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Cosmic—Ray Deficit from the Directions of the moon and the Sun Detected with the Tibet Air Shower Array

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西藏大学学报(社会科学版) 1993年第4期8卷 76-85页

作者： M.Amenomori Z.Cao L.K.Ding Z.Y.Feng hibino N.hotta Q.huang A.X.huo h.Y.Jia G.z.Jiang S.Q.Jiao F.Kajino K.Kasahara Labaciren D.M.Mei L.Meng X.R.Meng Mimaciren K.Mizutani J.Mu h.Nanjo M.Nishizawa Nusang A.Oguro M.Ohnishi I.Ohta To.Saito M.Sakata Z.Z.shi M.Shibata T.Shirai h.sugimoto X.X.Sun A.Tai K.Taira Y.h.Tan N.Tateyama S.Torii h.Wang C.Z.Wen Y.Yamamoto X.Y.Yao G.C.Yu P.Yuan T.Yuda J.G.Zeng C.S.Zhang h.M.Zhang L.Zhang Zhasang Zhaxiciren W.D.Zhou Department of Physics Hirosaki UniversityHirosakiJapan Institute of high Energy Physics Academia SinicaBeijingChina Departmetn of Physics Sorth West Jiaotong UniversityChengduChina Institute for Cosmic Ray Research University of TokyoTanashiJapan Faculty of Education Utsunomiya UniversityUtsunomiyaJapan Department of Physics Konan UniversityKobeJapan Faculty of Engineering Kanagawa UniversityYokohanaJapan Department of Mathematics and Physics Tibet UniversityLhasaChina Department of Physics saitama UniversityUrawaJapan Department of Physics Yunnan UniversityKunmingChina Faculty of Education Yokohama National UniversityYokohanaJapan Shonan Institute of Technology FujisawaJapan

Data from the Tibet air shower array were used to examine the cosmic ray shadows of the Moon and the Sun at energies around *** shadowing effect was clearly observed at the 5.8level for the Moon,while the shadow of the Sun was found in the direction away from the sun by 0.86°tothe west and 0.43°to the *** effect of the geomagnetic field has also been observed in the shadow of cosmic rays by the *** observed deflection of the sun’s shadow is briefly discussed in connection with the effect of the magnetic fields between the sun and the *** is the first observation of the effects of such magnetic fields on the cosmic ray *** maximum-likelihood analysis of the Moon data set shows that the angular resolutions of the array for showers with its mode energies 7TeVand 35TeV are 0.87°-0.13°+0.10°and 0.54°-0.08°+0.11°,respectively.

关键词：空气簇射宇宙射线阴影磁场 Gamma射线

Search for Steady Emission of 10—TeV Gamma Rays from the Crab Nebula,Cygnus X—3,and hercules X—1 Using the Tibet Air Shower Array

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西藏大学学报(社会科学版) 1993年第4期8卷 71-75页

作者： M.Amenomori Z.Cao.L.K.Ding Z.Y.Feng K.hibino N.hotta Q.huang A.X.huo h.Y.Jia G.Z.Jiang S.Q.Jiao F.Kajino K.Kasahara Labaciren D.M.Mei L.Meng X.R.Meng Mimaeiren K.Mizutani J.Mu h.Nanjo M.Nishizawa Nusang A.Oguro M.Ohnishi I.Ohta J.R.Ren To.saito M.Sakata Z.Z.Shi M.Shibata T.shirai h.sugimoto X.X.Sun A.Tai K.Taira Y.h.Tan N.Tateyama S.Torii h.Wang C.Z.Wen Y.Yamamoto X.Y.Yao G.C.Yu P.Yuan T.Yuda J.G.Zeng C.S.Zhang h.M.Zhang L.Zhang Zhasang Zhaxlclren W.D.Zhou Department of Physics Hirosaki UniuersityHirosakiJapan Institute of high Energy Physics Academia SinicaBeijingChina Department of Physics South West Jiaotong UniuersityChengduChina Institute for Cosmic Ray Research Uniuersity of TokyoTanashiJapan Faculty of Education Utsunomiya UniuersityUtsunomiyaJapan Departmem of Physics Konan UniuersityDepartmem of PhysicsKonan UniuersityKobeJapan Faculty of Engireering Kanagawa UniversityYokohamaJapan Department of Mathematics and Physics Tibet UniuersityLhasaChina Department of Physics Saitama UniuersityUrawaJapan Department of Physics Yunnan UniuersityKunmingChina Faculty of Education Yokohama National UniuersityYokohamaJapan Shonan Institute of Technology FujisawaJapan

寻找到高能和超高能的Gamma射线点源,在宇宙射线源方面有着极为重要的意义,本文就西藏羊八井观测到的空气簇射阵列及共它资料,对寻找稳定的10-TeV Gamma射线进行了分析论述。

关键词：西藏空气簇射 Gamma射线点源大气厚度 10TeV

基于TKO－CAMAC的羊八井EAS阵列数据采集系统

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核电子学与探测技术 1994年第5期14卷 278-283,262页

作者： Amen.,M 白占武曹臻丁林垲冯振勇 K.Jibion N.hotta 黄庆霍安祥贾焕玉江光佐焦善庆 F.Kajino K.Kasahara 拉巴次仁梅东明孟烈米玛次仁孟宪茹 K.Mizitani 木钧 h.Nanjo M.Nishizawa 努桑 M.Ohnishi I.Ohta 任敬儒 T.Saito M.Sakata 施志政 M.ShIBATA T.Shirai 孙欣新 h.sugimoto K.Taira 潭有恒 N.Tateyama S.Torii 王辉王家祥温诚忠 Y.Yamaoto 余光策袁澎 T.YUDA 曾家刚赵春华张春生张慧敏张力张鸣扎桑扎西次仁周文德中国科学院高能物理研究所西南交通大学物理系云南大学物理系西藏大学物理系日本弘前大学日本宇都宫大学日本琦玉大学日本东京大学宇宙线研究所日本神奈川大学日本横滨国立大学日本相模工业大学日本甲南大学

本义介绍一个基于ＴＫＯ－ＣＡＭＡＣ数据采集系统，该系统采集坐落在西藏羊八井的广延空气簇射阵列数据，它是由ＴＫＯ－ＡＭＡＣ系列插件和ＰＣ－３８６微机组成。除此以外，它还包括一个激光标定检测系统及由原子钟和ＧＰＳ（全球定... 详细信息

本义介绍一个基于ＴＫＯ－ＣＡＭＡＣ数据采集系统，该系统采集坐落在西藏羊八井的广延空气簇射阵列数据，它是由ＴＫＯ－ＡＭＡＣ系列插件和ＰＣ－３８６微机组成。除此以外，它还包括一个激光标定检测系统及由原子钟和ＧＰＳ（全球定位系统）组成的定时系统。

关键词：广延空气簇射太电子伏数据采集系统

西藏羊八井广延空气簇射阵列性能的Monte Carlo研究

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高能物理与核物理 1993年第5期17卷 385-390页

作者： M.Amenomori 白占武曹臻丁林垲冯振勇 K.hibino N.hotta 黄庆霍安祥贾焕玉江光佐焦善庆 F.Kajino K.Kasahara 拉巴次仁梅东明孟烈孟宪茹米玛次仁 K.Mizitani 木钧 h.Nanjo M.Nishizawa 努桑 M.Ohnishi I.Ohta 任敬儒 To.Saito M.Sakata 施志政 M.Shibata T.Shirai 孙欣新 h.sugimoto 台安 K.Taira 谭有恒 N.Tateyama S.Torii 王辉王家祥温诚忠 Y.Yamamoto 余光泽袁澎 T.Yuda 曾家刚赵春华张春生张慧敏张力张鸣扎桑扎西次仁周文德日本弘前大学中国西南交通大学物理系成都610031 中国科学院高能物理研究所北京100039 日本东京大学宇宙线研究所日本宇都宫大学日本甲南大学日本神奈川大学中国西藏大学数理系拉萨851501 日本琦玉大学中国云南大学物理系昆明650091 日本横滨国立大学日本相模工业大学

本文用Monte Carlo方法研究西藏羊八井空气簇射阵列性能。确定好事例判选标准.簇射中心定位精度达3.4m.原初粒子到达方向角分辨率好于1.1°.原初粒子能量按lgE_0=lg(0.45∑N_i)±0.226确定,其中E_0(TeV)为初级入射粒子能量,∑N_i为FT探... 详细信息

本文用Monte Carlo方法研究西藏羊八井空气簇射阵列性能。确定好事例判选标准.簇射中心定位精度达3.4m.原初粒子到达方向角分辨率好于1.1°.原初粒子能量按lgE_0=lg(0.45∑N_i)±0.226确定,其中E_0(TeV)为初级入射粒子能量,∑N_i为FT探测器上探测到的粒子总数.

关键词：广延空气簇射蒙特卡罗法空气簇射

Recent Progress in the Synthesis of Polymers Based on Carbon Dioxide

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复旦学报（自然科学版） 2005年第5期44卷 640-641页

作者： h. sugimoto S. Inoue Deparment of Industrial Chemistry Tokyo University of Science Tokyo 162-8601 JapanDeparment of Industrial Chemistry Tokyo University of Science Tokyo 162-8601 Japan

Carbon dioxide is the most fundamental carbon resource indispensable for all living systems including human being via photosynthesis by green plants. On the other hand, chemical utilization of carbon dioxide has been ... 详细信息

关键词：二氧化碳交互聚合反应环氧化物聚碳酸脂

Efficacy of tailored helicobacter pylori eradication therapy based on antibiotic susceptibility and CYP2C19 genotype

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World Journal of Gastroenterology 2014年第21期20卷 6400-6411页

作者： Mitsushige sugimoto Takahisa Furuta First Department of Medicine Hamamatsu University School of MedicineHamamatsu 431-3192Japan Center for Clinical Research Hamamatsu University School of MedicineHamamatsu 431-3192Japan

The cure rates of helicobacter pylori (h. pylori) eradication therapy using a proton pump inhibitor (PPI) and antimicrobial agents such as amoxicillin, clarithromycin, and metronidazole are mainly influenced by bacterial susceptibility to antimicrobial agents and the magnitude of the inhibition of acid secretion. Annual cure rates have gradually decreased because of the increased prevalence of h. pylori strains resistant to antimicrobial agents, especially to clarithromycin. Alternative regimens have therefore been developed incorporating different antimicrobial agents. Further, standard PPI therapy (twice-daily dosing) often fails to induce a long-term increase in intragastric ph > 4.0. Increasing the eradication rate requires more frequent and higher doses of PPIs. Therapeutic efficacy related to acid secretion is influenced by genetic factors such as variants of the genes encoding drug-metabolizing enzymes (e.g., cytochrome P450 2C19, CYP2C19), drug transporters (e.g., multidrug resistance protein-1; ABCB1), and inflammatory cytokines (e.g., interleukin-1β). For example, quadruple daily administration of PPI therapy potently inhibits acid secretion within 24 h, irrespective of CYP2C19 genotype. Therefore, tailored h. pylori eradication regimens that address acid secretion and employ optimal antimicrobial agents based on results of antimicrobial agent-susceptibility testing may prove effective in attaining higher eradication rates.

关键词： helicobacter pylori Tailored eradication therapy Proton pomp inhibitor Cytochrome P450 2C19 Clarithromycin

Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer

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World Journal of Gastroenterology 2010年第10期16卷 1188-1200页

作者： Mitsushige sugimoto Yoshio Yamaoka Takahisa Furuta Center for Clinical Research Hamamatsu University School of Medicine Department of Environmental and Preventive Medicine Faculty of MedicineOita University

Pro-inflammatory cytokines are produced in the gastric mucosa by inflammatory cells activated by chronic helicobacter pylori (h. pylori) infection. Polymorphisms of these cytokine genes are associated with individual differences in gastric mucosal cytokine mRNA level, which result in differences in gastric mucosal inflammation, acid inhibition and gastroduodenal disease risk in response to h. pylori infection. Although polymorphisms of interleukin (IL)-1B, IL-1RN and TNF-A have been reported to relate well with gastric cancer and peptic ulcer risk, those of IL-2, IL-4, IL-6 and IL-8 genes are unclear. In combined analyses using data from previous studies, we found that the risk of gastric non-cardia cancer development was significantly associated with IL-4-168 C allele (OR: 0.81, 95% CI: 0.69-1.00) and IL-4-590 T allele carrier status (0.61, 0.53-0.73), and IL-6-174 G/G genotype (2Pro-inflammatory cytokines are produced in the gastric mucosa by inflammatory cells activated by chronic helicobacter pylori (h. pylori) infection. Polymorphisms of these cytokine genes are associated with individual differences in gastric mucosal cytokine mRNA level, which result in differences in gastric mucosal inflammation, acid inhibition and gastroduodenal disease risk in response to h. pylori infection. Although polymorphisms of interleukin (IL)-1B, IL-1RN and TNF-A have been reported to relate well with gastric cancer and peptic ulcer risk, those of IL-2, IL-4, IL-6 and IL-8 genes are unclear. In combined analyses using data from previous stud- ies, we found that the risk of gastric non-cardia cancer development was significantly associated with IL-4-168 C allele (OR: 0.81, 95% CI: 0.69-1.00) and IL-4-590 T allele carrier status (0.61, 0.53-0.73), and IL-6-174 G/G genotype (2.02, 1.31-3.10). In peptic ulcer development, IL-2-330 G and IL-4-590 T allele carriers had a significantly decreased risk (0.37, 0.27-0.50 and 0.58, 0.34-0.99, respectively). Moreover, IL-2, IL-4, IL

关键词： helicobacter pylori Cytokines Genetic polymorphism Stomach neoplasms Peptic ulcer

Provenance Description of Metadata Vocabularies for the Long-term Maintenance of Metadata

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Journal of Data and Information Science 2017年第2期2卷 41-55页

作者： Chunqiu Li Shigeo sugimoto Graduate School of Library Information and Media StudiesUniversity of TsukubaJapan Faculty of Library Information and Media ScienceUniversity of TsukubaJapan

Purpose： The purpose of this paper is to discuss provenance description of metadata terms and metadata vocabularies as a set of metadata terms. Provenance is crucial information to keep track of changes of metadata terms and metadata vocabularies for their consistent maintenance. Design/methodology/approach： The W3C PROV standard for general provenance description and Resource Description Framework（RDF） are adopted as the base models to formally define provenance description for metadata ***： This paper defines a few primitive change types of metadata terms, and a provenance description model of the metadata terms based on the primitive change types. We also provide examples of provenance description in RDF graphs to show the proposed *** limitations： The model proposed in this paper is defined based on a few primitive relationships（e.g. addition, deletion, and replacement） between pre-version and post-version of a metadata term. The model is simplified and the practical changes of metadata terms can be more complicated than the primitive relationships discussed in the model. Practical implications： Formal provenance description of metadata vocabularies can improve maintainability of metadata vocabularies over time. Conventional maintenance of metadata terms is the maintenance of documents of terms. The proposed model enables effective and automated tracking of change history of metadata vocabularies using simple formal description scheme defined based on widely-used ***/value： Changes in metadata vocabularies may cause inconsistencies in the longterm use of metadata. This paper proposes a simple and formal scheme of provenance description of metadata vocabularies. The proposed model works as the basis of automated maintenance of metadata terms and their vocabularies and is applicable to various types of changes.

关键词： Metadata maintenance Metadata vocabulary Metadata term Metadata provenance Metadata longevity

Nutrition status and helicobacter pylori infection in patients receiving hemodialysis

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World Journal of Gastroenterology 2018年第15期24卷 1591-1600页

作者： Mitsushige sugimoto hideo Yasuda Akira Andoh Division of Digestive Endoscopy Shiga University of Medical Science Hospital First Department of Medicine Hamamatsu University School of Medicine Department of Gastroenterology Shiga University of Medical Science Hospital

Chronic kidney disease(CKD) patients receiving hemodialysis(hD) often develop gastrointestinal abnormalities over their long treatment period. In general, prognosis in such patients is poor due to the development of protein-energy wasting(PEW). Therefore, it is important to clarify the etiology of PEW and to establish better strategies to deal with this condition. Chronic helicobacter pylori(h. pylori) infection in the gastric mucosa has a close association with not only the development of peptic ulcer disease and gastric cancer, but is also associated with abnormal plasma and gastric mucosal ghrelin levels that are seen in malnutrition. It is unclear whether h. pylori infection of the gastric mucosa is directly associated with prognosis in hD patients by affecting ghrelin levels. Recent studies show that the prevalence of h. pylori infection in hD patients is significantly lower than in subjects with normal renal function. In the natural history of h. pylori infection in hD patients, the prevalence of infection decreases as the length of time on hD increases. The severity of gastric mucosal atrophy has been suggested as the major determinant of ghrelin levels in these patients, and eradication therapy of h. pylori improves nutritional status by increasing serum cholinesterase and cholesterol levels, especially in patients with mildto-moderate gastric mucosal atrophy. Prompt h. pylori eradication to inhibit the progress of gastric atrophy may be required to prevent this decrease in ghrelin levels and subsequent PEW and improve the prognosis of hD patients by improving their nutritional status.

关键词： helicobacter pylori hemodialysis Ghrelin Gastric mucosa Anti-bacterial agents