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Tumor size discrepancy between endoscopic and pathological evaluations in colorectal endoscopic submucosal dissection

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World Journal of Gastrointestinal Endoscopy 2024年第3期16卷 136-147页

作者： Takeshi Onda Osamu Goto Toshiaki Otsuka Yoshiaki hayasaka Shun Nakagome Tsugumi habu Yumiko Ishikawa Kumiko Kirita Eriko Koizumi hiroto Noda Kazutoshi higuchi Jun Omori Naohiko Akimoto Katsuhiko Iwakiri Department of Gastroenterology Nippon Medical SchoolGraduate School of MedicineBunkyo-ku 113-8603TokyoJapan Endoscopy Center Nippon Medical School HospitalBunkyo-ku 113-8603TokyoJapan Department of hygiene and Public health Nippon Medical SchoolBunkyoku 113-8603TokyoJapan Center for Medical Education Nippon Medical SchoolBunkyo-ku 113-8603TokyoJapan

BACKGROUND Tumor size impacts the technical difficulty and histological curability of colorectal endoscopic submucosal dissection(ESD);however,the preoperative evaluation of tumor size is often different from histological *** influential factors on failure to obtain an accurate tumor size evaluation could help prepare optimal conditions for safer and more reliable *** This was a retrospective study conducted at a single institution.A total of 377 lesions removed by colorectal ESD at our hospital between April 2018 and March 2022 were *** first assessed the difference in size with an absolute per-centage of the scaling ***,we compared the clinicopatho-logical characteristics of the correct scaling group(>-33%andh that of the incorrect scaling group(33%),which was further subdivided into the underscaling group(-33%or less of the discrepancy)and overscaling group(33%or more of the discrepancy),*** secondary outcome measures,parameters on size estimation were compared between the underscaling and correct scaling groups,as well as between the overscaling and correct scaling ***,multivariate analysis was performed in terms of the following relevant parameters on size estimation:Pathological size,location,and possible influential factors(Phe univariate *** The mean of absolute percentage in the scaling discordance was 21%,and 91 lesions were considered to be incorrectly estimated in *** incorrect scaling was significantly remarkable in larger lesions(40 mm vs 28 mm;Phese two factors were influential on the underscaling(75 lesions;Ph the correct scaling group,16 lesions in the overscaling group were significantly small(20 mm vs 28 mm;Phe small lesion size was influential on the overscaling(P=0.002).CONCLUSION Lesions indicated for colorectal ESD tended to be underestimate

关键词： Endoscopic submucosal dissection Colorectal tumor Tumor size Size estimation Size discrepancy

Impacts of invasive Iris pseudacorus L.(yellow flag) establishing in an abandoned urban pond on native semi-wetland vegetation

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Journal of Integrative Agriculture 2018年第8期17卷 1881-1887页

作者： Daisuke hayasaka Shingo Fujiwara Taizo Uchida Graduate School of Agriculture KINDAI University Faculty of Engineering Kyushu Sangyo University

Iris pseudacorus L., intentionally introduced in Japan as an ornamental plant and to improve aquatic environments, has been declared a noxious species in the Invasive Alien Species Act of Japan due to the suspected high ecological risks to the local species and ecosystems. Although prompt responses to I. pseudacorus have been sought to conserve local biodiversity, knowledge about its invasiveness is lacking. here, we report the relationship between the establishment of I. pseudacorus and floristic changes in semi-wetland vegetation of an abandoned urban pond(Aoike), Nara City, Nara Prepecture, Japan. In total, 64 vascular plants were recorded in the pond, of which 50 were native species, seven were naturalized non-native, and seven were invasive species. On the other hand, most of these vascular plants(42 species) were grassland species and only several aquatic plants(10 species) were found in this study pond. The number of vascular plant species decreased significantly at quadrats with a coverage of I. pseudacorus above 50%. In addition, tendencies of lower number of native species and concomitant higher number of invasive species were found with increasing coverage of I. pseudacorus. From these results, we suggest that it is important to preferentially manage sites where the coverage of I. pseudacorus is above 50%, in order to preserve the local biodiversity. Additionally, as recommended in the literature, it is essential that the cut reproductive organs are kept submerged under deep water for an effective control of I. pseudacorus.

关键词： biodiversity conservation biological invasions ecological impacts exotic species hydrophytes species traits

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Effects of the aluminum concentration on twin boundary motion in pre-strained magnesium alloys

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Journal of Materials Science & Technology 2021年第14期73卷 116-127页

作者： Yujie Cui Kenta Aoyagi huakang Bian Yuichiro hayasaka Akihiko Chiba Institute for Materials Research Tohoku UniversitySendai 980-8577Japan The Electron Microscopy Center Tohoku UniversitySendai 980-8577Japan

We investigated the effects of Al concentration on the reciprocated motion of twin boundaries in pre-strained Mg-Al-Zn alloys through a combination of applied compression and tension,in-situ electron-backscattering diffraction observations,and high-angle annular dark-field scanning transmission electron microscopy *** twin growth was restricted by increased Al concentration,which resulted in the occurrence of smaller-sized *** reverse motion of twin boundaries was also restricted,resulting in the formation of higher fractions of secondary twins and 2–5°boundaries during reverse *** secondary twins and 2–5°boundaries mainly contributed to the increased ultimate tensile strength of the pre-strained Mg *** effect is more significant in Mg alloys with larger ***,the increased amount of the Al solute atoms,rather than the precipitates,mainly contributed to the increased strengthening effect on the twin boundary *** research contributes to development of high-strength Mg alloys by stabilizing twin boundaries.

关键词： hexagonal close packed Magnesium alloy Twinning Dislocations Strength Solute atoms

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Discovery of Paleozoic rocks at northern margin of Sambagawa terrane,eastern Kyushu,Japan:Petrogenesis,U-Pb geochronology and its tectonic implication

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Geoscience Frontiers 2020年第4期11卷 1441-1459页

作者： Kenta Kawaguchi Yasutaka hayasaka Tomoyuki Shibata Masayuki Komatsu Kosuke Kimura Kaushik Das Department of Earth and Planetary Systems Science Graduate School of ScienceHiroshima University1-3-1 KagamiyamaHigashi-HiroshimaHiroshima739-8526Japan hiroshima Institute of Plate Convergence Region Research 1-3-1 KagamiyamaHigashi-HiroshimaHiroshima739-8526Japan Ehime University 10-13 Dogo-HimataMatsuyamaEhime790-8577Japan

Ordovician diorite-quartz diorite mylonite(Saganoseki quartz diorite) was discovered in Sambagawa metamorphic terrane at the northern margin of Saganoseki Peninsula,Kyushu Island,*** LA-ICP-MS zircon U-Pb geochronology revealed that the intrusion age of Saganoseki quartz diorite was 473.3±3.6 *** rocks show the volcanic arc affinity based on the trace element *** the basis of geochronological and geochemical results,Saganoseki quartz diorite is considered to be a member of the Early Paleozoic igneous rocks of the Kurosegawa tectonic *** quartz diorite is located just south of the Median Tectonic Line(MTL)and is in close contact with the pelitic and psammitic schist without any brittle shear zone.U-Pb ages of detrital zircon grains from two psammitic schists show the estimated sedimentation age of early Late Cretaceous,indicate that these psammitic schists are the member of Sambagawa metamorphic *** with these results and the mode of occurrence in the field,we argue that the Early Paleozoic igneous rocks of the Kurosegawa tectonic zone existed as an upper structural unit of the Sambagawa *** relationship is the key to reconstruct the Mesozoic tectonics of Japan as a part of East Asia,and its evolution through time.

关键词： Outer zone of southwest Japan Sambagawa metamorphic terrane Kurosegawa tectonic zone LA-ICP-MS zircon U-Pb age Saganoseki quartz diorite

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A NEW LOCALITY OF GIGANTOPTERIS IN SOUThERN ChINA

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地质学报 1924年第1期 31-36+91-94页

作者： IChIR? hayasaka Assistant Professor of Geology Tohoku Imperial University Sendai Japan

Ⅰ. Introduction Our knowledge concerning the geological and geographical ranges of the genus Gigantopteris was summarized by Prof. h. Yabe in one of his papers published in the year 1917, in which Mr. K. Koiwai descr... 详细信息

关键词： A NEW LOCALITY OF GIGANTOPTERIS IN SOUThERN ChINA very

Intramanchette transport during primate spermiogenesis： expression of dynein, myosin Va, motor recruiter myosin Va, VIIa-Rab27a/b interacting protein, and Rab27b in the manchette during human and monkey spermiogenesis

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Asian Journal of Andrology 2008年第4期10卷 561-568页

作者： Shinichi hayasaka Yukihiro Terada Kichiya Suzuki haruo Murakawa Ikuo Tachibana Tadashi Sankai Takashi Murakami Nobuo Yaegashi Kunihiro Okamura Department of Obstetrics and Gynecology Tohoku University School of Medicine Sendai Miyagi 980-8574 Japan Suzuki Memorial hospital lwanuma Miyagi 989-2481 Japan Tsukuba Primate Research Center National Institute of Biomedical Innovation Tukuba Ibaraki 305-0843 Japan

Aim： To show whether molecular motor dynein on a microtubule track, molecular motor myosin Va, motor recruiter myosin Va, VIIa-Rab27a/b interacting protein （MyRIP）, and vesicle receptor Rab27b on an F-actin track were present during human and monkey spermiogenesis involving intramanchette transport （IMT）. Methods： Spermiogenic cells were obtained from three men with obstructive azoospermia and normal adult cynomolgus monkey （Macacafascieularis）. Immunocytochemical detection and reverse transcription-polymerase chain reaction （RT-PCR） analysis of the proteins were carried out. Samples were analyzed by light microscope. Results： Using RT-PCR, we found that dynein, myosin Va, MyRIP and Rab27b were expressed in monkey testis. These proteins were localized to the manchette, as shown by immunofluorescence, particularly during human and monkey spermiogenesis. Conclusion： We speculate that during primate spermiogenesis, those proteins that compose microtubule-based and actin-based vesicle transport systems are actually present in the manchette and might possibly be involved in intramanchette transport.

关键词： intramanchette transport manchette spermiogenesis

Recent Active Fires under El Nino Conditions in Kalimantan,Indonesia

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American Journal of Plant Sciences 2013年第3期4卷 685-696页

作者： Nina Yulianti hiroshi hayasaka Graduate School of Engineering Hokkaido UniversitySapporoJapan

Analysis of the most recent 10-year periods (2002 to 2011) of MODIS hotspots data (fires) and precipitation in Palangkaraya and Pontianak was carried out to identify seasonal and spatial fire occurrence in Kalimantan under El Nino conditions, and to asses future forest condition in Kalimantan. Most data was tallied every 10-day to analyze seasonal and spatial fire occurrence. Seasonal and spatial analysis results for severe fire years, namely 2006 and 2009, under El Nino conditions were as follows: the severest fire incidents for whole Kalimantan occurred in October in 2006 under the driest conditions in both Palangkaraya and Pontianak. The severest fires for the Mega Rice Project (MRP) area and its vicinity occurred in late September in 2009 under the driest conditions for Palangkaraya. Fire activities in the last 10-year in south Central Kalimantan were severe than other areas in Kalimantan. This may be explained by different dry conditions of peat. Namely, the peat in the southern part of Central Kalimantan could become dryer under the relatively longer dry season (about 3-month) compared with other areas (dry season in West Kalimantan is only 2/3-month). One of spatial analysis results clearly showed a so-called a fire belt shape arising from severe fires that occurred mainly on the southern coastal peatlands from West to Central Kalimantan in mid October in 2006.

关键词： Dry Season El Nino MODIS hotspot MRP Peat Fire

Feasibility of gastric endoscopic submucosal dissection with continuous low-dose aspirin for patients receiving dual antiplatelet therapy

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World Journal of Gastroenterology 2019年第4期25卷 457-467页

作者： hideaki harada Satoshi Suehiro Daisuke Murakami Ryotaro Nakahara Takuya Nagasaka Tetsuro Ujihara Ryota Sagami Yasushi Katsuyama Kenji hayasaka Yuji Amano Department of Gastroenterology New Tokyo Hospital Department of Endoscopy New Tokyo Hospital

BACKGROUND Endoscopic submucosal dissection(ESD) for gastric neoplasms during continuous low-dose aspirin(LDA) administration is generally acceptable according to recent guidelines. This retrospective study aimed to investigate the effect of continuous LDA on the postoperative bleeding after gastric ESD in patients receiving dual antiplatelet therapy(DAPT).AIM To investigate the feasibility of gastric ESD with continuous LDA in patients with *** A total of 597 patients with gastric neoplasms treated with ESD between January2010 and June 2017 were enrolled. The patients were categorized according to type of antiplatelet therapy(APT).RESULTS The postoperative bleeding rate was 6.9%(41/597) in all patients. Patients were divided into the following two groups: no APT(n = 443) and APT(n = 154). APT included single-LDA(n = 95) and DAPT(LDA plus clopidogrel, n = 59)subgroups. In the single-LDA and DAPT subgroups, 56 and 39 patients were received continuous LDA, respectively. The bleeding rate with continuous singleLDA(10.7%) was similar to that with discontinuous single-LDA(10.3%)(P >0.99). Although the bleeding rate with continuous LDA in patients receiving DAPT(23.1%) was higher than that with discontinuous LDA in patients receiving DAPT(5.0%), no significant difference was observed(P = 0.141).CONCLUSION The bleeding rate with continuous LDA in patients receiving DAPT was not statistically different from that with discontinuous LDA in patients receiving DAPT. Therefore, continuous LDA administration may be acceptable for ESD in patients receiving DAPT, although patients should be carefully monitored for possible bleeding.

关键词： Dual antiplatelet therapy Endoscopic submucosal dissection Low-dose aspirin Postoperative bleeding Thienopyridine

Recent Trends of Fire Occurrence in Sumatra(Analysis Using MODIS hotspot Data):A Comparison with Fire Occurrence in Kalimantan

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Open Journal of Forestry 2013年第4期3卷 129-137页

作者： Nina Yulianti hiroshi hayasaka Alpon Sepriando Graduate School of Engineering Hokkaido UniversitySapporoJapan Meteorological Climatology and Geophysical Agency of Central KalimantanPalangkarayaIndonesia

MODIS (Moderate Resolution Imaging Spectroradiometer) hotspot and precipitation data for the most recent 11-year period (2002 to 2012) were analyzed to elucidate recent trends in the seasonal and spatial fire occurrence in Sumatra and the relationship with precipitation. Using a latitude line of S 0.5°, Sumatra was divided into two regions, N. (north) and S. (south) Sumatra. Different trends in seasonal fire occurrence were discussed and further defined by considering two different precipitation patterns. Analysis of hotspot (fire) data was carried out using 0.5° × 0.5° grid cells to evaluate recent trends of spatial fire occurrence. Analysis results of hotspot and precipitation data were also tallied every 10-day to find the relationship between seasonal fire occurrence and the dry season. Standard deviation (SD) and variance (V) were then used to evaluate fire occurrences in Sumatra and Kalimantan objectively. The relatively mild fire occurrence tendency in Sumatra compared to Kalimantan could be the result of different stages of forest development or the high deforestation rate in Sumatra compared with Kalimantan. This paper also shows that the two different seasonal fire activities in N. and S. Sumatra were closely related to the two different dry season types: a winter and summer dry season type (WD & SD) in N. Sumatra, and a summer dry season type (SD) in S. Sumatra. Extreme fire occurrences in the Dumai region in 2005 and Palembang region in 2006 could be partially explained by a severe drought occurrence enhanced by two different kinds of El Nino events.

关键词： Drought Dry Season El Nino MODIS hotspot Peatland Fire