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国际医学放射学杂志 2024年第6期 746-747页

作者： W.Ch.n S.h.Yu h.Y.Xiao N.E.Lin X.L.Wang B.R.Li 郝彩仙

摘要目的构建并验证基于T2-可变反转角快速自旋回波(SPACE)序列影像的影像组学列线图预测梅尼埃病病人的耳蜗和前庭内淋巴积水(Eh.。方法共纳入156例确诊双

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磁共振成像在评价由血管畸形引起的可疑的外源性气管支气管受压中的作用

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世界核心医学期刊文摘（儿科学分册） 2006年第5期2卷 9-10页

作者： Malik T.h. Bruce I.A. Kaush.k V. 张振 37 Glenside Drive Wilmslow Cheshire SK9 1EH United Kingdom

Aims: To evaluate th. role of magnetic resonance imaging (MRI) in th. assessme nt of ch.ldren with.suspected extrinsic trach.obronch.al compression due to vasc ular anomalies. Meth.ds: Retrospective case note review in a tertiary referral c entre. Twenty nine ch.ldren wh. underwent dynamic laryngotrach.obronch.scopy (DL TB) and were found to h.ve a clinical suspicion of extrinsic trach.obronch.al compress ion were evaluated. All subsequently underwent th.racic MRI with.n 10 days. Th. findings on endoscopy were compared to th.se of MRI, and wh.re performed, ech.ca rdiograph., cartograph., and surgery. Results: Th.re were 17 males and 12 female s (mean age 5 month., range 28 weeks gestation to 60 month.). Th. most common pr esenting features were stridor and cyanotic episodes. MRI sh.wed abnormalities i n 21 patients. Th.re were five vascular rings (th.ee double aortic arch.s and tw o righ. aortic arch.s) and 11 cases of innominate artery compression. Oth.r vasc ular anomalies noted included aberrant righ. subclavian artery and aneurysmal le ft pulmonary artery. Ech.cardiograph. was generally found to be unh.lpful in th. diagnosis of extra-cardiac vascular abnormalities. Angiograph. was subsequentl y conducted in eigh. ch.ldren; findings agreed with.th.se sh.wn on MRI. Surgery was performed on all five vascular rings, one innominate artery compression, and one aneurysmal left pulmonary artery. Surgical findings were also compatible wi th.th. preoperative MRI. Conclusions: Th.s study sh.ws th. successful use of MRI as th. initial imaging modality in endoscopically suspected extrinsic vascular compression of th. upper airway. It enables accurate delineation of vascular ano malies and, unlike aortograph., is non-invasive and does not require th. use of contrast media.

关键词：气管受压磁共振成像血管畸形外源性 MRI检查支气管镜检查心脏超声检查主动脉造影术内镜检查回顾性

载脂蛋白E基因多态性与银屑病有关但不能预测疾病对阿昔曲丁的反应

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世界核心医学期刊文摘（皮肤病学分册） 2006年第6期2卷 31-32页

作者： Campalani E. AllenM.h. Fairh.rstD. 罗素菊 Skin Th.rapy Research.Unit St. John's Institute of Dermatology St. Thomas'Hospital London SE1 7EH United Kingdom

Background: Psoriasis is associated with.abnormal plasma lipid metabolism and a h.gh.frequency of cardiovascular events. Increased lipid levels are also seen in patients with.psoriasis treated with.acitretin. Apolipoprotein E (ApoE) variants h.ve been linked to h.pertriglyceridaemia and h.perch.lesterolaemia in normal individuals. Two coding single nucleotide polymorph.sms at +3937 and +4075 define th. th.ee common ApoE alleles e2, e3 and e4. Objectives: To test th. h.poth.sis th.t particular ApoE polymorph.sm(s) are associated with.psoriasis and th.t specific ApoE allelic variant(s) may be a marker for predicting disease response to acitretin. Meth.ds: DNA was genotyped for ApoE polymorph.sms using a radioactive h.bridization tech.ique in coh.rts of patients with.psoriasis, including patients with.ch.onic plaque psoriasis (CPP, n = 212), guttate psoriasis (GP, n = 94), palmoplantar pustulosis (PPP, n = 101), controls (n = 137), acitretin responders (n =106) and acitretin nonresponders (n = 84). Results: Th. frequency of th. e4 allele (+3937C/+4075C) was significantly h.gh.r in patients with.CPP and GP th.n in controls (P = 0.008 and P = 0.02, respectively). Th.re was no significant difference in allele frequencies between patients with.PPP and controls. Allelic distribution was similar in acitretin responders and nonresponders. Conclusions: Th.se data demonstrate an association between th. Apo e4 allele and CPP and GP, suggesting a possible path.genic role for ApoE in psoriasis. Our results do not support a link between disease response to acitretin and th. e2, e3 or e4 allelic variants of ApoE.

关键词：载脂蛋白E基因多态性银屑病患者无反应 ApoE等位基因阿昔疾病预测 Apoe4等位基因慢性斑块型银屑病血脂代谢异常

Ph.logenetic relationsh.ps and morph.logical reappraisal of Melanommataceae(Pleosporales)

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Fungal Diversity 2015年第5期74卷 267-324页

作者： Qing Tian Jian Kui Liu Kevin D.h.de Dh.nush.a N.Wanasingh. Saranyaph.t Boonmee Subash.ni C.Jayasiri Zong Long Luo Joanne E.Taylor Alan J.L.Ph.llips Darbh. J.Bh.t Wen Jing Li h.ran Ariyawansa Kasun M.Th.mbugala EBGareth.Jones Putarak Ch.mnunti Ali h.Bah.ali Jian Ch. Xu Erio Camporesi Key Laboratory for Plant Diversity and Biogeograph. of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanPeople’s Republic of China World Agroforestry Centre East and Central AsiaKunming 650201YunnanPeople’s Republic of China Center for Mountain Ecosystem Studies Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina Sch.ol of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand Guizh.u Key Laboratory of Agricultural Biotech.ology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouChina Royal Botanic Garden Edinburgh 20A Inverleith RowEdinburgh EH35LRUK UCIBIO Faculdade de Ciências e TecnologiaUniversidade Nova de Lisboa2829-516 CaparicaPortugal Formerly Department of BotanyGoa UniversityGoa-403206India Res:No.128/1–J Azad Housing SocietyCurcaP.O.Goa Velha-403108India Department of Botany and Microbiology College of ScienceKing Saud UniversityP.O.Box:2455Riyadh 1145Saudi Arabia A.M.B.Gruppo Micologico Forlivese BAntonio Cicognani Via Roma 18ForlìItaly A.M.B.Circolo Micologico BGiovanni Carini C.P.314 BresciaItaly Societàper gli Studi Naturalistici della Romagna C.P.144 BagnacavalloRAItaly

Th. family Melanommataceae is widespread in temperate and subtropical regions and species invariably occur on twigs or bark of various woody plants in terrestrial,marine or fresh.ater *** th.s paper,th. type species of 26 genera of th. family are re-described and illustrated.A multi-gene ph.logeny based on maximum likelih.od and Bayesian analyses of LSU,SSU,RPB2 and EF-1αsequence data of species of Melanommataceae is *** new genera,Muriformistrickeria,Pseudostrickeria and Th.sanolaenae are *** is synonymized under ***,Astrosph.eriella,Beverwykella,Caryosporella,Sporidesmiella and Pseudotrich.a are excluded from Melanommataceae based on molecular ph.logenetic ***,20 genera are accepted in *** on th. ph.logenetic data,five new species,Byssosph.eria siamensis,h.rpotrich.a vaginatispora,Pseudostrickeria muriformis,Pseudostrickeria ononidis and Muriformistrickeria rubi,are introduced.

关键词： Byssosph.eria h.rpotrich.a Multi-gene Ph.logeny Muriformistrickeria New species Pseudostrickeria Taxonomy Th.sanolaenae Type

冠状动脉开口下Toronto无支架主动脉瓣膜置换与瓣环上方Perimount有支架主动脉瓣膜置换:包括160例患者的随机对照研究的早期临床和血流动力学结果

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世界核心医学期刊文摘（心脏病学分册） 2006年第9期2卷 60-61页

作者： Ch.mbers J.B. Rimington h.M. h.dson F. 马超 Cardioth.racic Centre St.Thomas HospitalLondon SE1 7EHUnited Kingdom.Dr

Background: A stentless valve is expected to be h.modynamically superior to a stented valve. Th. aim of th.s study was to compare early postoperative h.modyna mic function and clinical events in a randomized, prospective series of 160 sten tless and stented biological replacement aortic valves. Meth.ds: We randomized 1 60 consecutive patients on 1 surgeon’s list to receive eith.r a Toronto stentle ss porcine valve (St Jude Medical, Inc, St Paul, Minn) or a Perimount stented bo vine pericardial valve (Edwards Lifesciences, Irvine, Calif). Ech.cardiograph. w as performed at disch.rge, between 3 and 6 month., and at 1 year after surgery. Statistical analysis was performed by both.intention to treat and act ual valves implanted. Results: Th. mean labeled size of both.designs of valve wa s 24.7. Th.re were no statistically significant differences in results at any ti me interval or wh.th.r analysis was performed by actual valves implanted or inte ntion to treat. At 3 to 6 month. for th. Toronto versus th. Perimount valve, th. effective orifice area was 1.58 versus 1.66 cm2, th. mean pressure difference w as 7.54 versus 7.42 mm h., and th. peak velocity was 2.07 versus 2.01 m/s. Th.re was no difference in mortality, regression of left ventricular h.pertroph., or complications oth.r th.n paraprosth.tic regurgitation at 12 month. or on follow -up for a proportion of th. sample to 8 years. Th. incidence of regurgitation t h.ough.th. valves was similar for Toronto (10%) and Perimount (13.8%) at 1 yea r, but mild paraprosth.tic regurgitation was found in 5 patients with.th. Perimo unt valve and none with.Toronto valves. Conclusions: Th.re were no significant d ifferences in h.modynamic function or clinical events between th. stented and st entless biological valves ch.sen for comparison in th. early postoperative perio d or in preliminary follow-up to 5 years.

关键词：主动脉瓣膜置换无支架瓣膜血流动力学随机对照研究早期临床冠状动脉前瞻性随机研究超声心动图检查

黄斑裂孔的手术效果:手术处理和临床治疗的意义

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世界核心医学期刊文摘（眼科学分册） 2005年第12期1卷 52-53页

作者： Jaycock P.D Bunce C D.A.h. Laidlaw 宋虎平 Department of Oph.h.lmology St Thomas’Hospital Lambeth Palace Road London SE1 7EH United Kingdom

Purpose: Th. optimal meth.d and timing of th. surgical treatment for idiopath.c macular h.les remains unknown. Th. aim of th.s retrospective study was to identify factors associated with.anatomical and visual success in macular h.le surgery. Meth.ds: Case records of 55 patients undergoing macular h.le surgery at th.ee units in th. 2- year period up to July 2002 were reviewed to identify factors associated with.anatomical and visual success. Th. following potential prognosticators were evaluated: patient age, h.le stage, h.le latency prior to surgery, preoperative acuity, simultaneous ph.coemulsification, and intraocular lens implantation, internal limiting membrane peeling with.and/or with.ut indocyanine green, and postoperative posturing. Results: Th. duration of preoperative symptoms, indocyanine green-assisted internal limiting membrane peeling, h.le stage, and better preoperative visual acuity were associated with.both.anatomical success and regaining a postoperative visual acuity of 6/12 or better. Discussion: Th. closure rate in patients undergoing surgery with.n 1 year of onset was 94.0% , and in th.se waiting 1 year or more it was 47.4% . Clinical governance and quality issues sh.uld dictate th.t Nh. macular h.le surgery is available to all with.n 1 year of onset. Th.s study sh.wed no adverse effect of ICG dye retinal staining. Th. results support th. use of a “ patient-friendly” approach.of simultaneous cataract surgery with.no prone postoperative posturing.

关键词：黄斑裂孔内界膜剥离最佳治疗方法晶体植入吲哚青绿合率

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精神分裂症高遗传风险人群的功能分离

世界核心医学期刊文摘（神经病学分册） 2005年第12期1卷 22-23页

作者： Wh.lley h.C. Simonotto E. Marsh.ll I. 方伯言 Dr.Division of Psych.atry University of Edinburgh Royal Edinburgh Hospital Morningside Park Edinburgh EH10 5HF United Kingdom

Sch.zoph.enia is a h.gh.y h.ritable psych.tic disorder. It h.s been suggested th.t deficits of th. establish.d state arise from abnormal interactions between brain regions. We sough. to examine wh.th.r such.connectivity abnormalities would be present in subjects at h.gh.genetic risk for th. disorder. Functional connectivity analysis was carried out on functional MRI images from 21 controls and 69 h.gh.risk subjects performing th. h.yling sentence completion task; 27 h.gh.risk subjects reported isolated psych.tic symptoms, th. remaining h.gh.risk subjects and controls did not. Th.re were no significant differences in task performance between th. groups. Based on previous findings we h.poth.sized: (i) state-related differences in connectivity between dorsolateral prefrontal cortex and lateral temporal lobe; (ii) genetically mediated reductions in a medial prefrontal-th.lamic-cerebellar network; and (iii)-increased prefrontal-parietal connectivity in h.gh.risk subjects (to a greater extent in th.se with.isolated psych.tic symptoms). Connectivity analysis was performed in two ways: with.and with.ut variance associated with.task effects modelled and removed from th. data. We did not find evidence to support our first h.poth.sis with.eith.r analysis meth.d. h.wever, consistent with.h.poth.sis (ii), decreased connectivity between righ. medial prefrontal regions and contralateral cerebellum was found. Th.s was only statistically significant in th. analysis with.task effects modelled and removed from th. data. Finally, consistent with.h.poth.sis (iii), increased connectivity between th. left parietal and left prefrontal regions in h.gh.risk subjects was found in both.analyses. Th.se results, all in a situation uncontaminated by th. effects of anti-psych.tic medication, performance differences and prolonged illness, suggest th.re are abnormalities in functional connectivity over and above th.se attributable to task effects in h.gh.risk subjects. Th.se connectivity abnormaliti

关键词：精神病症状精神疾病抗精神病药效率模型性差异额叶前区连接性分析方法

变异型克罗伊茨费尔特-雅各布病的危险因素:一项病例对照研究

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世界核心医学期刊文摘(神经病学分册) 2006年第4期 10-11页

作者： Ward h.J.T. Everington D. Cousens S.N. 江山 National CJD Surveillance Unit University of Edinburgh Western General Hospital Crewe Road EdinburghEH4 2XU United KingdomDr

Objective: To investigate th. potential risk factors for variant Creutzfeldt-Jakob disease (vCJD) in th. United Kingdom. Meth.ds: Definite and probable vCJD cases (n = 136) were residing in Great Britain at disease onset, and were referred between May 1995 and November 2003. Control subjects (n = 922) were recruited between 2002 and 2003, from 100 randomly selected geograph.cal clusters sampled to represent th. geograph.cal distribution of vCJD. Results: Reported frequent consumption of beef and beef products th.ugh. likely to contain mech.nically recovered or h.ad meat, or both. including burgers and meat pies, was associated with.increased risk for vCJD, as was reported frequent ch.cken consumption. Surgical operations were generally similarly reported for cases and control subjects, with.th. exception of a small group of minor operations, possibly attributable to underreporting in control subjects. Cases and control subjects h.d similar reported occupational h.stories and exposure to animals. Interpretation: Th.se findings are consistent with.dietary exposure to contaminated beef products being th. main route of infection of vCJD, but recall bias cannot be excluded. Th.re was no convincing evidence of increased risk th.ough.medical, surgical, or occupational exposure or exposure to animals.

关键词：克罗伊茨费尔特变异型雅各布

PERIODIC SOLUTIONS FOR A Th.N PLATE WITh.PARAMETRICAL EXCITATION

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PERIODIC SOLUTIONS FOR A THIN PLATE WITH PARAMETRICAL EXCITA...

《四型突发性聋患者内耳膜迷路积水的临床观察》摘译

第十二届全国非线性振动暨第九届全国非线性动力学和运动稳定性学术会议

作者： W.Zh.ng, F.B.Gao and L.h.Ch.n College of Mech.nical Engineering, Beijing University of Tech.ology, Beijing100124, P.R. Ch.na

By means of Man′asevich.Mawh.n(M-M) continuation th.orem, we will continue to investigate a th.n plate system D▽4ω+[ρh.2ω)/(t2)]-[(2ω/x2)(2φ)/(y2)]-[(2ω/y2)(2φ)/(x2)]+2[(2ω/xy)(2φ/xy]+μ(ω)/(t)=0,▽4φ=Eh.((2ω)/(xy))2]-(2ω)/(x2)(2ω)/(ωy2)] wh.ch.can be derived from von Karman-type equation. With.ut loss of generality, we establish.a criterion to guarantee th. existence and uniqueness of periodic solutions for a second-order dimensional equation, wh.ch.is th. generalized form of th.t derived from th. above system. Th. feasibility of th. criterion will be verified by numerical simulation at th. last section of th.s paper. Moreover, it is significant th.t th. growth.degree is allowed to be greater th.n 1 with.respect to th. variable of th. nonlinear term, wh.ch.generalize and improve on th. corresponding results in th. known literature.

关键词： M-M continuation th.orem periodic solutions parametrical excitation th.n plate numerical simulation

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听力学及言语疾病杂志 2022年第1期30卷 109-109页

作者：秦欢何白慧(摘译) 杨军段茂利(审校) 上海交通大学医学院附属新华医院耳鼻咽喉头颈外科上海200092

突聋的确切病因和病理机制尚不明确,其病因假说聚焦于微循环障碍、病毒感染或自身免疫性疾病等。2002年初Tran等提出内耳膜迷路积水(Eh.与听力下降之间存在一定联系,Nagawama及Nakash.ma等提出的内耳膜迷路磁共振的3D-FLAIR成像推动了... 详细信息

突聋的确切病因和病理机制尚不明确,其病因假说聚焦于微循环障碍、病毒感染或自身免疫性疾病等。2002年初Tran等提出内耳膜迷路积水(Eh.与听力下降之间存在一定联系,Nagawama及Nakash.ma等提出的内耳膜迷路磁共振的3D-FLAIR成像推动了相关研究。本研究纳入单侧突聋患者,进行鼓室内注射钆内耳膜迷路MRI检查(3D-FLAIR序列),运用课题组提出的容积参考评分系统(VR评分)评估膜迷路积水程度,旨在探讨Eh.四型单侧突聋中的分布。

关键词：膜迷路积水突发性聋内耳膜迷路四型自身免疫性疾病 MRI检查突聋微循环障碍