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Nonlinear Bending of FCC Nanoplates Based on a Quasi-Continuum Model

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Acta Mechanica Solida Sinica 2022年第6期35卷 1030-1039页

作者： Wenjing zhan Yaqi guo Ying Zhao guohua Nie School of Aerospace Engineering and Applied Mechanics Tongji UniversityShanghai200092China

A quasi-continuum model of plate-type nanomaterials with the face-centered cubic crystal structures is proposed in this *** fundamental governing equations for the nonlinear bending of the nanoplates are given by using the principle of minimum potential ***,the analytical solution is derived for cylindrical bending deformation of the structure under uniform transverse loading fixed at two sides based on the modified iterative method.A lattice finite element model is established to verify the present quasi-continuum ***,the corresponding solution by adopting the classical continuous plate theory is presented,in which two cases are considered for use of bulk values(limit values)and nanovalues of both elastic modulus and Poisson's *** difference among the quasi-continuum and continuous models are discussed by computation.

关键词： FCC Nanoplates Quasi-continuum model Size effect Nonlinear bending

中山大学科技期刊出版史略(1866—2024)

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中山大学学报（自然科学版）（中英文） 2025年第1期64卷 1-27页

作者：张冰詹拔群中山大学学报编辑部广东广州510275 中山大学期刊管理中心广东广州510275

本文力图较为完整地展现中山大学100多年的科技期刊出版历史全貌,在明晰中山大学办学源流的基础上将其前身各校的科技期刊出版情况纳入梳理,整理统计出中山大学及其前身各校在正式建校前(1866—1923年)出版科技期刊25种、建校后的民国时... 详细信息

本文力图较为完整地展现中山大学100多年的科技期刊出版历史全貌,在明晰中山大学办学源流的基础上将其前身各校的科技期刊出版情况纳入梳理,整理统计出中山大学及其前身各校在正式建校前(1866—1923年)出版科技期刊25种、建校后的民国时期(1924—1948年)出版科技期刊87种,共和国时期(1949—2024年)出版科技期刊60种,共计172种,并对代表性刊物进行简要介绍。中山大学的科技期刊出版以医学类期刊的贡献最为突出,其影响一直延续至今。这些科技期刊从科研学术角度记录了中山大学的学科发展历史,同时为中国近代科学技术的传播和发展作出了重要的贡献。

关键词：中山大学科技期刊出版史校史

守正创新勇担时代使命——中山大学学报自然科学版创刊70周年(1955—2024)

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中山大学学报（自然科学版）（中英文） 2025年第1期64卷 28-39页

作者：詹拔群张冰中山大学期刊管理中心广东广州510275 中山大学学报编辑部广东广州510275

本文介绍《中山大学学报(自然科学版中英文)》的创刊与源流,分为创刊初期(1955—1966)、首批复刊(1973—1978)、改革开放后(1979—2012)和迈进新时代(2013—2023)四个时间段回顾该刊70年的办刊历程,着重介绍了在各个时期为该刊的发展壮... 详细信息

本文介绍《中山大学学报(自然科学版中英文)》的创刊与源流,分为创刊初期(1955—1966)、首批复刊(1973—1978)、改革开放后(1979—2012)和迈进新时代(2013—2023)四个时间段回顾该刊70年的办刊历程,着重介绍了在各个时期为该刊的发展壮大作出了重要贡献的中山大学学者及其发表的成果,展现中山大学与该刊在推动国家科学技术发展进步方面所作出的贡献。新时代以来,自然科学版致力于内涵式高质量发展取得了成效。该刊以建设世界一流科技期刊为目标,采取了策划组织大型专题专辑、变更期刊文种为中英文、实施稿件质量提升计划、不断完善数字化出版等重要办刊举措,大力推进国际化高水平科技期刊建设。

关键词：科技期刊中山大学学报自然科学版重要作者数字化出版

The role of galectin-4 in physiology and diseases

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Protein & Cell 2016年第5期7卷 314-324页

作者： zhan-Qi Cao Xiu-Li guo Department of Pharmacology School of Pharmaceutical Sciences Shandong University Jinan 50012 China

Galectin-4, a tandem repeat member of the β-galactoside-binding proteins, possesses two carbohydraterecognition domains （CRD） in a single peptide chain. This lectin is mostly expressed in epithelial cells of the intestinal tract and secreted to the extracellular. The two domains have 40% similarity in amino acid sequence, but distinctly binding to various ligands. Just because the two domains bind to different ligands simultaneously, galectin-4 can be a crosslinker and crucial regulator in a large number of biological processes. Recent evidence shows that galectin-4 plays an important role in lipid raft stabilization, protein apical trafficking, cell adhesion, wound healing, intestinal inflammation, tumor progression, etc. This article reviews the physiological and pathological features of galectin-4 and its important role in such processes.

关键词： galectin-4 lipid raft crosslinker intestinalinflammation tumor progression

Recent Advances in Hydrometallation of Alkenes and Alkynes via the First Row Transition Metal Catalysis

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Chinese Journal of Chemistry 2018年第11期36卷 1075-1109页

作者： Jianhui Chen Jun guo zhan Lu College of Chemistry and Materials Engineering Wenzhou University Wenzhou Zhejiang 325035 China Department of chemistry Zhejiang University Hangzhou Zhejiang 310027China

Hydrometallation of alkenes and alkynes provides a straightforward route to access alkyl‐ or alkenyl‐metal reagents, which have a wide range of applications in organic transformations. In recent years, the first row transition metals (such as copper, nickel, cobalt, iron, etc.) have emerged high activity and selectivity in this area with the aid of a variety of ligands. This review covers the recent advances in the hydrometallation of minimally functionalized unsaturated C—C bonds (including alkenes, alkynes, dienes, allenes, enynes, etc.), as well as transformations involving catalytic hydrometallation process via the first row transition metal catalysis.

关键词： hydrometallation the first row transition metals alkenes alkynes metal‐hydride

Hydrothermal Synthesis and Crystal Structure of Inorganic-organic Hybrid Compound [H_3NC_2H_4NH_2]VOPO_4

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Chemical Research in Chinese Universities 2001年第3期17卷 249-252页

作者： zhanG dong SHI zhan FENG Shou-hua National Key Laboratory of Inorganic Synthesis&Preparative Chemistry Department of ChemistryJilin UniversityChangchun 130023P.R.China

An inorganic-organic hybrid compound, [H_3NC_2H_4NH_2]VOPO_4 was synthesized by means of the hydrothermal method. It was crystallized in a monoclinic system, a space group P2_1/c, with the crystal cell parameters: a=0.92285(11) nm, b=0.72994(9) nm, c=0.98495(11) nm, β=101.280(3)°, V=0.65067(13) nm^3, M_r=223.02 g/mol, D_c=2.277 g/cm^3, Z=4, R=0.0315, ωR=0.0865, GOF=1.085. The VO_5N octahedra chains are corner-linked by PO_4 tetrahedra; the VO_5N octahedra are all trans-linked with V—O bonds being alternately short and long. The monoprotonated ethylenediamine was intercalated between the layers with one end coordinating to V and the other end as an H-bond donor interacting with a terminal O atom of PO_4 from a neighboring sheet. The elementary analysis, infrared spectrum characters and thermal stability were also given.

关键词： Inorganic-organic hybrid material Hydrothermal synthesis Vanadium phosphate Crystal structure

Phosphorus migration mechanism between iron and high phosphorus gangue phase at high temperatures

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Journal of Iron and Steel Research International 2019年第2期26卷 113-122页

作者： Lei guo Jin-tao Gao Sheng-ping Zhong zhan-cheng guo State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

The phosphorus migration mechanism during melting separation of non-carbon-reduced high phosphorus iron ore was ***,the equilibrium compositions of hydrogen-reduced high phosphorus iron ore at different temperatures were simulated by the use of equilibrium composition module of HSC Chemistry ***,thermodynamic calculation was verified by the real heat treatment of simulated hydrogen-reduced high phosphorus iron ore with several pure reagents including self-made pure *** iron particles in the simulated samples gathered and grew up during heat ***,the hypoeutectic structure of Fe-P with grid shape of high phosphorus phase and circular shape of low phosphorus phase emerged within those iron *** the penetration of phosphorus from the periphery into the iron particles,the grid structure became denser and *** proves that the elemenlal phosphorus can be reduced from the gangue phase by metallic iron without solid carbon at high temperatures.

关键词： Melting separation Fluorapatite Thermodynamics Phosphorus migration High phosphorus iron ore

Robust neutralizing antibody response to the XBB.1.5 trivalent recombinant protein vaccine booster

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Signal Transduction and Targeted Therapy 2024年第9期9卷 3560-3562页

作者： Bing-dong zhan Xue-dong Song Xin Yu guo-Jian Yang Sheng Wan Mai-Juan Ma Quzhou Center for Disease Control and Prevention QuzhouChina State Key Laboratory of Pathogen and Biosecurity Academy of Military Medical SciencesBeijingChina Qujiang District Center for Disease Control and Prevention QuzhouChina Department of Microbiological Laboratory Technology School of Public HealthCheeloo College of MedicineShandong UniversityJinanChina

Dear Editor,The global prevalence of XBB subvariants,known for their significant immune evasion,has driven the development and adaptation of XBB *** XBB.1.5 mRNA vaccines have been developed and shown to provoke robust immune responses against XBB.1.5,EG.5.1,and BA.2.86 following vaccination.1 In June 2023,the XBB.1.5-recombinant COVID-19 trivalent(XBB.1.5+BA.5+Delta)protein vaccine(trivalent XBB.1.5 vaccine)(WestVac Biopharma Co.,Ltd.,China)was approved for emergency use against XBB *** preliminary data from the manufacturer suggest neutralization of several earlier Omicron subvariants and XBB.1.5,there is limited real-world evidence,and persisting immune imprinting may affect the induction of antibodies against new SARS-CoV-2 sublineages,2 such as JN.1,which has increased transmissibility and the ability to evade immunity.3 Additionally,subsequent XBB infection after BA.5/BF.7 breakthrough infection does not efficiently induce humoral immunity against JN.1,4 raising questions about the ability of the trivalent XBB.1.5 vaccine to provide adequate protection against this *** measured the neutralizing antibody responses in 32 individuals who experienced a BA.5/BF.7 breakthrough infection and a subsequent XBB infection before and after receiving the trivalent XBB.1.5 *** detailed demographic information of the study participants and their vaccination and infection histories are described in the Supplementary Methods.

关键词： valent neutral breakthrough

Altered 3D genome reorganization mediates precocious myeloid differentiation of aged hematopoietic stem cells in inflammation

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Science China Life Sciences 2025年

作者： Xinyu Cui Yu dong Qiang zhan Yixin Huang Qianshu Zhu Zihao zhang Guang Yang Liping Wang Shijun Shen Jia Zhao Zhiyi Lin Jiatong Sun Zhongqu Su Yihan Xiao Chuyu zhang Yuwei Liang Lu Shen Lichen Ji Xuguang zhang Jiqing Yin Hong Wang Zhiyang Chen Zhenyu Ju Cizhong Jiang Rongrong Le Shaorong Gao Clinical and Translational Research Center of Shanghai First Maternity & Infant Hospital Frontier Science Center for Stem Cells School of Life Sciences and Technology Tongji University Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education Orthopaedic Department of Tongji Hospital School of Life Sciences and Technology Tongji University Key Laboratory of Regenerative Medicine of Ministry of Education Institute of Aging and Regenerative Medicine Department of Developmental & Regenerative Medicine College of Life Science and Technology Jinan University Shandong Key Laboratory of Animal Bioengineering and Disease Prevention College of Animal Science and Technology Shandong Agricultural University Department of Joint Surgery Shanghai East Hospital Tongji University School of Medicine Shanghai Institute of Nutrition and Health Chinese Academy of Sciences

Inflammation is a driving force of hematopoietic stem cells(HSCs) aging, causing irreversible exhaustion of functional HSCs. However, the underlying mechanism of HSCs erosion by inflammatory insult remains poorly understood. Here, we find that transient LPS exposure primes aged HSCs to undergo accelerated differentiation at the expense of self-renewal, leading to depletion of HSCs. Meanwhile, the central regulator nuclear factor kappa B(NF-κB) mediating functional impairment by inflammation insult induces differential transcriptional response in aged HSCs compared with young HSCs, with precocious activation of myeloid lineage genes. Altered compartmentalization and chromatin loop formation are associated with aging-related differential transcriptional response in HSCs upon lipopolysaccharide(LPS)stimulation. Mechanistically, enhancer and promoter regions of myeloid lineage genes in aged HSCs are more accessible and display more rapid and prominent CTCF occupancy upon LPS stimulation. Our study provides comprehensive resources for the three-dimensional(3D)genome structure of HSCs and sheds light into the ordered genome organization and the associated transcriptome signature underlying HSCs aging.

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