarily focused on the zooplankton community,and few have observed zooplankton dynamics during winter blooms of Noctiluca *** investigated zooplankton community structure and the related environmental variability during a *** bloom that was affected by an eddy in February *** sampling stations were deployed at eddy core and eddy edge distinguished in salinity,temperature,and *** show that *** bloomed at the eddy core with high-velocity currents induced by warm eddies that moved from eddy core to eddy *** a result,blooms significantly changed the zooplankton community ***-bloom stations had higher zooplankton diversity than bloom *** at non-bloom stations were dominated by either tunicates or copepods,such as Thalia democratica and Pleuromamma *** addition to the influence of *** blooms,the velocity of eddy currents was a crucial factor on the similarities in the zooplankton community composition between eddy edge and eddy ***,the lower abiotic factors in bloom area contribute to the structuring of the zooplankton community during *** blooms.

关键词： eddy zooplankton community Noctiluca scintillans northern Arabian Sea

Base editor-mediated large-scale screening of functional mutations in bacteria for industrial phenotypes

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Science China(life Sciences) 2024年第5期67卷 1051-1060页

作者： Yaomeng Yuan Xihao liao Shuang li Xin-Hui Xing Chong Zhang MOE Key Laboratory for Industrial Biocatalysis Institute of Biochemical EngineeringDepartment of Chemical EngineeringTsinghua UniversityBeijing 100084China Institute of Biopharmaceutical and Health Engineering Tsinghua Shenzhen International Graduate SchoolShenzhen 518055China Institute of Biomedical Health Technology and Engineering Shenzhen Bay LaboratoryShenzhen 440300China Center for Synthetic and Systems Biology Tsinghua UniversityBeijing 100084China

Base editing,the targeted introduction of point mutations into cellular DNA,holds promise for improving genome-scale functional genome screening to single-nucleotide *** efforts in prokaryotes,however,remain confined to loss-of-function screens using the premature stop codons-mediated gene inactivation library,which falls far short of fully releasing the potential of base ***,we developed a base editor-mediated functional single nucleotide variant screening pipeline in Escherichia *** constructed a library with 31,123 sgRNAs targeting 462 stress response-related genes in ***,and screened for adaptive mutations under isobutanol and furfural selective *** by the screening results,we successfully identified several known and novel functional *** pipeline might be expanded to the optimization of other phenotypes or the strain engineering in other microorganisms.

关键词： base editor high-throughput large-scale screening Escherichia coli functional mutation

Quantifying Inter-regional Trade Inequality of China's Cities Based on Environmental-economic Benefits in Virtual Built-up Land Flow

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China & World Economy 2024年第5期32卷 226-246页

作者： Pengfei Wang Hongbo li Zhenbin Huang College of Public Administration Huazhong Agricultural UniversityChina

The development of spatial interactions of land resources enhances virtual built-up land flow,which contributes to China's inter-regional trade *** is known about the degree of inequality among *** work seeks to estimate the degree of inter-regional trade inequality through environmental-economic *** combined a multiregional input-output model at the city level with a new classification to calculate the virtual built-up land flow among cities and analyzed its implications for the regional economy and carbon *** results indicate that developed regions were the main beneficiaries of inter-regional trade,as reflected in land-use ***'s economic hub has been progressively shifting southward,and the inter-regional trade inequality has continuously *** flow of virtual service industry land among developed regions rose,while underdeveloped regions remained suppliers of raw materials,further increasing inter-regional trade inequality.

关键词： built-up land carbon neutrality multiregional input-output model trade inequality

Androgens exert multifaceted functions in sex differences analyzed through single-cell transcriptome

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Science China life Sciences 2024年第11期67卷 2530-2531页

作者： Xinxin Tang Yinkun Fu Zhihui Zou Yue li Ming He Key Laboratory of Cell Differentiation and Apoptosis of Ministry of Education Shanghai Frontiers Science Center of Cellular Homeostasis and Human Diseases Department of Pathophysiology School of Medicine Shanghai Jiao Tong University Department of Pathology The Affiliated Hospital of Youjiang Medical University for Nationalities

Sex differences are ubiquitous in human development, aging and disease. For example, the overwhelming majority of non-reproductive system cancers are more common in males(Mauvais-Jarvis et al., 2020), while autoimmune diseases are more common in females. Hormones,especially androgens and oestrogens, contribute to sex-biased phenotypes(Khramtsova et al., 2019).

关键词： PROSTATE CASTRATION