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Semicrystalline Unfused Polymer Donors with Backbone halogenation toward Cost-Effective Organic Solar Cells

Chinese Journal of Chemistry 2024年第7期42卷 752-759页

作者： Yuxin Kong Shijie Ju hongmei Qin Min hun Jee Simeng Xia Jiaqi Ren chao Gao Jianyu Yuan Wenyan Su han Young Woo Yuxiang Li School of Materials Science and Engineering Xi'an University of Science and TechnologyXianShaanxi 710054China Department of Chemistry Korea UniversitySeoul 02841Republic of Korea Xi'an Key Laboratory of Liquid Crystal and Organic Photovoltaic Materials State Key Laboratory of Fluorine&Nitrogen ChemicalsXi'an Modern Chemistry Research InstituteXi'anShaanxi 710065China Jiangsu Key Laboratory for Carbon-Based Functional Materials&Devices Institute of Functional Nano&Soft Materials(FUNSOM)Soochow University199 Ren'ai RoadSuzhouJiangsu 215123China

Developing novel unfused building blocks with simple synthesis and low cost is essential to advance and enrich cost-effective poly-mer donors;however,it remains a challenge due to the lack of efficient molecular ***,a class of low-cost and fully unfused polymer donors with precisely regulated backbone planarity via halogenation was designed and synthesized,namely PDTBTBz-2h,PDTBTBz-2F,and *** polymer donors possess a four-step synthesis route with over 80%yield from cheap raw chemicals comparable to existing low-cost polymer donors,such as *** from the planar backbone via in-corporating the F…S non-covalent interactions,PDTBTBz-2F exhibits more robust J-type aggregation in solution and a long-ranged molecular stacking in film relative to PDTBTBz-2h and ***,the systematical study of PDTBTBz-based organic so-lar cells(OSCs)reveals the close relationship between optimized molecular self-assembly and charge separation/transport regarding backbone halogenation when paired with the non-fullerene acceptor(Y6-BO-4F).As a result,the photovoltaic devices based on semicrystalline PDTBTBz-2F achieved a promising power conversion efficiency(PCE)of 12.37%.Our work highlighted the influence of backbone halogenation on the molecular self-assembly properties and a potential unfused backbone motif for further developing cost-effective OSCs.

关键词： Low-cost Polymer donors Backbone halogenation Molecular self-assembly Organic solar cells

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Identification of anti-gastric cancer effects and molecular mechanisms of resveratrol: From network pharmacology and bioinformatics to experimental validation

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 493-513页

作者： Ying-Qian Ma Ming Zhang Zhen-hua Sun hong-Yue Tang Ying Wang Jiang-Xue Liu Zhan-Xue Zhang chao Wang Department of Oncology Hebei General HospitalShijiazhuang 050051Hebei ProvinceChina School of Graduate Studies Hebei Medical UniversityShijiazhuang 050017Hebei ProvinceChina Clinical Medical Research Center Hebei General HospitalShijiazhuang 050051Hebei ProvinceChina Department of Gastrointestinal Surgery Second Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina

BACKGROUND Gastric cancer(GC)is one of the most aggressive malignancies with limited therapeutic options and a poor ***,a non-flavonoid poly-phenolic compound found in a variety of Chinese medicinal materials,has shown excellent anti-GC ***,its exact mechanisms of action in GC have not been *** To identify the effects of resveratrol on GC progression and explore the related molecular *** Action targets of resveratrol and GC-related targets were screened from public *** overlapping targets between the two were confirmed using a Venn diagram,and a“Resveratrol-Target-GC”network was constructed using Cyto-scape software version *** protein-protein interaction(PPI)network was constructed using STRING database and core targets were identified by PPI network *** Database for Annotation,Visualization and Integrated A total of 378 resveratrol action targets and 2154 GC disease targets were obtained from public databases,and 181 intersection targets between the two were screened by Venn *** top 20 core targets were identified by PPI network analysis of the overlapping *** function analysis mainly involved protein binding,identical protein binding,cytoplasm,nucleus,negative regulation of apoptotic process and response to xenobiotic *** enrichment analysis suggested that the involved signaling pathways mainly included PI3K-AKT signaling pathway,MAPK signaling pathway,IL-17 signaling pathway,TNF signaling pathway,ErbB signaling pathway,*** murine osteosarcoma viral oncogene homolog(FOS)and matrix metallopeptidase 9(MMP9)were selected by differential expression analysis,and they were closely associated with immune *** docking results showed that resveratrol docked well with these two *** treatment arrested the cell cycle at the S phase,induced apoptosis,and weakened viability,migration and invasion in a dose-dependent ***,re

关键词： Resveratrol Gastric cancer Network pharmacology Bioinformatics Molecular docking

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Expanding the targeting scope of CRISPR/Cas9-mediated genome editing by Cas9 variants in Brassica

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aBIOTECh 2024年第2期5卷 202-208页

作者： Wenjing Li Xuan Li Chunyang Wang Guanzhong huo Xinru Zhang Jintai Yu Xiaoxiao Yu Jing Li chao Zhang Jianjun Zhao Yan Li Jun Li State Key Laboratory of North China Crop Improvement and Regulation College of Life SciencesHebei Agricultural UniversityBaoding 071001China hebei Key Laboratory of Plant Physiology and Molecular Pathology Hebei Agricultural UniversityBaoding 071001China Key Laboratory of Vegetable Germplasm Innovation and Utilization of hebei Collaborative Innovation Center of Vegetable Industry in HebeiCollege of HorticultureHebei Agricultural UniversityBaoding 071001China College of Modern Science and Technology Hebei Agricultural UniversityBaoding 071001China

CRISPR/Cas9,presently the most widely used genome editing technology,has provided great potential for functional studies and plant ***,the strict requirement for a protospacer adjacent motif(PAM)has hindered the application of the CRISPR/Cas9 system because the number of targetable genomic sites is ***,the engineered variants Cas9-NG,SpG,and SpRY,which recognize non-canonical PAMs,have been successfully tested in plants(mainly in rice,a monocot).In this study,we evaluated the targeted mutagenesis capabilities of these Cas9 variants in two important Brassica vegetables,Chinese cabbage(Brassica rapa ***)and cabbage(Brassica oleracea ***).Both Cas9-NG and SpG induced efficient mutagenesis at NGN PAMs,while SpG outperformed Cas9-NG at NGC and NGT *** achieved efficient editing at almost all PAMs(NRN[NYN),albeit with some self-targeting activity at transfer(T)-DNA *** SpRY-induced mutants were detected in cabbage plants in a PAM-less ***,an adenine base editor was developed using SpRY and TadA8e deaminase that induced A-to-G conversions within target sites using non-canonical ***,the toolboxes developed here induced successful genome editing in Chinese cabbage and *** work further expands the targeting scope of genome editing and paves the way for future basic research and genetic improvement in Brassica.

关键词： Brassica Cas9 variants CRISPR Genome editing Non-canonical PAM

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Musielak–Orlicz–Lorentz hardy Spaces: Maximal Function, Finite Atomic, and Littlewood–Paley Characterizations with Applications to Dual Spaces and Summability of Fourier Transforms

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Acta Mathematica Sinica,English Series 2024年

作者： hong chao JIA Der-Chen ChANG Ferenc WEISZ Da Chun YANG Wen YUAN Department of Numerical Analysis E?tv?s L.University Laboratory of Mathematics and Complex Systems (Ministry of Education of China) School of Mathematical Sciences Beijing Normal University Department of Mathematics and Statistics Georgetown University Washington Institute of Business Administration College of Management Fu Jen Catholic University

Let q ∈(0, ∞] and φ be a Musielak–Orlicz function with uniformly lower type pφ-∈(0, ∞) and uniformly upper type pφ+∈(0, ∞). In this article, the authors establish various realvariable characterizations of the Musielak–Orlicz–Lorentz hardy space hφ,q(Rn), respectively, in terms of various maximal functions, finite atoms, and various Littlewood–Paley functions. As applications, the authors obtain the dual space of hφ,q(Rn) and the summability of Fourier transforms from hφ,q(Rn)to the Musielak–Orlicz–Lorentz space Lφ,q(Rn) when q ∈(0, ∞) or from the Musielak–Orlicz hardy space hφ(Rn) to Lφ,∞(Rn) in the critical case. These results are new when q ∈(0, ∞) and also essentially improve the existing corresponding results(if any) in the case q = ∞ via removing the original assumption that φ is concave. To overcome the essential obstacles caused by both that φmay not be concave and that the boundedness of the powered hardy–Littlewood maximal operator on associated spaces of Musielak–Orlicz spaces is still unknown, the authors make full use of the obtained atomic characterization of hφ,q(Rn), the corresponding results related to weighted Lebesgue spaces,and the subtle relation between Musielak–Orlicz spaces and weighted Lebesgue spaces.

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STCF conceptual design report (Volume 1): Physics & detector

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Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.C.Ai L.P.An R.Aliberti Q.An X.Z.Bai Y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko Z.h.Bu F.M.Cai h.Cai J.J.Cao Q.h.Cao X.Cao Z.Cao Q.Chang K.T.chao D.Y.Chen h.Chen h.X.Chen J.F.Chen K.Chen L.L.Chen P.Chen S.L.Chen S.M.Chen S.Chen S.P.Chen W.Chen X.Chen X.F.Chen X.R.Chen Y.Chen Y.Q.Chen h.Y.Cheng J.Cheng S.Cheng T.G.Cheng J.P.Dai L.Y.Dai X.C.Dai D.Dedovich A.Denig I.Denisenko J.M.Dias D.Z.Ding L.Y.Dong W.h.Dong V.Druzhinin D.S.Du Y.J.Du Z.G.Du L.M.Duan D.Epifanov Y.L.Fan S.S.Fang Z.J.Fang G.Fedotovich C.Q.Feng X.Feng Y.T.Feng J.L.Fu J.Gao Y.N.Gao P.S.Ge C.Q.Geng L.S.Geng A.Gilman L.Gong T.Gong B.Gou W.Gradl J.L.Gu A.Guevara L.C.Gui A.Q.Guo F.K.Guo J.C.Guo J.Guo Y.P.Guo Z.h.Guo A.Guskov K.L.han L.han M.han X.Q.hao J.B.he S.Q.he X.G.he Y.L.he Z.B.he Z.X.heng B.L.hou T.J.hou Y.R.hou C.Y.hu h.M.hu K.hu R.J.hu W.h.hu X.h.hu Y.C.hu J.hua G.S.huang J.S.huang M.huang Q.Y.huang W.Q.huang X.T.huang X.J.huang Y.B.huang Y.S.huang N.hüsken V.Ivanov Q.P.Ji J.J.Jia S.Jia Z.K.Jia h.B.Jiang J.Jiang S.Z.Jiang J.B.Jiao Z.Jiao h.J.Jing X.L.Kang X.S.Kang B.C.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.Lei E.Levichev C.h.Li C.Li D.Y.Li F.Li G.Li G.Li h.B.Li h.Li h.N.Li h.J.Li h.L.Li J.M.Li J.Li L.Li L.Li L.Y.Li N.Li P.R.Li R.h.Li S.Li T.Li W.J.Li X.Li X.h.Li X.Q.Li X.h.Li Y.Li Y.Y.Li Z.J.Li h.Liang J.h.Liang Y.T.Liang G.R.Liao L.Z.Liao Y.Liao C.X.Lin D.X.Lin X.S.Lin B.J.Liu C.W.Liu D.Liu F.Liu G.M.Liu h.B.Liu J.Liu J.J.Liu J.B.Liu K.Liu K.Y.Liu K.Liu L.Liu Q.Liu S.B.Liu T.Liu X.Liu Y.W.Liu Y.Liu Y.L.Liu Z.Q.Liu Z.Y.Liu Z.W.Liu I.Logashenko Y.Long C.G.Lu J.X.Lu N.Lu Q.F.Lü Y.Lu Y.Lu Z.Lu P.Lukin F.J.Luo T.Luo X.F.Luo Y.h.Luo h.J.Lyu X.R.Lyu J.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas S.Malde D.Matvienko Z.X.Meng R.Mitchell A.Nefediev Y.Nefedov S.L.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei h.P.Peng L.Peng X.Y.Peng X.J.Peng K.Peters S.Pivovarov E.Pyata B.B.Qi Y.Q.Qi W.B.Qian Y.Qian C.F.Qiao J.J.Qin J.J.Qin L.Q.Qin X.S.Qin T.L.Qiu J.Rademacker C.F.Redmer h.Y.Sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker Institute of Nuclear Physics Novosibirsk 630090Russia CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central China Normal University Wuhan 430079China Central South University Changsha 410083China China University of Geosciences Wuhan 430074China China University of Mining and Technology Xuzhou 221116China École Polytechnique Fédérale de Lausanne(EPFL) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China hangzhou Institute for Advanced Study UCASHangzhou 310024China hebei Normal University Shijiazhuang 050024China hebei University Baoding 071002China hefei University of Technology Hefei 230601China helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany henan Normal University Xinxiang 453007China henan University Kaifeng 475004China high Energy Physics Center Chung-Ang UniversitySeoul 06974Korea higher School of Economy 11 Pokrovsky Bulvar Moscow 109028Russia huangshan University Huangshan 245000China hubei University of Automotive Technology Shiyan 442002China hunan Normal University Changsha 410081China hunan University of Science and Technology Xiangtan 411201China hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of Advanced Science Facilities Shenzhen 518107China Institute of high Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China Jilin University Changch

The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or *** STCF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** STCF project in China is under development with an extensive R&D *** document presents the physics opportunities at the STCF,describes conceptual designs of the STCF detector system,and discusses future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity STCF detector conceptual design

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Construction of MTX-CS-TMP-NPs Nano-drug Delivery System and its Observation on Telomerase Activity of Cervical Cancer hela Cells

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Chinese Journal of Biomedical Engineering(English Edition) 2024年第1期33卷 27-32,39页

作者： YAN Xiao-shuai LUO chao YANG Fang The Fifth hospital of Xianmen Xiamen Fujian 361101China

Objective:To construct methotrexate(MTX)-chitosan(CS)-chuanxiongmuizine(TMP)nano-delivery system MTX-CS-TMP-NPs,and to investigate its effect on the telomerase activity of cervical cancer hela ***:MTX-CS and MTX-CS-TMP-NPs were prepared by amide reaction and ionic gel method,and the encapsulation rate and drug loading rate were *** method and TRAP method were used to detect hela cells and telomerase activity,and to compare the difference of telomerase activity of MTX,MTX-CS,and MTX-CS-TMP-NPs on cervical cancer hela ***:In this study,the total amount of TMP was 150μg,of which the amount of free TMP was(26.46±1.72)μg,the encapsulation rate of TMP was(82.36±0.01)%,and the drug loading was(17.62±0.23)*** activity of hela cells increased with the extension of time,and the OD value of hela cell activity(1.24±0.05)was lower than that of the other three groups at 72 h of treatment,and the difference was statistically significant(Phe telomerase activity of he La cells in the MTX-CS-TMP-NPs solution treatment group was(0.23±0.12)%lower than that of the other three groups,with statistically significant difference(Phe activity and telomerase activity of cervical cancer hela cells,showing its potential anti-cervical cancer effect.

关键词： cervical cancer(CC) Docetaxel MTX telomerase nano-drug delivery system cell cycle

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Polysaccharide of Alocasia cucullata Exerts Antitumor Effect by Regulating Bcl-2, Caspase-3 and ERK1/2 Expressions during Long-Time Administration

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Chinese Journal of Integrative Medicine 2024年第1期30卷 52-61页

作者： ZhOU Qi-chun XIAO Shi-lin LIN Ru-kun LI Chan ChEN Zhi-jie ChEN Yi-fei LUO chao-hua MO Zhi-xian LIN Ying-bo School of Traditional Chinese Medicine Southern Medical UniversityGuangzhou(510515)China Clinical and Basic Research Team of TCM Prevention and Treatment of Non-Small Cell Lung Cancer the Second Clinical College of Guangzhou University of Chinese MedicineGuangzhou(510120)China Department of Chinese Medicine Zhujiang Hospital Affiliated to Southern Medical UniversityGuangzhou(510282)China Department of Pharmacy Jiangmen Central HospitalJiangmen(529000)China

Objective: To study the in vitro and in vivo antitumor effects of the polysaccharide of Alocasia cucullata(PAC) and the underlying mechanism. Methods: B16F10 and 4T1 cells were cultured with PAC of 40 μg/m L, and PAC was withdrawn after 40 days of administration. The cell viability was detected by cell counting kit-8. The expression of Bcl-2 and Caspase-3 proteins were detected by Western blot and the expressions of ERK1/2 mRNA were detected by quantitative real-time polymerase chain reaction(qRT-PCR). A mouse melanoma model was established to study the effect of PAC during long-time administration. Mice were divided into 3 treatment groups: control group treated with normal saline, positive control group(LNT group) treated with lentinan at 100 mg/(kg·d), and PAC group treated with PAC at 120 mg/(kg·d). The pathological changes of tumor tissues were observed by hematoxylin-eosin staining. The cell apoptosis of tumor tissues was detected by TUNEL staining. Bcl-2 and Caspase-3 protein expressions were detected by immunohistochemistry, and the expressions of ERK1/2, JNK1 and p38 mRNA were detected by qRT-PCR. Results: In vitro, no strong inhibitory effects of PAC were found in various tumor cells after 48 or 72 h of administration. Interestingly however, after 40 days of cultivation under PAC, an inhibitory effect on B16F10 cells was found. Correspondingly, the long-time administration of PAC led to downregulation of Bcl-2 protein(P he above results were verified by in vivo experiments. In addition, viability of B16F10 cells under long-time administration culture in vitro decreased after drug withdrawal, and similar results were also observed in 4T1 cells. Conclusions: Long-time administration of PAC can significantly inhibit viability and promote apoptosis of tumor cells, and had obvious antitumor effect in tumor-bearing mice.

关键词： polysaccharide of Alocasia cucullata tumor cells Bcl-2 Caspase-3 ERK1/2 Chinese medicine

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Predictive performance of the variation rate of the driving pressure on the outcome of invasive mechanical ventilation in patients with acute respiratory distress syndrome

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Chinese Journal of Traumatology 2024年第2期27卷 107-113页

作者： hui-Dan Jing Jun-Ying Tian Wei Li Bing-Ling he hong-chao Li Fu-Xia Jian Cui Shang Feng Shen Department of Intensive Care Unit The Affiliated Hospital of Guizhou Medical UniversityGuiyang 550004China Department of Intensive Care Unit Army Medical Center of PLAChongqing400042China College of Foreign Languges Chongqing Medical UniversityChongqing400016China

Purpose:To assess the value of the driving pressure variation rate(ΔP%)in predicting the outcome of weaning from invasive mechanical ventilation in patients with acute respiratory distress ***:In this case-control study,a total of 35 patients with moderate-severe acute respiratory distress syndrome were admitted to the intensive care unit between January 2022 and December 2022 and received invasive mechanical ventilation for at least 48 h were *** were divided into successful weaning group and failed weaning group depending on whether they could be removed from ventilator support within 14 *** measures including driving pressure,PaO2:FiO2,and positive end-expiratory pressure,*** assessed every 24 h from day 0 to day 14 until successful weaning was *** measurement data of non-normal distribution were presented as median(Q1,Q3),and the differences between groups were compared by Wilcoxon rank sum *** categorical data use the Chi-square test or Fisher's exact test to *** predictive value ofΔP%in predicting the outcome of weaning from the ventilator was analyzed using receiver operating characteristic ***:Of the total 35 patients included in the study,17 were successful vs.18 failed in weaning from a ventilator after 14 days of mechanical *** cut-off values of the medianΔP%measured by Operator 1 *** 2 in the first 4 days were≥4.17%and 4.55%,respectively(ph the area under curve of 0.804(sensitivity of 88.2%,specificity of 64.7%)and 0.770(sensitivity of 88.2%,specificity of 64.7%),*** was a significant difference in mechanical ventilation duration between the successful weaning group and the failure weaning group(8(6,13)vs.12(7.5,17.3),p=0.043).The incidence of ventilator-associated pneumonia in the successful weaning group was significantly lower than in the failed weaning group(0.2‰vs.2.3‰,p=0.001).There was a significant difference noted between these

关键词： Driving pressure Driving pressure variation rate Acute respiratory distress syndrome Mechanical ventilation

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Efficient and selective h_(2)O_(2)production through uranyl-assisted photocatalytic oxygen reduction reaction process in a uranium-organic framework

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Science China Chemistry 2024年第7期67卷 2274-2281页

作者： Jianxin Song chao Liang Baoyu Li Xuemin Wang Min Lei Lisha Jiang Zhenyu Li Yugang Zhang Jian Xie Zuju Ma Xing Dai Yanlong Wang Shuao Wang Wei Liu School of Environmental and Materials Engineering Yantai UniversityYantai 264005China State Key Laboratory of Radiation Medicine and Protection School for Radiological and Interdisciplinary Sciences(RAD-X)and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education InstitutionsSoochow UniversitySuzhou 215123China School of Life and Environmental Sciences Shaoxing UniversityShaoxing 312000China School of Nuclear Science and Technology Xi’an Jiaotong UniversityXi’an 710049China

harnessing solar energy by photocatalytically converting oxygen and water into high-value-added h_(2)O_(2)is a promising way of alleviating both environmental and energy *** is worth noting that suppressing detrimental side reactions,such as the generation of·O_(2)^(-),is a critical approach to enhancing h_(2)O_(2)***,a 2-fold interpenetrating 3D uranium-organic framework(YTU-W-1)was developed and introduced for photocatalytic h_(2)O_(2)*** material demonstrates a different photocatalytic mechanism when employing uranyl as an initiator,as compared with the conventional semiconductor photocatalytic pathway involving photo-generated charge *** from the strong hydrogen abstraction effect of the U≡O·and the direct one-step oxygen reduction pathway,YTU-W-1 exhibits enhanced photocatalytic performance for h_(2)O_(2)production with yield efficiency of 221μmol h^(-1)g^(-1).Furthermore,YTU-W-1 displays a high h_(2)O_(2)selectivity of 68%,confirmed by rotating ring-disk electrode(RRDE)*** were used to elucidate the critical role of uranyl in the photocatalytic oxygen reduction reaction for h_(2)O_(2)*** research introduces an innovative approach to photo-driven h_(2)O_(2)production,underscoring the potential for heterogeneous catalysts to engage in photocatalytic reactions independently of photogenerated charge carriers.

关键词： uranyl metal-organic frameworks oxygen reduction reaction photocatalytic h_(2)O_(2)synthesis

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“半城半牧”:牧区两栖式城镇化发展特点与成因剖析——基于青海省h县的调查

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青海社会科学 2024年第2期 61-67页

作者：刘超四川大学公共管理学院

实现以人为核心的新型城镇化是中国式现代化的必由之路和重要标志,也是推动民族地区经济社会文化发展的驱动力。青海省h县地方政府将移民工程与城镇化发展战略相结合,将牧区人口向小城镇集中,形成了“两栖式”新型城镇化,表现为城镇与... 详细信息

实现以人为核心的新型城镇化是中国式现代化的必由之路和重要标志,也是推动民族地区经济社会文化发展的驱动力。青海省h县地方政府将移民工程与城镇化发展战略相结合,将牧区人口向小城镇集中,形成了“两栖式”新型城镇化,表现为城镇与牧区互动频繁化,牧民生计模式多元化与生活方式城市化,其形成是畜牧业生产经营模式的发展性、县域公共服务的集中性与县城生活的丰富性等多元因素综合作用的结果。相较而言,牧民作为“能动的主体”嵌入中国式城乡二元结构,并且“半城半牧”的城镇化形态形成了草原牧区与城市社区的有机互动,有利于实现生态治理、民生保障与经济发展的系统目标。

关键词：牧区城镇化两栖式半城半牧生态治理

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