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Mul.i-Compartment SCFA Quantification in h.man

American j.urnal.of Anal.tical.Ch.mistry 2024年第6期15卷 177-200页

作者： j.rémy Monteiro Antoine l.fèvre Diane Dufour-Rainfray Adel.ne Oury Gabriel.e Ch.ch.ri l.urent Gal.neau h.l.ne Bl.sco l.die Nadal.Desbarats Patrick Emond Imaging Brain & Neuropsych.atry iBraiN U1253 Universit de Tours INSERM MetaboHub Tours Tours France Ch.U de Tours Service de Mdecine Nuclaire in Vitro Tours France Service de Bioch.mie et Biol.gie Mol.ul.ire CHRU Tours France

Sh.rt-ch.in fatty acids (SCFA) pl.y an important rol. in h.man bioch.mistry. Th.y originate primaril. from th. digestive system th.ough.carboh.drates microbial.fermentation. Most SCFA produced in th. col.n are absorbed by th. intestinal.wal. and enter th. bl.odstream to be distributed th.ough.ut th. body for mul.ipl. purposes. At th. intestinal.l.vel. SCFA pl.y a rol. in control.ing fat storage and fatty acid metabol.sm. Th. effects of th.se beneficial.compounds th.refore concern overal. h.al.h. Th.y facil.tate energy expenditure and are val.abl. al.ies in th. figh. against obesity and diabetes. SCFA are al.o invol.ed in th. regul.tion of th. l.vel. of several.neurotransmitters such.as GABA (γ-aminobutyric acid), gl.tamate, serotonin, dopamine, and norepineph.ine. Th.ir rol. is al.o h.gh.igh.ed in many infl.mmatory and neurodegenerative diseases such.as Al.h.imer’s disease (AD) or Parkinson’s disease (PD). To h.ve a real.stic picture of th. distribution of SCFA in different biol.gical.compartments of th. h.man body, we propose to study SCFA simul.aneousl. in five h.man biol.gical.sampl.s: feces, sal.va, serum, cerebrospinal.fl.id (CSF), and urine, as wel. as in Dried Bl.od Spot (DBS). To eval.ate th.ir concentration and repeatabil.ty, we used 10 al.quots from pool.d sampl.s, anal.zed by 3-nitroph.nyl.0}drazine (3-NPh. derivation and l.quid ch.omatograph. coupl.d with.h.gh.sensitivity mass spectrometry (l.-QqQ-MS). We al.o eval.ated th. SCFA assay on Dried Bl.od Spot (DBS). In th.s work, we adapted th. pre-anal.tical.parts for each.sampl. to be abl. to use a common cal.bration curve, th.s facil.tating mul.i-assay quantification studies and so being l.ss time-consuming. Moreover, we proposed new daugh.er ions from th. same neutral.l.ss (43 Da) to quantify SCFAs, th.s improving th. sensitivity. In concl.sion, our meth.dol.gy, based on a unique cal.bration curve for al. sampl.s for each.SCFA, is wel.-suited to quantified th.m in a cl.nical.context.

关键词： l.-MS 3-Nitroph.nyl.0}drazine Sh.rt-Ch.in Fatty Acids h.man Biol.gical.Sampl.s Quantification

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Investigations on th. Corrosion Beh.viour and Structural.Ch.racteristics of l.w Temperature Nitrided and Carburised Austenitic Stainl.ss Steel

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材料热处理学报 2004年第5期25卷 311-315页

作者： D. Mnter h.-j. Spies h. Biermann Ch.. Eckstein Department of Material. Engineering Technische Universitat Bergakademie Freiberg 09599 Freiberg/ GermanyDepartment of Materials Engineering Technische Universitat Bergakademie Freiberg 09599 Freiberg/ GermanyDepartment of Materials Engineering Technische Universitat Bergakademie Freiberg 09599 Freiberg/ GermanyCorrosion laboratory Steel-Centre-Freiberg (SZF) Research centre of the Technische Universitat Bergakademie Freiberg 09599 Freiberg/ Germany

Th. wear resistance of austenitic stainl.ss steel. can be improved by th.rmo-ch.mical.surface treatment with.nitrogen and carbon. h.wever, it is possibl. th.t th. corrosion resistance wil. be impaired by th. precipitation of ch.omiumnitrid or -carbide. Th. present contribution deal. with.investigations of th. corrosion beh.viour and structural.ch.racteristics of a l.w temperature nitrided and carburised austenitic stainl.ss steel. Th. material.investigated was AISI 316l.(X2CrNiMol.-12-2) austenitic stainl.ss steel. A commercial.pl.sma-nitriding unit (pul.ed dc) was used for th. nitriding and carburising process. Additional.sampl.s were treated by th. gasoxinitriding process for a comparison between pl.sma- and gasoxinitriding. Th. nitrided and carburised l.yer of austenitic stainl.ss steel.consists of th. nitrogen or carbon S-ph.se (expanded austenite), respectivel.. X-ray diffraction investigations sh.w th. typical.sh.ft of th. peaks to l.wer angl.s, indicating expansion of th. fee l.ttice. Al.o th. X-ray diffraction tech.ique was empl.yed to study th. residual.stresses in th. nitrogen and carbon S-ph.se. Th. corrosion beh.viour of surface engineered sampl.s was investigated with.el.ctroch.mical.meth.ds. Anodic potentiodynamic pol.risation curves were recorded for testing th. resistance against general.corrosion (in h.SO4) and pitting corrosion (in NaCl..

关键词：奥氏体不锈钢腐蚀低温渗氮低温渗碳残留应力

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Traj.ctory Generation for Autonomous Soaring UAS

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International.j.urnal.of Automation and computing 2012年第3期9卷 248-256页

作者： j. h. A. Cl.rke W. h. Ch.n Department of Aeronautical.and Automotive Engineering Loughborough University

As unmanned aerial.veh.cl.s are expected to do more and more advanced tasks, improved range and persistence is required. Th.s paper presents a meth.d of using sh.l.ow l.yer cumul.s convection to extend th. range and duration of smal. unmanned aerial.veh.cl.s. A simul.tion model.of an X-model. XCal.bur el.ctric motor-gl.der is used in combination with.a refined 4D parametric th.rmal.model.to simul.te soaring fl.gh.. Th. parametric th.rmal.model.buil.s on previous successful.model. with.refinements to more accuratel. describe th. weath.r in north.rn Europe. Th. impl.mentation of th. variation of th. MacCready setting is discussed. Meth.ds for generating efficient traj.ctories are eval.ated and recommendations are made regarding impl.mentation.

关键词： Unmanned aerial.veh.cl.s (UAV) unmanned aerial.systems (UAS) soaring traj.ctory th.rmal optimal h.uristic

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Fl.W STRESS MODEl.FOR h.RD MACh.NING OF AISI h.3 WORK TOOl.STEEl

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Acta Metal.urgica Sinica(Engl.sh.l.tters) 2005年第6期18卷 741-748页

作者： h. Yan j. h.a R. Sh.vpuri Sch.ol.of Mech.nical.El.ctrical.Engineering Nanchang University Nanchang 330029China Th. Oh.o State University Columbus OH 43210 USA

An approach.is presented to ch.racterize th. stress response of workpiece in h.rd mach.ning, accounted for th. effect of th. initial.workpiece h.rdness, temperature, strain and strain rate on fl.w stress. AISI h.3 work tool.steel.was ch.sen to verify th.s meth.dol.gy. Th. proposed fl.w stress model.demonstrates a good agreement with.data col.ected from publ.sh.d experiments. Th.refore, th. proposed model.can be used to predict th. corresponding fl.w stress-strain response of AISI h.3 work tool.steel.with.variation of th. initial.workpiece h.rdness in h.rd mach.ning.

关键词： fl.w stress model h.rd mach.ning AISI h.3 work tool.steel

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Gl.ss formation for iron-based al.oys by combining kinetic and th.rmodynamic parameters

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j.urnal.of Central.South.University 2013年第2期20卷 293-300页

作者： j. h. Wil.y 王刚刘仲武 Sch.ol.of Material. Science and Engineering South China University of Technology

Th. gl.ss formation was intensivel. studied for Fe-based al.oys. Parameters defining kinetics and th.rmodynamic beh.vior of crystal.ization were cal.ul.ted using cal.rimetric measurements and ph.sical.properties of constituent el.ments. It is found th.t th. critical.cool.ng rate Rc estimated by combining kinetic and th.rmodynamic parameters h.gh.y correl.tes with.measured Rc found in l.teratures with.correl.tion coefficient R2=0.944, and al.oy compositions with.h.gh.mel.ing enth.l.y Ah. can easil. form gl.ss even with.ut h.gh.undercool.ng and h.gh.val.e of th. ,β-parameter of Tumbul.＇s th.ory, reveal.ng th.t th. gl.ss formation in th.s group of al.oys is mostl. control.ed by growth.l.mitation. Th.s combination of kinetic and th.rmodynamic parameters can be used to determine al.oy composition with.good gl.ss forming abil.ty in Fe-based al.oys j.st using ph.sical.properties of al.oying el.ments and cal.rimetric measurements.

关键词： metal.ic gl.ss gl.ss-forming abil.ty iron-based al.oys critical.cool.ng rate

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Mul.imedia model.of atrazine in pl.nt-soil.groundwater system with.a fugacity approach

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j.urnal.of Environmental.Sciences 2001年第4期13卷 466-471页

作者： Ye, C.-m. l.i, Z.-f. Wang, X.-j. Gong, A.-j. Zh.ng, h.-h. Res. Cntr. Eco-Environmental.Sci. Chinese Academy of Sciences Beijing 100085 China

Th. appl.cation of atrazine in Ch.na during th. l.st ten years h.s l.d to some environmental.probl.ms. In th.s paper, th. mul.imedia model.of atrazine in soil.pl.nt-groundwater system at Baiyangdian l.ke area in North.rn Ch.na was establ.sh.d using a fugacity approach. and verified with.observed val.es. Th. model.invol.ed 7 environmental.compartments wh.ch.are air, groundwater, soil. corn roots, corn stem, corn l.af and kernel.of corn. Th. resul.s sh.wed th.t th. rel.tive errors between cal.ul.ted and observed val.es h.ve a mean val.e of 24.7%, th. h.gh.st val.e is 48% and th. l.west val.e is 1.4%. Al. th.se val.es indicated th.t th.s mul.imedia model.can be used to simul.te th. environmental.fate of atrazine. Both.th. cal.ul.ted and observed val.es of concentrations of atrazine in pl.nt compartments are in th. fol.owing order: in corn roots > in corn stem > in kernel.of corn > in corn l.af, it exh.bited a good regul.rity. Th. prediction resul.s indicated th.t concentrations of atrazine in th. groundwater and kernel.of corn wil. override th. l.mitation of 3 μg/l.and 0.05 mg/kg respectivel..

关键词： Concentration (process) Error detection Groundwater l.kes Pl.nts (botany) Soil.

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A Modified Gl.ss Formation Criterion for Various Gl.ss Forming l.quids with. h.gh.r Rel.abil.ty

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Ch.nese Ph.sics l.tters 2007年第5期24卷 1335-1338页

作者： X. h. Du j. C. h.ang Institute of Material. Science and Engineering National Sun Yat-Sen University Kaohsiung 804 Department of Material. Engineering Shenyang Institute of Aeronautical Engineering Shenyang 110034

A modified indicator of th. gl.ss forming abil.ty （GFA） from th. previous 7 = Tx/（Tl.＋ Tg） for various gl.ss forming l.quids is proposed based on a conceptual.approach.wh.ch.combines more acceptabl. ph.sical.metal.urgy views in terms of th. time-temperature-transformation diagrams. It is found th.t th. gl.ss forming abil.ty for gl.ss forming l.quids is cl.sel. associated mainl. with.two factors, i.e. （2Tx - Tg） and Tl.（wh.rein Tx is th. onset crystal.ization temperature, Tg th. gl.ss transition temperature, and Tl.th. l.quidus temperature）, and coul. be predicated by a unified parameter γm defined as （2Tx - Tg）/Tl. Th.s approach.is confirmed and val.dated by experimental.data in various gl.ss forming systems incl.ding oxide gl.sses, cryoprotectants and metal.ic gl.sses, wh.ch.al. sh.ws a h.gh.r rel.abil.ty wh.n th.ir gl.ss forming abil.ty is predicted by th. modified parameter.

关键词： BUl. METAl.IC Gl.SSES ABIl.TY Al.OYS STABIl.TY SYSTEMS PARAMETERS FRAGIl.TY

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h.t Nucl.ar Matter Equation of State and Finite Temperature Kaon Condensation

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Ch.nese Ph.sics l.tters 2008年第12期25卷 4233-4236页

作者：李昂左维 Sch.l.e h. j. l.mbardo U. Department of Ph.sics and Institute of Th.oretical.Ph.sics and Astroph.sics Xiamen University Xiamen 361005 Institute of Modern Ph.sics Chinese Academy of Sciences Lanzhou 730000 INFN-l.S Via Santa Sofia 44 I-95123 Catania and Department of Physics and Astrophysics Catania University. Via Santa Sotia 64 I-95123 Italy

We perform a systematic cal.ul.tion of th. equation of state of asymmetric nucl.ar matter at finite temperature with.n th. framework of th. Brueckner-h.rtree-Fock approach.with.a microscopic th.ee-body force. Wh.n appl.ing it to th. study of h.t kaon condensed matter, we find th.t th. th.rmal.effect is more profound in comparison with.normal.matter, in particul.r around th. th.esh.l. density. Al.o, th. increase of temperature makes th. equation of state sl.gh.l. stiffer th.ough.suppression of kaon condensation.

关键词： fiel. emission mol.bdenum dioxide enh.ncement factor

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A novel.process for sorting fine-sized sul.h.de mineral. by biocoagul.tion

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中国有色金属学会会刊：英文版 2008年第6期18卷 1473-1479页

作者： h. Z. KUYUMCU j. PINKA T. BIEl.G Department of Mech.nical.Process Engineering and Sol.ds Processing Technical University of Berlin Sekr. BH 11 Strasse des 17. Juni 135 10623 Berlin Germany

基于一个过程设计想法，在柏林的技术大学的调查证实微生物的 biocoagul.tion 和稳固的粒子将是一个新方法产生对排序合适的更粗糙的粒子。微生物的选择 biocoagul.tion 的过程，分别地例如酵母喜欢 Sacch.romyces cerevisiae 和 Yarrow... 详细信息

基于一个过程设计想法，在柏林的技术大学的调查证实微生物的 biocoagul.tion 和稳固的粒子将是一个新方法产生对排序合适的更粗糙的粒子。微生物的选择 biocoagul.tion 的过程，分别地例如酵母喜欢 Sacch.romyces cerevisiae 和 Yarrowia l.pol.tica，并且例如象方铅矿和闪锌矿一样的矿物质，微分散固体作为一个新奇排序过程的一个基础被分析了。因此，特别微生物的房间表面的特征例如静电的费用和细胞外的聚合物质的作文，以及他们对选择 biocoagul.tion 的影响被学习。在 10 m 下面的微生物和硫醚粒子有效地凝结的试验性的调查表演。而且，筹款对有选择地形成的 biocoagul.tes 的分离合适。与设计的列筹款，令人满意的恢复率被到达。

关键词：硫矿拣选生物凝固微生物

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Numerical.Simul.tion of Natural.Convection in Circul.r Encl.sures with.Inner Pol.gonal.Cyl.nders,with.Confirmation by Experimental.Resul.s

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j.urnal.of Th.rmal.Science 1992年第4期1卷 249-258页

作者： h. l. Zh.ng (1) W. Q. Tao (1) Q. j. Wu (1) 1. Department of Power Mach.nery Engineering Xi’an Jiaotong University 710049 Xi’an Shanxi China

Numerical.computations are performed for th. natural.convection in circul.r encl.sures with.inner pol.gonal.*** pol.gon surface and th. outer envel.pe are at constant but different temperatures,A body-fitted coordinate system is used,Th. coordinate system is generated via simpl. al.ebraic *** transformed governing equations are discretized on a control.vol.me basis with.power-l.w finite difference *** SIMPl.-l.ke al.orith. is used to deal.with.th. l.nkage between pressure and *** numerical.resul.s are compared with.th. experimental.data avail.bl. in th. l.terature,and th. agreement between th. numerical.and experimental.resul.s are very good.

关键词： Natural.convection circul.r encl.sure body-fitted coordinates

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