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Efficacy of Qiancao(Radix Rubiae Cordifoliae) and Haipiaoxiao(Endoconcha Sepiellae), a traditional Chinese herb pair, on abnormal uterine bleeding in rats with incomplete abortion

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Journal of Traditional Chinese Medicine 2022年第5期42卷 758-763页

作者： ZHANG Tiantian li guowen CHU Zhifeng li Jie YU lijun GAO Yuan WANG Huifeng Department of Pharmacy Shanghai Songjiang Fangta Hospital of TCMShanghai 201600China Department of Pharmacy Shanghai TCM-Integrated HospitalShanghai 200080China Department of Traditional Chinese Medicine Shanghai Songjiang Fangta Hospital of TCMShanghai 201600China

OBJECTIVE: To investigate the most effective weight ratio of Qiancao(Radix Rubiae Cordifoliae) and Haipiaoxiao(Endoconcha Sepiellae) used to produce decoction for the treatment of abnormal uterine bleeding(AUB) in rats with incomplete abortion, and to study the possible mechanism. METHODS: The models of AUB were established by incomplete drug abortion with mifepristone and misoprostol in pregnant rats. The therapeutic effects of decoctions made by eight different weight ratios of Qiancao(Radix Rubiae Cordifoliae) and Haipiaoxiao(Endoconcha Sepiellae) were observed. RESULTS: Statistical analysis revealed that the most effective weight ratio of Qiancao(Radix Rubiae Cordifoliae) and Haipiaoxiao(Endoconcha Sepiellae) to treat AUB in this study was 2∶1. CONCLUSION: The insights gained from this study would improve understanding of the mechanisms involved in the effect of Qiancao(Radix Rubiae Cordifoliae) and Haipiaoxiao(Endoconcha Sepiellae) on AUB.

关键词： uterine hemorrhage Qiancao(Radix Rubiae Cordifoliae) Haipiaoxiao(Endoconcha Sepiellae) herb pair weight ratio

Experimental study of separation of ammonia synthesis vent gas by hydrate formation

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Petroleum Science 2009年第2期6卷 188-193页

作者： Dong Taibin Wang Leiyan liu Aixian Guo Xuqiang Ma Qinglan li guowen Sun Qiang State Key Laboratory of Heavy Oil Processing China University of Petroleum Beijing 102249 China

Termodynamic data on methane hydrate formation in the presence of ammonia are very important for upgrading of ammonia synthesis vent gas using hydrate formation. This paper is focused on the formation conditions of methane hydrate in the presence of ammonia and the effects of gas-liquid ratio and temperature on the separation of vent gas by hydrate formation. Equilibrium data for methane hydrate within an ammonia mole concentration range from 1% to 5 % were obtained. The experimental results indicated that ammonia has an inhibitive effect on hydrate formation. The higher the ammonia concentration, the higher is the pressure reguired for methane hydrate formation would be. The primary experimental results showed that when volume ratio of gas to liquid was 80：1 and temperature was 283.15 K, total mole fraction of （H2＋N2） in gas phase could reach 96.9 %.

关键词： CH4 hydrate ammonia THF thermodynamics separation

Small Things Create Big Waves

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China Today 2024年第1期73卷 32-36页

作者： li guowen 不详

With the help of governments at all levels,farmers and herdsmen in Tibet can now continually keep up with the progress of the times and social development through their own efforts.“Convenient facilities and relatively stable incomes are making our life increasingly promising,”enthused Yangjen Lhamo,who lives in Naxingtang Community,Nagqu City,Tibet Autonomous *** believes that her children’s life will be better.

关键词： Create Tibet own

The effects of pH, surfactant, ion concentration,coformer, and molecular arrangement on the solubility behavior of myricetin cocrystals

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Acta Pharmaceutica Sinica B 2019年第1期9卷 59-73页

作者： Shuzhen Ren Mingyu liu Chao Hong guowen li Jiabin Sun Jianying Wang Lei Zhang Yan Xie Research Center for Health and Nutrition Shanghai University of Traditional Chinese Medicine Institute of Chinese Materia Medica Shanghai University of Traditional Chinese Medicine Pharmacy Department Shanghai TCM-Integrated Hospital Shanghai University of Traditional Chinese Medicine Shanghai Innovation Center of TCM Health Service Shanghai University of Traditional Chinese Medicine

Pharmaceutical cocrystals are a promising technology that can be used to improve the solubility of poor aqueous compounds. The objective of this study was to systematically investigate the solubility of myricetin(MYR) cocrystals, including their kinetic solubility, thermodynamic solubility, and intrinsic dissolution rate(IDR). The effects of pH, surfactant, ion concentration, and coformers on the cocrystal solubility were evaluated. Furthermore, single crystal structures of MYR, myricetin–isonicotinamide(MYR–INM) and myricetin–caffeine(MYR–CAF) cocrystals were analyzed to discuss the possible reasons for the enhancement of cocrystal solubility from the perspective of the spatial *** results indicated that the kinetic solubility of MYR cocrystals was modulated by pH and cocrystal coformer(CCF) ionization in buffer solution, while it primarily depended on the CCF solubility in pure water. In addition, the solubility of MYR cocrystals was increased in a concentration dependent fashion by the surfactant or ion concentration. The thermodynamic solubility of MYR–INM(1:3) cocrystals decreased with the increases of the pH value of the dissolution media. The IDR of MYR cocrystals was faster than that of MYR in the same medium and extremely fast in pH 4.5 buffer. The improved solubility of MYR cocrystals was probably related to the alternate arrangements of MYR and INM/CAF molecules and increased intermolecular distance. The present study provides some references to investigate the solubility behavior of pharmaceutical cocrystals.

关键词： Cocrystal solubility Myricetin pH Coformer Crystal structure

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Design Tibet

Building an Eco-Chain Within an Industrial Park

China Today 2015年第9期 70-71页

作者： li guowen

IT was early spring when I first met Dainqoi,a professor at the School of Art of Tibet University,at the new campus on the eastern side of *** sunlight shone through the abundant trees,creating a pleasant *** School life Dainqoi was born in *** parents are Lhasa natives."When my parents were younger,Lhasa was a small city with a population of 20,000to 30,000 living around the Jokhang Temple,"Dainqoi said."It was a society（共2页)

关键词： School Ti Design Tibet

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China Today 2006年第2期55卷 14-15页

作者： li guowen

SINCE 2004, Chinese experts and governments at various levels have been actively promoting the development of a recyclable economy. Those involved agree that the eco-industrial park model has so far been most effectiv... 详细信息

关键词：中国循环经济清洁能源经济增长工业园

Heart-to-heart Exchanges Make for Lasting Friendships

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China Today 2018年第7期67卷 20-22页

作者： li guowen 不详

THE Shanghai Cooperation Organization(SCO)has eight member states,four observer states,and six dialogue partners,which in total cover a vast expanse of the planet’s landmass with diverse cultures,ethnic groups,langua... 详细信息

关键词： SCO Heart-to-heart Exchanges Make for Lasting Friendships

Twin Meetings Frank on Problems and Challenges

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China Today 2013年第4期62卷 24-27页

作者： li guowen 不详

THE government report delivered by the Chinese premier is invariably a key event in the annual meeting of the National People’s Congress(NPC).The NPC session overlaps with the yearly meeting of the Chinese People’s ... 详细信息

关键词： ECONOMIC development CORRUPTION ENVIRONMENTAL degradation POWER (Social sciences) MONOPOliES CHINA

Tourism Expands Tibet’s Economic Development

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China Today 2015年第4期64卷 63-64页

作者： li guowen 不详

LAST April,I attended a lecture on Tibet’s tourism culture and economic development by Professor Thubten Kredrup at the University of Tibet.I recently met him again at the Scientific Research Office of the university.

关键词： Tourism Expands Tibet’s Economic Development