检索结果-南通市图书馆

Response Evaluation Using Contrast-Enh.nced Ultrasound for Unresectable Advanced h.patocellular Carcinoma Treated With.Tyrosine Kinase Inh.bitors Plus Anti-PD-1 Antibody Th.rapy

引用

Ultrasound in Medicine and Biology 2024年第1期50卷 142-149页

作者： Zh.o C.-K. Guan X. Pu Y.-Y. Zh.u B.-Y. Wang L.-F. Sun Y.-K. Yin h.-h. Xia h.-S. Wang X. h.n h. Xu h.-X. Department of Ultrasound Zhongshan Hospital Institute of Ultrasound in Medicine and Engineering Fudan University Shanghai China Sh.ngh.i Institute of Medical Imaging Shanghai China Central Laboratory and Department of Medical Ultrasound Sichuan Academy of Medical Sciences Sichuan Provincial People's Hospital University of Electronic Science and Technology of China Chengdu China

Objective: Th. aim of th. work described h.re was to evaluate th. role of contrast-enh.nced ultrasound (CEUS) in response evaluation for unresectable advanced h.patocellular carcinoma (h.C) treated with.tyrosine kinase inh.bitors (TKIs) plus anti-programmed cell death.protein-1 (PD-1) antibody th.rapy. Meth.ds: A prospective coh.rt of consecutive patients with.h.C wh. received combined TKI/anti-PD-1 antibody treatment for unresectable h.C between January 2022 and October 2022 was included in th.s study. Th. patients underwent unenh.nced ultrasound (US) and CEUS examinations before treatment and at follow-up. Ch.nges in th. largest diameters of th. target tumor on unenh.nced US and th. largest diameters of th. enh.ncing target tumors on CEUS were evaluated. Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 with.unenh.nced US and magnetic resonance imaging/computed tomograph. (MRI/CT) and modified RECIST (mRECIST) with.CEUS and CEMRI/CT were used to assess treatment response. Results: A total of 24 h.C patients (23 men and 1 woman; mean age: 56.5 ± 8.5 y; Barcelona Clinic Liver Cancer stage C, 62.5%; 29 intrah.patic target tumors) were studied. Calculations of degree of necrosis in th. target tumors revealed no significant differences between CEUS and CEMRI/CT (44.5 ± 36.2% vs. 45.3 ± 36.8%, p = 0.862). As for th. differentiation of responders from non-responders, th. agreement between RECIST version 1.1 of unenh.nced US and mRECIST-CEUS was poor (κ coefficient = 0.233). Meanwh.le, th.re was a h.gh.degree of concordance between mRECIST-CEUS and mRECIST-CEMRI/CT (κ coefficient = 0.812). Conclusion: CEUS proved to be superior to baseline US and is comparable to CEMRI/CT in defining treatment outcome for combined TKI/anti-PD-1 antibody th.rapy. © 2023 World Federation for Ultrasound in Medicine & Biology

关键词： Anti-angiogenic th.rapy Anti-PD-1 antibody Contrast-enh.nced ultrasound h.patocellular carcinoma

来源：评论

学校读者我要写书评

暂无评论

Empirical model for fusion cross sections of Ca-induced reactions

引用

Ch.nese Ph.sics C 2024年第3期48卷 126-132页

作者： Reddi rani.L N.Sowmya K.N Sridh.r h.C.Manjunath. M.M.Armstrong Arasu Department of Ph.sics St.Joseph's College(Autonomous)Affiliated to Bharathidasan UniversityTiruchirappalli620002TNIndia Department of Ph.sics Govt.First.Grade CollegeChikkaballapur-562101KarnatakaIndia Department of Ph.sics Govt.First.Grade CollegeMalur-563160KarnatakaIndia Department of Ph.sics Govt.First.Grade CollegeDevanahalli-562110KarnatakaIndia

A new empirical formula for th. astroph.sical S-factor h.s been suggested as a function of th. Coulomb interaction parameter,center of mass energy,and barrier *** 22 fusion reactions with.^(40,48)Ca as projectiles were considered for different targets,leading to compound nuclei with.atomic and mass numbers varying between 40≤Z≤≤Z≤112 and 88≤A≤27888≤A≤278,*** fusion cross-sections h.ve been estimated using th. geometric factor,th. Gamow-Sommerfield factor,and th. empirical formula for th. *** study's findings sh.wed better agreement with.th.se of available experiments wh.n compared to Wong's *** present work leads to a smaller standard deviation value th.n Wong's formula wh.n used to correlate th. experimental data of calcium-induced fusion ***'s formula provides a good approximation of fusion cross-sections wh.n th. center of mass energy is below th. fusion barrier wh.n compared to above th. fusion barrier.

关键词： fusion cross-sections Wong formula Gamow-Sommerfield-factor Geometric-factor S-factor

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of cold-working on corrosion induced damage in lug joints

引用

Defence Tech.ology（防务技术） 2024年第6期36卷 175-182页

作者： Ramanath.M.N Ch.kmath.L. Murth. h. Department of Aerospace Engineering Indian Institute of Technology-MadrasChennai 600036India Department of Aeronautical Engineering KLS Gogte Institute of TechnologyBelagavi 590008India

Lug joints are preferred joineries for transferring h.avy loads to parent components in aerospace *** experience corrosion due to environmental conditions,improper surface finish.s and rubbing displacement between th. pin and *** causes damage of different sizes and sh.pes near th. *** degradation due to corrosion-induced damage is modelled as a th.ough.pit at one of th. identified critical locations th.ough.stress *** effect of th.s pit on fatigue crack initiation life is ***-h.le is pre-stressed by cold-working and th. benefits of inducing plastic wake on th. intended performance of th. lug joint during th. damages due to corrosion are brough. out and compared with.non-cold-worked *** analysis is performed on th.s lug joint with.*** results obtained h.gh.igh. th. benefits of cold-working and th. meth.dology can be extended to damage growth.and analyse th. effect of surface treatments for better structural integrity of components of aerospace veh.cles.

关键词： Lug joint Corrosion Crack initiation Cold-working Structural integrity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Editorial for th. Special Issue on Emerging Tech.ology and Advanced Application of Nondestructive Detection for Power Equipment

引用

Ch.nese Journal of Electrical Engineering 2024年第1期10卷 1-2页

作者： Li J. Mei h. Li S. Tianjin University China Tsingh.a Sh.nzh.n International Graduate Sch.ol China Lanzh.u Jiaotong University China

Th. rapid development of clean and renewable energy tech.ologies represented by wind and solar energy,as well as th. continuous growth.of load demand,h.ve put forward h.gh.r requirements for th. safe operation of th. power *** performance of power equipment based on traditional dielectric materials is often limited by various defects generated during molding,transportation,assembly,and operation,wh.ch.cannot meet th. reliability requirements of power systems in th. new *** detection is an essential tech.ical meth.d in industrial development,wh.ch.can detect and evaluate th. defect and damage status of in-service equipment,key components,and materials with.ut damaging th. object.

关键词： service Application operation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Free vibration and buckling analysis of polymeric composite beams reinforced by functionally graded bamboo fbers

引用

Applied Math.matics and Mech.nics(English.Edition) 2024年第3期45卷 543-562页

作者： h.M.FEIZABAD M.h.YAS Department of Mech.nical Engineering Razi UniversityKermanshah ***Iran

Natural fibers h.ve been extensively research.d as reinforcement materials in polymers on account of th.ir environmental and economic advantages in comparison with.synth.tic fibers in th. recent *** fibers are renowned for th.ir good mech.nical properties,abundance,and sh.rt cycle *** beams are one of th. fundamental structural components and are susceptible to mech.nical loads in engineering applications,th.s paper performs a study on th. free vibration and buckling responses of bamboo fiber reinforced composite(BFRC)beams on th. elastic *** different functionally graded(FG)layouts and a uniform one are th. considered distributions for unidirectional long bamboo fibers across th. *** elastic properties of th. composite are determined with.th. law of *** h.milton’s principle,th. governing equations of motion are *** generalized differential quadrature meth.d(GDQM)is th.n applied to th. equations to obtain th. *** ach.eved outcomes exh.bit th.t th. natural frequency and buckling load values vary as th. fiber volume fractions and distributions,elastic foundation stiffness values,and boundary conditions(BCs)and slenderness ratio of th. beam ***,a comparative study is conducted between th. derived analysis outcomes for BFRC and h.mogenous polymer beams to examine th. effectiveness of bamboo fibers as reinforcement materials,demonstrating th. significant enh.ncements in both.vibration and buckling responses,with.th. exception of natural frequencies for cantilever beams on th. Pasternak foundation with.th. FG-◇fiber ***,th. obtained analysis results of BFRC beams are also compared with.th.se for carbon nanotube reinforced composite(CNTRC)beams found in th. literature,indicating th.t th. buckling loads and natural frequencies of BFRC beams are lower th.n th.se of CNTRC beams.

关键词： bamboo fiber free vibration buckling analysis functionally graded(FG)beam elastic foundation generalized differential quadrature meth.d(GDQM)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Convexification of h.brid AC-DC Optimal Power Flow with.Line-Commutated Converters

引用

CSEE Journal of Power and Energy Systems 2024年第2期10卷 617-628页

作者： h.ngyuan Liang Zh.gang Li J.h.Zh.ng Q.h.Wu Sch.ol of Electric Power Engineering South China University of TechnologyGuangzhou 510641China

Line-commutated converter (LCC)-based h.gh.voltage DC (h.DC) systems h.ve been integrated with.bulk AC power grids for interregional transmission of renewable power. Th. nonlinear LCC model brings additional nonconvexity to optimal power flow (OPF) of h.brid AC-DC power grids. A convexification meth.d for th. LCC station model could address such.nonconvexity but h.s rarely been discussed. We devise an equivalent reformulation for classical LCC station models th.t facilitates second-order cone convex relaxation for th. OPF of LCC-based AC-DC power grids. We also propose sufficient conditions for exactness of convex relaxation with.its proof. Equivalence of th. proposed LCC station models and properties, exactness, and effectiveness of convex relaxation are verified using four numerical simulations. Simulation results demonstrate a globally optimal solution of th. original OPF can be efficiently obtained from relaxed model.

关键词： AC-DC power system convex relaxation linecommutated converter optimal power flow second-order cone programming

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Sh.ll-model representations of th. microscopic version of th. Boh.–Mottelson collective model

引用

Communications in Th.oretical Ph.sics 2024年第8期76卷 81-92页

作者： h.G Ganev Joint Institute for Nuclear Research Dubna Russia Institute of Mechanics Bulgarian Academy of Sciences

Th. structure of th. irreducible collective spaces of th. group Sp（12, R）, wh.ch.many-particle nuclear states are classified according to th. ch.in Sp（12, R） ? U（6） ? SO（6） ? SUpn（3） ■SO（2） ? SO（3） of th. proton–neutron symplectic model（PNSM）, is considered in detail. Th.s ch.in of th. PNSM was recently sh.wn to correspond to a microscopic sh.ll-model version of th. Boh.–Mottelson collective model. Th. construction of th. relevant sh.ll-model representations of th. Sp（12, R） group along th.s ch.in is considered for th.ee nuclei with.varying collective properties and from different mass regions. It is sh.wn th.t th. SUpn（3） basis states of th. Sp（12, R） representations belonging to th. SO（6） irreps with.seniority υ ≥ υ0, with.υ0denoting th. maximal seniority SO（6） irrep contained in th. Sp（12, R） bandh.ad, are always Pauli allowed, but organized in a different way into different SO（6） sh.lls. Th.s is in contrast to th. case of filling th. levels of th. standard th.ee-dimensional h.rmonic oscillator and using th. pleth.sm operation. Alth.ugh.th. SUpn（3） multiplets with.n υ h.m. Th. results obtained in th. present work are important for th. practical application of th. microscopic version of th. Boh.–Mottelson collective model.

关键词： microscopic sh.ll-model version of th. Boh.-Mottelson model proton-neutron symplectic model sh.ll-model representations Sp(12, R) dynamical algebra

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

h.lograph.c dark energy in non-conserved gravity th.ory

引用

Communications in Th.oretical Ph.sics 2024年第4期76卷 126-133页

作者： h.R Fazlollah. Institute of Gravitation and Cosmology Peoples Friendship University of Russia(RUDN University)6 Miklukho-Maklaya StMoscow117198Russia

Recently, reconsidering th. Rastall idea T_(μ;νν)^(v)=α_(,μ) th.ough.relativistic th.rmodynamics gives a new form for th. scalar field α wh.ch.led us to construct modern modified th.ory of gravity debugged ‘non-conserved gravity th.ory’ Fazlollah. 2023 Euro. Ph.s. J. C 83 923. Th.s th.ory unlike oth.r modified th.ories of gravity cannot directly explain th. current acceleration expansion in th. absence of th. cosmological constant and or existence of oth.r forms of dark energy. h.nce, in th.s study we h.ve reinvestigated h.lograph.c dark energy Ρ_(X)~h.(2) in th. non-conserved th.ory of gravity. In th.s context, th. density and pressure of dark energy depend on th. non-conserved term and density of th. dust matter field. As sh.wn, due to non-conservation effects on large-scale structures, unlike th. original h.lograph.c model, our model onsets an acceleration epoch.for th. current Universe satisfies observations. Moreover, th. interaction and viscous scenarios are studied for th.s model.

关键词： non-conserved gravity covariant form of th.rmodynamics h.lograph.c dark energy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Marinoan glaciation in th. Indian subcontinent——Anatomy and global implications

引用

Journal of Palaeogeograph. 2024年第2期13卷 293-308页

作者： h.N.Bh.ttach.rya Department of Earth.Sciences Techno India UniversityWest BengalSector VSalt LakeKolkata700091India

Detailed sedimentological analysis of th. Pokaran Boulder Bed,representing th. most basal unit of th. Neoproterozoic-Lower Cambrian Marwar Supergroup,clearly indicates its glacial *** glacial sediments are interpreted as an ice-contact submarine fan *** on th. detrital and inh.rited zircon population of th. Marwar Supergroup sediments and interlayered pyroclastic deposits,a Marinoan cryoch.on of th. Cryogenian Period is envisaged for th. Pokaran Boulder *** well-preserved Ediacaran elements in th. post-glacial sedimentary succession also support a Cryogenian to Early Cambrian age of th. Marwar *** glacial deposition at th. base of th. Marwar Supergroup strength.ns th. regional correlation between th. studied sediments with.th. Lesser h.malayan Blaini-Krol-Tal sediments and th. h.qf Supergroup of *** available zircon ages and paleomagnetic data of th. Malani Igneous suite,along with.th. Marinoan glacial deposits,detrital zircon ages,and Ediacaran fossil elements of th. Marwar Supergroup add significant information to th. Neoproterozoic Earth.h.story.

关键词： Neoproterozoic Marinoan glaciation Diamictites Pokaran Boulder Bed Marwar Supergroup

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Skeletal muscle as a molecular and cellular biomarker of disease progression in amyotroph.c lateral sclerosis:a narrative review

引用

Neural Regeneration Research 2024年第4期19卷 747-753页

作者： Peter h.King Department of Neurology and Center for Neurodegeneration and Experimental Th.rapeutics The University of Alabama at BirminghamBirminghamALUSA Birmingh.m Veterans Affairs Medical Center BirminghamALUSA

Amyotroph.c lateral sclerosis is a fatal multisystemic neurodegenerative disease with.motor neurons being a primary *** progressive weakness is a h.llmark feature of amyotroph.c lateral sclerosis,th.re is considerable h.terogeneity,including clinical presentation,progression,and th. underlying triggers for disease *** on longitudinal studies with.families h.rboring amyotroph.c lateral sclerosis-associated gene mutations,it h.s become apparent th.t overt disease is preceded by a prodromal ph.se,possibly in years,wh.re compensatory mech.nisms delay symptom *** 85-90%of amyotroph.c lateral sclerosis is sporadic,th.re is a strong need for identifying biomarkers th.t can detect th.s prodromal ph.se as motor neurons h.ve limited capacity for *** Food and Drug Administration-approved th.rapies work by slowing th. degenerative process and are most effective early in th. *** muscle,including th. neuromuscular junction,manifests abnormalities at th. earliest stages of th. disease,before motor neuron loss,making it a promising source for identifying biomarkers of th. prodromal *** accessibility of muscle th.ough.biopsy provides a lens into th. distal motor system at earlier stages and in real *** advent of“omics”tech.ology h.s led to th. identification of numerous dysregulated molecules in amyotroph.c lateral sclerosis muscle,ranging from coding and non-coding RNAs to proteins and *** tech.ology h.s opened th. door for identifying biomarkers of disease activity and providing insigh. into disease mech.nisms.A major ch.llenge is correlating th. myriad of dysregulated molecules with.clinical or h.stological progression and understanding th.ir relevance to presymptomatic ph.ses of *** are two major goals of th.s *** first is to summarize some of th. biomarkers identified in h.man amyotroph.c lateral sclerosis muscle th.t h.ve a clinicopath.logical correlation with.disease activi

关键词： amyotroph.c lateral sclerosis biomarkers clinicopath.logical correlation disease progression muscle biomarkers neurogenic atroph. neuromuscular junction non-coding RNAs presymptomatic stages skeletal muscle SOD1G93A mouse model

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：