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Detection of Arterial Occlusions Using Viscoelastic Wave Propagation

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Advances in Applied Mathematics and Mechanics 2009年第1期1卷 1-28页

作者： h.t.banks J.R.Samuels,Jr. Center for Research in Scientific Computation North Carolina State UniversityCampus Box 8212RaleighNC 27695-8212USA

We consider the problem of detecting cardiac artery occlusions using stenosis driven viscoelastic(VE)waves propagated through biotissue to body surface *** investigate possible statistical model formulations(ordinary least squares(OLS),generalized least squares(GLS))and post analysis techniques(residual plots)to ascertain uncertainty in estimates as well as validity of the statistical models as part of a methodology for stenosis detection using viscoelastic waves.

关键词： Inverse problems viscoelastic models wave propagation in biotissue statistical models

Dynamic Evasion-Interrogation Games with Uncertainty in the Context of Electromagetics

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Numerical Mathematics(theory,Methods and Applications) 2011年第3期4卷 359-378页

作者： h.t.banks Shuhua hu K.Ito Sarah Grove Muccio Center for Research in Scientific Computation North Carolina State UniversityRaleighNC 27695-8212USA.

We consider two player electromagnetic evasion-pursuit games where each player must incorporate significant uncertainty into their design strategies to disguise their intension and confuse their *** this paper,the evader is allowed to make dynamic changes to his strategies in response to the dynamic input with uncertainty from the *** problem is formulated in two different ways;one is based on the evolution of the probability density function of the intensity of reflected signal and leads to a controlled forward Kolmogorov or Fokker-Planck *** other formulation is based on the evolution of expected value of the intensity of reflected signal and leads to controlled backward Kolmogorov *** addition,a number of numerical results are presented to illustrate the usefulness of the proposed approach in exploring problems of control in a general dynamic game setting.

关键词： Electromagnetic evasion-pursuit uncertainty feedback control computational methods Kolmogorov and Fokker-Planck equations.

Determination of Interrogating Frequencies to Maximize Electromagnetic Backscatter from Objects with Material Coatings

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Communications in Computational Physics 2006年第2期1卷 362-382页

作者： h.t.banks K.Ito J.toivanen Center for Research in Scientific Computation Box 8205North Carolina State UniversityRaleighNC 27695-8205USA

the electromagnetic backscattering of a crosscut of a cruise missile coated by a thin homogeneous layer made of radar absorbent material is modeled using a finite element *** on the radar cross section and a reflection coefficient,optimization problems are formulated for evaders and interrogators leading to optimal material parameters for the coating and optimal monostatic radar operating frequencies,*** coating materials are constructed for several radar *** only dielectric permittivity gives a narrow frequency range of high absorption while also tuning magnetic permeability widens it *** the coating layers considered do not provide substantial reduction of backscattering in the entire frequency range from 0.2 to 1.6 *** experiments also demonstrate that the reflection coefficient based on a simple planar geometry can predict well the strength of radar cross section in the sector of interest with a substantially reduced computational burden.

关键词： Radar cross section radar absorbent material optimization finite element model

Viscoelastic Models for Passive Arterial Wall Dynamics

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Advances in Applied Mathematics and Mechanics 2009年第2期1卷 151-165页

作者： D.Valdez-Jasso h.t.banks M.A.haider D.Bia Y.Zocalo R.L.Armentano M.S.Olufsen Department of Mathematics and Center for Research in Scientific Computation NC State UniversityCampus Box 8205RaleighNC 27695 Departmento de Fisiologia Facultad de MedicinaUniversidad de La RepublicaGeneral Flores 2125PC:11800MontevideoUruguay Facultad de Ingenieria y Ciencias Exactas y Naturales Universidad FavaloroAvda.Belgrano 1723Capital FederalBuenos AiresArgentina

this paper compares two models predicting elastic and viscoelastic properties of large *** compared include a Kelvin(standard linear)model and an extended 2-term exponential linear viscoelastic *** were validated against in-vitro data from the ovine thoracic descending aorta and the carotid *** of blood pressure data were used as an input to predict vessel cross-sectional *** properties were predicted by estimating a set of model parameters that minimize the difference between computed and measured values of the cross-sectional *** model comparison was carried out using generalized analysis of variance type statistical *** the thoracic descending aorta,results suggest that the extended 2-term exponential model does not improve the ability to predict the observed cross-sectional area data,while for the carotid artery the extended model does statistically provide an improved fit to the *** is in agreement with the fact that the aorta displays more complex nonlinear viscoelastic dynamics,while the stiffer carotid artery mainly displays simpler linear viscoelastic dynamics.

关键词： Arterial wall modeling dynamic viscoelastic models inverse problems statistical analysis for model comparison

RARRES2's impact on lipid metabolism in triplenegative breast cancer:a pathway to brain metastasis

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Military Medical Research 2024年第2期11卷 311-312页

作者： Quazi t.h.Shubhra Institute of Chemistry University of Silesia in Katowice41‑500 ChorzowPoland Department of Neurosurgery Renmin Hospital of Wuhan UniversityWuhan 430060China

Breast cancer brain metastasis(BCBrM)is a crucial and hard area of research which guarantees an urgent need to understand the underlying molecular mechanisms.A recent study by Li et al.[1]published in Military Medical Research investigated the role of retinoic acid receptor responder 2(RARRES2)in regulating lipid metabolism in BCBrM,highlighting the clinical relevance of alterations in lipid metabolites,such as phosphatidylcholine(PC)and triacylglycerols(tAGs),by RARRES2 through the modulation of phosphatase and tensin homologue(PtEN)-mammalian target of rapamycin(mtOR)-sterol regulatory element-binding protein 1(SREBP1)signaling *** commentary aims to elaborate on the key findings and their relevance to the field.

关键词： Retinoic acid receptor responder 2(RARRES2) Lipid metabolism Cancer PtEN-mtOR-SREBP1 signaling Metabolic reprogramming Brain metastasis

Pre-activated macrophage membrane-encased aggregationinduced emission featuring nanoparticles:a novel possibility for tuberculosis treatment

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Signal transduction and targeted therapy 2024年第7期9卷 2848-2850页

作者： Qiang Cai Yihao tian Quazi t.h.Shubhra Department of Neurosurgery Renmin Hospital of Wuhan UniversityWuhanChina Department of human Anatomy and histology and Embryology School of Basic Medical SciencesWuhan UniversityWuhanChina Institute of Chemistry University of Silesia in KatowiceSzkolna 9KatowicePoland

In a recent study published in Nature Nanotechnology,Li et *** the synthesis of a novel photosensitizer with unique aggregation-induced emission(AIE)characteristics.1 they microencapsulated this photosensitizer inside engineered nanoparticles(NPs)coated with pre-activated macrophage cell membranes(CMs),an innovative approach marking a significant leap in nanomedicine by offering a pathway to potent tuberculosis(tB)treatments that bypass antibiotic resistance with unparalleled precision.

关键词： tuberculosis macrophage aggregation

Superplasticity of fine-grained Mg-10Li alloy prepared by severe plastic deformation and understanding its deformation mechanisms

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Journal of Magnesium and Alloys 2024年第1期12卷 316-331页

作者： h.t.Jeong S.W.Lee W.J.Kim Department of Materials Science and Engineering Hongik UniversityMapo-guSangsu-dong 72-1Seoul 121-791Republic of Korea

the superplastic behavior and associated deformation mechanisms of a fine-grained Mg-10.1 Li-0.8Al-0.6Zn alloy(LAZ1011)with a grain size of 3.2μm,primarily composed of the BCCβphase and a small amount of the hCPαphase,were examined in a temperature range of 473 K to 623 *** microstructural refinement of this alloy was achieved by employing high-ratio differential speed *** best superplasticity was achieved at 523 K and at strain rates of 10^(-4)-5×10^(-4)s^(-1),where tensile elongations of 550±600%were *** the heating and holding stage of the tensile samples prior to tensile loading,a significant increase in grain size was observed at temperatures above 573 ***,it was important to consider this effect when analyzing and understanding the superplastic deformation behavior and *** the investigated strain rate range,the superplastic flow at low strain rates was governed by lattice diffusion-controlled grain boundary sliding,while at high strain rates,lattice diffusion-controlled dislocation climb creep was the rate-controlling deformation *** was concluded that solute drag creep is unlikely to *** the late stages of deformation at 523 K,it was observed that grain boundary sliding led to the agglomeration of theαphase,resulting in significant strain *** mechanism maps were constructed forβ-Mg-Li alloys in the form of 2D and 3D formats as a function of strain rate,stress,temperature,and grain size,using the constitutive equations for various deformation mechanisms derived based on the data of the current tests.

关键词： Magnesium-lithium alloy Superplasticity Severe plastic deformation Grain size Grain growth

Correlation of work function and stacking fault energy through Kelvin probe force microscopy and nanohardness in diluteα-magnesium

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Journal of Magnesium and Alloys 2024年第1期12卷 237-250页

作者： Yigit türe Ali Arslan Kaya hüseyin Aydin Jiang Peng Servet turan Eskisehir technical University Porsuk Vocational SchoolElectronics and Automation DepartmentProgram of MechatronicsEskisehirTurkey Mugla Sitki Kocman University Engineering FacultyMetallurgy and Materials Engineering DepartmentMuglaTurkey hüseying Aydın TUBITAK MRCTurkey Jiang Peng Chongqing UniversityChina Eskisehir technical University Engineering FacultyMaterials Science and Engineering DepartmentEskisehirTurkey

Electronic interactions of the Group 2A elements with magnesium have been studied through the dilute solid solutions in binary Mg-Ca,Mg-Sr and Mg-Ba *** investigation incorporated the difference in the‘Work Function'(ΔWF)measured via Kelvin Probe Force Microscopy(KPFM),as a property directly affected by interatomic bond types,*** electronic structure,nanoindentation measurements,and Stacking Fault Energy values reported in the *** was shown that the nano-hardness of the solid-solutionα-Mg phase changed in the order of Mg-Ca>Mg-Sr>***,it was shown,by also considering the nano-hardness levels,that SFE of a solid-solution is closely correlated with its‘Work Function'***-hardness measurements on the eutectics andΔWF difference between eutectic phases enabled an assessment of the relative bond strength and the pertinent electronic structures of the eutectics in the three *** withΔWF and at least qualitative verification of those computed SFE values with some experimental measurement techniques were considered important as those computational methods are based on zero Kelvin degree,relatively simple atomic models and a number of *** asserted by this investigation,if the results of measurement techniques can be qualitatively correlated with those of the computational methods,it can be possible to evaluate the electronic structures in alloys,starting from binary systems,going to ternary and then multi-elemental *** investigation has shown that such a qualitative correlation is *** all,the SFE values are not treated as absolute values but rather become essential in comparative investigations when assessing the influences of alloying elements at a fundamental level,that is,free electron density *** study indicated that the principles of‘electronic metallurgy'in developing multi-elemental alloy systems can be followed via practical experimental methods,i.e.ΔWF measurements using KPF

关键词： Mg alloys Dilute alloys Work function Stacking fault energy Kelvin probe force microscopy Short range order Miedema Nanoindentation Eutectics

Efficient guiding and focusing of intense laser pulse using periodic thin slits

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Matter and Radiation at Extremes 2024年第4期9卷 29-39页

作者： L.Xu t.W.huang K.Jiang C.N.Wu h.Peng P.C.hen R.Li h.B.Zhuo C.t.Zhou Shenzhen Key Laboratory of Ultraintense Laser and Advanced Material technology Center for Intense Laser ApplicationTechnologyand College of Engineering PhysicsShenzhen Technology UniversityShenzhen 518118People’s Republic of China

Slits have been widely used in laser-plasma interactions as plasma optical components for generating high-harmonic light and controlling laser-driven particle ***,we propose and demonstrate that periodic thin slits can be regarded as a new breed of optical elements for efficient focusing and guiding of intense laser *** fundamental physics of intense laser interaction with thin slits is studied,and it is revealed that relativistic effects can lead to enhanced laser focusing far beyond the pure diffractive focusing *** addition,the interaction of an intense laser pulse with periodic thin slits makes it feasible to achieve multifold enhancement in both laser intensity and energy transfer efficiency compared with conventional *** results provide a novel method for manipulating ultra-intense laser pulses and should be of interest for many laser-based applications.

关键词： laser pulse intense