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Polysorb^R(an absorbable lactomer) staples, a safe closure technique for distal pancreatic resection

World Journal of Gastroenterology 2014年第45期20卷 17185-17189页

作者： gyula farkas László Leindler János Márton Gyorgy Lázár gyula farkas Department of Surgery Faculty of Medicine University of Szeged H-6701 SzegedHungary

AIM:To investigate twenty-year experience evaluated the use of the PolysorbR(an absorbable lactomer)staples for distal pancreatic ***:The data on 150 patients[92 men,58women,mean age 52(24-72)years]who underwent distal pancreatectomy(DP)in the last 20 years were collected prospectively from an electronic *** diagnosis was confirmed by endoscopic retrograde cholangiopancreatography,sonography,computed tomography and/or magnetic resonance *** indications for DP were focal pancreatic necrosis,spontaneous pancreatic fistulas,abscesses,pseudocysts,segmental chronic obstructive pancreatitis in the tail,traumatic disruption,and benign(cystadenomas,insulinomas,or glucagonomas)or malignant *** distal resections were performed without splenectomy in 29 of the 150 patients(19%).In the event of splenectomy,the splenic artery and vein were individually ligated,the TA-55 Auto Suture stapler,loaded with Premium PolysorbR 55 staples(5.5mm),was placed across the gland,and the trigger was pulled,the action of which produced two staggered absorbable suture *** gland distal to the stapler wasthen amputated with a scalpel on the TA-55 stapler and the two rows of staples were left in the proximal pancreatic *** the distal resection,a drainage tube was inserted into the pancreatic ***:The average duration of the operation was150 min(range:90-210 min)and no transfusion was indicated during the *** DP in one patient a type B fistula was diagnosed,which was treated successfully by conservative treatment comprising of 12-d octreotide medication(3×0.1 mg/d)and jejunal *** incidence of postoperative pancreatic fistula was therefore0.6%.Another 2 patients suffered postoperative pancreatitis,which was also conservatively *** were performed in 2 patients on the first or second postoperative day,necessitated by bleeding from the retroperitoneal *** morbidity was 3.3%(5 patients),but no mortality

关键词： Distal pancreatic resection PolysorbR sta-ples Closure technique Long-term experience Pancre-atic fistula

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Management of the Case of a Young Female Patient with Multiple Malignancies and Germline R24P CDKN2A Gene Mutation

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Journal of Cancer Therapy 2013年第7期4卷 18-20页

作者： Gabriella Uhercsak Agnes Dobi Roland gyulai Judit Olah Laszlo Kaizer Katalin Ormandi Adrienne Cserhati Gyorgy Lazar gyula farkas Zsuzsanna Kahan Department of Oncotherapy University of SzegedSzegedHungary Department of Dermatology and Immunology University of SzegedSzegedHungary Department of Pathology University of SzegedSzegedHungary Department of Radiology University of SzegedSzegedHungary Euromedic Diagnostics Hungary Ltd. SzegedHungary Department of Surgery University of SzegedSzegedHungary

The case of a young female patient with metachronous primary melanomas, advanced breast and pancreatic cancers is reported. The 5 different tumors diagnosed within six years, were managed with curative intent. Genetic analysis revealed the mutation of the R24P CDKN2A gene in a heterozygote form in both the patient and her father. Careful tertiary prevention during the follow-up of the patient is needed.

关键词： Breast Cancer Melanoma Pancreatic Cancer R24P CDKN2A Gene Mutation

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