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Novel SARS-CoV-2 outbreak and COVID19 disease;a systemic review on the global pandemic

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Genes & Diseases 2020年第4期7卷 491-501页

作者： Abdulmohsen h.al-Rohaimi Faisal al Otaibi College of Pharmacy University of ShaqraAl DawadmiSaudi Arabia Clinical Pharmacology William Harvey Research InstituteQueen Mary University of LondonCharterhouse SquareLondonEC1M6BQUK

Since the beginning of the 21st century,several viral outbreaks have threatened humankind and posed a new challenge to the modern healthcare *** recent outbreak in Wuhan(December 2019),China,represents a beta coronavirus classified as novel Severe Acute Respiratory Syndrome Corona Virus-2(SARS-CoV-2)which belongs to the Coronaviridae *** SARS-CoV-2 represents a significant similarity with previous coronaviruses such as SARS-CoV in 2002,China and mERS-CoV in 2015,middle ***,preliminary research investigations have shown the novel SARS-CoV-2 evolved with several mutations and developed the capacity to cross the species,i.e.,animal to *** initial findings have shown that spike proteins are vital molecules target hACE2 receptor for its attachment and entry into *** successful entry virus primarily focuses on respiratory airway cell lines and triggers a massive immune response leading to mucus *** severe conditions,the virus is capable of forcing viral pneumonia leading to the collapse of the respiratory system,i.e.,*** far,there is a lack of immunity against the virus in *** the same in the absence of therapeutic interventions,many countries experienced high mortality,such as the United States,European countries,i.e.,Italy,Spain,France,and the United *** vaccine development is underway and experiencing challenges,as many reports demonstrated genetic variations in viral genome and proteins as *** present study provides a complete comprehensive overview of the novel SARS-CoV-2 outbreak,human transmission,and global spread.

关键词： Centre for disease prevention and control COVID19 Diagnosis Pandemic SARS-CoV-2 Therapeutics Vaccines World health Organization

mechanical and thermodynamical stability of BiVO4 polymorphs using first-principles study

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Chinese Physics B 2017年第3期26卷 395-403页

作者： A K m Farid UI Islam md Nurul huda Liton h m Tariqul Islam md al helal md Kamruzzaman Department of Computer Science and Engineering Begum Rokeya University Rangpur Rangpur-5400 Bangladesh Department of Physics Begum Rokeya University Rangpur Rangpur-5400 Bangladesh Department of Chemistry Begum Rokeya University Rangpur Rangpur-5400 Bangladesh Department of Physics and materials Science and Center of Super-Diamond and Advanced Films (COSDAF) City University of Hong Kong Hong Kong SAR China

First principles calculations of structural, electronic, mechanical, and thermodynamic properties of different poly- morphs of BiVO4 are performed using Bender-type plane/wave ultrasoft pseudopotentials within the generalized gradient approximation （GGA） in the flame of density functional theory （DFT）. The calculated structural and electronic properties are consistent with the previous theoretical and experimental results. The electronic structures reveal that m-BiVO4, op- BiVO4, and st-BiVO4 have indirect band gaps, on the other hand, zt-BiVO4 has a direct band gap. From the DOS and mulliken＇s charge analysis, it is observed that only m-BiVO4 has 6s2 Bi lone pair. Bond population analysis indicates that st-BiVO4 shows a more ionic nature and a similar result is obtained from the elastic properties. From the elastic prop- erties, it is observed that st-BiVO4 is more mechanically stable than the others, st-BiVO4 is more ductile and useful for high electro-optical and electro-mechanical coupling devices. Our calculated thermodynamic properties confirm the similar characteristics found from electronic and elastic properties, m-BiVO4 is useful as photocatalysts, solid state electrolyte, and electrode and other polymorphs are applicable in electronic device fabrications.

关键词： BiVO4 crystal structure lone pair mechanical stability

Formulating etoposide in a nanoemulsion containing polyunsaturated fatty acids potentiates its anti-proliferation and anti-invasion activities against the ovarian cancer cells

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BIOCELL 2021年第3期45卷 695-703页

作者： mAYSON h.alKhATIB SalWA m.al-hAShEmI hANA m.GAShLAN Department of Biochemistry Faculty of ScienceKing Abdulaziz UniversityJeddahSaudi Arabia Regenerative medicine Unit King Fahd Center for Medical ResearchKing Abdulaziz UniversityJeddahSaudi Arabia

Inorporation of etoposide(ETP)into nanoemulsion(NE)containing polyunsaturated faty adids(PUFAS)may potentially augment its antiproliferation efet on the cancer cll The current study aimed to examine the in vitro antitumor activity of a novel formulation(ETP-BC/EP-NE)produced by combining the anticancer drug(ETP)with NE(BCEP-NE)consisting of the blasck currant seed and organic ewening primrose *** produced formulas were physically charaterized using 2etasizer *** ceytotoxkc efect was testfied at concentrations ranges from 0.0001 to 5μm using *** and ant-invasion efects were evaluated using the assays of mitochondrtal membrane potental,annexin V-FITC double *** fragmentation,and collagen-based cell *** to the zetasizer charaterization,the nano-suspensions of ETP-BC/EP-NE have z-average diameters of 87.63土3.30 nm with an average surface zeta potential of-0.605土0.003 mV.A reduction of 50%in the growth of SK-OV-3 cells was found at a distinetly lower concentration of ETP-BCEP-NE(IlCso=0.04土0.2μm)than that of ETP(ICsu=4.75土0.1μm).Resuts indicated that FTP-BCIEP-NE had a greater apoptotic ffect than FTP on SK-OV-3 cllsl which was attibuted to the larger amount of late apoptotic cells(41.9土1.05%)higher loss of mitochondrial membrane potential,and more intensive fragmented DNA The ETP-BC/EP-NE treatment suppressed the cllular invasion by 55%,whereas EIP impeded the ellular invasion by only 3%,Formulting ETP with PUFAs in NE had ameliorated the efcacy of ETP.

关键词： Black currant seed oil Organic evening primrose oil Chemotherapeutic agent Cellular growth Apoptosis

Big Data Bot with a Special Reference to Bioinformatics

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Computers, materials & Continua 2023年第5期75卷 4155-4173页

作者： Ahmad m.al-Omari Shefa m.Tawalbeh Yazan h.Akkam mohammad al-Tawalbeh Shima’a Younis Abdullah A.mustafa Jonathan Arnold Biomedical Systems and Informatics Engineering Department Yarmouk UniversityIrbid21163Jordan Department of medicinal Chemistry and Pharmacognosy Yarmouk UniversityIrbid21163Jordan Department of Electrical Computer and Software EngineeringUniversity of Ontario Institute of TechnologyOshawaL1H7K4Canada Department of mechanical Engineering University of MosulMosul41001Iraq Genetics Department University of GeorgiaAthens30602GAUSA

There are quintillions of data on deoxyribonucleic acid(DNA)and protein in publicly accessible data banks,and that number is expanding at an exponential *** scientific fields,such as bioinformatics and drug discovery,rely on such data;nevertheless,gathering and extracting data from these resources is a tough *** data should go through several processes,including mining,data processing,analysis,and *** study proposes software that extracts data from big data repositories automatically and with the particular ability to repeat data extraction phases as many times as needed without human *** software simulates the extraction of data from web-based(point-and-click)resources or graphical user interfaces that cannot be accessed using command-line *** software was evaluated by creating a novel database of 34 parameters for 1360 physicochemical properties of antimicrobial peptides(AmP)sequences(46240 hits)from various mARVIN software panels,which can be later utilized to develop novel ***,for machine learning research,the program was validated by extracting 10,000 protein tertiary structures from the Protein Data *** a result,data collection from the web will become faster and less expensive,with no need for manual data *** software is critical as a first step to preparing large datasets for subsequent stages of analysis,such as those using machine and deep-learning applications.

关键词： Bioinformatics big data data extraction bot drug design

Control of hybrid DC/AC microgrid system employing fuel cell and solar photovoltaic sources using grey wolf optimization

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Clean Energy 2022年第4期6卷 659-670页

作者： Ahmed m.al-Antaki T.V.Golubchik mushtaq A.al-Furaiji h.J.mohammed moscow Automobile and Road Construction State Technical University(mADI) Leningradsky Ave.64Moscow125319Russian Federation Bauman moscow State Technical University MoscowRussian Federation Faculty of Energy and Ecotechnology ITMO University49 Kronverksky prospectSt.Petersburg197101Russian Federation Department of mechanical Engineering College of EngineeringUniversity of MisanMisanAl-Amarah62001Iraq Institute of Energy Peter the Great St.Petersburg Polytechnic UniversitySaint Petersburg 195251Russian Federation

The outcome of this study is to improve and enhance the power quality of the hybrid DC/AC microgrid(mG).The photovoltaic(PV)system and the proton exchange membrane fuel cell(PEmFC)are used as renewable energy sources to deliver the optimum active power to the utility *** mG system based on the PV system,PEmFC and voltage source inverter is modelled ***,the maximum power point tracking(mPPT)-based grey wolf optimization(GWO)is used to increase the PV module efficiency and enhance ***,to improve the PEmFC performance,a digital proportional-integral controller is used to control the PEmFC *** proposed inverter is controlled using synchronous reference frame theory,called the direct-quadrature(dq)control ***,the performance of the proposed mG system is tested using mATLAB®for various weather and loading condi*** the simulation results,the proposed mG system can deliver and absorb an active power based on the PV and fuel cell *** a result,the hybrid DC/AC mG is enhanced in terms of stabilization of the DC-bus ***,the power quality of the mG is improved using GWO optimization based on ***,good results are achieved using GWO in terms of the total harmonic distortion of the output current of 2.3%and higher efficiency of 98.9%.

关键词： DC/AC inverter optimization

Biogenic amino acid methionine-based corrosion inhibitors of mild steel in acidic media

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International Journal of minerals,metallurgy and materials 2019年第4期26卷 467-482页

作者： L.K.m.O.Goni m.A.Jafar mazumder S.A.ali m.K.Nazal h.A.al-muallem Chemistry Department King Fahd University of Petroleum and Minerals

N,N-Diallyl methionine ethyl ester hydrochloride 5 underwent alternating copolymerization with SO_2 via the Butler cyclopolymerization protocol in dimethyl sulfoxide(DmSO) to give water-soluble cycloterpolymer 6 with a ～1:1 molar ratio of sulfide and sulfoxide groups as a result of oxygen transfer from DmSO. half of the sulfide groups in 6, upon oxidation with h_2O_2, afforded polymer sulfoxide 7 and polymer sulfone 8. The solution properties of these polymers were determined via a viscometric technique. The thermal stability of these polymers was determined by thermogravimetric analysis. The inhibition efficiency obtained from gravimetric mass loss, potentiodynamic polarization, and electrochemical impedance spectroscopy techniques agreed well with each other. The corrosion efficiencies increase with increasing concentration of the polymers. At a polymer concentration of 175 mm, the maximum inhibition efficiency of copolymer compounds 6–8 was determined to be 92%, 97%, and 95%, respectively. The synthesized polymer compounds acted as mixed-type inhibitors. Polymer compound 7 adsorbed onto the metal surface via chemisorption and physisorption and obeyed Langmuir, Temkin, and Freundlich adsorption isotherms. Analyses by X-ray photoelectron spectroscopy and scanning electron microscopy–energy-dispersive X-ray spectroscopy indicated that the adsorbed polymers formed a thin film on the metal surface and prevented further corrosive attack.

关键词： cyclopolymerization methionine methionine sulfoxide methionine sulfone diallylamine salt corrosion inhibition

The Effects of Thermal Radiation and Viscous Dissipation on the Stagnation Point Flow of a micropolar Fluid over a Permeable Stretching Sheet in the Presence of Porous Dissipation

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Fluid Dynamics & materials Processing 2023年第1期19卷 61-81页

作者： muhammad Salman Kausar h.A.m.al-Sharifi Abid hussanan mustafa mamat Faculty of Informatics and Computing University Sultan Zainal Abidin(Kampus Gong Badak)Kuala TerengganuTerengganuMalaysia Department of mathematics College of Education for Pure SciencesUniversity of KerbalaKerbalaIraq Department of mathematics Division of Science and TechnologyUniversity of EducationLahorePakistan

In this paper,the effects of thermal radiation and viscous dissipation on the stagnation–point flow of a micropolar fluid over a permeable stretching sheet with suction and injection are analyzed and discussed.A suitable similarity transformation is used to convert the governing nonlinear partial differential equations into a system of nonlinear ordinary differential equations,which are then solved numerically by a fourth–order Runge–Kutta *** is found that the linear fluid velocity decreases with the enhancement of the porosity,boundary,and suction ***,it increases with the micropolar and injection *** angular velocity grows with the boundary,porosity,and suction parameters,whereas it is reduced if the micropolar and injection parameters become *** is concluded that the thermal boundary layer extension increases with the injection parameter and decreases with the suction parameter.

关键词： micropolar fluid viscous dissipation stagnation point stretching sheet porous media thermal radiation

machine Learning Approach for COVID-19 Detection on Twitter

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Computers, materials & Continua 2021年第8期68卷 2231-2247页

作者： Samina Amin m.Irfan Uddin heyam h.al-Baity m.ali Zeb m.Abrar Khan Institute of Computing Kohat University of Science and TechnologyKohat26000Pakistan Department of Information Technology College of Computer and Information SciencesKing Saud UniversityRiyadh11543Saudi Arabia

Social networking services(SNSs)provide massive data that can be a very influential source of information during pandemic *** study shows that social media analysis can be used as a crisis detector(e.g.,understanding the sentiment of social media users regarding various pandemic outbreaks).The novel Coronavirus Disease-19(COVID-19),commonly known as coronavirus,has affected everyone worldwide in *** Twitter data have revealed the status of the COVID-19 outbreak in the most affected *** study focuses on identifying COVID-19 patients using tweets without requiring medical records to find the COVID-19 pandemic in Twitter messages(tweets).For this purpose,we propose herein an intelligent model using traditional machine learning-based approaches,such as support vector machine(SVm),logistic regression(LR),naïve Bayes(NB),random forest(RF),and decision tree(DT)with the help of the term frequency inverse document frequency(TF-IDF)to detect the COVID-19 pandemic in Twitter *** proposed intelligent traditional machine learning-based model classifies Twitter messages into four categories,namely,confirmed deaths,recovered,and *** the experimental analysis,the tweet data on the COVID-19 pandemic are analyzed to evaluate the results of traditional machine learning approaches.A benchmark dataset for COVID-19 on Twitter messages is developed and can be used for future research *** experiments show that the results of the proposed approach are promising in detecting the COVID-19 pandemic in Twitter messages with overall accuracy,precision,recall,and F1 score between 70%and 80%and the confusion matrix for machine learning approaches(i.e.,SVm,NB,LR,RF,and DT)with the TF-IDF feature extraction technique.

关键词： Artificial intelligence coronavirus COVID-19 pandemic social network Twitter machine learning natural language processing

Temperature effect on the corrosion and passivation characterization of Ni_(82.3)Cr_7Fe_3Si_(4.5)B_(3.2) alloy in acidic media

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International Journal of minerals,metallurgy and materials 2016年第2期23卷 205-214页

作者： Khadijah m.Emran Sanaa T.Arab Aisha m.al-Turkustani hamad A.al-Turaif Chemistry Department Faculty of Science Taibah University Department of Chemistry Faculty of Sciences Al-Faisaliah King Abdulaziz University Department of Chemical and materials Engineering King Abdulaziz University

The effects of temperature on corrosion and the electrochemical behavior of Ni82.3Cr7Fe3Si4.5B3.2 glassy alloy in hC1,h2SO4,and h3PO4 acids were studied using AC and DC *** data reveal that the susceptibility to localized corrosion increases with increasing *** polarization curves reveal that the bulk glassy alloy is spontaneously passivated at all the investigated temperature in h2SO4 and h3PO4 solutions.A localized corrosion effect in hCl solution is clearly *** apparent activation energies in the regions of Tafel,active,and passive,as well as the enthalpies and entropies of the dissolution process were determined and *** high apparent activation energy（Ea） value for h3PO4 solution in Tafel region is explained by the low aggressivity of PO4^3- ions.

关键词： nickel alloys corrosion temperature effect acidic environment passivation polarization