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Advances in Graphene‑Based Electrode for Triboelectric Nanogenerator

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Nano-Micro Letters 2025年第1期17卷 378-403页

作者： Bin Xie Yuanhui guo Yun Chen Hao zhang Jiawei Xiao Maoxiang Hou Huilong Liu Li Ma Xin Chen Chingping Wong State Key Laboratory of Precision Electronic Manufacturing Technology and Equipment Guangdong University of TechnologyGuangzhou 510006People’s Republic of China School of Electromechanical Engineering Guangdong University of TechnologyGuangzhou 510006People’s Republic of China School of Materials Science and Engineering Georgia Institute of TechnologyAtlantaGA 30332USA

With the continuous development of wearable electronics,wireless sensor networks and other micro-electronic devices,there is an increasingly urgent need for miniature,flexible and efficient nanopower generation *** nanogenerator(TENG)technology can convert small mechanical energy into electricity,which is expected to address this *** the core component of TENG,the choice of electrode materials significantly affects its *** metal electrode materials often suffer from problems such as durability,which limits the further application of ***,as a novel electrode material,shows excellent prospects for application in TENG owing to its unique structure and excellent electrical *** review systematically summarizes the recent research progress and application prospects of TENGs based on graphene *** precision processing methods of graphene electrodes are introduced,and the applications of graphene electrode-based TENGs in various scenarios as well as the enhancement of graphene electrodes for TENG performance are *** addition,the future development of graphene electrode-based TENGs is also prospectively discussed,aiming to promote the continuous advancement of graphene electrode-based TENGs.

关键词： Triboelectric nanogenerator Precision processing Graphene electrode Self-powered sensor

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植物抗真菌基因工程研究进展

山东农业大学学报（自然科学版） 2003年第1期34卷 148-151页

作者：于金凤张修国张天宇山东农业大学农学院山东泰安271018 植物保护学院山东泰安271018

近几年来 ,由于分子生物学和生物工程技术的迅速发展 ,尤其是重组DNA技术的发展 ,开辟了植物抗病育种的新途径。植物抗病机制的分子生物学和抗病基因工程的研究有了许多新的突破。

关键词：植物抗真菌基因工程抗病育种抗病机制分子生物学基因对基因假说

Integrating lipidomics and gut microbiota to study the anti-hyperlipidemia effect of Sargentodoxae Caulis extract

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Traditional Medicine Research 2025年第1期10卷 1-11页

作者： Xiao-Xiao zhang Li Jia xiu-Jun Zhan Charity Ngina Qing-Rui zhang Xiao-Ge Li Qi-Bao Jiang Shi Bai Miao-Miao Jiang National Key Laboratory of Chinese Medicine Modernization Tianjin University of Traditional Chinese MedicineTianjin 301617China Haihe Laboratory of Modern Chinese Medicine Tianjin 301617China School of Medicine Taizhou UniversityTaizhou 318000China.

Background:Sargentodoxae Caulis(SC)is the vine stem of Sargentodoxa Cuneata(Oliv.)Rehd.&*** in ***,and it in traditional Chinese medicine has been known for promoting blood circulation and removing blood stasis as recorded in the ancient book“Illustrated Classics of Materia Medica”.It has been used effectively to treat blood stasis too in modern clinical ***,the anti-hyperlipidemia effect of SC is not fully *** paper aims at exploring the use of SC stems to improve the balance of blood lipids in the body,and its new role in treating ***:The effects of SC extract on hyperlipidemia were explored by combining lipidomics and gut ***,we explored the potential mechanism of SC in treating hyperlipidemia by pathway ***:The results showed that the stem extract of SC could restore the physiological and biochemical indices of hyperlipidemia in mice,as well as repair the morphological and structural damage to *** to the Model group,the SC extract significantly reduced the liver index,epididymal fat index,and Lee’s *** also significantly decreased serum levels of total cholesterol,triglycerides,low-density lipoprotein cholesterol,peroxisome proliferator-activated receptor gamma(PPAR-γ),D-lactate,and free fatty acids,while significantly increasing the relative content of peroxisome proliferator-activated receptor alpha(PPAR-α).These changes were statistically ***-targeted lipidomics,based on LC-MS,were utilized to investigate the lipid metabolism characteristics in serum,liver,and epididymal fat of the *** was observed that,compared to the blank group,the Model group exhibited significant changes primarily in glycerol lipids and *** treatment group also displayed alterations in these lipids.A total of 38,81,and 27 differential lipids were identified in serum,liver,and epididymal fat samples,*** these,14 common differenti

关键词： hyperlipidemia Sargentodoxae Caulis lipidomics intestinal flora

血浆β淀粉样蛋白在阿尔茨海默病早期诊断中的临床价值

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标记免疫分析与临床 2017年第9期24卷 976-978页

作者：王治国战莹武晓丹郭佳陆国秀张彤张国旭沈阳军区总医院核医学科辽宁沈阳110016

目的探究血浆Aβ42、Aβ40和Aβ42/Aβ40比值作为生物标志物在阿尔茨海默病和轻度认知障碍早期诊断中的价值。方法入选受试者113例,其中44例阿尔茨海默病患者,33例轻度认知障碍患者和36例正常老年人,取静脉血测定其血浆Aβ42和Aβ40蛋... 详细信息

目的探究血浆Aβ42、Aβ40和Aβ42/Aβ40比值作为生物标志物在阿尔茨海默病和轻度认知障碍早期诊断中的价值。方法入选受试者113例,其中44例阿尔茨海默病患者,33例轻度认知障碍患者和36例正常老年人,取静脉血测定其血浆Aβ42和Aβ40蛋白水平。结果 NC组、MCI组和AD组Aβ42水平和Aβ42/Aβ40比值逐渐下降。Aβ40水平逐渐升高,但差异无统计学意义。Aβ42水平可以区分NC组和AD组,但无法区分MCI组。Aβ40水平在各组之间比较差异无统计学意义。Aβ42/Aβ40比值在各组之间差异均具有统计学意义。结论血浆Aβ42和Aβ40不能独立作为阿尔茨海默病早期诊断标志物,而它们的比值或许可以作为潜在的MCI和AD的诊断生物标志物,作为脑脊液检查和影像学检查的补充作用。

关键词：阿尔茨海默病轻度认知障碍淀粉样蛋白 Aβ42 Aβ40

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习近平文化思想的创新性理论

新疆师范大学学报（哲学社会科学版） 2025年第1期46卷 7-15,F0002页

作者：张国祚湖南大学中国文化软实力研究中心湖南大学马克思主义学院湖南长沙410012

习近平文化思想是对马克思主义经典作家文化理论的继承、丰富和发展,是对中华优秀传统文化的创造性转化和创新性发展,是中国化时代化的马克思主义文化理论的最新成果,使马克思主义文化理论达到新高度。习近平文化思想的新成果、新高度... 详细信息

习近平文化思想是对马克思主义经典作家文化理论的继承、丰富和发展,是对中华优秀传统文化的创造性转化和创新性发展,是中国化时代化的马克思主义文化理论的最新成果,使马克思主义文化理论达到新高度。习近平文化思想的新成果、新高度充满理论创新性。文本认为,应从关于宣传思想文化工作战略定位的新概括,关于开辟马克思主义中国化时代化新境界必须遵循的原理,关于理论武装工作要在“真”与“化”上下功夫,关于明确意识形态建设的新重点,关于社会主义核心价值观的新阐发,关于文化自信的深刻阐发,关于文化建设必须遵循的原则,关于中华优秀传统文化的时代价值及其赓续的深刻阐发,关于提出构建中国特色哲学社会科学系统思想,关于新闻舆论工作意义、成效的重要论述,关于旗帜鲜明开展文艺批评的新论述,关于办好思政课的系统论述,关于精神文明建设的新坐标,关于人类文明互鉴的新倡议,关于网络文化建设的系统论述等方面理解习近平文化思想的理论创新。

关键词：习近平文化思想马克思主义中国化时代化文化自信创新性价值意蕴

Glucocorticoid receptor signaling in the brain and its involvement in cognitive function

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Neural Regeneration Research 2025年第9期20卷 2520-2537页

作者： Chonglin Su Taiqi Huang Meiyu zhang Yanyu zhang Yan Zeng Xingxing Chen Brain Science and Advanced Technology Institute Hubei Province Key Laboratory of Occupational Hazard Identification and ControlSchool of MedicineWuhan University of Science and TechnologyWuhanHubei ProvinceChina

The hypothalamic-pituitary-adrenal axis regulates the secretion of glucoco rticoids in response to environmental *** the brain,a nuclear receptor transcription fa ctor,the glucocorticoid recepto r,is an important component of the hypothalamicpituitary-a d renal axis's negative feedback loop and plays a key role in regulating cognitive equilibrium and *** glucoco rticoid receptor influences cognitive processes,including glutamate neurotransmission,calcium signaling,and the activation of brain-derived neurotrophic factor-mediated pathways,through a combination of genomic and non-genomic *** interactions within the central nervous system can alter the expression and activity of the glucocorticoid receptor,there by affecting the hypothalamic-pituitary-a d renal axis and stress-related cognitive *** appropriate level of glucocorticoid receptor expression can improve cognitive function,while excessive glucocorticoid receptors or long-term exposure to glucoco rticoids may lead to cognitive *** with cognitive impairment-associated diseases,such as Alzheimer's disease,aging,depression,Parkinson's disease,Huntington's disease,stroke,and addiction,often present with dysregulation of the hypothalamic-pituitary-adrenal axis and glucocorticoid receptor *** review provides a comprehensive overview of the functions of the glucoco rticoid receptor in the hypothalamic-pituitary-a d renal axis and cognitive *** emphasizes that appropriate glucocorticoid receptor signaling fa cilitates learning and memory,while its dysregulation can lead to cognitive *** provides clues about how glucocorticoid receptor signaling can be targeted to ove rcome cognitive disability-related disorders.

关键词： brain-derived neurotrophic factor calcium signaling glucocorticoid receptor glucocorticoid glutamate transmission hypothalamic-pituitary-adrenal axis long-term potentiation neurocognitive disorders neuroplasticity stress

A new method for direct synthesis of Li2CO3 powders by membrane electrolysis

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Rare Metals 2018年第8期37卷 716-722页

作者： Xi-Juan Pan Ting-An zhang Zhi-He Dou guo-Zhi Lyu xiu-xiu Han Jun-Jie zhang School of Metallurgy Northeastern University Shenyang 110819 China Key Laboratory of Ecological Metallurgy of Multi-metal Intergrown Ores of Education Ministry Shenyang 110819China

A new method for the direct synthesis of Li2CO3 powders by membrane electrolysis from LiC1 solution is demonstrated in this paper, where a novel electrolysis system combining ventilation, agitation and loop filtration functions was reported. The aim of this work is to explore the effect of the starting concentration of LiC1 on the phase and micromorphology of Li2CO3 crystals and thereafter to explore the mechanism of crystallization and grain growth law. Scanning electron microscopy （SEM） images indicate that the particles become irregular polycrystalline from well-defined flower-like and the micro-crystals change from lamellar to needle-like and subsequently to smaller globular granules, and the surface of the crystals becomes smooth with LiC1 concentration increasing from 50 to 400 g.L^-3. The crystalline phases of the different samples were characterized using powder X-ray diffraction （XRD） and the results prove that pure LiaCO3 crystals can be obtained in a single step by the electrolysis method. The particle size distributions show that both volume mean crystal sizes and the full width at half maximum （FWHM） decrease when the starting LiC1 concentration increases from 50 to 300 g.L 3 and also decreases from 400 to 300 g-L^-3.

关键词： Lithium carbonate Lithium chloride Membrane electrolysis Carbon dioxide

降钙素原检测应用于肺癌化疗后肺部感染患者的临床意义

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中国实验诊断学 2016年第11期20卷 1895-1897页

作者：陈建国谷秀梅张静吴白平湖南省肿瘤医院检验科湖南长沙410013

目的探究肺癌化疗后肺部感染患者降钙素原检测的临床意义。方法我院2015年1月-2015年12月收治的肺癌化疗患者100例,依据是否发生肺部感染分为观察组和对照组,每组50例。感染组患者在发生肺部感染24h内、治疗后3d、治疗后7d检测血清降钙... 详细信息

目的探究肺癌化疗后肺部感染患者降钙素原检测的临床意义。方法我院2015年1月-2015年12月收治的肺癌化疗患者100例,依据是否发生肺部感染分为观察组和对照组,每组50例。感染组患者在发生肺部感染24h内、治疗后3d、治疗后7d检测血清降钙素原浓度、C反应蛋白浓度和白细胞数量。比较两组患者降钙素原阳性例数和平均降钙素原浓度,比较感染组患者治疗前后降钙素原浓度、C反应蛋白浓度和白细胞数量。结果与对照组相比,感染组降钙素原阳性例数明显增加,平均降钙素原浓度明显升高(P<0.05)。感染组患者治疗后3天与治疗后7天降钙素原浓度、C反应蛋白浓度和白细胞数量均逐渐减小(P<0.05)。结论血清降钙素原可以作为肺癌术后肺部感染患者的辅助诊断指标。监测血清降钙素原浓度有利于预测患者的病情与预后。

关键词：肺部感染降钙素原 C反应蛋白

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大肠癌临床表现的多样性及其误诊

胃肠病学 1997年第2期2卷 79-81页

作者：潘国宗张秀兰中国医学科学院中国协和医科大学北京协和医院 100730 北京市公安医院内科 10006

本文报道1970年1月至1995年12月在北京协和医院经手术病理确诊的791例大肠癌,其中结肠癌396例,直肠癌395例,年龄20～85岁,平均54.4岁。分析结果提示:(1)本组大肠癌手术病例逐年增多。(2)Duke A、B期占36％,C、D期平均误诊时间比A、B期长... 详细信息

本文报道1970年1月至1995年12月在北京协和医院经手术病理确诊的791例大肠癌,其中结肠癌396例,直肠癌395例,年龄20～85岁,平均54.4岁。分析结果提示:(1)本组大肠癌手术病例逐年增多。(2)Duke A、B期占36％,C、D期平均误诊时间比A、B期长3个月。(3)以粘液血便,便鲜血、腹痛伴包块,首发贫血及间断发烧为临床重要表现,分别占大肠癌的15.3％、10.2％、7.6％、5.4％及2.0％。这些病人一度被误诊为菌痢、内痔、急慢性肠梗阻、贫血或肠结核等。(4)7cm以下的直畅癌占42.2％,其有75.1％的患者却未做肛门指诊,是误诊的重要原因之一。(5)粪潜血试验阳性率为84％,可作为筛查的一种手段。

关键词：大肠癌粪潜血试验肛门指诊