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Satellite-enabled enviromics to enhance crop improvement

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Molecular Plant 2024年第6期17卷 848-866页

作者： Rafael T.Resende Lee hickey cibele h.Amaral Lucas L.Peixoto gustavo E.Marcatti Yunbi Xu Universidade Federal de Goia´s(UFG) Agronomy DepartmentPlant Breeding SectorGoiania(GO)74690-900Brazil ThecROP a Precision-Breeding Startup:EnviromicsPhenomicsand GenomicsNo Zip-codeOperating VirtuallyGoiania(GO)and Sete Lagoas(MG)Brazil Queensland Alliance for Agriculture and Food Innovation The University of QueenslandBrisbaneQLDAustralia Earth Lab Cooperative Institute for Research in Environmental SciencesUniversity of Colorado BoulderBoulderCO 80303USA Environmental Data Science Innovation&Inclusion Lab Cooperative Institute for Research in Environmental SciencesUniversity of Colorado BoulderBoulderCO 80303USA Universidade Federal de Sa˜o Joa˜o del-Rei Forest Engineering DepartmentCampus Sete LagoasSete Lagoas(MG)35701-970Brazil Institute of crop Sciences Chinese Academy of Agricultural SciencesBeijing 100081China Peking University Institute of Advanced Agricultural Sciences WeifangShandong 261325China BGI Bioverse Shenzhen 518083China

Enviromics refers to the characterization of micro-and macroenvironments based on large-scale environmental *** providing genotypic recommendations with predictive extrapolation at a site-specific level,enviromics could inform plant breeding decisions across varying conditions and anticipate productivity in a changing ***-based integration of statistics,envirotyping(i.e.,determining environmental factors),and remote sensing could help unravel the complex interplay of genetics,environment,and *** support this goal,exhaustive envirotyping to generate precise environmental profiles would significantly improve predictions of genotype performance and genetic gain in ***,informatics management platforms aggregate diverse environmental datasets obtained using optical,thermal,radar,and light detection and ranging(LiDAR)sensors that capture detailed information about vegetation,surface structure,and *** wealth of information,coupled with freely available climate data,fuels innovative enviromics *** enviromics holds immense potential for breeding,a few obstacles remain,such as the need for(1)integrative methodologies to systematically collect field data to scale and expand observations across the landscape with satellite data;(2)state-of-the-art AI models for data integration,simulation,and prediction;(3)cyberinfrastructure for processing big data across scales and providing seamless interfaces to deliver forecasts to stakeholders;and(4)collaboration and data sharing among farmers,breeders,physiologists,geoinformatics experts,and programmers across research *** these challenges is essential for leveraging the full potential of big data captured by satellites to transform 21st century agriculture and crop improvement through enviromics.

关键词： envirotyping precision breeding genotype-environment interactions remote sensing predictive models enviromic information

Seasonal variation and host sex affect bat–bat fly interaction networks in the Amazonian savannahs

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Integrative Zoology 2024年第3期19卷 400-416页

作者： Paulo MEJIA gustavo Lima URBIETA Bruna da Silva XAVIER IsaíJorge de cASTRO JoséJúlio DE TOLEDO gustavo GRAcIOLLI Lucio AndréVIANA DIAS William Douglas cARVALhO Programa de Pós-Graduação em Biodiversidade Tropical Universidade Federal do Amapá(UNIFAP)MacapáAPBrazil Programa de Pós-Graduação em Ecologia Instituto de BiologiaCentro de Ciências da SaúdeUniversidade Federal do Rio de Janeiro(UFRJ)Rio de JaneiroRJBrazil Laboratório de Mamíferos Instituto de Pesquisas Científicas e Tecnológicas do Estado do Amapá(IEPA)MacapáAPBrazil Programa de Pós-Graduação em Biologia Animal Laboratório de SistemáticaEcologia e Evolução(LSEE)Instituto de BiociênciasUniversidade Federal de Mato Grosso do Sul(UFMS)Campo GrandeMTBrazil Terrestrial Ecology Group(TEG-UAM) Departamento de EcologíaFacultad de CienciasUniversidad Autónoma de MadridMadridSpain centro de Investigación en Biodiversidad y cambio Global(cIBc-UAM) Universidad Autónoma de MadridMadridSpain

Bats are the second-most diverse group of mammals in the world,and bat flies are their main ***,significant knowledge gaps remain regarding these antagonistic interactions,especially since diverse factors such as seasonality and host sex can affect their network ***,we explore the influence of such factors by comparing species richness and composition of bat flies on host bats,as well as specialization and modularity of bat–bat fly interaction networks between seasons and adult host *** captured bats and collected their ectoparasitic flies at 10 sampling sites in the savannahs of AmapáState,northeastern region of the Brazilian *** female bats being more parasitized and recording greater bat fly species richness in the wet season,neither relationship was statistically *** pooled network could be divided into 15 compartments with 54 links,and all subnetworks comprised>12 *** total number of links ranged from 27 to 48(for the dry and wet seasons,respectively),and female and male subnetworks had 44 and 41 links,*** values were very low for the pooled network and for all *** results revealed higher bat fly species richness and abundance in the wet season,whereas specialization and modularity were higher in the dry ***,the subnetwork for female bats displayed higher specialization and modularity than the male ***,both seasonality and host sex contribute in different ways to bat–bat fly network *** studies should consider these factors when evaluating bat–bat fly interaction networks.

关键词： Amapá Amazon biome bat flies bats interaction networks

continuous Lithium-Ion Extraction From Seawater and Mine Water With a Fuel cell System and ceramic Membranes

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Energy & Environmental Materials 2024年第6期7卷 254-261页

作者： cansu Kök Lei Wang Jean gustavo A.Ruthes Antje Quade Matthew E.Suss Volker Presser INM–Leibniz Institute for New Materials Campus D2266123Saarbr¨uckenGermany Department of Materials Science&Engineering Saarland UniversityCampus D2266123Saarbr¨uckenGermany Leibniz Institute for Plasma Science and Technology Felix-Hausdorff-Straße 217489GreifswaldGermany Faculty of Mechanical Engineering Technion–Israel Institute of TechnologyHaifa3200003Israel Wolfson Department of chemical Engineering Technion–Israel Institute of TechnologyHaifa3200003Israel Grand Technion Energy Program Technion–Israel Institute of TechnologyHaifa3200003Israel Saarene–Saarland center for Energy Materials and Sustainability Campus C4266123Saarbr¨uckenGermany

The demand for electronic devices that utilize lithium is steadily increasing in this rapidly advancing technological *** high-purity lithium in an environmentally friendly way is challenging by using commercialized ***,we propose the first fuel cell system for continuous lithium-ion extraction using a lithium superionic conductor membrane and advanced *** fuel cell system for extracting lithium-ion has demonstrated a twofold increase in the selectivity of Li^(+)/Na^(+)while producing *** data show that the fuel cell with a titania-coated electrode achieves 95%lithium-ion purity while generating 10.23 Wh of energy per gram of *** investigation revealed that using atomic layer deposition improved the electrode's uniformity,stability,and electrocatalytic *** 2000 cycles determined by cyclic voltammetry,the electrode preserved its stability.

关键词： atomic layer deposition cation selectivity electrochemical lithium-ion extraction fuel cell

Solar-driven cO_(2) conversion to methane and methanol using different nanostructured cu_(2)O-based catalysts modified with Au nanoparticles

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Journal of Energy chemistry 2024年第4期91卷 287-298页

作者： João Angelo Lima Perini Lilian D.Moura Torquato Juliana Fde Brito gustavo A.Andolpho Mateus A.Gonçalves Leonardo D.De Angelis Lucas D.Germano Susana I.córdoba de Torresi Teodorico c.Ramalho Maria V.Boldrin Zanoni São Paulo State University(UNESP) Institute of ChemistryRua Prof.Francisco Degni55AraraquaraSP 14800-060Brazil National Institute of Alternative Technologies for Detection Toxicological Evaluation and Removal of Micropollutants and Radioactive Substances(INCT-DATREM)São Paulo State University(UNESP)Institute of ChemistryRua Prof.Francisco Degni55AraraquaraSP 14800-060Brazil Laboratory of Molecular Modelling Department of ChemistryNatural Sciences InstituteFederal University of LavrasLavrasMG 37200-900Brazil Department of chemistry Faculty of ScienceUniversity of Hradec KrálovéHradec Králové50003Czech Republic Instituto de Química Universidade de São PauloAv.Prof.Lineu Prestes 74805508-080São PauloSPBrazil

This work describes the use of TiO_(2)nanotubes-based electrodes(TNT)modified with cu_(2)O nanostructures and gold nanoparticles for the photoelectroreduction of cO_(2)to produce value-added compounds.A thin layer of polydopamine was used as both an adherent agent and an electron transfer mediator,due to itsπ-conjugated electron *** highest production yield was achieved using a TNT@PDA/Nc/Au40%electrode,with Faradaic efficiencies of 47.4%(110.5μM cm^(-2))and 27.8%(50.4μM cm^(-2))for methanol and methane,*** performance of the photoelectrodes was shown to be cu_(2)O facet-dependent,with cubic structures leading to greater conversion of cO_(2)to methanol(43%)and methane(27%),compared to the octahedral morphology,while a higher percentage of metallic gold on the nanostructured cu_(2)O surface was mainly important for *** functional theory(DFT)calculations supported these findings,attributing the superior photoelectrocatalytic performance of the TNT@PDA/Nc/Au40%electrode for ch4generation to the formation of an Och3intermediate bonded to Au *** using isotope-labeling and analysis by gas chromatograph-mass(Gc-MS)demonstrated that13cO_(2)was the source for photoelectrocatalytic generation of13ch3Oh and13ch313ch2Oh.

关键词： cu_(2)O nanocubes Photoelectrocatalysis Polydopamine cO_(2) photoelectroreduction DFT calculations

Determinant variables on the isotopic values of particulate organic matter in a neotropical floodplain

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Journal of Oceanology and Limnology 2024年第4期42卷 1173-1185页

作者： Vinícius de ANDRADE URBANO Matheus MAXIMILIAN RATZ ScOARIZE gustavo hENRIQUE ZAIA ALVES Driele DELANIRA-SANTOS Marcela da SILVA cAETANO Evanilde BENEDITO Departamento de Biologia(DBI) Laboratório de Ecologia EnergéticaUniversidade Estadual de Maringá(UEM)Maringá87020-900Brasil Programa de Pós-graduação em Ecologia de Ambientes Aquáticos continentais(PEA) Universidade Estadual de Maringá(UEM)Maringá87020-900Brasil Departamento de Biologia Geral Universidade Estadual de Ponta Grossa(UEPG)Campus UvaranasPonta Grossa 84030-900Brasil Australian Rivers Institute(ARI) Griffith UniversityNathan QLD 4111Australia

Particulate organic matter(POM)is an important energy source for aquatic consumers,understanding its origin and composition is essential for understanding the energetic dynamics of aquatic *** aim of this study was to analyze the relationship between POM and phytoplankton(isotopic values and chlorophyll concentration)and abiotic variables during dry and rainy *** was conducted in rivers and lagoons in the floodplain of the Upper Paraná*** found a greater difference in ^(δ13)c values of POM between sampling points than between seasons,indicating that the composition of regional sources influences the composition of POM more than dry and rainy *** addition,the concentration of chlorophyll during the dry season was positively correlated with ^(δ13)c values during that rainy ***,we found a relationship between factors limiting the growth of phytoplankton and ^(δ13)c values of POM,such as phosphate ions,indicating that variables that regulate phytoplankton growth tend to influence the composition of POM in river ***,maintaining the variables that regulate the phytoplankton community is of fundamental importance for the composition of POM,an important energy source in aquatic environments.

关键词： freshwater wetland stable isotopes food web subtropical environment

Effect of Aspergillus niger prolyl endopeptidase in patients with celiac disease on a long-term gluten-free diet

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World Journal of Gastroenterology 2024年第11期30卷 1545-1555页

作者： Juan Pablo Stefanolo Verónica Segura Martina Grizzuti Abel heredia Isabel comino Ana Florencia costa Roberto Puebla María Paz Temprano Sonia Isabel Niveloni Gabriel de Diego María E Oregui Edgardo gustavo Smecuol Mauricio c de Marzi Elena F Verdú carolina Sousa Julio césar Bai Small Bowel Section Department of MedicineGastroenterology Hospital of Buenos Aires“Dr.C.Bonorino Udaondo”Buenos Aires 1264Argentina Department of Microbiology and Parasitology Faculty of PharmacyUniversity of SevilleSeville 41080Spain Department of Medicine Dr.C.Bonorino Udaondo Gastroenterology HospitalBuenos Aires 1264Argentina Basic and Applied Research Group in Immunology and Bioactives(GIBAIB) Institute of Ecology and Sustainable Development(INEDES)National University of LujanLuján 6700Buenos AiresArgentina Department of Medicine Farncombe Family Digestive Health Research InstituteMcMaster UniversityHamilton L8S 4L8OntarioCanada Facultad de Medicina Universidad del SalvadorBuenos Aires C1051ABBArgentina

BAcKGROUND The gluten-free diet(GFD)has limitations,and there is intense research in the development of adjuvant *** To examine the effects of orally administered Aspergillus niger prolyl endopeptidase protease(AN-PEP)on inadvertent gluten exposure and symptom prevention in adult celiac disease(ceD)patients following their usual *** This was an exploratory,double-blind,randomized,placebo-controlled trial that enrolled ceD patients on a long-term *** a 4-wk run-in period,patients were randomized to 4 wk of two AN-PEP capsules(GliadinX;AVI Research,LLc,United States)at each of three meals per day or *** endpoints were:(1)Average weekly stool gluten immunogenic peptides(GIP)between the run-in and end of treatments and between AN-PEP and placebo;(2)celiac symptom index(cSI);(3)ceD-specific serology;and(4)quality of *** samples were collected for GIP testing by ELISA every Tuesday and Friday during run-ins and *** Forty patients were randomized for the intention-to-treat analysis,and three were excluded from the per-protocol ***,628/640(98.1%)stool samples were *** was undetectable(ces between treatment arms were *** 0.5%of samples had GIP concentrations sufficiently high(>0.32μg/g)to potentially cause mucosal *** GIP concentration in the AN-PEP arm was 44.7%lower than in the run-in ***-third of patients exhibiting GIP>0.08μg/g during run-in had lower or undetectable GIP after AN-PEP *** with the run-in period,the proportion of symptomatic patients(cSI>38)in the AN-PEP arm was significantly lower(Pchanges in specific *** This exploratory study conducted in a real-life setting revealed high adherence to the *** AN-PEP treatment did not significantly reduce the overall GIP stool ***,given the observation of a significantly lower prevale

关键词： celiac disease Aspergillus niger prolyl endoprotease Gluten immunogenic peptides Trial Symptoms Real-life trial

Nutrient restriction-activated Fra-2 promotes tumor progression via IGF1R in miR-15a downmodulated pancreatic ductal adenocarcinoma

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Signal Transduction and Targeted Therapy 2024年第3期9卷 1132-1146页

作者： Gian Luca Rampioni Vinciguerra Marina capece Luca Reggiani Bonetti Giovanni Nigita Federica calore Sydney Rentsch Paolo Magistri Roberto Ballarin Fabrizio Di Benedetto Rosario Distefano Roberto cirombella Andrea Vecchione Barbara Belletti gustavo Baldassarre Francesca Lovat carlo M.croce Department of cancer Biology and Genetics and comprehensive cancer center The Ohio State UniversityColumbus 43210 OHUSA Department of clinical and Molecular Medicine Faculty of Medicine and PsychologySant’Andrea HospitalUniversity of Rome“Sapienza”Rome 00189Italy Department of Diagnostic Clinic and Public Health MedicineUniversity of Modena and Reggio EmiliaModena 41100Italy hepato-pancreato-biliary Surgery and Liver Transplantation Unit University of Modena and Reggio EmiliaModena 41100Italy Division of Molecular Oncology Centro di Riferimento Oncologico di Aviano(CRO)Istituto di Ricovero e Cura a Carattere Scientifico(IRCCS)National Cancer InstituteAviano 33081Italy

Pancreatic ductal adenocarcinoma(PDAc)is a lethal disease,characterized by an intense desmoplastic reaction that compresses blood vessels and limits nutrient *** aggressiveness largely relies on its extraordinary capability to thrive and progress in a challenging tumor *** of the onco-suppressor miR-15a has been extensively documented in ***,we identified the transcription factor Fos-related antigen-2(Fra-2)as a miR-15a target mediating the adaptive mechanism of PDAc to nutrient *** report that the IGF1 signaling pathway was enhanced in nutrient deprived PDAc cells and that Fra-2 and IGF1R were significantly overexpressed in miR-15a downmodulated PDAc ***,we discovered that miR-15a repressed IGF1R expression via Fra-2 *** miR-15a-low context,IGF1R hyperactivated mTOR,modulated the autophagic flux and sustained PDAc growth in nutrient *** a genetic mouse model,Mir15aKO PDAc showed Fra-2 and Igf1r upregulation and mTOR activation in response to diet ***,nutrient restriction improved the efficacy of IGF1R inhibition in a Fra-2 dependent ***,our results point to a crucial role of Fra-2 in the cellular stress response due to nutrient restriction typical of pancreatic cancer and support IGF1R as a promising and vulnerable target in miR-15a downmodulated PDAc.

关键词： IGF1R Fra miR

What to Eat:Evidence for Selective Autophagy in Plants

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Journal of Integrative Plant Biology 2012年第11期54卷 907-920页

作者： Brice E.Floyd Stephanie c.Morriss gustavo c.MacIntosh Diane c.Bassham Department of Genetics Development and Cell BiologyIowa State UniversityAmes IA 50011USA Department of Biochemistry Biophysics and Molecular BiologyIowa State UniversityAmes IAUSA

Autophagy is a macromolecular degradation pathway by which cells recycle their contents as a developmental process, housekeeping mechanism, and response to environmental stress. In plants, autophagy involves the sequestration of cargo to be degraded, transport to the cell vacuole in a doublemembrane bound autophagosome, and subsequent degradation by lytic enzymes.

关键词： Autophagy degradation stress vacuole.

Molecular modeling of the octacoordinated tetracarbonato-Nd(III), [Nd(cO_3)_4]^(5-), complex and its nonacoordinated fluoro- and aquo-adducts

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Journal of Rare Earths 2010年第6期28卷 847-853页

作者： S. P. Sinha Alfredo M. Simas gustavo L. c. Moura Scientific Research & Development Departamento de Quimica Fundamental CCEN Universidade Federal de Pernambuco

Theoretical investigation on the structures of the octacoordinated [Nd(cO3)4]5-and the nonacoordinated [Nd(cO3)***2]5-complexes, using the SPARKLE parameters of the lanthanides within MOPAc, revealed that they possessed dodecahedral and square antiprismatic structures respectively with an average Nd-O distance of 0.249 nm. These structures and the Nd-O distances agreed well with those experimentally found in the crystal structures. Replacing the water molecule with a fluoride ion or a mondentatecarbonato ligand resulted in a nonacoordinated distorted square antiprismatic structures where the trans-carbonato groups were twisted. The corresponding decacoordinated structures with two fluoride ions or a bidentatecarbonato group, [Nd(cO3)4·F2]7-and [Nd(cO3)5]7-, were also investigated. In both cases considerable twisting of the transcarbonato groups was observed.

关键词： lanthanides theoretical molecular models octacoordination carbonato complexes adducts MOPAc SPARKLE rare earths