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Reproductive and Developmental Medicine 2024年第1期8卷 39-49页

作者： Suranga P.Kodithuwakku Ernest h.Y.ng william S.B.Yeung Kai-Fai Lee Department of Obstetrics and gynaecology LKS Faculty of MedicineThe University of Hong KongHong Kong SAR 999077China Department of Animal Science Faculty of AgricultureUniversity of PeradeniyaPeradeniya 20400Sri Lanka Shenzhen Key Laboratory of Fertility Regulation.The University of hong Kong-Shenzhen hospital Shenzhen 518053China

human fallopian tubes(FTs)play important roles in the whole reproductive *** are the site for the final maturation of gametes,fertilization,transport of preimplantation embryos,and early embryonic development before entering the *** these functions are critical in the establishment of a successful *** the embryo is in transit through the FT,the FT microenvironment changes through endocrine,paracrine,autocrine,and juxtacrine mechanisms which involve various hormones and bioactive substances mainly from the neighboring ***,the interactions between the embryo and the FT may be the earliest embryo-maternal communications that are essential for the establishment of *** review critically discusses the evidence of various hormonal and bioactive mediated control of the microenvironment in the FTs during the earliest embryo-maternal ***,we highlight existing gaps in the knowledge and the importance of exploring more of the physiology of FTs which will hold the key to producing high-quality embryos for patients seekingin vitro fertilization(IVF)treatments.

关键词： Fallopian tube Embryo Maternal-embryo communication hormonal control

Carbon dioxide enrichment affected flower numbers transiently and increased successful post-pollination development stably but without altering final acorn production in mature pedunculate oak (Quercus robur L.)

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Journal of Forestry Research 2024年第4期35卷 1-12页

作者： Ryan McClory Richard h.Ellis Martin Lukac Jo Clark Carolina Mayoral Kris M.hart Andrew R.g.Plackett A.Rob MacKenzie School of Agriculture Policy and DevelopmentUniversity of ReadingAgricultureEarley GateWhiteknights RoadPO Box 237Reading RG66EUUK Faculty of Forestry and wood Sciences Czech University of Life Sciences PraguePrague 165000Czechia Future Trees Trust Harwell Innovation CentreBuilding 173Curie AvenueHarwellOxford OX110QGUK Birmingham Institute of Forest Research University of BirminghamEdgbastonBirmingham B152TTUK School of Biosciences University of BirminghamEdgbastonBirmingham B152TTUK School of geography Earth and Environmental SciencesUniversity of BirminghamEdgbastonBirmingham B152TTUK

Acorn production in oak(Quercus spp.)shows considerable inter-annual variation,known as masting,which provides a natural defence against seed predators but a highly-variable supply of acorns for uses such as in commercial tree planting each *** emissions of greenhouse gases have been very widely reported to influence plant growth and seed or fruit size and quantity via the‘fertilisation effect’that leads to enhanced *** examine if acorn production in mature woodland communities will be affected by further increase in CO_(2),the contents of litter traps from a Free Air Carbon Enrichment(FACE)experiment in deciduous woodland in central England were analysed for numbers of flowers and acorns of pedunculate oak(Quercus robur L.)at different stages of development and their predation levels under ambient and elevated CO_(2) ***-annual variation in acorn numbers was considerable and cyclical between 2015 and 2021,with the greatest numbers of mature acorns in 2015,2017 and 2020 but almost none in *** numbers of flowers,enlarged cups,immature acorns,empty acorn cups,and galls in the litter traps also varied amongst years;comparatively high numbers of enlarged cups were recorded in 2018,suggesting *** at this site is a fruit maturation masting species(i.e.,the extent of abortion of pollinated flowers during acorn development affects mature acorn numbers greatly).Raising the atmospheric CO_(2) concentration by 150μL L^(−1),from early 2017,increased the numbers of immature acorns,and all acorn evidence(empty cups+immature acorns+mature acorns)detected in the litter traps compared to ambient controls by 2021,but did not consistently affect the numbers of flowers,enlarged cups,empty cups,or mature *** number of flowers in the elevated CO_(2) plots’litter traps was greater in 2018 than 2017,one year after CO_(2) enrichment began,whereas numbers declined in ambient *** with CO_(2) also increased the number o

关键词： Quercus robur L. Acorns Masting Pedunculate oak Carbon dioxide

Pervasive Attentive Neural Network for Intelligent Image Classification Based on N-CDE’s

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Computers, Materials & Continua 2024年第4期79卷 1137-1156页

作者： Anas w.Abulfaraj Department of Information Systems Faculty of Computing and Information TechnologyKing Abdulaziz UniversityRabigh21911Saudi Arabia

The utilization of visual attention enhances the performance of image classification *** attentionbased models have demonstrated notable performance,but many of these models exhibit reduced accuracy when confronted with inter-class and intra-class similarities and ***-Controlled Differential Equations(N-CDE’s)and Neural Ordinary Differential Equations(NODE’s)are extensively utilized within this ***’s possesses the capacity to effectively illustrate both inter-class and intra-class similarities and differences with enhanced *** this end,an attentive neural network has been proposed to generate attention maps,which uses two different types of N-CDE’s,one for adopting hidden layers and the other to generate attention *** distinct attention techniques are implemented including time-wise attention,also referred to as bottom N-CDE’s;and element-wise attention,called topN-CDE’***,a trainingmethodology is proposed to guarantee that the training problem is sufficiently *** classification tasks including fine-grained visual classification andmulti-label classification,are utilized to evaluate the *** proposedmethodology is employed on five publicly available datasets,including CUB-200-2011,ImageNet-1K,PASCAL VOC 2007,PASCAL VOC 2012,and MS *** obtained visualizations have demonstrated that N-CDE’s are better appropriate for attention-based activities in comparison to conventional NODE’s.

关键词： Differential equations neural-controlled DE image classification attention maps N-CDE’s

Current resistance status of Aedes aegypti and Aedes albopictus populations in Penang Island,Malaysia

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Asian Pacific Journal of Tropical Medicine 2024年第10期17卷 445-455页

作者： Kin hoong ng wan Fatma Zuharah Medical Entomology Laboratory School of Biological SciencesUniversiti Sains MalaysiaMalaysia11900PenangMalaysia

Objective:To determine the current insecticide resistance status of Aedes(Ae.)aegypti and *** to four insecticides,namely 0.05%deltamethrin,0.75%permethrin,5%malathion and 0.25%pirimiphos-methyl using the world health Organisation(whO)susceptibility test ***:Adult bioassays were carried out using the standard protocol of the world health *** F1 generation urban and suburban field strains of *** and *** were tested against pyrethroid and organophosphate insecticides,including the presence of piperonyl butoxide(PBO)in four replicates of 25 non-blood-fed female mosquitoes ranging from 3 to 5 days *** Vector Control Research Unit(VCRU)laboratory strain served as a reference ***:In this study,0.05%deltamethrin demonstrated a lower value of knockdown time when 50%of the mosquito population died(KT50)and knockdown time when 95%of the mosquito population died(KT95),which is significantly more effective compared to 0.75%permethrin against adult female ***(urban and suburban)and ***(urban and suburban)(ANOVA,Pwhile,5%malathion was a more effective insecticide,amounting to the shorter KT50 and KT95 compared to 0.25%pirimiphos-methyl against ***(urban and suburban)and ***(urban and suburban).*** urban and *** suburban performed a higher resistance ratio(RR)towards both 0.05%deltamethrin and 0.75%permethrin due to the wide use of permethrin in dengue vector control programs in ***,*** urban and suburban have lower resistance than *** urban and suburban towards 0.05%deltamethrin and 0.75%permethrin at 24 hours *** addition of PBO with these insecticides successfully reduced knockdown time(KT50 and KT95)values of most of the *** and *** field strains except PBO+0.75%permethrin against *** ***:The addition of PBO to insecticides has significantly reduced the knockdown time(KT50

关键词： Aedes Insecticide resistance Mosquito Organophosphates Pyrethroids Vector control

The magnetosheath at high spectral resolution

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Earth and Planetary Physics 2024年第1期8卷 234-246页

作者： K.D.Küntz D.Koutroumpa w.R.Dunn A.Foster F.S.Porter D.g.Sibeck B.walsh The henry A.Rowland Department of Physics and Astronomy Johns Hopkins University3701 San Martin DriveBaltimoreMD21218USA NASA goddard Space Flight Center 8800 Greenbelt RoadGreenbeltMD 20771USA LATMOS-OVSQ CNRSUVSQ Paris-SaclaySorbonne Université11 Boulevard d’Alembert78280GuyancourtFrance Department of Physics and Astronomy University College LondonLondonUK The Centre for Planetary Science at UCL/Birkbeck Gower StreetLondon WC1E 6BTUK Center for Astrophysics Harvard University&Smithsonian Institution60 Garden StreetCambridgeMA 02138USA Center for Space Physics Boston University110 Cummington MallBostonMAUSA

while we eagerly anticipate SMILE’s(Solar wind Magnetosphere Ionosphere Link Explorer)unprecedented X-ray observations of the Earth’s magnetosheath and the initiation of a new era of magnetospheric research,it seems appropriate to look ahead to the abilities of the next generation of astrophysics *** these,the Line Emission Mapper(LEM),a large aperture micro-calorimeter based mission,is currently planned to be able to observe the magnetosheath at high spectral resolution(~2 eV).with a field of view of~30′,LEM will allow higher spatial resolution and higher cadence measurement of the motion of a very small portion of the magnetopause over relatively short periods of time(multiple hours),complementing SMILE’s global ***’s strength is its spectral *** will be able to measure the abundance of a broad range of elements and ionization states,many of which are inaccessible to current in situ instruments,and will be able to separate the emission from the magnetosheath from the emission from the cosmic X-ray background using the difference in their relative velocities.

关键词： magnetosheath charge exchange solar wind abundances

Origin and evolution of a new tetraploid mangrove species in an intertidal zone

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Plant Diversity 2024年第4期46卷 476-490页

作者： hui Feng Achyut Kumar Banerjee wuxia guo Yang Yuan Fuyuan Duan wei Lun ng Xuming Zhao Yuting Liu Chunmei Li Ying Liu Linfeng Li Yelin huang State Key Laboratory of Biocontrol and guangdong Provincial Key Laboratory of Plant Resources School of Life SciencesSun Yat-sen UniversityGuangzhou 510275GuangdongChina Department of Bioengineering Zhuhai Campus of Zunyi Medical UniversityZhuhai 519041GuangdongChina China-ASEAN College of Marine Sciences Xiamen University MalaysiaSepang 43900SelangorMalaysia School of Agriculture Sun Yat-sen UniversityShenzhen 518107GuangdongChina School of Ecology Sun Yat-sen UniversityShenzhen 518107GuangdongChina

Polyploidy is a major factor in the evolution of plants,yet we know little about the origin and evolution of polyploidy in intertidal *** study aimed to identify the evolutionary transitions in three truemangrove species of the genus Acanthus distributed in the Indo-west Pacific *** this purpose,we took an integrative approach that combined data on morphology,cytology,climatic niche,phylogeny,and biogeography of 493 samples from 42 geographic *** results show that the Acanthus ilicifolius lineage distributed east of the Thai-Malay Peninsula possesses a tetraploid karyotype,which is morphologically distinct from that of the lineage on the west *** haplotype networks and phylogenetic trees for the chloroplast genome and eight nuclear genes reveal that the tetraploid species has two sub-genomes,one each from *** and ***,the paternal and maternal parents,*** structure analysis also supports the hybrid speciation history of the new tetraploid *** two sub-genomes of the tetraploid species diverged from their diploid progenitors during the *** niche models revealed that the tetraploid species not only occupied the near-entire niche space of the diploids,but also expanded into novel *** findings suggest that *** species distributed on the east side of the Thai-Malay Peninsula should be regarded as a new species,***,which originated from hybridization between *** and ***,followed by chromosome *** is the first report of a true-mangrove allopolyploid species that can reproduce sexually and clonally reproduction,which explains the long-term adaptive potential of the species.

关键词： Acanthus Allopolyploid Biogeography Evolution hybridization Polyploidy

Desialylated Platelet Clearance in the Liver is a Novel Mechanism of Systemic Immunosuppression

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Research 2024年第3期2023卷 35-50页

作者： June Li Danielle Karakas Feng Xue Yingyu Chen guangheng Zhu Yeni h.Yucel Sonya A.MacParland haibo Zhang John w.Semple John Freedman Qizhen Shi heyu Ni Department of Laboratory Medicine and Pathobiology University of TorontoTorontoONCanada Toronto Platelet Immunobiology group TorontoONCanada Keenan Research Centre for Biomedical Science of St.Michael's hospital TorontoONCanada Canadian Blood Services Centre for Innovation TorontoONCanada Departments of Pediatrics Medical College of WisconsinMilwaukeeWIUSA Blood Research Institute Versiti WisconsinMilwaukeeWIUSA Departments of Ophthalmology and Vision Sciences Medicine University of TorontoTorontoONCanada Faculty of Engineering and Architectural Science Ryerson UniversityTorontoONCanada Multi-Organ Transplant Program Toronto General Hospital Research InstituteTorontoONCanada Department of Immunology University of TorontoTorontoONCanada Critical Care Medicine Department ofAnesthesiology and PainUniversity of TorontoTorontoONCanada Department of Physiology University of TorontoTorontoONCanada Department of Pharmacology University of TorontoTorontoONCanada. Division of hematology and Transfusion Medicine Lund UniversityLundSweden clinical Immunology and Transfusion Medicine Ofice of Medical ServicesRegion SkaneLundSweden Department of Medicine University of TorontoTorontoONCanada Children's Research Institute Children's WisconsinWauwatosaWIUSA Midwest Athletes Against Childhood Cancer Fund Research Center MilwaukeeWIUSA.

Platelets are small, versatile blood cells that are critical for hemostasis/thrombosis. Local platelet accumulation is a known contributor to proinflammation in various disease states. however, the anti-inflammatory/immunosuppressive potential of platelets has been poorly explored. here, we uncovered, unexpectedly, desialylated platelets (dPLTs) down-regulated immune responses against both platelet-associated and -independent antigen challenges. Utilizing multispectral photoacoustic tomography, we tracked dPLT trafficking to gut vasculature and an exclusive Kupffer cell-mediated dPLT clearance in the liver, a process that we identified to be synergistically dependent on platelet glycoprotein Ibα and hepatic Ashwell–Morell receptor. Mechanistically, Kupffer cell clearance of dPLT potentiated a systemic immunosuppressive state with increased anti-inflammatory cytokines and circulating CD4+ regulatory T cells, abolishable by Kupffer cell depletion. Last, in a clinically relevant model of hemophilia A, presensitization with dPLT attenuated anti-factor VIII antibody production after factor VIII ( infusion. As platelet desialylation commonly occurs in daily-aged and activated platelets, these findings open new avenues toward understanding immune homeostasis and potentiate the therapeutic potential of dPLT and engineered dPLT transfusions in controlling autoimmune and alloimmune diseases.

关键词： Platelet transfusion homeostasis

holographic dark energy in non-conserved gravity theory

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Communications in Theoretical Physics 2024年第4期76卷 126-133页

作者： h R Fazlollahi Institute of gravitation and Cosmology Peoples Friendship University of Russia(RUDN University)6 Miklukho-Maklaya StMoscow117198Russia

Recently, reconsidering the Rastall idea T_(μ;νν)^(v)=α_(,μ) through relativistic thermodynamics gives a new form for the scalar field α which led us to construct modern modified theory of gravity debugged ‘non-conserved gravity theory’ Fazlollahi 2023 Euro. Phys. J. C 83 923. This theory unlike other modified theories of gravity cannot directly explain the current acceleration expansion in the absence of the cosmological constant and or existence of other forms of dark energy. hence, in this study we have reinvestigated holographic dark energy Ρ_(X)~h^(2) in the non-conserved theory of gravity. In this context, the density and pressure of dark energy depend on the non-conserved term and density of the dust matter field. As shown, due to non-conservation effects on large-scale structures, unlike the original holographic model, our model onsets an acceleration epoch for the current Universe satisfies observations. Moreover, the interaction and viscous scenarios are studied for this model.

关键词： non-conserved gravity covariant form of thermodynamics holographic dark energy

Construction of 2D/2D Ti_(3)C_(2)T_(x)MXene/CdS heterojunction with photothermal effect for efficient photocatalytic hydrogen production

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Journal of Materials Science & Technology 2024年第4期171卷 1-9页

作者： T.Y.huang Z.Yang S.Y.Yang Z.h.Dai Y.J.Liu J.h.Liao g.Y.Zhong Z.J.Xie Y.P.Fang S.S.Zhang Key Laboratory for Biobased Materials and Energy of Ministry of Education Guangdong Laboratory for Lingnan Modern AgricultureCollege of Materials and EnergySouth China Agricultural UniversityGuangzhou 510643China School of Physics and Optoelectronics South China University of TechnologyGuangzhou 510640China School of Chemical Engineering and Energy Technology Guangdong Provincial Key Laboratory of Distributed Energy SystemsDongguan University of TechnologyDongguan 523808China

The insensitivity of semiconductors to visible and infrared light is a key constraint on the utilization of light energy in photocatalytic *** photocatalysts with full-spectrum absorption through surface engineering is an effective approach to fully harnessing light energy in semiconductor ***,a novel stable Ti_(3)C_(2)T_(x)MXene/CdS heterojunction catalyst is obtained by in-situ epitaxial growth of two-dimensional(2D)CdS nanosheets on 2D MXene interface via a solvothermal *** exceptional light absorption properties of MXene confer outstanding full-spectrum driven photocat-alytic hydrogen evolution capability upon the heterogeneous *** unique 2D/2D structure effectively mitigated the recombination of photogenerated carriers,enhancing the photocatalytic performance of the ***,the composite catalyst exhibits a significantly higher surface temperature of 80.4℃under visible light irradiation at an intensity of 0.1 w/cm^(2),which is 1.84 times higher than that of *** irradiation of visible and near infrared light,the composite catalyst with photothermal ef-fect demonstrates a remarkable hydrogen evolution rate of 65.4 mmol g^(-1)h^(-1),which is 7.2 times higher than that of CdS *** study introduces a novel approach for constructing full-spectrum absorption catalysts and expands the application of the photothermal effect in photocatalytic hydrogen evolution research.

关键词： Two-dimensional structure heterostructure Photothermal effect Photocatalyst hydrogen evolution

Foam rolling and stretching do not provide superior acute flexibility and stiffness improvements compared to any other warm-up intervention: A systematic review with meta-analysis

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Journal of Sport and health Science 2024年第4期13卷 509-520页

作者： Konstantin warneke gerit Plöschberger Lars h.Lohmann Eric Lichtenstein Daniel Jochum Stanislav D.Siegel Astrid Zech David g.Behm Institute of Sport Science University of KlagenfurtKlagenfurt am Wörthersee 9020Austria Department of human Motion Science and Exercise Physiology Friedrich Schiller UniversityJena 07749Germany Department Sport Exercise and HealthUniversity of BaselBasel 4052Switzerland Department of health Sciences and Technology ETH ZurichZurich 8092Switzerland School of human Kinetics and Recreation Memorial University of NewfoundlandSt.JohnsNL A1C 5S7Canada

Background:Acute improvement in range of motion(ROM)is a widely reported effect of stretching and foam rolling,which is commonly explained by changes in pain threshold and/or musculotendinous ***,these effects were also reported in response to various other active and passive interventions that induce responses such as enhanced muscle ***,we hypothesized that acute ROM enhancements could be induced by a wide variety of interventions other than stretching or foam rolling that promote an increase in muscle ***:After a systematic search in PubMed,web of Science,and SPORTDiscus databases,38 studies comparing the effects of stretching and foam rolling with several other interventions on ROM and passive properties were *** studies had 1134 participants in total,and the data analysis resulted in 140 effect sizes(ESs).ES calculations were performed using robust variance estimation model with ***:Study quality of the included studies was classified as fair(PEDro score=4.58)with low to moderate certainty of *** showed no significant differences in ROM(ES=0.01,p=0.88),stiffness(ES=0.09,p=0.67),or passive peak torque(ES=-0.30,p=0.14)between stretching or foam rolling and the other identified *** plots revealed no publication ***:Based on current literature,our results challenge the established view on stretching and foam rolling as a recommended component of warm-up *** lack of significant difference between interventions suggests there is no need to emphasize stretching or foam rolling to induce acute ROM,passive peak torque increases,or stiffness reductions.

关键词： Range of motion Passive properties Muscletendon unit Muscle tissue