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Fish-on-Chips:unveiling neural processing of chemicals in small animals through precise fluidic control

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Neural Regeneration Research 2024年第11期19卷 2351-2353页

作者： Samuel K.h.Sy ho Ko Division of Neurology Department of Medicine and TherapeuticsFaculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Li Ka Shing Institute of health Sciences Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Department of Electrical and Electronic Engineering Faculty of EngineeringThe University of Hong KongPok Fu LamHong Kong IslandHong Kong Special Administrative RegionChina Advanced Biomedical Instrumentation Center Hong Kong Science ParkPak Shek KokNew TerritoriesHong Kong Special Administrative RegionChina Margaret K.L.Cheung Research Center for Management of Parkinsonism Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Lau Tat-chuen Research Center of Brain Degenerative Diseases in Chinese Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina gerald Choa Neuroscience Institute The Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina

Precise chemical cue presentation alongside advanced brainwide imaging techniques is important to the study of chemosensory processing in ***,the dynamic nature of chemical-carrying media,such as water or air,poses a significant challenge for delivering highly-controlled chemical flow to an animal ***,contact-based cue manipulation and delivery easily shift the position of the animal subject,which is often undesirable for high-quality brain ***,more advanced interfacing tools that align with the diverse range of body part sizes of an animal,ranging from micrometer-scale neurons to meter-long limbs,are much *** is particularly crucial when dealing with dimensions that are beyond the reach of conventional experimental tools.

关键词： dealing precise sizes

A review of state-of-the-art processing operations in coal preparation

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International Journal of Mining Science and Technology 2015年第4期25卷 511-521页

作者： Noble Aaron Luttrell gerald h. Department of Mining Engineering West Virginia University Department of Mining & Minerals Engineering Virginia Tech

Coal preparation is an integral part of the coal commodity supply chain. This stage of post-mining, pre-utilization beneficiation uses low-cost separation technologies to remove unwanted mineral matter and moisture which hinder the value of the coal product. Coal preparation plants typically employ several parallel circuits of cleaning and dewatering operations, with each circuit designed to optimally treat a specific size range of coal. Recent innovations in coal preparation have increased the efficiency and capac- ity of individual unit operations while reinforcing the standard parallel cleaning approach. This article, which describes the historical influences and state-of-the-art design for the various coal preparation unit operations, is organized to distinguish between coarse/intermediate coal cleaning and fine/ultrafine coal cleaning. Size reduction, screening, classification, cleaning, dewatering, waste disposal unit operations are particularly highlighted, with a special focus on the LI.S. design philosophy. Notable differences between the U.S. and international operations are described as appropriate.

关键词： Coal preparation Coal supply chain Unit operations Particulate separations Tailings disposal

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全新世热带辐合带(ITCZ)的南移

海洋地质动态 2002年第9期18卷 33-35页

作者： gerald h haug 邓韫

Experimental studies and phase field modeling of microstructure evolution during solidification with electromagnetic stirring

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中国有色金属学会会刊：英文版 2010年第S3期20卷 774-780页

作者： P.gerald TENNYSON P.KUMAR h.LAKShMI G.PhANIKUMAR P.DUTTA Department of Metallurgical and Materials Engineering Indian Institute of Technology National Facility for Semisolid Forming Department of Mechanical EngineeringIndian Institute of Science

Thixocasting requires manufacturing of billets with non-dendritic *** alloy A356 billets were produced by rheocasting in a mould placed inside a linear electromagnetic *** heat treatment was used to produce a transition from rosette to globular *** current and the duration of stirring were explored as control *** induction heating of the billet during stirring was quantified using experimentally determined thermal *** effect of processing parameters on the dendrite fragmentation was *** computational modeling of the process was performed using phase-field modeling of alloy solidification in order to gain insight into the process of morphological changes of a solid during this process.A non-isothermal alloy solidification model was used for *** morphological evolution under such imposed thermal cycles was simulated and compared with experimentally determined *** scaling using the thermosolutal diffusion distances was used to overcome computational difficulties in quantitative comparison at system *** results were interpreted in the light of existing theories of microstructure refinement and globularisation.

关键词： electromagnetic stirring non-dendritic phase field modeling microstructure

Evaluation of acoustic radiation force impulse imaging for determination of liver stiffness using transient elastography as a reference

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World Journal of Gastroenterology 2012年第10期18卷 1077-1084页

作者： gerald Kircheis Abdurrahman Sagir Christoph Vogt Stephan vom Dahl Ralf Kubitz Dieter hussinger Department of Gastroenterology Hepatology and Infectious Diseases Heinrich-Heine-University Düsseldorf Moorenstrasse 5 Düsseldorf 40225 Germany Christoph Vogt St. Josef hospital Moers Asberger Str. 4 Moers 47441 Germany St. Franziskus hospital Schnsteinstraβe 63 Kln 50825 Germany

AIM: To evaluate cut-off values and performance of acoustic radiation force impulse imaging (ARFI) using transient elastography [FibroScan■ (FS)] as a reference. METhODS: Six hundred and six patients were enrolled in this *** patients underwent liver stiffness measurement with FS (FS-LS) and ARFI (with shear wave velocity quantification; ARFI-SWV) and the performance of ARFI in comparison to FS was determined. Sixtyeight patients underwent liver biopsy. RESULTS: Significantly higher success rates for the determination of liver stiffness were found using ARFI as compared to FS [604/606 (99.7%) vs 482/606 (79.5%); P h FS-LS (r = 0.920, P h the stage of fibrosis (1.09 ± 0.13 m/s for patients with no significant fibrosis (FS-LS h significant liver fibrosis (7.6 h liver cirrhosis (FS-LS > 13.0 kPa)). ARFI-SWV cut-off values were identified for no significant fibrosis (1.29 m/s; sensitivity 91.4% and specificity 92.6%) and for liver cirrhosis (1.60 m/s; sensitivity 92.3% and specificity 96.5%). The optimal cut-off value for predicting liver fibrosis (F ≥ 2) was 1.32 m/s (sensitivity 87.0% and specificity 80.0%) and for liver cirrhosis (F4) 1.62 m/s (sensitivity 100% and specificity 85.7%), for patients who underwent liver biopsy. An excellent inter-and intraobserver reproducibility was observed for ARFI-SWV determinations. CONCLUSION: An ARFI-SWV cut-off value of 1.29 m/s seems to be optimal for patients with no significant liver fibrosis and 1.60 m/s for patients with liver cirrhosis.

关键词： Acoustic radiation force impulse imaging Elastography Fibroscan Liver

Control of Rhyzopertha dominica in stored rough rice through a combination of diatomaceous earth and varietal resistance

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Insect Science 2008年第5期15卷 455-460页

作者： Yaowaluk Chanbang Frank h. Arthur gerald E. Wilde James E. Throne Chiang Mai University Chiang Mai Thailand USDA-ARS Grain Marketing and Production Research Center Manhattan KS USA Department of Entomology Kansas State University Manhattan KS USA

Adults ofRhyzopertha dominica （F.）, the lesser grain borer, were exposed on four varieties of rough rice with Dobie indices of susceptibility of 1.1 to 1.1 （low）, and four varieties with Dobie indices of susceptibility of 3.4 to 3.8 （high）. The varieties with low and high Dobie indices were classified as resistant and susceptible, respectively, to R. dominica. The purpose of the study was to evaluate control of R. dominica through the use of diatomaceous earth （DE） in combination with rice varieties that were either susceptible or resistant to R. dominica. The rice was treated with varying rates of the commercial DE Insecto, up to a maximum of 1 000 mg DE/kg of rice. Adult mortality at each application rate of DE was generally greater on three of four resistant varieties compared to three of four susceptible varieties. Progeny production from the parental generation exposed on the rice was also greater in 3 of the 4 resistant varieties compared to 3 of the 4 susceptible varieties at DE rates of 500 mg/kg or more. Progeny production in rice treated with a maximum rate of 1 000 mg/kg DE ranged from 7-44 adults on the resistant varieties compared to 75-155 adults on the susceptible varieties. At DE rates of 500, 750, and 1 000 mg/kg, the percentage of insect-damaged kernels （IDK） was also greater in 3/4 resistant varieties than in the susceptible varieties. Results show combining the use of DE with varietal resistance of rough rice to R. dominica could be used to limit populations of this insect in stored rice and help prevent economic damage.

关键词： diatomaceous earth DE host plant resistance integrated control rice

痴心不悔的人文主义者语言与艺术中的表现问题

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新美术 2024年第4期45卷 4-17页

作者： [英]E.h.贡布里希李本正(译) 不详天津美术学院

我的题目改自杰出钢琴家杰拉尔德·穆尔[gerald Moore]的一本书的书名,你们也许知道,他是世界上一些伟大歌唱家,诸如菲希尔·迪斯考[Fischer Dieskau]等人的伴奏者。穆尔撰写了一部脍炙人口的回忆录,名为《问心无愧的伴奏者》[The Unash... 详细信息

我的题目改自杰出钢琴家杰拉尔德·穆尔[gerald Moore]的一本书的书名,你们也许知道,他是世界上一些伟大歌唱家,诸如菲希尔·迪斯考[Fischer Dieskau]等人的伴奏者。穆尔撰写了一部脍炙人口的回忆录,名为《问心无愧的伴奏者》[The Unashamed Accompanist],他希望表明,与一些同行不同,他并不为自己在生活中扮演的角色感到难堪,他并不想当一名独奏者或者著名的音乐会钢琴家,也不以为歌唱家伴奏而感到羞愧。恐怕我作为一名人文主义者,还不如杰拉尔德·穆尔作为伴奏者一样出色,但是尽管我常常希望自己能更出色些,我却并不希望换一份别的工作。

关键词：伴奏者人文主义者穆尔杰拉尔德歌唱家钢琴家

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巴拿马隆起在大洋淡水平衡中的作用

海洋地质动态 2001年第8期17卷 19-22页

作者： gerald h haug 周立君

关于中美洲的上新世历史,最有趣的问题是中美洲航道最终关闭所起的作用以及其改变大洋循环和影响全球气候的可能性.航道关闭是引起地球气候史上北半球从显著温暖期变为冰盖生长期的主要因素.然而,关于上新世气候历史的几个基本问题仍然... 详细信息

关于中美洲的上新世历史,最有趣的问题是中美洲航道最终关闭所起的作用以及其改变大洋循环和影响全球气候的可能性.航道关闭是引起地球气候史上北半球从显著温暖期变为冰盖生长期的主要因素.然而,关于上新世气候历史的几个基本问题仍然存在争议.

关键词：巴拿马隆起淡水平衡中美洲上新世大洋循环全球气候生物地层学

Isolation by phage display and characterization of a single-chain antibody specific for O^6-methyldeoxyguanosine

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Chinese Science Bulletin 2001年第12期46卷 1024-1029页

作者： DAI heping ZhAO Rouhong haug Brenda Sean M.hemmingsen XIAO Wei Institute of hydrobiology Chinese Academy of SciencesWuhan 430072China Plant Biotechnology Institute National Research Council of CanadaSaskatoonSK S7N OW9Canada Department of Microbiology and Immunology University of SaskatchewanSaskatoonSK S7N 5E5Canada

New approaches of making single chain Fv antibodies against O6-methyl-2’ -deoxyguanosine (O6MdG) have been demonstrated by using the phage antibody display system. Using O6MdG as an antigen, 21 positive clones were identified by ELISA from this library, one of which, designated h3, specifically binds to O6MdG with high affinity. The h3 scFv antibody has an affinity constant (Kaff) of 5.94×1011(mol/L)-1. h3 scFv has been successfully used to detect O6MdG in DNA hydrolyses from yeast or E. coli cells treated with a DNA methylating agent. To our knowledge, this is the first report of the selection of a specific scFv against DNA adducts. The results demonstrate the potential applications of the phage display technology for the detection of DNA lesions caused by mutagens and carcinogens.

关键词： O6-methyl-2’ -deoxyguanosine, phage display antibody, single chain Fv DNA adducts.