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Disordered Structure and Reversible Phase Transformation from K-Birnessite to Zn-Buserite Enable h.g.-Performance Aqueous Zinc-lon Batteries

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Energy & Environmental Materials 2024年第3期7卷 100-111页

作者： nibagani naresh Suyoon Eom Sang Jun Lee Su hwan Jeong Ji-Won Jung Young hwa Jung Joo-hyung kim Department of Materials Engineering and Convergence Technology Gyeongsang National University(GNU)Jinju 52828South Korea School of Material Science and Engineering(Ceramic Engineering) Gyeongsang National University(GNU)Jinju 52828South Korea School of Materials Science and Engineering University of Ulsan(UOU)Ulsan 44776South Korea PLS-ⅡBeamline Division Pohang Accelerator Laboratory(PAL)Pohang 37673South Korea

The layeredδ-MnO_(2)(dMO)is an excellent cathode material for rechargeable aqueous zinc-ion batteries owing to its large interlayer distance(~0.7 nm),h.g. capacity,and low cost;however,such cathodes suffer from structural degradation during the long-term cycling process,leading to capacity *** this study,a Co-doped dMO composite with reduced graphene oxide(gC-dMO)is developed using a simple cost-effective hydrothermal *** degree of disorderness increases owing to the hetero-atom doping and graphene oxide *** is demonstrated that layered dMO and gC-dMO undergo a structural transition from K-birnessite to the Zn-buserite phase upon the first discharge,which enhances the intercalation of Zn^(2+)ions,h_(2)O molecules in the layered *** gC-dMO cathode exhibits an excellent capacity of 302 mAh.g.(-1)at a current density of 100 mAg^(-1)after 100 cycles as compared with the dMO cathode(159 mAhg^(-1)).The excellent electrochemical performance of the gC-dMO cathode owing to Co-doping and graphene oxide sheets enhances the interlayer gap and disorderness,and maintains structural stability,which facilitates the easy reverse intercalation and de-intercalation of Zn^(2+)ions and h_(2)O ***,gC-dMO is a promising cathode material for large-scale aqueous ZIBs.

关键词： aqueous zinc-ion batteries birnessite buserite disordered structure phase transformation

SUV39h1-driven nFATc1 methylation is essential for the c-Cbl-mediated degradation of nFATc1 in an osteoclast lineage

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genes & Diseases 2024年第4期11卷 86-89页

作者： Do-Won Jeong hye-Jin kim Jong-Wan Park Seulbee Lee hyeryeon Jung Eugene C.Yi nacksung kime Yang-Sook Chun Department of Biomedical Sciences Seoul National University College of MedicineSeoul 03080Republic of Korea Department of Physiology Seoul National University College of MedicineSeoul 03080Republic of Korea Ischemic/hypoxic Disease Institute Seoul National University College of MedicineSeoul 03080Republic of Korea Department of Molecular Medicine and Biopharmaceutical Sciences Graduate School of Convergence Science and Technology and College of Medicine Or College of PharmacySeoul National UniversitySeoul 03080Republic of Korea Department of Pharmacology Chonnam National University Medical SchoolGwangju 61469Republic of Korea

Bone undergoes continuous remodeling by tightly-coordinated actions of bone-resorbing osteoclasts and boneforming osteoblasts.1 Recent studies document that the dysregulation of histone methylation profiles is associated with the progression of ***,the specific epigenetic modifiers are incompletely *** this study,we demonstrate an inhibitory role of a variegation 3-9 homolog 1(SUV39h1)in osteoclast formation.

关键词： osteoclast remodeling incomplete

The efect of the couple stress parameter and Prandtl number on the transient natural convection flow over a vertical cylinder

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Acta Mechanica Sinica 2013年第5期29卷 649-656页

作者： h.P.Rani g.Janardhana Reddy Chang nyung kim Department of Mathematics National Institute of TechnologyWarangal-506004 AP India Department of Mechanical Engineering College of Advanced Technology (Industrial Liaison Research Institute)Kyung Hee UniversityGyeonggi-do 446-701 Korea

An analysis is performed to study transient free convective boundary layer flow of a couple stress fluid over a vertical cylinder, in the absence of body couples. The solution of the time-dependent non-linear and coupled governing equations is carried out with the aid of an unconditionally stable Crank-nicolson type of numerical scheme. numerical results for the steady-state velocity, temperature as well as the time histories of the skin-friction coefficient and nus- selt number are presented graphically and discussed. It is seen that for all flow variables as the couple stress control parameter, Co, is amplified, the time required for reaching the temporal maximum increases but the steady-state decreases.

关键词： Couple stress fluid natural convection Vertical cylinder Finite difference method

Portable System for CWA Detection Using Micro Array gas Sensor

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稀有金属材料与工程 2006年第A3期35卷 124-128页

作者： J.h.Kwak Y.T.Lim g.h.kim n.J.Choi h.D.Park g.h.Rue J.S.huh J.C.kim D.D.Lee School of Electrical Engineering and Computer Science Kyungpook National UniversityDaegu 1370Korea Electronics and Telecommunications Research Institute Future Technology Research Division New Functional Information Devices TeamGajeongYuseong-GuDaejeon 161 Korea Korea Electronics Technology Institute Yatap-DongBundang-GuSeongnam-SiGyeonggi-Do #68Korea Department of Materials Science and Metallurgy Kyungpook National UniversityDaegu 1370Korea Department of Chemical Engineering Kyungpook National UniversityDaegu 1370Korea

Biochemistry weapon is raising new tools of war and *** research is an experiment about portable system for CWAs (chemical warfare agents) detection using micro array gas *** were divided into four types such as blood, nerve,vesicant,and choking *** detect various CWAs,semiconductor thick film sensor array based on tin oxide was fabricated and their gas responses were *** temperature was range of 250℃to 350℃and gas concentration was range of 0.1μg/g to 10μg/*** array was measured as operating temperatures,concentrations for four simulant agents of *** parameters from results were carried out classification among CWAs through the principal component analysis (PCA).Also,classification of gases is studied using adaptive resonance theory (ART) that is one of neural network *** displayed using PDA system.

关键词： SnO2 chemical warfare agents(CWAs) portable system ART array PCA

基于RSV预融合F蛋白的母体疫苗-早产和其他结局

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中国临床药理学杂志 2024年第9期40卷 1330-1330页

作者： DIEUSSAERT I kim J h LUIK S 王超群

妊娠期间接种呼吸道合胞病毒(RSV)疫苗可以保护婴儿免受RSV疾病的侵害。因此需要一种基于RSV预融合F蛋白的候选母源疫苗(RSVPreF3-Mat)的有效性和安全性数据。研究进行了一项涉及18~49岁孕妇的3期试验,以评估RSVPreF3-Mat的有效性和安... 详细信息

妊娠期间接种呼吸道合胞病毒(RSV)疫苗可以保护婴儿免受RSV疾病的侵害。因此需要一种基于RSV预融合F蛋白的候选母源疫苗(RSVPreF3-Mat)的有效性和安全性数据。研究进行了一项涉及18~49岁孕妇的3期试验,以评估RSVPreF3-Mat的有效性和安全性。这些妇女在妊娠24周0天至34周0天以2:1的比例随机分配接受RSVPreF3-Mat或安慰剂。主要结局是出生至6个月龄婴儿出现任何或严重医学评估的RSV相关下呼吸道疾病,以及出生至12个月龄婴儿的安全性。

关键词：下呼吸道疾病有效性和安全性安慰剂 F蛋白随机分配 RSV 疫苗妊娠期间

Electron-Cyclotron Laser Using Free-Electron Two-Quantum Stark Radiation in a Strong Uniform Axial Magnetic Field and an Alternating Axial Electric Field in a Voltage-Supplied Pill-Box Cavity

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Chinese Physics Letters 2016年第3期33卷 56-59页

作者： S.h.kim Church Road 9236 Dallas Texas 75231 USA

We consider the radiation from the beam electrons traveling in a strong uniform axial magnetic field and an axial alternating electric field of wavelength Aw generated by a voltage-supplied pill-box cavity. The beam electrons emit genuine laser radiation that propagates only in the axial direction through free-electron two- quantum Stark radiation. We find that laser radiation takes place only at the expense of the axial kinetic energy when Aw 〈〈 c/（ωc/γ）, where ωc/γ is the relativistic electron--cyclotron frequency. We formulate the laser power based on quantum-wiggler electrodynamics, and envision a laser of length lore with estimated power 0.1 gW/（kA） in the 10-4 cm wavelength range.

关键词： of on in that Electron-Cyclotron Laser Using Free-Electron Two-Quantum Stark Radiation in a Strong Uniform Axial Magnetic Field and an Alternating Axial Electric Field in a Voltage-Supplied Pill-Box Cavity is Stark

Optimal deployment schedule of an active twist rotor for performance enhancement and vibration reduction in h.g.-speed flights

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Chinese Journal of Aeronautics 2017年第4期30卷 1427-1440页

作者： Young h.YOU Sung n.JUng Chang J.kim Department of Aerospace Information Engineering Konkuk University Seoul 05019 Republic of Korea

The best active twist schedules exploiting various waveform types are sought taking advantage of the global search algorithm for the reduction of hub vibration and/or power required of a rotor in h.g.-speed conditions. The active twist schedules include two non-harmonic inputs formed based on segmented step functions as well as the simple harmonic waveform input. An advanced Particle Swarm assisted genetic Algorithm（PSgA） is employed for the optimizer. A rotorcraft Computational Structural Dynamics（CSD） code CAMRAD II is used to perform the rotor aeromechanics analysis. A Computation Fluid Dynamics（CFD） code is coupled with CSD for verification and some physical insights. The PSgA optimization results are verified against the parameter sweep study performed using the harmonic actuation. The optimum twist schedules according to the performance and/or vibration reduction strategy are obtained and their optimization gains are compared between the actuation cases. A two-phase non-harmonic actuation schedule demonstrates the best outcome in decreasing the power required while a four-phase non-harmonic schedule results in the best vibration reduction as well as the simultaneous reductions in the power required and vibration. The mechanism of reduction to the performance gains is identified illustrating the section airloads, angle-of-attack distribution, and elastic twist deformation predicted by the present approaches.

关键词： Active twist h.g.-speed flight hub vibration non-harmonic Power required

Positive regulation of cell proliferation by the miR-1290-EhhADh axis in hepatocellular carcinoma

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Cancer Communications 2024年第6期44卷 705-709页

作者： Jinkwon Lee gyeonghwa kim Tae-Su han Eunsun Jung Taesang Son Kwangho kim Kiyoon Kwon Yuna Roh Tae Young Ryu In hwan Tae Yunsang Kang Byungheon Lee Yu Rim Lee Soo Young Park Won Young Tak Dae-Soo kim Mi-Young Son Keun hur hyun-Soo Cho Stem Cell Convergence Research Center Korea Research Institute of Bioscience and BiotechnologyDaejeonRepublic of Korea Department of Bioscience Korea University of Science and TechnologyDaejeonRepublic of Korea Department of Biochemistry and Cell Biology School of MedicineKyungpook National UniversityDaeguRepublic of Korea Department of Biological Science Sungkyunkwan UniversitySuwonRepublic of Korea Department of Internal Medicine School of MedicineKyungpook National University HospitalDaeguRepublic of Korea Department of Biomedical Convergence Science and Technology School of ConvergenceKyungpook National UniversityDaeguRepublic of Korea

hepatocellular carcinoma(hCC)is the second most common cancer and the third leading cause of cancer-related death worldwide[1].Recently,hCC incidence and mortality rates have further increased due to changes in the global social environment and dietary habits[2].hCC is treated by surgical resection or combination chemotherapy,but the overall survival rate of hCC patients has not improved,and the recurrence rate is still h.g. due to strong invasiveness and resistance to chemotherapy[3].

关键词： chemotherapy mortality cancer

glucose-mediated mitochondrial reprogramming by cholesterol export at TM4SF5-enriched mitochondria-lysosome contact sites

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Cancer Communications 2024年第1期44卷 47-75页

作者： Ji Eon kim So-Young Park Chulhwan Kwak Yoonji Lee Dae-geun Song Jae Woo Jung haesong Lee Eun-Ae shin Yangie Pinanga Kyung-hee Pyo Eun hae Lee Wonsik kim Soyeon kim Chang-Duck Jun Jeanho Yun Sun Choi hyun-Woo Rhee Kwang-hyeon Liu Jung Weon Lee Department of Pharmacy College of PharmacySeoul National UniversitySeoulRepublic of Korea Research Institute of Pharmaceutical Sciences College of PharmacySeoul National UniversitySeoulRepublic of Korea BK21 FOUR Community-Based Intelligent novel Drug Discovery Education Unit College of Pharmacy and Research Institute of Pharmaceutical SciencesKyungpook National UniversityDaeguRepublic of Korea Department of Chemistry Seoul National UniversitySeoulRepublic of Korea College of Pharmacy Chung-Ang UniversitySeoulRepublic of Korea natural Product Informatics Research Center Korea Institute of Science and Technology(KIST)Gangneung-siGangwon-doRepublic of Korea School of Life Sciences Gwangju Institute of Science and Technology(GIST)GwangjuRepublic of Korea Department of Biochemistry College of MedicineDong-A UniversityBusanRepublic of Korea global AI Drug Discovery Center College of Pharmacy and Graduate School of Pharmaceutical SciencesEwha Womans UniversitySeoulRepublic of Korea Interdisciplinary Program in genetic Engineering Seoul National UniversitySeoulRepublic of Korea

Background:Transmembrane 4 L six family member 5(TM4SF5)translocates subcellularly and functions metabolically,although it is unclear how intracellu-lar TM4SF5 translocation is linked to metabolic *** is thus of interests to understand how the traffic dynamics of TM4SF5 to subcellular endosomal membranes are correlated to regulatory roles of ***:here,we explored the metabolic significance of TM4SF5 localization at mitochondria-lysosome contact sites(MLCSs),using in vitro cells and in vivo animal systems,via approaches by immunofluorescence,proximity labelling based proteomics analysis,organelle reconstitution ***:Upon extracellular glucose repletion following depletion,TM4SF5 became enriched at MLCSs via an interaction between mitochondrial FK506-binding protein 8(FKBP8)and lysosomal *** labeling showed molecular clustering of phospho-dynamic-related protein I(DRP1)and certain mitoph.g. receptors at TM4SF5-enriched MLCSs,leading to mitochondrial fis-sion and ***4SF5 bound nPC intracellular cholesterol transporter 1(nPC1)and free cholesterol,and mediated export of lysosomal cholesterol to mitochondria,leading to impaired oxidative phosphorylation but intact tri-carboxylic acid(TCA)cycle andβ-*** mouse models,hepatocyte Tm4sf5 promoted mitoph.g. and cholesterol transport to mitochondria,both with positive relations to liver ***:Our findings suggested that TM4SF5-enriched MLCSs regu-late glucose catabolism by facilitating cholesterol export for mitochondrial reprogramming,presumably while hepatocellular carcinogenesis,recapitulating aspects for hepatocellular carcinoma metabolism with mitochondrial repro-gramming to support biomolecule synthesis in addition to glycolytic energetics.

关键词： cholesterol fluorescent imaging glucose catabolism hepatocellular carcinogenesis mem-brane contact sites mitochondria function mitoph.g. oxidative phosphorylation protein-protein interaction tetraspanin