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Sessile serrated adenomas:Demographic,endoscopic and pathological characteristics

World Journal of Gastroenterology 2010年第27期16卷 3402-3405页

作者： Suryakanth R gurudu Russell I Heigh Giovanni De Petris Evelyn G Heigh Jonathan A Leighton Shabana F Pasha Isaac B Malagon Ananya Das Division of Gastroenterology Mayo Clinic ArizonaScottsdaleAZ 85259United States Department of Pathology Mayo Clinic ArizonaAZ 85259United States Department of Kinesiology Arizona State University

AIM:To study the demographic and endoscopic characteristics of patients with sessile serrated adenoma(SSA) in a single ***:Patients with SSA were identified by review of the pathology database of Mayo Clinic Arizona from 2005 to 2007.A retrospective chart review was performed to extract data on demographics,polyp characteristics,presence of synchronous adenomatous polyps or cancer,polypectomy methods,and related ***:One hundred and seventy-one(2.9%) of all patients undergoing colonoscopy had a total of 226 *** mean(SE) size of the SSAs was 8.1(0.4) mm;42% of SSAs were ≤ 5 mm,and 69% were ≤ 9 ***-one per cent of SSAs were located in the cecum or ascending *** half of the patients had synchronous polyps of other histological types,including hyperplastic and adenomatous *** adenocarcinoma was present in seven(4%) ***-seven percent of polyps were removed by ***:Among patients with colon polyps,2.9% were found to have *** of the SSAs were located in the right side and were safely managed by colonoscopy.

关键词： Sessile serrated polyp Sessile serrated adenoma Colonoscopy

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Anaplastic Large Cell Lymphoma, ALK-Negative Presenting in the Rectum: A Case Report and Review of the Literature

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Open Journal of Pathology 2013年第1期3卷 37-40页

作者： Komal Galani Suryakanth R. gurudu Longwen Chen Katalin Kelemen Department of Gastroenterology Mayo Clinic Phoenix USA Department of Laboratory Medicine and Pathology Mayo Clinic Phoenix USA Super Religare Laboratories Nagpur India

ALK-negative anaplastic large cell lymphoma (ALCL, ALK-) is a CD30+ T-cell neoplasm composed of large lymphoid cells with abundant cytoplasm and pleomorphic nuclei that lacks expression of ALK protein. We describe a case of ALCL, ALK-with primary involvement of the rectum in a 37 year old man, where the original diagnosis was established based on a colonoscopic biopsy. T-cell lymphomas are rare in the colorectal area and besides ALCL, their differential diagnosis includes enteropathic T-cell lymphoma, peripheral T-cell lymphoma, not otherwise specified, NK/T cell lymphoma, or NK-cell enteropathy. In addition, syncytial variant of classical Hodgkin lymphoma or a pleomorphic CD30-positive diffuse large B-cell lymphoma should also be ruled out. We discuss pitfalls of the differential diagnosis and review the literature of anaplastic large cell lymphoma in the gastrointestinal tract. Correct diagnosis of ALCL in the colon is important to avoid a colorectal surgery for an assumed adenocarcinoma, and to open the possibility for lymphoma-directed chemotherapy.

关键词： Anaplastic Large Cell Lymphoma CD30+ Lymphoma Gastrointestinal Lymphoma

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内镜在隐源性消化道出血中的作用

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传染病网络动态 2006年第11期 28-31页

作者： Suryakanth R. gurudu 李冰（编译）杨露绮（审校）

隐源性消化道出血（OGLB）的定义是包括结肠镜和／或胃镜（食管胃十二指肠镜检[EGD]）在内最初的阴性内镜结果之后持续或反复的不明原因出血。OGIB可以分为2类：（1）隐性OGIB，主要表现为反复性缺铁性贫血和／或反复性大便潜血阳性（F... 详细信息

隐源性消化道出血（OGLB）的定义是包括结肠镜和／或胃镜（食管胃十二指肠镜检[EGD]）在内最初的阴性内镜结果之后持续或反复的不明原因出血。OGIB可以分为2类：（1）隐性OGIB，主要表现为反复性缺铁性贫血和／或反复性大便潜血阳性（FOBT）；（2）显性OGIB：主要表现为黑便或便血。

关键词：隐源性消化道出血内镜不明原因出血十二指肠镜检缺铁性贫血反复性大便潜血食管胃

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Quality monitoring in colonoscopy: Time to act

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World Journal of Gastrointestinal Endoscopy 2015年第4期7卷 328-335页

作者： Mary A Atia Francisco C Ramirez Suryakanth R gurudu Division of Gastroenterology and Hepatology Mayo Clinic Arizona

Colonoscopy is the gold standard test for colorectal cancer screening. The primary advantage of colonoscopy as opposed to other screening modalities is the ability to provide therapy by removal of precancerous lesions at the time of detection. However, colonoscopy may miss clinically important neoplastic polyps. The value of colonoscopy in reducing incidence of colorectal cancer is dependent on many factors including, the patient, provider, and facility level. A high quality examination includes adequate bowel preparation, optimal colonoscopy technique, meticulous inspection during withdrawal, identification of subtle flat lesions, and complete polypectomy. Considerable variation among institutions and endoscopists has been reported in the literature. In attempt to diminish this disparity, various approaches have been advocated to improve the quality of colonoscopy. The overall impact of these interventions is not yet well defined. Implementing optimal education and training and subsequently analyzing the impact of these endeavors in improvement of quality will be essential to augment the utility of colonoscopy for the prevention of colorectal cancer.

关键词： Colonoscopy Quality improvement Cecalintubation rate Adenoma detection rate

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