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Optical coherence tomography assessment of edge dissections after drug-eluting stent implantation in coronary artery

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Chinese Medical Journal 2012年第6期125卷 1047-1050页

Background Edge dissections after coronary stent implantation are associated with increased short-term risk of major adverse cardiovascular events. The incidence and outcome of edge dissections after coronary stent implantation were reportedly different using different imaging techniques. We used optical coherence tomography （OCT） to assess the incidence, morphological findings and related factors of edge dissections after drug-eluting stent （DES） implantation. Methods Totally 42 patients with 43 de novo lesions in 43 native arteries undergoing DES implantation with OCT imaging were enrolled in this study. Results Nine edge dissections were detected in 43 arteries after DES implantation. There were four morphological patterns of stent edge dissections indentified in this study：（1） superficial intimal tears （n=3）, （2） subintimal dissections （n=4）, （3） split of media （n=1）, （4） disruption of the fibrotic cap of plaque （n=1）. Stent edge expansion and stent expansion were both higher in the group with dissections than those in the group without dissections （1.682±0.425 vs. 1.229±0.285, P=0.0290; 1.507±0.445 vs. 1.174±0.265, P=0.0072）. Conclusions The incidence of stent edge dissections detected by OCT was 21%. Stent edge dissection is related with stent edge expansion and stent expansion.

关键词： optical coherence tomography stent dissections

Coronary plaque response after drug eluting stent implantation assessed by serial optical coherence tomography analysis

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Chinese Medical Journal 2011年第22期124卷 3752-3756页

作者： tian feng chen yun-dai chen lian sun zhi-jun liu chang-fu guo jun jin qin-hua WANG jin-da gai lu-yue Department of Cardiology Chinese People＇s Liberation Army General Hospital Beijing 100853 China

Background In general, percutaneous coronary intervention （PCI） relieves vessel stenosis by implantation of a stent, however, the relationship between plaque characteristics and response after stenting is not clear. Methods We enrolled 68 patients （68 vessels） with diagnosed unstable angina pectoris that prospectively underwent PCI and an optical coherence tomography （OCT） examination was done before and after stenting. Coronary plaques were classified as fibrous, lipid-rich and calcified plaque according to OCT examination, and fibrous cap thickness, lumen eccentricity, stent expansion, stent malapposition, tissue prolapse, thrombosis, dissection and stent symmetry were noted. Results The frequency of prolapse was higher in lipid-rich plaques than fibrous plaques （85% vs. 40%, P 〈0.001）. Dissection most often occurred in fibrous plaque compared with lipid-rich and calcified plaques （60% vs. 32% vs. 29%, P 〈0.001）. The frequency of stent strut malapposition in calcified plaques was higher than firous and lipid-rich plaques （71% vs. 40% vs. 5%, P 〈0.001）. In-stent micro-thrombosis was detected only in lipid-rich plaques, with a frequency of 37% （15/41）. The risk factors of micro-thrombosis after PCI were cap thickness （OR 0.903, 95% CI 0.829-0.985）, lumen eccentricity （OR 1.147, 95% CI 1.012-1.30）, and stent length （OR 1.495, 95% CI 1.032-2.166）. Conclusion Plaque response after PCI is associated with its characteristics, and of those, micro-thrombosis after stenting in lipid-rich plaques was the most significant finding and can be predicted.

关键词： coronary heart disease, optical coherence tomography plaque, stent

Evaluation of neointimal coverage in patients with coronary artery aneurysm formation after drug-eluting stent implantation by optical coherence tomography

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Chinese Medical Journal 2013年第11期126卷 2092-2097页

作者： tian feng chen yun-dai chen lian sun zhi-jun guo jun jin qin-hua liu chang-N WANG jin-da liu hong-bin Department of Cardiology Chinese People's Liberation ArmyGeneral Hospital Beijing 100853 China

Background The vessel healing in patients with coronary artery aneurysms （CAA） that form after drug-eluting stent （DES） implantation is not clear. This study aims to assess the vessel healing in patients with CAA formation after DES implanation. Methods From june 2008 to August 2011, follow-up coronary angiography was conducted on 1160 patients who underwent percutaneous coronary intervention （PCI）. The average period of follow-up was about （18.95±13.05） months. A total of 175 patients who underwent DES implantation into de novo lesions and who underwent coronary angiography and optical coherence tomography （OCT） examination during follow-up were identified. Patients were divided into the CAA group （n=31） and non-CAA group （n=144） based on the results of the coronary angiography. The cardiac events including angina and acute myocardial infarction were noted; in addition, the neointimal thickness and the frequency of strut malapposition and strut uncoverage were also noted. Results A greater proportion of incomplete neointimal coverage （17.17% vs. 1.90%, P 〈0.001） and strut malapposition （18.20% vs. 1.38%, P 〈0.001） were observed in the CAA group. The neointimal thickness in the CAA group was significantly thinner than that in the non-CAA group （（146.6±94.8） μm vs. （192.5＋97.1）μm, P 〈0.001）, as detected via OCT. Patients with CAA formation had a higher frequency of cardiac events including angina pectoris （25.81% vs. 6.25%, P=0.001） and acute myocardial infarction （9.68% vs. 0.13%, P=0.002） and thrombosis （16.13% vs. 0.69%, P 〈0.001）. The longitudinal length of the CAA in the cardiac event group was significantly longer than in the no cardiac event group （（20.0±9.07） mm vs. （12.05±5.38） ram, P=0.005）. Conclusion CAA formation after DES implantation is frequently associated with cardiac events as a result of stent malapposition and incomplete neointimal coverage.

关键词： optical coherence tomography coronary artery aneurysms drug-eluting stent neointimal coverage

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-jun Bi Yuanjie Bi tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia hua Cai Wenyong Cai Wujun Cai yijian Cai yizhou Cai Yuchen Cai Haiying Cai huacheng Cai Lorenzo Calibbi junsong Cang guofu Cao Jianshe Cao Antoine Chance Xuejun chang yue chang Zhe chang Xinyuan chang Wei Chao Auttakit Chatrabhuti yimin Che Yuzhi Che bin chen Danping chen fuqing chen fusan chen Gang chen guoming chen hua-Xing chen Huirun chen jinhui chen Ji-Yuan chen Kai chen Mali chen Mingjun chen Mingshui chen Ning chen Shanhong chen Shanzhen chen Shao-Long chen Shaomin chen shiqiang chen tianlu chen Wei chen Xiang chen Xiaoyu chen Xin chen Xun chen Xurong chen Ye chen ying chen Yukai chen Zelin chen Zilin chen Gang chen Boping chen Chunhui chen Hok Chuen cheng huajie cheng Shan cheng Tongguang cheng yunlong Chi Pietro Chimenti Wen han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-yun dai Xinchen dai Xuwen dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-tian Deng zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP jinR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

Treatment of severely calcified coronary artery disease by intravascular lithotripsy primary outcomes and 180-day followup from the Chinese SOLSTICE Trial

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Journal of Geriatric Cardiology 2023年第1期20卷 32-39页

作者： feng tian Shan-Shan ZHOU jing-hua liu Hui chen zhi-jun sun lian chen Qi WANG jing jinG yun-dai chen Department of Cardiology Chinese PLA General HospitalBeijingChina Department of Cardiology Capital Medical University Affiliated Anzhen HospitalBeijingChina Department of Cardiology Capital Medical University Affiliated Beijing Friendship HospitalBeijingChina

OBJECTIVE To assess the safety and effectiveness of intravascular lithotripsy(IVL)treatment for de novo coronary lesion involving severely calcified vessels in a Chinese *** The Clinical Trial of the ShOckwave Coronary IVL System Used to Treat CalcIfied Coronary ArtEries(SOLSTICE)was a prospective,single-arm,multicentre *** to the inclusion criteria,patients with severely calcified lesions were enrolled in the *** was used to perform calcium modification prior to stent *** primary safety endpoint was freedom from major adverse cardiac events(MACEs)at 30 *** primary effectiveness endpoint was procedural success,defined as successful stent delivery with residual stenosischanges of calcium modification were assessed by optical coherence tomography(OCT)before and after IVL *** Patients(n=20)were enrolled at three sites in *** calcification by core lab assessment was present in all lesions,with a mean calcium angle and thickness of 300±51°and 0.99±0.12 mm(by OCT),*** 30-day MACE rate was 5%.Both primary safety and effectiveness endpoints were achieved in 95% of *** final in-stent diameter stenosis was 13.1%±5.7% with no patient had a residual stenosisluSIONS The initial coronary IVL experience for Chinese operators resulted in high procedural success and low angiographic complications consistent with prior IVL studies,reflecting the relative ease of use of IVL technology.

关键词： coronary intravascular closure

Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection:a randomized trial

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Signal Transduction and Targeted Therapy 2021年第10期6卷 3009-3018页

作者： jun liu Dan-Dan Li Wei Dong Yu-Qi liu yang Wu Da-Xuan Tang fu-Chun Zhang Meng Qiu Qi hua jing-Yu He jun Li Bai Du ting-Hai Du Lin-Lin Niu Xue-jun Jiang Bo Cui Jiang-bin chen yang-Gan Wang Hai-Rong Wang qin Yu jing He yi-Lin Mao Xiao-Fang bin yue Deng Yu-Dan tian qing-hua han Da-jin liu Li-qin Duan Ming-jun Zhao Cui-ying Zhang Hai-ying dai Ze-hua Li ying Xiao You-zhi Hu Xiao-Yu huang Kun Xing Xin Jiang Chao-feng liu jing An feng-Chun Li Tao Tao jin-Fa Jiang ying yang Yao-Rong Dong Lei Zhang Guang fu ying Li shu-Wei huang Li-Ping Dou Lan-jun sun ying-Qiang Zhao Jie Li yun Xia jun liu Fan liu Wen-jin He ying Li Jian-Cong Tan yang Lin Ya-bin Zhou Jian-Fei yang guo-qing Ma Hui-jun chen He-Ping liu Zong-Wu liu Jian-Xiong liu Xiao-Jia luo Xiao-hong bin Ya-Nan Yu Hai-Xia Dang bing Li Fei Teng Wang-Min Qiao Xiao-Long Zhu bing-Wei chen Qi-Guang chen Chun-Ti Shen Yong-Yan Wang yun-dai chen Zhong Wang Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijingChina Department of Cardiology Chinese PLA General HospitalBeijingChina Department of Cardiology Dongfang Hospital Affiliated to Beijing University of Chinese MedicineBeijingChina Department of Geratology Peking University Third HospitalBeijingChina Department of Cardiology Xuan Wu HospitalCapital Medical UniversityBeijingChina Department of Cardiology Guang'anmen HospitalChina Academy of Chinese Medical SciencesBeijingChina Department of Cardiology First Affiliated Hospital of Henan University of Chinese MedicineZhengzhouHenanChina Department of Cardiology Wuhan University Renmin HospitalWuhanHubeiChina Department of Cardiology Wuhan University Zhongnan HospitalWuhanHubeiChina Affiliated Zhongshan Hospital of Dalian University DalianLiaoningChina Department of Cardiology Second Affiliated Hospital to Hunan University of Chinese MedicineChangshaHunanChina Department of Cardiology First Affiliated Hospital to Changchun University of Chinese MedicineChangchunJilinChina Department of Cardiology First Affiliated Hospital to Shanxi Medical UniversityTaiyuanShanxiChina Department of Cardiology Affiliated Hospital of Shanxi University of Chinese MedicineXianyangShanxiChina Department of Cardiology Changsha Central HospitalChangshaHunanChina Department of Cardiology Hubei Provincial Hospital of Traditional Chinese MedicineWuhanHubeiChina Department of Cardiology Shanxi Provincial People's HospitalXi'anShanxiChina Department of Cardiology Shanxi Province Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Xi'an City Hospital of Traditional Chinese MedicineXi'anShanxiChina Department of Cardiology Shanghai Tongji HospitalShanghaiChina Department of Cardiology Shanghai Municipal Hospital of Traditional Chinese MedicineShanghaiChina Department of Cardiology The First Hospital of ChangshaChangshaHunanChina Department of Cardiology Xinhua Hospi

It's a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in thedfferentiated populations with complex diseases,as stable coronary heart ***,in an adaptive,31-center,randomized,double-blind trial invoving 920 patients with moderate symptomatic stable angina treated by 14-day Danhong injection(DHI),a kind of polyphamacological drug with high quality control,or placebo(0.9%saline),with 76-day following-up,we firstly confrmed that DHl couldincrease the proportion of patients with clinically significant changes on angina-frequency assessed by Seattle Angina Questionnaire(ASAQ-AF220)(12.78%at Day 30,95%confidence interval[C]5.86-19.71%,P=0.0003,13.82%at Day 6C0,95%CI 6.82-20.82%,P=0.0001and 8.95%at Day 90,95%CI 2.06-15.85%,P=0.01).We also found that there were no significant differences in new-onset major vascularevents(P=0.8502)and serious adverse events(P=0.9105)between DHl and *** performing the RNA sequencing in 62 selectedpatients,we developed a systemic modular approach tp identfy differentilly expressed modules(DEMs)of DHI with the Z_(summay)valueless than 0 compared with the control group,calculated by weighted gene co-expression network analysis(WGCNA),and sketched out thebasic framework on a modular map with 25 functional modules targeted by ***,the effective therapeutic module(ETM),defined as the highest corelation value with the phenotype alteration(SAQ-AF,the change in SAQ-AF at Day 30 from baseline)calculatedby WGCNA,was identifed in the population with the best effect(ASAQ-AF240),which is related to anticoagulation and regulation ofcholesterol *** assessed the modular flexbility of this ETM using the global topological D value based on Euclidean distance,which is corelated with phenotype alteration(r^(2):0.8204,P=0.019)by linear *** study identified the ant-angina therapeuticmodule in the effective population treated by the multi-target

关键词： angina injection sketch

光学相干断层成像与血管内超声评价冠状动脉斑块的病理对照研究

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中华心血管病杂志 2012年第4期40卷 302-306页

作者：郭军孙璐陈韵岱田峰刘宏斌陈练孙志军任艺虹金琴花刘长福韩宝石盖鲁粤杨庭树解放军总医院心内科北京100853 解放军总医院病理科北京100853

目的以尸检冠状动脉的病理诊断为对照，比较光学相干断层成像（OCT）与血管内超声（IVUS）识别及评价不同类型斑块的准确性。方法对15例尸检心脏的冠状动脉先行OCT和IVUS检查，然后制作病理切片。依据OCT和IVUS的判别标准将斑块分为3类... 详细信息

目的以尸检冠状动脉的病理诊断为对照，比较光学相干断层成像（OCT）与血管内超声（IVUS）识别及评价不同类型斑块的准确性。方法对15例尸检心脏的冠状动脉先行OCT和IVUS检查，然后制作病理切片。依据OCT和IVUS的判别标准将斑块分为3类：脂质斑块、钙化斑块和纤维斑块。以病理诊断为对照，比较OCT与IVUS识别不同类型斑块的敏感性和特异性。结果总共对77个冠状动脉斑块进行了分析。OCT识别脂质斑块、钙化斑块和纤维斑块的敏感性分别为69％、93％和88％，特异性分别为88％、92％和98％；IVUS识别脂质斑块、钙化斑块和纤维斑块的敏感性分别为6l％、98％和68％，特异性分别为92％、97％和90％。OCT与IVUS识别不同斑块的符合率为0．831（Kappa值=0．72，P〈0．01）。结论OCT和IVUS对不同类型斑块的识别有较好的准确性和一致性，而且OCT对纤维斑块的识别优于IVUS，对钙化斑块的识别并不优于IVUS。

关键词：体层摄影术,光学相干超声检查,介入性动脉粥样硬化

光学相干断层成像评价不同类型药物洗脱支架置入术后的内膜覆盖

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中华心血管病杂志 2011年第3期39卷 204-207页

作者：田峰陈韵岱陈练孙志军刘宏斌刘长福郭军王锦达解放军总医院心内科北京100853

目的应用光学相干断层成像（OCT）对比不同类型药物洗脱支架（DES）置人后的内膜覆盖情况。方法人选62例在我院置人DES（15．3±5．7）个月后行OCT检查的患者，依据置人支架类型分为Cypher支架组（病例数=26，支架数=57）、Endeavor支... 详细信息

目的应用光学相干断层成像（OCT）对比不同类型药物洗脱支架（DES）置人后的内膜覆盖情况。方法人选62例在我院置人DES（15．3±5．7）个月后行OCT检查的患者，依据置人支架类型分为Cypher支架组（病例数=26，支架数=57）、Endeavor支架组（病例数=17，支架数：23）和Firebird支架组（病例数=19，支架数=32）。对所有支架节段进行OCT检查后应用LightLab系统配备的软件进行图像分析。以64、168和366μm为分界点将增生内膜厚度进行区问划分，评价3种DES的内膜覆盖厚度以及内膜增生的匀称性。结果3组的内膜完全覆盖率差异无统计学意义（P〉0．05）。内膜增生厚度Cypher支架组为（178．7±11．9）μm、Endeavor支架组为（228．7±17．1）μm、Firebird支架组为（170．3±13．3）μm，任意2组间比较差异均有统计学意义（均P〈0．05）。Cypher支架组内膜增生均匀性优于Firebird支架组，Firebird支架组优于Endeavor支架组。结论不同类型DES置入后的内膜覆盖情况存在荠异。OCT可以评价不同类到DES问内障增毕均匀忡的善导．

关键词：冠状动脉疾病支架体层摄影术光学相干增生

光学相干断层成像评价药物洗脱支架置入术后晚期支架贴壁不良

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中华心血管病杂志 2009年第7期37卷 585-589页

作者：田峰陈韵岱孙志军陈练刘宏斌杨庭树刘长福金琴花白启才解放军总医院心内科北京100853

目的探讨药物洗脱支架（DES）置入术后晚期支架贴壁不良的特点。方法分析32例（包括51支血管、共置入71个支架）置入DES 1年后[（14．8±5．2）个月]行光学相干断层成像（OCT）检查的患者资料，对支架节段的OCT图像每间隔0．5mm取1帧图... 详细信息

目的探讨药物洗脱支架（DES）置入术后晚期支架贴壁不良的特点。方法分析32例（包括51支血管、共置入71个支架）置入DES 1年后[（14．8±5．2）个月]行光学相干断层成像（OCT）检查的患者资料，对支架节段的OCT图像每间隔0．5mm取1帧图像进行分析，找出贴壁不良的支架金属结构，测量支架到参照血管内壁的距离及支架表面内膜厚度，分析晚期支架贴壁不良的特点。结果OCT检查在7例（21．9％）患者中检出支架贴壁不良，其中4例合并支架段血管的正性重构，1例重叠置入支架，2例发现由血栓覆盖支架金属结构，7例患者随访期间无心脏不良事件发生。97．6％的支架金属结构完全贴壁并不同程度的内膜覆盖，2．4％的支架金属结构贴壁不良，包括1．2％的支架金属结构位于血管分支开口。位于血管分支开口的支架金属结构与其他贴壁不良支架表面的内膜覆盖厚度差异无统计学意义[（O．06±0．05）mm比（0．05±0．03）mm，P〉0．05]。结论晚期支架贴壁不良见于DES置入最初的贴壁不良、血管壁正性重构、重叠置入支架以及支架金属结构位于分支血管开口；贴壁不良的支架金属结构表面亦有不同程度的内膜覆盖。

关键词：冠状动脉疾病体层摄影术,光学相干支架