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5182铝合金的铸轧研究

5182铝合金的铸轧研究

Neuroinflammation as a therapeutic target in huntington's disease

2011全国铝及镁合金熔铸技术交流会

作者： T.haga M.Mtsuo D.Kunigo Y.hatanaka R.Nakamuta h.watari S.Kumai 秋海滨张明李梅 Osaka Institute of Technolongy 5-16-1 Omiya Asahiku Osaka City535-8585Japan Gunma University 1-5-1Tenjin ChoKiryu CityGunma376-8515Japan Tokyo Institute of Technology 4259NagatsudaMidorikuYokohama CityKanagawa226-8502Japan

采用双辊异径铸轧机和立式高速双辊铸轧机,并配合无需润滑的低碳钢辊套高速生产5182铝合金带材。结果表明,立式高速双辊铸轧机可以有效地生产5182铝合金,其铸轧速度较传统铸轧机速度高10倍,低碳钢辊套无润滑情况下生产5182铝合金也不粘... 详细信息

采用双辊异径铸轧机和立式高速双辊铸轧机,并配合无需润滑的低碳钢辊套高速生产5182铝合金带材。结果表明,立式高速双辊铸轧机可以有效地生产5182铝合金,其铸轧速度较传统铸轧机速度高10倍,低碳钢辊套无润滑情况下生产5182铝合金也不粘辊,可使铝合金薄带材的生产成本大大降低。

关键词：铸轧双辊铸轧机 5182铝合金带材

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Neural Regeneration Research 2025年第3期20卷 817-818页

作者： Andrea Kwakowsky Thulani h.Palpagama Center for Brain Research and Department of Anatomy and Medical Imaging Faculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand Pharmacology and Therapeutics School of MedicineGalway Neuroscience CentreUniversity of GalwayGalwayIreland

In 1872, George huntington presented his essay “On Chorea” to the Meigs and Mason Academy of Medicine and, in doing so, detailed a disease that would later bear his name. huntington's disease(hD) is a genetic, neurodegenerative disease that manifests as the loss of motor control,cognitive impairment,and mood and psychiatric changes in paents.

关键词： huntington inflammation Medicine

Glial response in the midcingulate cortex in huntington’s disease

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Neural Regeneration Research 2025年第1期20卷 207-208页

作者： Thulani h.Palpagama Andrea Kwakowsky Center for Brain Research and Department of Anatomy and Medical Imaging Faculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand Pharmacology and Therapeutics School of MedicineGalway Neuroscience CenterUniversity of GalwayGalwayIreland

huntington’s disease(hD)is a genetic disease characterized by the progressive degeneration of the striatum and *** can present with a variety of symptoms that can broadly be classified into motor symptoms,inclusive of choreatic movements and rigidity,mood and psychiatric symptoms,such as depression and apathy,and cognitive symptoms,such as cognitive *** causal mutation underlying hD results from an expansion of a CAG repeat sequence on the IT15 gene,resulting in the formation and accumulation of a mutant huntingtin protein.

关键词： huntington degeneration cortex

Comparative chemical sensor for detection of chromium(Ⅵ) in aqueous solution

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Optoelectronics Letters 2025年第1期21卷 21-27页

作者： Sura h.AL-REKABI A.A.ALWAhIB Electrical Technique Department Al Suwayrah Technical Institute Middle Technical University Laser and Optoelectronics Department University of Technology-Iraq

A process for purifying aqueous solutions containing heavy and toxic metals such as chromium（Cr） has been investigated. One of the extremely harmful pollutants in rivers and seawater is the heavy metal ions due to their direct impacts on human, animals and plants are hexavalent Cr（Ⅵ）. Consequently, highly sensitive sensor to detect Cr is essential. Surface plasmon resonance（SPR） technique has attracted huge research interest in detecting heavy metals specifically. In this study, three types of prism-based SPR sensor, gold（Au）/silver（Ag）, Au/polyaniline（PANI） and Au/titanium dioxide（TiO2） nanostructured films, are investigated as potential sensing material to detect the presence of Cr（Ⅵ） ions in water. The base Au layer with thickness of 48.3 nm is deposited on a glass slide for all sensors. For Au/Ag, Au/PANI nanofibers and Au/TiO2sensor films, the Cr（Ⅵ） concentration is varied from 1 ppm to 15 ppm with sensitivity of 0.270 °ppm-1, 0.082 °ppm-1and 0.039 °ppm-1, respectively. Based on these results, the Au/PANI nanofibers are the most sensitive to Cr（Ⅵ） among the tested sensing materials.

关键词： Titanium dioxide

Does mesenchymal stem cell’s secretome affect spinal sensory circuits?Implication for pain therapies

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Neural Regeneration Research 2025年第1期20卷 181-183页

作者： Francesco Ferrini Esri h.Juárez Adalberto Merighi Department of Veterinary Sciences University of TurinGrugliascoTOItaly Department of Psychiatry and Neuroscience UniversitéLavalQuébec CityQCCanada

Mesenchymal stem cells(MSCs)are multipotent adult stem cells of mesodermal origin that can be isolated from various tissues,including bone marrow,tooth pulp,adipose tissue,and umbilical *** have gained significant attention in regenerative medicine due to their ability to modulate the immune system and favor tissue *** enrich the medium in which they are cultivated with a broad range of bioactive molecules,including growth factors,cytokines,chemokines,enzymes,nucleic acids,and extracellular vesicles that collectively compose the MSC *** increasing number of pre-clinical studies suggest that delivering in vivo an MSC-conditioned medium(i.e.,the medium collected from MSC cultures after at least 3 days of exposure)exerts neuroprotective and anti-inflammatory effects in a variety of neurological conditions.

关键词： protective clinical collective

Dynamic stress concentration in an infinitely long cylindrical cavity due to a point spherical source embedded within a fluid-saturated poroelastic formation of infinite extent

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 139-156页

作者： h.hOSSEINI O.BALILAShAKI Department of Mechanical Engineering Faculty of EngineeringGolestan University

The effects of a harmonically exciting monopole source on an infinitely long cylindrical cavity embedded entirely within a fluid-saturated poroelastic formation of infinite extent are examined theoretically. It is assumed that the source is located outside the cavity at a specified distance from the borehole axis. The magnitudes of the hoop and radial stresses beside the pore pressures exerted on the interface and inside the porous medium surrounding the borehole are calculated and discussed. Biot's poroelastic modeling along with three types of boundary conditions for the cylindrical interface including the ideal fluid, empty borehole, and rigid inclusion with a hard boundary is employed for the analysis. Utilizing a proper translational addition theorem for expressing the incident spherical wave in terms of cylindrical wave expansions, the proposed boundary conditions at the interface are satisfied. Stresses are formulated by means of wave potential functions in a three-dimensional(3D) manner. The effects of the frequency and the radial distance between the source and borehole on the induced stresses are examined for the first cylindrical modes over frequency spectra. Two permeability conditions for the interface and three types of soils for the porous formation are considered throughout the analysis. To give an overall outline of the study, a numerical example is presented. The results clearly indicate that the distance is a key parameter and has considerable effects on the induced stress values. In addition, the interface permeability condition and soil characteristics play an important role in determining the dynamic response of the borehole. Finally,the obtained results are compared with the relevant analyses existing in the literature for some limit cases, and good agreement is achieved.

关键词： point source cylindrical cavity porous medium wave-field transformation stress concentration O353.4

Carbon Nanotube Coating on Titanium Substrate Modified with TiO_2 Nanotubes

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Journal of Wuhan University of Technology(Materials Science) 2011年第5期26卷 867-871页

作者：白玉 PARK Ilsong BAE Taesung KIM Kyounga watari Fumio UO Motohiro LEE Minho Department of Dental Biomaterials School of Dentistry and Institute of Oral BioscienceBrain Korea 21 ProjectChonbuk National University School of Materials Science and Engineering Inner Mongolia University of Technology Department of Conservative Dentistry Institute of Oral Bioscience and BK 21 ProjectSchool of DentistryChonbuk National University Biomedical Dental Materials and EngineeringDepartment of Oral Health ScienceGraduate School of Dental MedicineHokkaido University Advanced Biomaterials Section Graduate School of Medical and Dental SciencesTokyo Medical and Dental University

A combination of carbon nanotubes （CNTs） and titanium （Ti） modified with TiO2 nanotubes （TiO2 NTs） was fulfilled with the aim of improving bioactivity of Ti ***,well-ordered TiO2 NTs were prepared by the electrochemical anodization of Ti in an ethylene glycol electrolyte containing 1 wt% Nh4F and 10 wt% h2O at 20 V for 50 min,followed by ***,the carboxylated CNTs were coated onto the TiO2 NTs using electrophoretic deposition （EPD） *** growth of hydroxyapatite （hA） on the samples was investigated by soaking them in simulated body fluid （SBF）.The result showed the CNTs-coated Ti with the modification of TiO2 NTs （CNTs-TiO2 NTs） was more efficient to induce hA formation than the CNTs-coated smooth Ti （CNTs-Ti）.The vitro cell response was evaluated using osteoblast cells （MC3T3-E1）.The good cell proliferation and strong cell adhesion could be obtained on the CNTs-TiO2 *** results indicated that CNT coating on the Ti modified with TiO2 NTs could be potentially useful for the periodontal ligament combination on dental implants.

关键词： carbon nanotubes TiO2 nanotubes apatite-forming ability cell adhesion

Calcitonin and vitamin D3 have high therapeutic potential for improving diabetic mandibular growth

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International Journal of Oral Science 2016年第1期8卷 39-44页

作者： Mona A Abbassy Ippei watari Ahmed S Bakry Takashi Ono Ali h hassan Orthodontic Department Faculty of DentistryKing Abdulaziz UniversityJeddahSaudi Arabia Department of Orofacial Development and Function Division of Oral Health SciencesGraduate SchoolTokyo Medical and Dental UniversityTokyoJapan Alexandria University AlexandriaEgypt Conservative Dentistry Department Faculty of DentistryKing Abdulaziz UniversityJeddahSaudi Arabia Cariology and Operative Dentistry Department Graduate School of Medical and Dental SciencesTokyo Medical&Dental UniversityTokyoJapan Conservative Dentistry Department Faculty of DentistryAlexandria UniversityAlexandriaEgypt

The goal of this study was to assess the effect of the intermittent combination of an antiresorptive agent （calcitonin） and an anabolic agent （vitamin D3） on treating the detrimental effects of Type 1 diabetes mellitus （DM） on mandibular bone formation and growth. Forty 3-week-old male Wistar rats were divided into four groups： the control group （normal rats）, the control C＋D group （normal rats injected with calcitonin and vitamin D3）, the diabetic C＋D group （diabetic rats injected with calcitonin and vitamin D3） and the diabetic group （uncontrolled diabetic rats）. An experimental DM condition was induced in the male Wistar rats in the diabetic and diabetic C＋ D groups using a single dose of 60 ***-1 body weight of streptozotocin. Calcitonin and vitamin D3 were simultaneously injected in the rats of the control C＋D and diabetic C＋D groups. All rats were killed after 4 weeks, and the right mandibles were evaluated by micro-computed tomography and histomorphometric analysis. Diabetic rats showed a significant deterioration in bone quality and bone formation （diabetic group）. By contrast, with the injection of calcitonin and vitamin D3, both bone parameters and bone formation significantly improved （diabetic C＋ D group）（P 〈 0.05）. These findings suggest that these two hormones might potentially improve various bone properties.

关键词： type 1 diabetes mellitus mandibular bone structure mandibular bone formation micro-computed tomography bone histomorphometry

Flexible electricity price forecasting by switching mother wavelets based onwavelet transform and Long Short-Term Memory

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Energy and AI 2022年第4期10卷 95-102页

作者： Koki Iwabuchi Kenshiro Kato Daichi watari Ittetsu Taniguchi Francky Catthoor Elham Shirazi Takao Onoye Osaka University 1-5 YamadaokaSuitaOsaka 565-0871Japan imec Kapeldeef 753001 HeverleeBelgium ESAT KULeuvenKasteelpark Arenberg 103001 HeverleeBelgium EnergyVille Dennenstraat 7B-3600 GenkBelgium University of Twente Enschede7500 AENetherlands

Under dynamic pricing, stable and accurate electricity price forecasting on the demand side is essential forefficient energy management. We have developed a new electricity price forecasting model that providesconsistently accurate forecasts. The base prediction model decomposes the time series using wavelet transformand then predicts it by Long Short-Term Memory. Previous studies using this model have always decomposedtime series in the same way without changing the mother wavelet. however, this makes it difficult to respond tochanges in time series that vary daily or seasonally. Therefore, we periodically switch the mother wavelet, i.e.,flexibly change the time series decomposition method, to achieve stable and highly accurate electricity priceforecasting. In an experiment, the model improved prediction accuracy by up to 42.8% compared to predictionwith a fixed mother wavelet. Experimental results show that the proposed flexible forecasting method canconsistently provide highly accurate forecasts.

关键词： Dynamic pricing Electricity price forecast Wavelet transform Long Short-Term Memory neural network