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Biomedical and Environmental Sciences 2024年第4期37卷 432-435页

作者： XIA Xian li guo ming TANG Yi WANG Si Quan HE Fei JIANG Yong Zhong YANG Hong Mei JIANG Hong lin LYU Jing MAO ling Feng Hubei Key Laboratory of Edible Wild Plants Conservation&Utilization Hubei Normal UniversityHuangshi 430070HubeiChina Hubei Provincial Center for Disease Control and Prevention Wuhan 430079HubeiChina Joint Research Center for Molecular Diagnosis of Severe Infection in Children Binjiang Institute of Zhejiang UniversityHangzhou 310058ZhejiangChina

Pertussis is an acute and highly contagious respiratory disease caused by Bordetella pertussis(***),which occurs in people of all ages and is most dangerous for young children,especially *** introduction of whole-cell pertussis vaccines(wPVs)in the 1950s dramatically reduced the incidence of pertussis worldwide[1].However,over the past two decades,many studies have reported the resurgence of pertussis in different countries[2].Epidemiological surveillance in Hubei Province over the last 3 years revealed a clear increasing trend in the incidence of pertussis during the coronavirus disease 2019(COVID-19)epidemic.

关键词： Pertussis dangerous Hubei

浅谈市政污水处理工程建设中存在的问题及解决措施

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建筑与装饰 2024年第5期 133-135页

作者：郭黎明陕西环保集团建筑工程有限公司陕西西安 710000

近些年,伴随着生态环境治理的高速发展,污水处理工程的数量和范畴也在不断增加.项目风险管理建设者既需要从整体的视角明确提出更为科学的改进措施,还要合理优化配置,防止对后续项目产生一定的影响.与此同时,管理者必须剖析以前工作上... 详细信息

近些年,伴随着生态环境治理的高速发展,污水处理工程的数量和范畴也在不断增加.项目风险管理建设者既需要从整体的视角明确提出更为科学的改进措施,还要合理优化配置,防止对后续项目产生一定的影响.与此同时,管理者必须剖析以前工作上存在的问题,明确指出更为科学的创新方案.本文讲述了污水处理工程建设和管理方面存在的问题、防范措施,以供参考.

关键词：污水处理工程管理建设管理应对建议

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市政工程施工中节能绿色环保技术的应用

新型装配式可调钢拱架在复杂地质上承式拱桥中的应用

建筑与装饰 2024年第3期 130-132页

作者：郭黎明陕西环保集团建筑工程有限公司陕西西安 710000

现阶段,随着社会经济的快速发展,城镇化进程的不断加快,人们生活水平越来越高,对生态环境保护问题也越来越重视.建筑工程管理人员应积极将节能绿色环保工程施工理念应用在工程施工建设中,不断创新并持续优化节能绿色环保技术,有效提升... 详细信息

现阶段,随着社会经济的快速发展,城镇化进程的不断加快,人们生活水平越来越高,对生态环境保护问题也越来越重视.建筑工程管理人员应积极将节能绿色环保工程施工理念应用在工程施工建设中,不断创新并持续优化节能绿色环保技术,有效提升工程施工质量.基于此,本文首先阐述了市政工程施工中应用节能绿色环保技术的重要性,其次对市政工程施工中节能绿色环保技术的应用进行详细探析,以供参考.

关键词：市政工程施工节能绿色环保技术应用

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建筑机械 2024年第6期 117-123页

作者：李国明郑燚中交城市建设(四川)有限公司四川成都611100

为解决传统“321桁架梁”、“六四式军用梁”等钢拱架施工风险高、拼装难度大、无法重复使用的缺陷,文章提出1套装配式可调钢拱架体系。可调钢拱架由基本节段与可调构造组成,其中可调构造包括跨径调节、幅宽调节与轴线调节构造,可适应... 详细信息

为解决传统“321桁架梁”、“六四式军用梁”等钢拱架施工风险高、拼装难度大、无法重复使用的缺陷,文章提出1套装配式可调钢拱架体系。可调钢拱架由基本节段与可调构造组成,其中可调构造包括跨径调节、幅宽调节与轴线调节构造,可适应不同特性的主拱圈施工,并基于Midas Civil软件验证了钢拱架的强度及稳定性。结果表明,装配式可调钢拱架整体强度、稳定性及调节螺杆强度均满足设计规范要求。结合大宁河大桥地质条件复杂、岩溶微发育、对拱架强度要求高的特性,研究了主拱圈施工、可调钢拱架安装、预压及拆除等施工关键技术。

关键词：可调钢拱架装配式上承式拱桥主拱圈钢拱架

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Breaking the final barrier in reproductive animal cloning: macaque monkeys cloned

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National Science Review 2018年第3期5卷 301-303页

作者： Hongjun Song guo-li ming Department of Neuroscience and Mahoney Institute for Neurosciences Department of Cell and Developmental Biology Institute for Regenerative Medicine University of Pennsylvania

Animal models are essential in research aiming to understand human biology and diseases,yet far too often clinical trials fail with drugs and therapeutic approaches that have been developed through,tested and built up... 详细信息

关键词： Breaking the final barrier in reproductive animal cloning macaque monkeys cloned

MapReduce Based Parallel Bayesian Network for Manufacturing Quality Control

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Chinese Journal of Mechanical Engineering 2017年第5期30卷 1216-1226页

作者： Mao-Kuan Zheng Xin-guo ming Xian-Yu Zhang guo-ming li School of Mechanical Engineering Shanghai Jiao Tong University

Increasing complexity of industrial products and manufacturing processes have challenged conventional statistics based quality management approaches in the cir- cumstances of dynamic production. A Bayesian network and big data analytics integrated approach for manufacturing process quality analysis and control is proposed. Based on Hadoop distributed architecture and MapReduce parallel computing model, big volume and variety quality related data generated during the manufacturing process could be dealt with. Artificial intelligent algorithms, including Bayesian network learning, classification and reasoning, are embedded into the Reduce process. Relying on the ability of the Bayesian network in dealing with dynamic and uncertain problem and the parallel computing power of MapReduce, Bayesian net- work of impact factors on quality are built based on prior probability distribution and modified with posterior probability distribution. A case study on hull segment manufacturing precision management for ship and offshore platform building shows that computing speed accelerates almost directly pro- portionally to the increase of computing nodes. It is also proved that the proposed model is feasible for locating and reasoning of root causes, forecasting of manufacturing outcome, and intelligent decision for precision problem solving. The inte- gration ofbigdata analytics and BN method offers a whole new perspective in manufacturing quality control.

关键词： Bayesian network Big data analytics MapReduce Quality control

Reprogram to pluripotency: a new logic and a chemical cocktail

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National Science Review 2014年第1期1卷 6-7页

作者： Hongjun Song guo-li ming Institute for Cell Engineering Departments of Neurology and Neuroscience Johns Hopkins University School of Medicine

Somatic cells rom animals and humans can be reprogrammed into pluripotent stem cells by pluripotency *** Deng and colleagues discovered that pluripotency can also be induced with exogenous lineage speciiers via balancing competing diferentiation *** a related study they achieved,for the irst time,restoration of pluripotency in adult somatic cells using a chemical cocktail alone.

关键词： GATA Reprogram to pluripotency a new logic and a chemical cocktail PSCs SOX

EFFECT OF DRILLPIPE ROTATION ON BOREHOLE CLEANING FOR EXTENDED REACH WELL

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Journal of Hydrodynamics 2009年第3期21卷 366-372页

作者： WANG Zhi-ming guo Xiao-le li ming HONG Yu-kui College of Oil and Gas Engineering China University of Petroleum Beijing 102249 China

Wellbore cleaning is a key technology for the Extended Reach Drilling （ERD）. The success of drilling extended reach wells depends directly upon the quality of wellbore cleaning. The rotation of the drillpipe, and hydraulic and rheological parameters, are the key factors for wellbore cleaning. In this study, Computational Fluid Dynamics （CFD） is applied to simulate solid-liquid two-phase flows in wellbore annulus. The annual flow field with the presence of drillpipe rotation is described through analyzing various rotation conditions. The results indicate that the quasi-spiral flow is the main flow pattern for liquid-solid transport in the horizontal annulus. The influence of rotation on the cuttings transport is also investigated, as the rotation of drillpipe increases the disturbance of liquid to solid in annulus. As a result, the solid flow becomes favorable and the solid volume is reduced. Comparisons with previously published results are also performed to prove the importance of drillpipe rotation in the wellbore clearing for the ERD.

关键词： Extended Reach Drilling (ERD) borehole cleaning solid-liquid two-phase flow drillpipe rotation simulation spiral flow

Synthesis, Crystal Structure and Biological Activity of 2-Chloro-N-{2-fluoro-5-[N-(phenylsulfonyl) phenyl-sulfonamido]phenyl}benzamide

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Chemical Research in Chinese Universities 2008年第3期24卷 295-298页

作者： li Wen-ming WANG Jian-guo li Zheng-ming SONG Hai-bin Elemento-Organic Chemistry Institute State Key Laboratory of Elemento-Organic Chemistry National Pesticide Engineering Research Center Nankai University Tianjin 300071 P R. China

2-Chloro-N-{2-fluoro-5-[N-（phenylsulfonyl）phenylsulfonamido]phenyl}benzamide was synthesized and its crystal structure was also determined by X-ray single-crystal diffraction. The title compound（C25H18ClFN2O5S2） belongs to monoclinic, space group P21/n with a=0.7377（3） nm, b=1.2036（5） nm, c=2.6846（11） nm, β=90.895（9）°, V=2.3833（16） nm3, Mr=544.98, Z=4, Dc=1.519 g/cm3, μ=0.385 mm–1, F（000）=1120, R1=0.0632, and wR2=0.1438. Its crystal structure belongs to a novel class that has not been reported yet, and its preliminary herbicidal activity was also tested. Its inhibition rate to seedling growth of barnyard grass reaches 15.1% at 100 μg/mL.

关键词： X-ray diffraction Crystal structure Synthesis Biological activity

The Cysteine Pairs in CLV2 are Not Necessary for Sensing the CLV3 Peptide in Shoot and Root Meristems

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Journal of Integrative Plant Biology 2010年第9期52卷 774-781页

作者： Xiufen Song Peng guo Chen li Chun-ming liu Key Laboratory of Photosynthesis and Environmental Molecular Physiology Institute of Botany Chinese Academy of Sciences Beijing 100093 China

Receptor-like proteins （RLPs） are involved in both plant defense and developmental processes. Previous genetic and biochemical studies show that the leucine-rich repeat （LRR） receptor-like protein CLAVATA2 （CLV2） functions together with CLAVATA1 （CLV1） and CORYNE （CRN） in Arabidopsis to limit the stem cell number in shoot apical meristem, while in root it acts with CRN to trigger a premature differentiation of the stem cells after sensing the exogenously applied peptides of CLV3p, CLE19p or CLE40p. It has been proposed that disulfide bonds might be formed through two cysteine pairs in the extracellular LRR domains of CLV1 and CLV2 to stabilize the receptor complex. Here we tested the hypothesis by replacing these cysteines with alanines and showed that depletions of one or both of the cysteine pairs do not hamper the function of CLV2 in SAM maintenance. In vitro peptide assay also showed that removal of the cysteine pairs did not affect the perception of CLV3 peptides in roots. These observations allow us to conclude that the formation of disulfide bonds is not needed for the function of CLV2.

关键词： CYSTEINE proteinases PEPTIDES PROTEINS ARABIDOPSIS STEM cells