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Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

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neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： Carina hromada Patrick heimel Markus Kerbl Lászlógál Sylvia nürnberger Barbara Schaedl James Ferguson nicole Swiadek Xavier Monforte Johannes C.heinzel Antal nógrádi Andreas h.Teuschl-Woller David hercher Department Life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian Cluster for Tissue Regeneration ViennaAustria Ludwig Boltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University Clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tngCs). however, the use of tngCs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tngC would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tngCs and compared the various features of these improved silk^(+) tngCs with the tubes without holes(silk^(–) tngCs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tngCs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly h.g.er number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tngCs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tngCs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tngCs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

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Effect of Reactivity of Quick Lime on the Properties of hydrated Lime Sorbent for SO_2 Removal

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Journal of Materials Science & Technology 2009年第3期25卷 329-332页

作者： h.g. sh.n h. Kim Y.n. Kim h.S. Lee Department of Materials Science and Engineering Seoul National University Material Analysis Team Korea Testing Laboratory School of Materials Science and Engineering Pusan National University

The hydration of quick lime and the sulfation of hydrated lime were carried out for verification of relationship between the reactivity of quick lime and the properties of hydrated lime as a sorbent. The effect of reactivity of quick lime was investigated with the change of calcination temperature and time. Results obtained showed that the temperature rise during the hydration of quick limes varied from 31 to 69℃ with the variation of calcination temperature and time. The specific surface area and the sulfation ability of hydrated lime prepared by hydration of quick lime showed a proportional relationship with the reactivity of quick lime. The hydrated lime which was prepared by hydration of quick lime calcined at 1100℃ had the h.g.est reactivity and showed 41.53 m^2/g of the specific surface area, 0.16 cm^3/g of the pore volume and 87% of the removal efficiency for SO2 removal,

关键词： Reactivity Quick lime hydrated lime Calcination hydration Sorbent

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Sorption of certain lanthanides by kieselguhr loaded with Cyanex 572 from sulfate medium

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Journal of Rare Earths 2020年第3期38卷 299-305页

作者： sh.sh.Emam M.S.gasser n.E.El-hefny W.h.Mahmoud h.F.Aly hot Laboratories Centre Atomic Energy AuthorityCairo 13759Egypt Department of Chemistry Faculty of ScienceAin Shams UniversityCairoEgypt

Kieselguhr for chromatography was loaded with Cyanex 572 extractant and characterized using X-ray diffraction(XRF),scanning electron microscopy(SEM),Fourier transform infra-red(FT-IR),and thermal *** of some heavy lanthanides together with yttrium by the prepared kieselguhr/Cy-572 sorbent was investigated by batch experiment in terms of initial metal ions concentrations,volume to solid mass ratio(V/m),sulfuric acid concentration as well as *** sorption equilibrium of Cy-572 loaded kieselguhr was satisfactorily explained by the pseudo second-order kinetic model and Langmuir isotherm ***,the values of thermodynamic parameters △g°,△h°,and △S°at25℃of the studied metal ions show that the process is spontaneous and endothermic in nature.2.0 mol/L hnO3 is promising to desorb these metal ions.

关键词： Sorption Cyanex 572 Lanthanides Kieselguhr Sulfate medium Rare earths

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Comparative studies on Y(Ⅲ)and Dy(Ⅲ)extraction from hydrochloric and nitric acids by Cyanex 572 as a novel extractant

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Journal of Rare Earths 2018年第12期36卷 1342-1350页

作者： n.E.El-hefny M.S.gasser sh.sh.Emam W.h.Mahmoud h.F.Aly hot Laboratories Centre Atomic Energy Authority Faculty of Science Ain Shams University

Extraction of Y(III) and Dy(III) from hydrochloric and nitric acids by Cy-572 in kerosene was studied. The factors affecting the extraction were separately investigated. The stoichiometry of the extracted species was deduced on the basis of slope analysis method. Evaluation of extraction equilibrium and stripping investigation was studied as well as saponification effect of Cy-572. The composition of the extracted metal species in the organic phase was found to be [MA·(hA)] for Y(III) or Dy(III) in both media.1.0 mol/L hCI is the best stripping agent for each metal ion from the studied acidic media in one *** Cy-572 does not exhibit any selectivity towards the extraction of Y(III) or Dy(III) from both hCI and hnOsolutions. Based on the obtained results, the data were compared and the separation feasibility between lanthanides and Y(III) in the two media was discussed.

关键词： Extraction Cyanex-572 Yttrium Lanthanides Separation factor Saponification

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Experimental and numerical study on plasma nitriding of AISI P20 mold steel

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International Journal of Minerals,Metallurgy and Materials 2016年第9期23卷 1065-1075页

作者： n.nayebpashaee h.Vafaeenezhad sh.Kheirandish M.Soltanieh Materials Processing Simulation Laboratory(MPS-LAB) School of Materials and Metallurgical EngineeringIran University of Science and Technology(IUST) School of Materials and Metallurgical Engineering Iran University of Science and Technology(IUST)

In this study, plasma nitriding was used to fabricate a hard protective layer on AISI P20 steel, at three process temperatures（450℃, 500℃, and 550℃） and over a range of time periods（2.5, 5, 7.5, and 10 h）, and at a fixed gas n2：h2 ratio of 75vol%：25vol%. The morphology of samples was studied using optical microscopy and scanning electron microscopy, and the formed phase of each sample was determined by X-ray diffraction. The elemental depth profile was measured by energy dispersive X-ray spectroscopy, wavelength dispersive spectroscopy, and glow dispersive spectroscopy. The hardness profile of the samples was identified, and the microhardness profile from the surface to the sample center was recorded. The results show that ε-nitride is the dominant species after carrying out plasma nitriding in all strategies and that the plasma nitriding process improves the hardness up to more than three times. It is found that as the time and temperature of the process increase, the hardness and hardness depth of the diffusion zone considerably increase. Furthermore, artificial neural networks were used to predict the effects of operational parameters on the mechanical properties of plastic mold steel. The plasma temperature, running time of imposition, and target distance to the sample surface were all used as network inputs; Vickers hardness measurements were given as the output of the model. The model accurately reproduced the experimental outcomes under different operational conditions; therefore, it can be used in the effective simulation of the plasma nitriding process in AISI P20 steel.

关键词： tool steel plasma nitriding sputtering neural networks

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Leveraging ROTI map derived from Indonesian gnSS receiver network for advancing study of Equatorial Plasma Bubble in Southeast/East Asia

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Earth and Planetary Physics 2025年第1期9卷 101-116页

作者： Prayitno Abadi Ihsan n.Muafiry Teguh n.Pratama Angga Y.Putra Suraina gatot h.Pramono Sidik T.Wibowo Febrylian F.Chabibi Umar A.Ahmad Wildan P.Tresna Asnawi Research Center for Climate and Atmosphere Indonesian National Research and Innovation Agency(BRIN)BandungIndonesia School of Electrical Engineering Telkom UniversityBandungIndonesia Directorate of Laboratory Management Facilities and Science and Technology Park Indonesian National Research and Innovation Agency(BRIN)PontianakIndonesia geophysics Laboratory Master Program in PhysicsUniversitas Gadjah Mada(UGM)YogyakartaIndonesia Research Center for Space Indonesian National Research and Innovation Agency(BRIN)BandungIndonesia Indonesian geospatial Information Agency(BIg) JakartaIndonesia Research Center for Photonics Indonesian National Research and Innovation Agency(BRIN)Tangerang SelatanIndonesia Department of Earth and Planetary Sciences Hokkaido UniversitySapporoJapan

This paper h.g.lights the crucial role of Indonesia’s gnSS receiver network in advancing Equatorial Plasma Bubble(EPB)studies in Southeast and East Asia,as ionospheric irregularities within EPB can disrupt gnSS signals and degrade positioning *** by the Indonesian geospatial Information Agency(BIg),the Indonesia Continuously Operating Reference Station(Ina-CORS)network comprises over 300 gnSS receivers spanning equatorial to southern low-latitude ***-CORS is uniquely situated to monitor EPB generation,zonal drift,and dissipation across Southeast *** provide a practical tool for EPB research,by sharing two-dimensional rate of Total Electron Content(TEC)change index(ROTI)derived from this *** generate ROTI maps with a 10-minute resolution,and samples from May 2024 are publicly available for further scientific *** preliminary findings from the ROTI maps of Ina-CORS are ***,the Ina-CORS ROTI maps reveal that the irregularities within a broader EPB structure persist longer,increasing the potential for these irregularities to migrate farther ***,we demonstrate that combined ROTI maps from Ina-CORS and gnSS receivers in East Asia and Australia can be used to monitor the development of ionospheric irregularities in Southeast and East *** have demonstrated the combined ROTI maps to capture the development of ionospheric irregularities in the Southeast/East Asian sector during the g5 geomagnetic Storm on May 11,*** observed simultaneous ionospheric irregularities in Japan and Australia,respectively propagating northwestward and southwestward,before midnight,whereas Southeast Asia’s equatorial and low-latitude regions exhibited irregularities *** sharing ROTI maps from Indonesia and integrating them with regional gnSS networks,researchers can conduct comprehensive EPB studies,enhancing the understanding of EPB behavior across Southeast and East Asia and contributing significantly to ionosphe

关键词： Equatorial Plasma Bubble(EPB) gnSS receivers’network Indonesia Continuously Operating Reference Station(Ina-CORS) ionospheric map Rate of TEC change index(ROTI)map

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Effects of Charge Inheritance on h.g. Zn-Al Based Alloy

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Journal of Materials Science & Technology 1995年第2期11卷 153-156页

作者： gEng, h MA, JJ YAng, sh sh.ndong Polytechnic Univ Jinan China

The effects of several kinds of charges on microstructure and mechanical properties of ZA27 zinc alloy have been studied. Experimental results show that a certain amount of the mechining charge, granular charge and remelting charge treated in suitable way can increase greatly the mechanical properties of ZA27 alloy. It is thought that the charges possess microstructure inheritance to ZA27 alloy, so cause the property changes according to the viewpoints of casting alloy inheritance.

关键词： Zinc alloys

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Sliding Wear Behavior of a grey Cast Iron Surface Remelted by TIg

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Journal of Materials Science & Technology 2009年第5期25卷 622-628页

作者： h.Mohamadzadeh h.Saghafian sh.Kheirandish Department of Metallurgy and Materials Engineering Iran University of Science and TechnologyTehranIran

The sliding wear behavior of a grey cast iron surface remelted by tungsten inert gas （TIg） was studied and compared with the unremelted one in the current work. To evaluate the wear behavior a Pin-on-Disk wear test machine was used. Pins which were prepared from the samples with the remelted layers of different thicknesses of 1.2, 1.8, 2.5 and 3 turn were worn on an AISID3 steel counterface having a hardness of 63hRC under the applied loads of 54, 76 and gg n at a constant sliding velocity of 0.45 m/s. Scanning electron microscopy （SEM） equipped with energy dispersive X-ray analysis （EDS） and X-ray diffraction （XRD） techniques were used to characterize worn surface and subsurface and also wear debris obtained from the wear tests under different test conditions. Results showed that surface remelted grey cast iron have better wear properties for all applied normal loads in comparison with unremelted ones. Microscopic studies on the worn surfaces and subsurfaces of samples revealed that dominant wear mechanism for surface remelted samples was mild oxidative, while it was severe for unremelted samples. Increasing remelted layer thickness and then forming grosser microstructure lead to a decline of wear properties, whereas lower thickness of remelted layer with finer microstructure due to having h.g.er cooling rate through remelting process can withstand better against wear.

关键词： grey cast Iron Surface remelted Tungsten inert gas (TIg) Wear

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Dry Sliding Oxidative Wear in Plain Carbon Dual Phase Steel

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Journal of Iron and Steel Research International 2007年第4期14卷 43-48页

作者： V Abouei h Saghafian sh Kheirandish Department of Metallurgy and Materials Engineering Iran University of Science and TechnologyNarmak 16844TehranIran

To investigate the tribological potential of the dual phase （DP） steel as a wear resistant material, the wear and the friction characteristics of this steel, which consists of hard martensite islands embedded in a ductile ferrite matrix, have been investigated and compared with those observed in plain carbon hardened （h） steel that has the same carbon content of 0.2%. Dry sliding wear tests have been carried out using a pin-on-disk wear testing machine at different normal loads of 21.3 n, 28. 5 n, 35.7 n, and 42.6 n and at a constant sliding velocity of 1.20 m/s. The analysis of surface and wear debris of samples showed that the wear mechanism was mainly mild oxidative. The friction and the wear rate of the h steel and the DP Steel have been explained with respect to the microstructure and the wear mechanism.

关键词： dual phase steel wear microstructure heat treatment

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Evaluation of Four Coals for Blast Furnace Pulverized Coal Injection

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Journal of Iron and Steel Research International 2010年第3期17卷 8-12,20页

作者： sh Raygan h Abdizadeh A Eskandari Rizi School of Metallurgy and Materials Engineering University of Tehran

One of the effective methods of reducing coke consumption is pulverized coal injection. The most important problems encountered in this method are reduced permeability, unburned and h.g. ash content. To select the best coal for injection, suitable tests can be used. Therefore, experiments such as proximate and ultimate analysis, Rock- Eval and combustion tests were performed on four kinds of coals from different mines, including Sarakhs, Sangrood, Karmozd, and Tabas. The results of proximate and ultimate analysis indicated that although the sulfur content and ash content of selected coals were a little h.g., they were suitable for coal injection. The results of combustion experiments and Rock-Eval tests showed that Karmozd coal was the best one to be injected into blast furnace. The result indicated that the mixing of coals could improve the combustion properties of pulverized coals.

关键词： pulverized coal blast furnace non-coking coal

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