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Editorial for th. Special Issue on Emerging Tech.ology and Advanced Application of Nondestructive Detection for Power Equipment

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Ch.nese j.urnal of Electrical Engineering 2024年第1期10卷 1-2页

作者： Li j. Mei h. Li S. Tianj.n University China Tsingh.a Sh.nzh.n International Graduate Sch.ol China Lanzh.u j.aotong University China

Th. rapid development of clean and renewable energy tech.ologies represented by wind and solar energy,as well as th. continuous growth.of load demand,h.ve put forward h.gh.r requirements for th. safe operation of th. power *** performance of power equipment based on traditional dielectric materials is often limited by various defects generated during molding,transportation,assembly,and operation,wh.ch.cannot meet th. reliability requirements of power systems in th. new *** detection is an essential tech.ical meth.d in industrial development,wh.ch.can detect and evaluate th. defect and damage status of in-service equipment,key components,and materials with.ut damaging th. obj.ct.

关键词： service Application operation

A h.drodynamic modelling of wave-activated bodies for wavelet marine regions

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CLEAN ENERGY 2024年第2期8卷 35-47页

作者： Peh. j. S. Muh.eldeen, Moh.mmed W. Sh.aib, N. h. UCSI Univ Fac Engn Technol & Built Environm Mech Engn Dept Kuala Lumpur 56000 Malaysia MTC Engineer Sdn Bh. Shah Alam Selangor Malaysia

Recently, most wave energy research.h.s targeted sea areas with.h.gh.power density under extreme wave conditions for deployment. Th.s trend often leads to h.gh.r energy costs for wave power plants. h.wever, many marine areas with.low power density, ch.racterized by wavelet conditions and less destructive forces th.n extreme wave conditions, remain underexplored. Th.refore, th.s study aimed to propose a wave-activated body model for sea regions with.wavelet conditions. Th. wave-activated body design process encompassed site selection, parameter determination, geometry design, comparison and performance evaluation using th. ANSYS (R) AQWA model. Th. results indicated th.t th. proposed device ach.eved th. desired h.ave motion, with.an amplitude range of 1.2 to -2.5 m, validating its potential for deployment in marine regions with.wavelet conditions. Notably, wh.le th. proposed design is optimized for wavelet conditions, it was found to h.ve potential limitations in extreme wave environments. Th.s observation emph.sizes th. ch.llenge of formulating a generalized design suitable for both.conditions. Consequently, it is pivotal for wave-activated body designs to be customized based on th. specific ocean conditions th.y target, underscoring th. need for specialized designs of wave energy converters th.t consider th. unique wave ch.racteristics of th.ir deployment sites. A wave-activated body is designed for energy generation in ocean regions with.wavelet conditions. h.drodynamic modelling is carried out for two locations with.different wave ch.racteristics to determine th. optimum conditions for deployment. Graph.cal Abstract

关键词： wave energy converter South.Ch.na sea renewable and sustainable energy wavelet ANSYS AQWA h.drodynamic wave-activated bodies ENERGY IMPACT

Ch.nese Expert Consensus on th. Diagnosis and Treatment of Adult Dermatomyositis (2022)#

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International j.urnal of Dermatology and Venereology 2024年第3期7卷 163-173页

作者： Cao h. Ch.n A.-j. Cui Y. Deng D.-Q. Gao X.-h. h. Y.-L. Kang X.-j. j.n h.-Z. Li C.-X. Li F. Li h.-j. Liao W.-j. Liu X.-M. Lu Q.-j. Lu Y. Pan M. Pan W.-h. Sh. X.-M. Sun Q. Tang K.-Y. Tao j. Wang Y. Xiao T. Zh.ng F.-R. Zh.ng h.-L. Department of Dermatology Ruijin Hospital Affiliated Shanghai Jiao Tong University School of Medicine Shanghai 200025 China Department of Dermatology First Affiliated Hospital of Chongqing Medical University Chongqing 400042 China Department of Dermatology China-Japan Friendship Hospital Beijing 100029 China Department of Dermatology The Second Affiliated Hospital of Kunming Medical University Yunnan Kunming 650101 China Department of Dermatology The First Hospital of China Medical University Liaoning Shenyang 110001 China Department of Dermatology Beijing Chaoyang Hospital Affiliated to Capital Medical University Beijing 100020 China Department of Dermatology and Venereology People's Hospital of Xinjiang Uygur Autonomous Region Xinjiang Uygur Autonomous Region Urumqi 830001 China Department of Dermatology State Key Laboratory of Complex Severe and Rare Diseases Peking Union Medical College Hospital Chinese Academy of Medical Science Peking Union Medical College Beijing 100730 China Department of Dermatology First Medical Center PLA General Hospital Beijing 100853 China Department of Dermatology Hainan Hospital of PLA General Hospital Hainan Sanya 572013 China Department of Dermatology Xijing Hospital Air Force Medical University Shaanxi Xi'an 710032 China Department of Dermatology Huazhong University of Science and Technology Union Shenzhen Hospital Guangdong Shenzhen 518052 China h.spital for Skin Diseases Institute of Dermatology Chinese Academy of Medical Sciences Peking Union Medical College Jiangsu Nanjing 210042 China Department of Dermatology Jiangsu Province Hospital The First Affiliated Hospital Nanjing Medical University Jiangsu Nanjing 210029 China Department of Dermatology Shanghai Changzheng Hospital Second Affiliated Hospital of Naval Medical University Shanghai 200003 China Department of Rh.umatology China-Japan Friendship Hospital Beijing 100029 China Department of Dermatology Qilu Hospital of Shandong Universit

Dermatomyositis, an idiopath.c inflammatory myopath., is ch.racterized by distinctive skin manifestations, proximal muscle weakness, and multiple organ involvement and can be accompanied by malignancies. To provide a reference for dermatologists and clinicians in oth.r relevant fields of clinical practice, experts from th. Dermatology Branch.of th. Ch.na International Exch.nge and Promotion Association for Medical and h.alth.Care and th. National Clinical Research.Center for Dermatologic and Immunologic Diseases developed th.s consensus on th. diagnosis and treatment of adult dermatomyositis using Ch.nese and international literature and expert advice. © 2024 Wolters Kluwer h.alth. All righ.s reserved.

关键词： adult clinical protocols dermatomyositis diagnosis expert consensus treatment

“Yin-Yang ph.losoph.” for th. design of anticancer drug delivery nanoparticles

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Biomaterials Translational 2024年第2期5卷 144-156页

作者： Ai Y. Tian Y. Qiao j. Wang C. Li h. Sch.ol of Lifesciences Shanghai University Shanghai China

Understanding th. in vivo transport process provides guidelines for designing ideal nanoparticles (NPs) with.h.gh.r efficacy and fewer off-target effects. Many factors, such.as particle size, morph.logy, surface potential, structural stability, and etc., may influence th. delivering process of NPs due to th. existence of various ph.siological barriers with.n th. body. h.rein, we summarise th. distinct influences of NP ph.sicoch.mical properties on th. four consecutive in vivo transport steps: (1) navigating with.bloodstream with.n blood vessels, (2) transport across vasculature walls into tumour tissues, (3) intratumoural transport th.ough.th. interstitial space, and (4) cellular uptake & intracellular delivery by cancerous cells. We found th.t th. ph.losoph. beh.nd th. current consensus for NP design h.s certain similarities to th. “Yin-Yang” th.ory in traditional Ch.nese culture. Almost all ph.sicoch.mical properties, regardless of big or small sizes, long or sh.rt length. positive or negative zeta potentials, are double-edged swords. Th. balance of potential benefits and side effects, drug selectivity and accessibility sh.uld be fully considered wh.n optimising particle design, similar to th. “Yin-Yang h.rmony”. Th.s paper presents a compreh.nsive review of th. advancements in NPs research. focusing on th.ir distinct features in tumour targeting, drug delivery, and cell uptake. Additionally, it deliberates on future developmental trends and potential obstacles, th.reby aiming to uncover th. ways th.se ch.racteristics influence th. NPs’ biological activity and provide th.oretical guidance for th. targeted delivery of NPs. © 2024, Ch.nese Medical Multimedia Press Co Ltd. All righ.s reserved.

关键词： in vivo drug delivery nanoparticle design on-demand drug release targeting strategy “Yin-Yang h.rmony”

Bile acids,gut microbiota,and th.rapeutic insigh.s in h.patocellular carcinoma

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Cancer Biology & Medicine 2024年第2期21卷 144-162页

作者： Yang Song h.rry Ch.lau Xiang Zh.ng j.n Yu Institute of Digestive Disease and Department of Medicine and Th.rapeutics State Key Laboratory of Digestive DiseaseLi Ka Shing Institute of Health SciencesCUHK Shenzhen Research InstituteThe Chinese University of Hong KongHong KongChina Department of Gastroenterology Zhongshan Hospital Xiamen UniversityXiamen 361004China

h.patocellular carcinoma(h.C)is a prevalent and aggressive liver *** interplay between bile acids(BAs)and th. gut microbiota h.s emerged as a critical factor in h.C development and *** normal conditions,BA metabolism is tigh.ly regulated th.ough.a bidirectional interplay between gut microorganisms and *** gut microbiota plays a critical role in BA metabolism,and BAs are endogenous signaling molecules th.t h.lp maintain liver and intestinal *** note,dysbiotic ch.nges in th. gut microbiota during path.genesis and cancer development can disrupt BA h.meostasis,th.reby leading to liver inflammation and fibrosis,and ultimately contributing to h.C ***,understanding th. intricate interplay between BAs and th. gut microbiota is crucial for elucidating th. mech.nisms underlying *** th.s review,we compreh.nsively explore th. roles and functions of BA metabolism,with.a focus on th. interactions between BAs and gut microorganisms in ***,th.rapeutic strategies targeting BA metabolism and th. gut microbiota are discussed,including th. use of BA agonists/antagonists,probiotic/prebiotic and dietary interventions,fecal microbiota transplantation,and engineered *** summary,understanding th. complex BA-microbiota crosstalk can provide valuable insigh.s into h.C development and facilitate th. development of innovative th.rapeutic approach.s for liver malignancy.

关键词： Bile acid gut microbiota h.patocellular carcinoma th.rapeutics microbiota modulation

Net effect of air pollution controls on h.alth.risk in th. Beij.ng-Tianj.n-h.bei region during th. 2022 winter Olympics and Paralympics

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j.urnal of Environmental Sciences 2024年第1期135卷 560-569页

作者： Ch.ngqing Lin Peter K.K.Louie Alexis K.h.lau j.mmy C.h.Fung Zibing Yuan Mingh.i Tao Xuguo Zh.ng Md.Sh.kh.oat h.ssain Ch.ngcai Li Xiang Qian Lao Division of Environment and Sustainability The Hong Kong University of Science and TechnologyHong KongChina Environmental Protection Department Hong Kong Government SARHong KongChina Department of Civil and Environmental Engineering The Hong Kong University of Science and TechnologyHong KongChina Guangdong-h.ngkong-Macao j.int Laboratory of Collaborative Innovation for Environmental Quality The Hong Kong University of Science and TechnologyHong KongChina Department of Math.matics The Hong Kong University of Science and TechnologyHong KongChina Sch.ol of Environment and Energy South China University of TechnologyGuangzhou 510006China h.bei Key Laboratory of Critical Zone Evolution School of Geography and Information EngineeringChina University of GeosciencesWuhan 430074China Department of Public h.alth.and Informatics Jahangirnagar UniversityDhaka 1342Bangladesh Department of Atmosph.ric and Oceanic Sciences School of PhysicsPeking UniversityBeijing 100871China j.ckey Club Sch.ol of Public h.alth.and Primary Care The Chinese University of Hong KongHong KongChina

Due to th. non-linearity in ozone(O_(3))formation,reducing th. emission of nitrogen oxides(NO_(x))may increase O_(3) *** th. counteractive O_(3) response to NO_(x) reduction,overall impact of air pollution controls can be ambiguous wh.n th. assessments focus on th. ch.nges in pollutant *** th.s study,a risk-based meth.d was used to gauge th. net effect of air pollution controls on mortality risk in th. Beij.ng–Tianj.n–h.bei(BTh.region during th. 2022 Winter Olympics and Paralympics(WOP).Th.s mega-event presents a unique opportunity to investigate th. efficacy of deep cuts in pollutant *** sh.w th.t O_(3) concentrations greatly increased as nitrogen dioxide(NO_(2))concentrations decreased in th. *** to th. active ph.toch.mical formations,O_(3) became th. dominant pollutant th.t affected h.man h.alth.during th. *** th. substantial O_(3) increases,th. h.alth.benefits of NO_(2) reductions overwh.lmed th. adverse h.alth.effects of O_(3) increases in most regions of th. BTh.at 81 out of 112 stations).After considering th. impacts of particulate matter,th. integrated h.alth.risk of air pollution mixtures declined almost everywh.re in th. *** results underscore th. great necessity of ch.nging th. assessment paradigm of pollution control from using concentration-based meth.ds to using risk-based *** with.th. carbon neutrality policy,stringent control of NO_(x)emission from combustion sources is a promising way to ach.eve synergistic control solutions for air pollution and climate ch.nge.

关键词： Ozone Nitrogen dioxide h.alth.risk Carbon neutrality Mega-events

A novel meth.d for th. green utilization of waste fried oil

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Particuology 2024年第1期84卷 1-11页

作者： Gan Ch.ng Mengni Zh.ng Yang Lu Yanh.i Zh.ng Bin Lin Ee Von lau College of Ch.mistry and Ch.mical Engineering Henan Polytechnic UniversityJiaozuo454003China h.nan Key Laboratory for Green and Efficient Mining&Compreh.nsive Utilization of Mineral Resources Henan Polytechnic UniversityJiaozuo454003China Collaborative Innovation Center of Coal Work Safety and Clean h.gh.Efficiency Utilization Henan Polytechnic UniversityJiaozuo454003China Sch.ol of Engineering Monash University MalaysiaSubang JayaSelangor47500Malaysia

Waste fried oil was studied to prepare th.ee different types of detergent such.as soap,liquid soap and soap powder via saponification *** preparation conditions of soap base were optimized by orth.gonal *** specific preparation processes included waste fried oil treatment,orange peel extract preparation,saponification,demoulding and *** sh.wed th.t th. optimal con-ditions for saponification were as follows:ratio of pure waste fried oil to coconut oil=6∶4,alkali liquor(NaOh.mass fraction 30%,saponification temperature 70℃,orange peel extract concentration 15%.Th. mature soap was th.n used to make liquid soap and soap powder by surfactant(sodium dodecylbenzene sulfonate,coconut dieth.nol amide)addition,followed by *** prepared detergent conforms to th. production standard of strong decontamination ability,possesses stable performance,is gentle to skin and non-toxic.

关键词： Waste fried oil Detergent Saponification Decolorization

Th. quasi-Gramian solution of a non-commutative extension of th. h.gh.r-order nonlinear Sch.?dinger equation

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Communications in Th.oretical Ph.sics 2024年第3期76卷 51-61页

作者： h.W A Riaz j.Lin Department of Ph.sics Zhejiang Normal UniversityJinhua 321004China

Th. nonlinear Sch.?dinger(NLS)equation,wh.ch.incorporates h.gh.r-order dispersive terms,is widely employed in th. th.oretical analysis of various ph.sical *** th.s study,we explore th. non-commutative extension of th. h.gh.r-order NLS *** treat real or complex-valued functions,such.as g_(1)=g_(1)(x,t)and g_(2)=g_(2)(x,t)as non-commutative,and employ th. Lax pair associated with.th. evolution equation,as in th. commutation *** derive th. quasi-Gramian solution of th. system by employing a binary Darboux *** soliton solutions are presented explicitly with.n th. framework of *** visually understand th. dynamics and solutions in th. given example,we also provide simulations illustrating th. associated ***,th. solution can be used to study th. stability of plane waves and to understand th. generation of periodic patterns with.n th. context of modulational instability.

关键词： integrable systems Darboux transformation solitons

Abalone sh.ll-derived Mg-doped mesoporous h.droxyapatite microsph.re drug delivery system loaded with.icariin for inducing apoptosis of osteosarcoma cells

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Biomaterials Translational 2024年第2期5卷 185-196页

作者： Liu K. Ch.ng M. h.ang h. Yu h. Zh.o S. Zh.u j. Tie D. Wang j. Pan P. Ch.n j. Marine College Shandong University Shandong Province Weihai China State Key Laboratory of Mineral Processing Beijing China College of Biological Science and Tech.ology Fuzhou University Fujian Province Fuzhou China

h.droxyapatite (h.P) porous microsph.res with.very h.gh.specific surface area and drug loading capacity, as well as excellent biocompatibility, h.ve been widely used in tumour th.rapy. Mg2+ is considered to be a key factor in bone regeneration, acting as an active agent to stimulate bone and cartilage formation, and is effective in accelerating cell migration and promoting angiogenesis, wh.ch.is essential for bone tissue repair, anti-cancer, and anti-infection. In th.s study, abalone sh.lls from a variety of sources were used as raw materials, and Mg2+-doped abalone sh.ll-derived mesoporous h.P microsph.res (Mg-h.P) were prepared by h.droth.rmal synth.sis as Mg2+/icariin smart dual delivery system (ICA-Mg-h.P, IMh.). With.increasing of Mg2+ doping, th. surface morph.logy of h.P microsph.res varied from collapsed macroporous to mesoporous to smooth.and non-porous, wh.ch.may be due to Mg2+ substitution or coordination in th. h.P lattice. At 30% Mg2+ doping, th. Mg-h.P microsph.res sh.wed a more h.mogeneous mesoporous morph.logy with.a h.gh.specific surface area (186.06 m2/g). Th. IMh. microsph.res sh.wed h.gh.drug loading (7.69%) and encapsulation rate (83.29%), sustained Mg2+ release for more th.n 27 days, sustained and stable release of icariin for 60 h.urs, and good responsiveness to ph.(ph.6.4 > ph.5.6). In addition, th. IMh. delivery system stimulated th. rapid proliferation of bone marrow mesench.mal stem cells and induced apoptosis in MG63 cells by blocking th. G2 ph.se cycle of osteosarcoma cells and stimulating th. h.gh.expression of apoptotic genes (Bcl-2, caspase-3,-8,-9). Th.s suggests th.t th. abalone sh.ll-based IMh. may h.ve potential applications in drug delivery and tumour th.rapy. © 2024, Ch.nese Medical Multimedia Press Co Ltd. All righ.s reserved.

关键词： abalone sh.ll drug delivery h.droxyapatite microsph.res magnesium doping osteosarcoma