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一患儿眼眶淋巴管瘤的组织病理学研究

世界核心医学期刊文摘（眼科学分册） 2005年第6期1卷 52-53页

作者： Goto h. Usui M. okada S. 肖颖 Department of Ophthalmology Tokyo Medical University 6- 7- 1 Nishishinjuku Shinjuku-ku Tokyo 160- 0023 Japan

Background: There has been controversy over whether orbital lymphangioma is a true entity in the orbit or various venous malformations. Case: A 1- year-old girl was referred to us with subcutaneous induration of the right upper eyelid. Rapid enlargement of the eyelid mass with blepharoptosis and dislocation of the eyeball were noted within 1 week. A diagnosis of an orbital lymphangiomawas made from the clinical course and findings of magnetic resonance imaging. Surgical resection of the tumor was performed to prevent amblyopia. Observations: histopathologically, the lumen of the expanded cystic tumor consisted of a single layer of endothelium and was filled with erythrocytes as well as lymph. Immunohistochemical study revealed positive staining for factor VIII-related protein and CD31, weak positive staining for thrombomodulin, and negative staining for CD34 at the endothelium of the lymphangioma. The endothelium of the capillary vessels around the lymphangioma was positive for factor VIII-related protein, CD31, and CD34. Although a part of the tumor remained in the orbit postoperatively, orthophoria was achieved and no recurrence was observed for 2 years. Conclusion: Immunohistochemical study suggested that the cellular composition of the endothelium of the orbital lymphangiomawas different from that of the surrounding capillary vessels.

关键词：病理学研究淋巴管瘤上睑免疫组织化学眼球脱位实体肿瘤瘤体残留眼位皮下硬结囊样

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高强度铝活塞材料的开发

汽车与新动力 2013年第2期45卷 55-58页

作者： Koma h hayashi S Genma Y Matsuyama Y okada N Ikuno h 朱炳全

作为减少车辆二氧化碳排放的一种手段,减轻零件的质量显得越来越重要。介绍一种新开发的、具有高耐疲劳强度的新铸铝材料,以进一步减轻活塞质量。应用能形成均质显微结构的开发理念实现了这一目标,在这种材料结构中,添加了钛以生成细微... 详细信息

作为减少车辆二氧化碳排放的一种手段,减轻零件的质量显得越来越重要。介绍一种新开发的、具有高耐疲劳强度的新铸铝材料,以进一步减轻活塞质量。应用能形成均质显微结构的开发理念实现了这一目标,在这种材料结构中,添加了钛以生成细微组织,同时添加了适量的铁和锰,以形成一种具有良好高温稳定性的化合物。用这种新开发材料制造的活塞样品所做的试验显示,该材料的强度比传统材料的提高了14%,因而能提高发动机功率,并减轻活塞质量。

关键词：活塞铸铝材料疲劳强度组织

Acta Biomat:开发出可促进机体神经组织再生的新型网格纤维结构

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现代生物医学进展 2017年第18期17卷 I0002-I0003页

作者： Koji Suzuki[a] hiroyuki Tanaka[a] Mitsuhiro Ebara[b] Koichiro Uto[b] hozo Matsuoka[a] Shunsuke Nishimoto[a] Kiyoshi okada[a][c] Tsuyoshi Murase[a] hideki Yoshikawa[a] [a] Department of Orthopaedic Surgery Osaka University Graduate School of Medicine 2-2 Yamadaoka Suita Osaka 565-0871 Japan[b] International Center for Materials Nanoarchitectonics (WPI-MANA) National Institute for Materials Science (NIMS) 1-1 Namiki Tsukuba Ibaraki 304-0044 Japan[c] Medical Center for Translational and Clinical Research Osaka University Hospital 2-15 Yamadaoka Suita Osaka 565-0871 Japan

近日。一项刊登在国际杂志Acta Biomaterialia上的研究报告中。来自日本大阪大学的研究人员通过研究开发出了一种网格结构。其能够被缠绕在损伤的周围神经组织上来帮助促进损伤神经的再生并且恢复其功能。

关键词：损伤神经组织再生网格结构研究开发纤维结构机体日本大阪大学研究人员

Clinical and histopathological study of preoperative radiochemotherapy with concomitant docetaxel in patients with squamous cell carcinoma of the oral cavity

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中国口腔颌面外科杂志 2008年第B5期6卷 167-168页

作者： Takahiro Oneyama Akira Tanaka Syuji Toya Akira Yamoguchi Kazuhiko hiroyasu zumi Mataga Yasuo okada Oral and Maxillofacial Surgery The Nippon Dental University Niigata Hospital Department of Oral and Maxillofacial Surgery h The Nippon Dental University School of Life Dentistry at Niigata Department of Pathology The Nippon Dental University School of Life Dentistry at Niigatajapan

Purpose: A comparative study on therapeutic effects was performed on 29 patients with squamous cell carcinoma of the oral cavity in whom clinical and histopathological effects could be evaluated among patients with primary squamous cell carcinoma of the oral cavity treated in the Oral and Maxillofacial Surgery, Nippon Dental University Niigata hospital. Methods: The 11 patients in the concomitant docetaxel group consisted of six men and five women with a mean age of 53.8 years. The primary sites were the tongue in four patients, the upper gum in four and lower gum in one patient. The T classification was T2 in two cases, T3 in eight and T4a in one. The 18 patients in the non-concomitant group were mainly given cisplatin and 5-Fu and consisted of ten men and eight women with a mean age of 63.1 years. The primary site was the tongue in six patients, floor of the mouth in one, buccal mucosa in eight, upper gum in two and lower gum in three patients. The T classification was T2 in 11 cases, T3 in five and T4a in two. The basic treatment method was docetaxel at 50 mg/m2 and cisplatin at 50 mg/m2 on day 1 and 5-Fu at 250 mg/m2 on days 2 to 6. The therapeutic effects were evaluated clinically by macroscopic inspections, palpations, CT and MRI. The histopathological effects according to the Oboshi-Shimosato classification was judged from surgical excisioned speciemens. Results: In the clinical evaluation of therapeutic effects, one patient was NC, nine were PR and one CR. In the histological evaluation of therapeutic effects, four patients were IIa, two were lib, four were III and one was IVb. In the non-concomitant group, these figures were NC in three, PR in 13, PD in two patients clinically and I in one, IIa in nine,

关键词：口腔鳞状细胞癌组织病理学放射线疗法

ICRF heated Long-Pulse Plasma Discharges in LhD

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Plasma Science and Technology 2006年第1期8卷 28-32页

作者： R. KUMAZAWA T. SEKI T. MUTOh K. SAITO T. WATARI Y. NAKAMURA M. SAKAMOTO T. WATANABE S. KUBO T. ShIMOZUMA Y. YOShIMURA h. IGAMI Y. TAKEIRI Y. OKA K. TSUMORI M. OSAKABE K. IKEDA K. NAGAOKA O. KANEKO J. MIYAZAWA S. MORITA K. NARIhARA M. ShOJI S. MASUZAKI M. GOTO T. MORISAKI B. J. PETERSON K. SATO T. TOKUZAWA N. AShIKAWA K. NIShIMURA h. FUNABA h. ChIKARAIShI T. NOTAKE Y. TORII h. okada M. IChIMURA h. hIGAKI Y. TAKASE h. KASAhARA F. ShIMPO G.NOMURA C.TAKAhAShI M.YOKOTA A. KATO 赵燕平 J. S. YOON J. G. KWAK h. YAMADA K. KAWAhATA N. OhYABU K. IDA Y. NAGAYAMA N. NODA A. KOMORI S. SUDO O. MOTOJIMA National Institute for Fusion Science Toki Japan Kyusyu University Kasuga Japan Nagoya University Faculty of Engineering Nagoya Japan Kyoto University Institute of Advanced Energy Uji Japan Tsukuba University Plasma Research Center Tsukuba Japan Tokyo University Graduate School of Frontier Sciences Tokyo Japan Institute of Plasma Physics Chinese Academy of Sciences Hefei 230031 China KAERI 150 Deogjin-dong Yuseong-gu Daejeon Korea Rep.

A long-pulse plasma discharge for more than 30 *** achieved on the Largehelical Device(LhD).A plasma of n_e=0.8×10^(19)m^(-3)and T_(iO)=2.0 keV was sustained withP_(ICh)=0.52 MW,P_(ECh)=0.1 MW and averaged P_(NBI)=0.067 *** injected heatingenergy was 1.3 GJ,which was a quarter of the prepared RF heating *** of the keys to thesuccess of the experiment was a dispersion of the local plasma heat load to divertors,accomplishedby shifting the magnetic axis inward and outward.

关键词：长脉冲等离子体放电 LhD ICRF加热螺旋/仿星器构造稳定态操作

添加元素对Sm_2Fe_(17)C_x熔淬带材磁性能的改善

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电工合金 1993年第4期 25-30页

作者： S.Sugimoto K.Kurihara h.Nakamura M.okada M.homma 喻承寅

经过对熔淬前合金铸锭显微组织的研究,确认了在Sm_2(Fe_(0.9)Cr_(0.1))_(17)C_(1.6)合金中,Sm_2Fe_(17)相的构成,具有Th_2Zn_(17)类型的结构。Sm_2(Fe_(0.9)Cr_(0.1))_(17)C_(1.6)熔淬带材经温度为750℃退火30分钟后,显示出了672KAm^(-1)(8.4KOe)的矫顽力。对显微结构的研究表明,该带材的晶粒直径为50～150nm。使用X-射线衍射分析,并研究了各种材料的磁滞回线之后,发现随着退火温度的增加,导致相结构从TbCu_(17)类型向Th_2Zn_(17)类型转变。含Ga的Sm_2(Fe_(0.9)Ga_(0.1))_(17)C_(1.6)带材,在退火之后获得了680KAm^(-1)(8.5KOe)的矫顽力。进一步在Sm_2(Fe,Cr)_(17)C_(1.6)和Sm_2(Fe,Ga)_(17)C_(1.6)合金中添加Co、Mn等,也使其磁性能得到了改善.特别是合金Sm_2(Fe_(0.85)Ga_(0.1)Co_(0.05))_(17)C_(1.6)带材,经650℃、30分钟的退火处理后,获得了高达1008KAm^(-1)(12.6KOe)的矫顽力以及(Bh)_(max)为62.4KJm^(-3)(7.8MGOe)的磁能积。这是到目前为止所报导过的、Sm_2Fe_(17)C_x熔淬带材获得的最高磁性能。

关键词：铁磁材料添加元素磁性

Protocol liver biopsy is the only examination that can detect mid-term graft fibrosis after pediatric liver transplantation

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World Journal of Gastroenterology 2014年第21期20卷 6638-6650页

作者： Yukihiro Sanada Koshi Matsumoto Taizen Urahashi Yoshiyuki Ihara Taiichi Wakiya Noriki okada Naoya Yamada Yuta hirata Koichi Mizuta Department of Transplant Surgery Jichi Medical UniversityTochigi 329-0498Japan Department of Clinical Pathology Ebina General HospitalKanagawa Prefecture 243-0433Japan

AIM:To assessed the clinical significance of protocol liver biopsy(PLB)in pediatric liver transplantation(LT).METhODS:Between July 2008 and August 2012,89and 55 PLBs were performed in pediatric patients at two and five years after LT,*** assessed the histopathological findings using the Metavir scoring system,including activity(A)and fibrosis(F),and we identified factors associated with scores of≥A1 and≥*** results clarified the timing and effectiveness of ***:The incidences of scores of≥A1 and≥F1 were 24.7%and 24.7%,respectively,at two years after LT and 42.3%and 34.5%,respectively,at five *** risk factors in a multivariate analysis of a score of≥A1 at two years included≥2 h ofcold ischemic time,no acute cellular rejection and an alanine amino transaminase(ALT)level of≥20 IU/L(P=0.028,P=0.033 and P=0.012,respectively);however,no risk factors were identified for a score of≥***,no independent risk factors associated with scores of≥A1 and≥F1 at five years were identified using multivariate analysis.A ROC curve analysis of ALT at two years for a score of≥A1 demonstrated the recommended cutoff value for diagnosing≥A1 histology to be 20 IU/*** incidence of scores of≥A2 or≥F2 at two years after LT was 3.4%(three cases),and all patients had an absolute score of≥*** contrast to that observed for PLBs at five years after LT,the incidence of scores of≥A2 or≥F2 was 20.0%(11 cases),and all patients had an absolute score of≥*** all cases,the dose of immunosuppressants was increased after the PLB,and all ten patients who underwent a follow-up liver biopsy improved to scores of≤A1 or ***:PLB at two years after LT is an unnecessary examination,because the serum ALT level reflects portal *** addition,immunosuppressive therapy should be modulated to maintain the ALT concentration at a level less than 20 IU/*** at five years is an excellent examination for the detection of early reversible graft fibrosis bec

关键词： Protocol liver biopsy Graft fibrosis Immunosuppres

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含铌和铝的铁-铬-钴永磁合金

功能材料 1976年第Z1期 104-107页

作者： h. Kaneko. M. hommo. T. Fukunaga M. okada 周木森

构成15％Co、1％Nb、1％Al Fe-Cr-Co系的纵断面。这个系α相区的范围足够允许含25～30％Cr的合金在α1+α2混合间隙上任何温度的固溶处理。阶梯回火后它们所获得的磁性,Br=11.5～13KG,hc=500～600Oe,（Bh）max=4～5MGOe。从α相区通过... 详细信息

构成15％Co、1％Nb、1％Al Fe-Cr-Co系的纵断面。这个系α相区的范围足够允许含25～30％Cr的合金在α1+α2混合间隙上任何温度的固溶处理。阶梯回火后它们所获得的磁性,Br=11.5～13KG,hc=500～600Oe,（Bh）max=4～5MGOe。从α相区通过连续冷却也可以获得这些数据。Fe—Cr—Co系中添加Nb和Al有助于产生Fe—Cr—Co永磁材料。

关键词： Fe Cr Al Co AI 磁性永磁合金硬磁合金磁性合金

Amino acid profiles in relation to chronic periodontitis and rheumatoid arthritis

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Open Journal of Stomatology 2014年第2期4卷 49-55页

作者： Tetsuo Kobayashi Moe okada Satoshi Ito Daisuke Kobayashi Atsuko Shinhara Takahiko Muramatsu Tsuyoshi Kobayashi Ichiei Narita Kiyoshi Nakazono Akira Murasawa hiromasa Yoshie Division of Clinical Nephrology and Rheumatology Department of Homeostatic Regulation Developments Niigata University Graduate School of Medical and Dental Sciences Niigata Japan Division of Periodontology Department of Oral Biological Science Niigata University Graduate School of Medical and Dental Sciences Niigata Japan Institute for Innovation Ajinomoto Co. Inc. Kawasaki Japan Niigata Rheumatic Center Shibata Japan

Chronic periodontitis (CP) and rheumatoid arthritis (RA) are chronic inflammatory conditions, and share many pathologic features. Plasma amino acid profiles have been shown to be associated with RA, but their relevance to CP remains unclear. The aim of the present study is to evaluate amino acid profiles in relation to CP and RA. The study participants consisted of 62 patients with RA (RA group), 30 patients with CP (CP group) and 29 healthy controls (h group) in age-, gender-, smoking status-balanced condition. Clinical periodontal and rheumatologic parameter values and plasma levels of 21 amino acids, C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) were determined. Multiple comparison analyses revealed that the RA group exhibited similar periodontal conditions but significantly higher levels of CRP, IL-6, and TNF-α than the CP group (P histidine, ornithine, and alpha-aminobutyric acid) were significantly different in the concentrations among the three groups (P he RA group displayed significantly lower levels of glycine and histidine and significantly higher ornithine level than the CP and h groups (P he CP group showed significantly higher alpha-aminobutyric acid level than the RA and h groups (P hese four amino acids, a significantly positive correlation was found between ornithine level and % of sites with bleeding on probing (P = 0.006) in the RA group. These results suggest a possibility that profiles of four amino acids may play a role in the pathogenesis of CP and RA.

关键词： Amino Acid Chronic Periodontitis Rheumatoid Arthritis Case-Control Study