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Morphological Mechanism and Experimental Verification of Self-healing of Basalt-fiber Modified Water-soaked Asphalt

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 171-186页

作者： XIAO Minmin DONG Jinyong LI Chunyan guo xu REN Jianguo School of Urban Construction and Safety Engineering Shanghai Institute of TechnologyShanghai 201418China

This study investigates the mechanism of action of representative molecules of basalt fibers on the healing of water-soaked *** parameters,morphological characteristics,interfacial healing energy,and interfacial healing strength were analyzed using molecular dynamics and macroscopic tests under different time,temperature,and water conditions to evaluate the specific states and critical conditions involved in *** results indicate that basalt-fiber molecules can induce rearrangement and a combination of water-soaked asphalt at the healing *** groups with different bonding states increase the interfacial adsorption capacity of water-soaked *** interaction between basalt fiber molecules and water molecules leads to a"hoop"phenomenon,while aromatics-2 molecules exhibit a"ring band aggregation"*** former reduces the miscibility of water and asphalt molecules,while the latter causes slow diffusion of the ***,a micro-macro dual-scale comparison of interfacial healing strength was conducted at temperatures of 297.15 and 312.15 K to identify the strength transition point and critical temperature of 299.4 K during the self-healing process of basalt-fiber modified water-soaked asphalt.

关键词： water-soaked asphalt basalt-fibers self-healing properties moisture status molecular characterization

Synthesis, Structural Characterization of TTM-TTF Intercalated with Lamellar MnPS3

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有机化学 2003年第Z1期23卷 260-260页

作者： ZHANG xuan CHEN Xing-guo fu Yang SU xu QIN Jin-Gui Department of Chemistry Wuhan University Wuhan 430072 Department of Chemistry Wuhan University Wuhan 430072 Department of Chemistry Wuhan University Wuhan 430072 Department of Chemistry Wuhan University Wuhan 430072 Department of Chemistry Wuhan University Wuhan 430072

　　Intercalation of organic species into layer inorganic solids provides a useful approach to creating ordered organ ic-inorganic nanocomposite materials with novel properties compared with the parent compounds, and hence has attracted much attention in recent years. [1] Clement and co-workers had reported that an organic electron donor TTF monocation intercalated into the MPS3 (M = Mn, Fe), and the intercalates exhibited much higher conductivity than the corresponding pure host compounds. Our group also synthesized the intercalation compound of BEDT-TTF into MnPS3, which exhibits the room temperature conductivity of 8.5 × 10-5 S/cm, 1O5 times higher than that of the pristine MnPS3 ( ＜ 10- 10 S/cm). [2]……

关键词： nanocomposite materials intercalation compound room temperature electron donor

Induced neural stem cells regulate microglial activation through Akt-mediated upregulation of CXCR4 and Crry in a mouse model of closed head injury

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Neural Regeneration Research 2025年第5期20卷 1416-1430页

作者： Mou Gao Qin Dong Dan Zou Zhijun Yang Lili guo Ruxiang xu Department of Neurosurgery Sichuan Academy of Medical Sciences and Sichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengduSichuan ProvinceChina Department of Neurosurgery Chinese PLA General HospitalBeijingChina Department of Neurology Fu Xing HospitalCapital Medical UniversityBeijingChina

Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and *** previously reported that induced neural stem cells can modulate the behavior of activated microglia via CXCL12/CXCR4 signaling,influencing their activation such that they can promote neurological ***,the mechanism of CXCR4 upregulation in induced neural stem cells remains *** this study,we found that nuclear factor-κB activation induced by closed head injury mouse serum in microglia promoted CXCL12 and tumor necrosis factor-αexpression but suppressed insulin-like growth factor-1 ***,recombinant complement receptor 2-conjugated Crry(CR2-Crry)reduced the effects of closed head injury mouse serum-induced nuclear factor-κB activation in microglia and the levels of activated microglia,CXCL12,and tumor necrosis factor-α.Additionally,we observed that,in response to stimulation(including stimulation by CXCL12 secreted by activated microglia),CXCR4 and Crry levels can be upregulated in induced neural stem cells via the interplay among CXCL12/CXCR4,Crry,and Akt signaling to modulate microglial *** agreement with these in vitro experimental results,we found that Akt activation enhanced the immunoregulatory effects of induced neural stem cell grafts on microglial activation,leading to the promotion of neurological recovery via insulin-like growth factor-1 secretion and the neuroprotective effects of induced neural stem cell grafts through CXCR4 and Crry upregulation in the injured cortices of closed head injury ***,these beneficial effects of Akt activation in induced neural stem cells were positively correlated with the therapeutic effects of induced neural stem cells on neuronal injury,cerebral edema,and neurological disorders post–closed head *** conclusion,our findings reveal that Akt activation may enhance the immunoregulatory effects of induced neura

关键词： Akt signaling cerebral edema closed head injury Crry CXCR4 induced neural stem cell microglia neuroinflammation

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中国大陆6级以上强震前的地震应变场研究

地球物理学报 2017年第10期60卷 3804-3814页

作者：杨明芝马禾青罗国富许晓庆宁夏地震局银川750001

以地震应变场作为地震活动的变量,通过自然正交函数展开方法,计算了中国大陆6级以上强震前的地震应变场,提取出震前时间因子的异常变化.计算结果分析发现大地震前时间因子在平稳背景上会出现突跳上升或突跳下降变化,且震前地震应变场前... 详细信息

以地震应变场作为地震活动的变量,通过自然正交函数展开方法,计算了中国大陆6级以上强震前的地震应变场,提取出震前时间因子的异常变化.计算结果分析发现大地震前时间因子在平稳背景上会出现突跳上升或突跳下降变化,且震前地震应变场前4个典型场中至少有3个典型场会出现异常变化,具有多分量显示异常的特点,而异常出现的最早时间大约在震前3年,并且一些地震前出现短临的时间因子异常变化特征.通过震例研究表明用地震应变场分析地震活动异常,提取的时间因子异常结果比应用地震能量场更具有独特的优越性,并讨论了应变场与能量场的差异.

关键词：地震应变场地震能量场自然正交函数展开方法时间因子

Synthesis,Structural Characterization of TTM-TTF Intercalated with Lamellar MnPS3

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Synthesis,Structural Characterization of TTM-TTF Intercalate...

Analysis of Micromechanical Properties at the Interface of Pre-wet SBS Modified Asphalt Mixture Based on Molecular Simulation Technology

第三届全国有机化学学术会议

作者： ZHANG, xuan CHEN, Xing-guo fu, Yang SU, xu QIN, Jin-Gui ( Department of Chemistry, Wuhan University, Wuhan 430072 )

＜正＞ Intercalation of organic species into layer inorganic solids provides a useful approach to creating ordered organic-inorganic nanocomposite materials with novel properties compared with the parent compounds, and hence has attracted much attention in recent years. Clement and co-workers had reported that an organic electron donor TTF monocation intercalated into the MPSs （M = Mn, Fe）, and the intercalates exhibited much higher conductivity than the corresponding pure host compounds. Our group also synthesized the intercalation compound of BEDT-TTF into MnPS3, which exhibits the room temperature conductivity of8.5×10-5 S/cm, 105 times higher than that of the

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 103-113页

作者： CHEN Wuxing CHEN Shuang YU Yan ZHANG Jiangyi xu Haiyang guo Wei School of Mines China University of Mining and TechnologyXuzhou 221000China College of Construction Engineering Jilin Uni-versityChangchun 130026China

The pre-wetting of aggregate surface is a means to improve the interface performance of SBS modified asphalt and *** effect of pre-wetting technology on the interaction between SBS modified asphalt and aggregate was analyzed by molecular dynamics *** diffusion coefficient and concentration distribution of SBS modified asphalt on aggregate surface are *** simulation results show that the diffusion coefficient of the aggregate surface of SBS modified asphalt is increased by 47.6%and 70.5%respectively after 110#asphalt and 130#asphalt are *** concentration distribution of SBS modified asphalt on the aggregate surface after pre-wetting is more *** to the results of interface energy calculation,the interface energy of SBS modified bitumen and aggregate can be increased by about 5%after *** to the results of molecular dynamics simulation,the pre-wetting technology can effectively improve the interface workability of SBS modified bitumen and aggregate,so as to improve the interface performance.

关键词： pre-wet oil-stone interface interface interaction interface mechanics molecular dynamics simulation

Zr/(Sc+Zr)微合金化对Al-Mg合金在热压缩变形中动态再结晶、位错密度和热加工性能的影响

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Transactions of Nonferrous Metals Society of China 2023年第3期33卷 668-682页

作者：邓英朱鑫文赖毅郭一帆傅乐徐国富黄继武中南大学材料科学与工程学院长沙410083 中南大学有色金属材料科学与工程湖南省重点实验室长沙410083 Applied Materials Science Department of Engineering ScienceUppsala UniversityUppsala75121Sweden

采用热压缩试验和电子显微分析方法研究Al-6.00Mg、Al-6.00Mg-0.10Zr和Al-6.00Mg-0.25Sc-0.10Zr (质量分数,%)合金的变形行为和显微组织特征。结果表明,在最大加工效率条件(673 K,0.01 s^(-1))下变形时,Al-6.00Mg、Al-6.00Mg-0.10Zr和Al-6.00Mg-0.25Sc-0.10Zr合金的位错密度分别为2.68×10^(16)、8.93×10^(16)和6.1×10^(17)m^(-2);其动态再结晶分数分别为19.8%、15.0%和12.7%。中心点平均取向差(KAM)分析表明,通过添加Zr或Sc+Zr,Al-Mg合金晶界附近的位错密度增加。此外,基于动态材料模型(DMM)建立的热加工图表明,添加Zr或Sc+Zr能减小Al-Mg合金的低温不稳定域的范围,但会增大高温和高应变不稳定域的范围。实验结果进一步证明,在变形条件下,仅Al-6.00Mg-0.25Sc-0.10Zr合金在773 K和1 s^(-1)时开裂。

关键词： Al-Mg合金 Sc Zr 热变形位错密度动态再结晶

Al-3Cu-0.5Sc合金高温变形的本构关系(英文)

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中国有色金属学会会刊：英文版 2013年第6期23卷 1549-1555页

作者：徐国富彭小燕梁霄鹏李旭尹志民中南大学材料科学与工程学院长沙410083 中南大学粉末冶金国家重点实验室长沙410083 中南大学有色金属材料科学与工程教育部重点实验室长沙410083

采用Gleeble-1500热/力模拟试验机研究Al-3Cu-0.5Sc合金在温度为350～500℃、应变速率为0.01～10s-1条件下的高温压缩变形行为。利用经摩擦修正和温度补偿修正后的流变应力曲线建立合金的本构方程,温度和应变速率对变形行为的影响可使... 详细信息

采用Gleeble-1500热/力模拟试验机研究Al-3Cu-0.5Sc合金在温度为350～500℃、应变速率为0.01～10s-1条件下的高温压缩变形行为。利用经摩擦修正和温度补偿修正后的流变应力曲线建立合金的本构方程,温度和应变速率对变形行为的影响可使用包含Zener-Holloman参数的指数方程来描述。通过考虑应变对材料常数的影响,建立包含真应变的本构方程;其真应变对本构方程的影响规律,可通过材料常数的四次多项式拟合来实现。

关键词： Al-3Cu-0.5Sc合金本构关系高温变形

Advances and applications in single-cell and spatial genomics

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Science China Life Sciences 2025年

作者： Jingjing Wang Fang Ye Haoxi Chai Yujia Jiang Teng Wang Xia Ran Qimin Xia Ziye xu Yuting fu guodong Zhang Hanyu Wu guoji guo Hongshan guo Yijun Ruan Yongcheng Wang Dong Xing xun xu Zemin Zhang Beijing Advanced Innovation Center for Genomics (ICG) Peking University Guangdong Provincial Key Laboratory of Genome Read and Write BGI Research Bone Marrow Transplantation Center of the First Affiliated Hospital & Liangzhu Laboratory Zhejiang University School of Medicine Life Sciences Institute and The Second Affiliated Hospital Zhejiang University BGI Research Biomedical Pioneering Innovation Center (BIOPIC) and School of Life Sciences Peking University Academy for Advanced Interdisciplinary Studies Peking University Institute of Hematology Zhejiang University Department of Laboratory Medicine of The First Affiliated Hospital & Liangzhu Laboratory Zhejiang University School of Medicine Center for Stem Cell and Regenerative Medicine Zhejiang University School of Medicine Zhejiang Provincial Key Lab for Tissue Engineering and Regenerative Medicine Dr.Li Dak Sum & Yip Yio Chin Center for Stem Cell and Regenerative Medicine

The applications of single-cell and spatial technologies in recent times have revolutionized the present understanding of cellular states and the cellular heterogeneity inherent in complex biological systems. These advancements offer unprecedented resolution in the examination of the functional genomics of individual cells and their spatial context within tissues. In this review, we have comprehensively discussed the historical development and recent progress in the field of single-cell and spatial genomics. We have reviewed the breakthroughs in single-cell multi-omics technologies, spatial genomics methods, and the computational strategies employed toward the analyses of singlecell atlas data. furthermore, we have highlighted the advances made in constructing cellular atlases and their clinical applications,particularly in the context of disease. Finally, we have discussed the emerging trends, challenges, and opportunities in this rapidly evolving field.

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